BRPI0909028A2 - nitroimidazóis bicíclicos covalentemente ligados a fenil oxazolidinonas substituídas, composições farmacêuticas e uso dos mesmos - Google Patents

nitroimidazóis bicíclicos covalentemente ligados a fenil oxazolidinonas substituídas, composições farmacêuticas e uso dos mesmos

Info

Publication number: BRPI0909028A2
Authority: BR; Brazil
Prior art keywords: pharmaceutical compositions; substituted phenyl; covalently linked; linked bicyclic; phenyl oxazolidinones
Prior art date: 2008-03-26

Application number

BRPI0909028A

Other languages

English (en)

Inventor

Adrian Blaser

Andrew M Thompson

Brian Desmond Palmer

Charles Z Ding

Dianjun D Chen

Genliang Lu

Hamish Scott Sutherland

Iveta Kmentova

Jiancheng Wang

Keith Combrink

Minsoo Song

William Alexander Denny

Zhenkun Ma

Original Assignee

Global Alliance For Tb Drug Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-03-26

Filing date

2009-03-25

Publication date

2015-09-22

2009-03-25 Application filed by Global Alliance For Tb Drug Dev filed Critical Global Alliance For Tb Drug Dev

2015-09-22 Publication of BRPI0909028A2 publication Critical patent/BRPI0909028A2/pt

Links

NCTCGHLIHJJIBK-UHFFFAOYSA-N 3-phenyl-1,3-oxazolidin-2-one Chemical class O=C1OCCN1C1=CC=CC=C1 NCTCGHLIHJJIBK-UHFFFAOYSA-N 0.000 title 1
-1 bicyclic nitroimidazoles Chemical class 0.000 title 1
239000008194 pharmaceutical composition Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BRPI0909028A 2008-03-26 2009-03-25 nitroimidazóis bicíclicos covalentemente ligados a fenil oxazolidinonas substituídas, composições farmacêuticas e uso dos mesmos BRPI0909028A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7085508P	2008-03-26	2008-03-26
PCT/US2009/038266 WO2009120789A1 (en)	2008-03-26	2009-03-25	Bicyclic nitroimidazoles covalently linked to substituted phenyl oxazolidinones

Publications (1)

Publication Number	Publication Date
BRPI0909028A2 true BRPI0909028A2 (pt)	2015-09-22

Family

ID=40821727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0909028A BRPI0909028A2 (pt)	2008-03-26	2009-03-25	nitroimidazóis bicíclicos covalentemente ligados a fenil oxazolidinonas substituídas, composições farmacêuticas e uso dos mesmos

Country Status (11)

Country	Link
US (1)	US7666864B2 (pt)
EP (1)	EP2254892B1 (pt)
JP (1)	JP5613656B2 (pt)
CN (1)	CN101965353B (pt)
AU (1)	AU2009228293B2 (pt)
BR (1)	BRPI0909028A2 (pt)
CA (1)	CA2712613C (pt)
NZ (1)	NZ587096A (pt)
RU (1)	RU2504547C2 (pt)
WO (1)	WO2009120789A1 (pt)
ZA (1)	ZA201006824B (pt)

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KR101650716B1 (ko) *	2012-11-22	2016-08-24	한국화학연구원	바이시클릭니트로이미다졸 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 결핵의 예방 또는 치료용 약학적 조성물
IN2013DE02954A (pt) *	2013-10-04	2015-04-10	Council Scient Ind Res
KR101564425B1 (ko)	2013-11-26	2015-10-30	한국화학연구원	신규한 바이사이클릭 니트로이미다졸 카바메이트 화합물, 이를 제조하는 방법 및 이를 유효성분으로 함유하는 결핵 질환의 예방 또는 치료용 약제학적 조성물
CN104725330B (zh) *	2013-12-18	2017-06-13	四川好医生药业集团有限公司	噁唑烷酮类化合物及其制备方法和用途
CN106928214A (zh) *	2014-09-17	2017-07-07	博瑞生物医药（苏州）股份有限公司	一种噁唑烷酮类化合物及其中间体的制备方法
KR101682356B1 (ko)	2014-11-04	2016-12-06	한국화학연구원	이미다조 옥사진 유도체, 이의 약학적으로 허용 가능한 염 또는 이의 광학이성질체 및 이를 유효성분으로 함유하는 약제학적 조성물
CN105732659B (zh) *	2014-12-12	2019-07-16	上海阳帆医药科技有限公司	硝基咪唑类化合物及其制备方法和在制药中的用途
EP3252059A4 (en)	2015-01-29	2018-07-11	Medshine Discovery Inc.	Anti-pulmonary tuberculosis nitroimidazole derivative
CN106317072B (zh) *	2015-06-17	2020-03-17	盟科医药技术(上海)有限公司	用于分枝杆菌感染治疗的杂环化合物及其应用
MD3316969T2 (ro)	2015-07-02	2022-07-31	Janssen Sciences Ireland Unlimited Co	Compuși antibacterieni
US10550092B2 (en) *	2015-07-17	2020-02-04	The Global Alliance For Tb Drug Development, Inc.	Substituted phenyloxazolidinones for antimicrobial therapy
MA45377A (fr)	2016-06-16	2019-04-24	Janssen Sciences Ireland Unlimited Co	Composés hétérocycliques en tant qu'agents antibacteriens
MA47676A (fr)	2017-03-01	2021-06-02	Janssen Sciences Ireland Unlimited Co	Polythérapie
CN107827927B (zh) *	2017-09-05	2019-08-09	陕西思尔生物科技有限公司	一种镍催化合成磷酸泰地唑利的方法
CN108047248A (zh) *	2018-02-12	2018-05-18	丹诺医药(苏州）有限公司	噁唑烷酮-硝基咪唑类偶联分子的应用
CN111606900A (zh) *	2019-02-24	2020-09-01	陕西合成药业股份有限公司	一种抗感染药物及其制备方法和应用
CN112300192B (zh) *	2019-08-02	2023-08-11	南京长澳医药科技有限公司	硝基咪唑类化合物及其制备方法和用途
CN113527331B (zh) *	2020-04-17	2024-05-28	南京长澳医药科技有限公司	硝基咪唑类衍生物及其制备方法和用途

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US20100286211A1 (en)	2004-10-08	2010-11-11	Biswajit Das	Oxazolidinone derivatives as antimicrobials
WO2006043121A1 (en)	2004-10-20	2006-04-27	Ranbaxy Laboratories Limited	Oxazolidinone derivatives as antimicrobials
JP2009521464A (ja) *	2005-12-23	2009-06-04	ノバルティスアクチエンゲゼルシャフト	ニトロイミダゾール化合物

2009
- 2009-03-25 CN CN200980108015.7A patent/CN101965353B/zh active Active
- 2009-03-25 NZ NZ587096A patent/NZ587096A/en unknown
- 2009-03-25 WO PCT/US2009/038266 patent/WO2009120789A1/en not_active Ceased
- 2009-03-25 JP JP2011502023A patent/JP5613656B2/ja active Active
- 2009-03-25 EP EP09724981.7A patent/EP2254892B1/en active Active
- 2009-03-25 BR BRPI0909028A patent/BRPI0909028A2/pt not_active Application Discontinuation
- 2009-03-25 RU RU2010143541/04A patent/RU2504547C2/ru active
- 2009-03-25 AU AU2009228293A patent/AU2009228293B2/en active Active
- 2009-03-25 CA CA2712613A patent/CA2712613C/en active Active
- 2009-03-25 US US12/411,220 patent/US7666864B2/en active Active
2010
- 2010-09-23 ZA ZA2010/06824A patent/ZA201006824B/en unknown

Also Published As

Publication number	Publication date
ZA201006824B (en)	2011-06-29
US7666864B2 (en)	2010-02-23
CN101965353B (zh)	2014-12-17
EP2254892A1 (en)	2010-12-01
RU2504547C2 (ru)	2014-01-20
CN101965353A (zh)	2011-02-02
CA2712613A1 (en)	2009-10-01
NZ587096A (en)	2011-11-25
US20090281088A1 (en)	2009-11-12
AU2009228293B2 (en)	2012-11-08
WO2009120789A8 (en)	2010-10-28
WO2009120789A1 (en)	2009-10-01
RU2010143541A (ru)	2012-05-10
AU2009228293A1 (en)	2009-10-01
EP2254892B1 (en)	2014-04-23
JP5613656B2 (ja)	2014-10-29
CA2712613C (en)	2017-02-28
JP2011515487A (ja)	2011-05-19

Legal Events

Date	Code	Title	Description
2017-06-13	B25A	Requested transfer of rights approved	Owner name: TENNOR THERAPEUTICS LIMITED (CN)
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-02-12	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2019-03-12	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2019-07-09	B09B	Patent application refused [chapter 9.2 patent gazette]

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