BRPI0909211A2 - formulação orais e injetáveis de composto de tetraciclina - Google Patents

formulação orais e injetáveis de composto de tetraciclina

Info

Publication number
BRPI0909211A2
BRPI0909211A2 BRPI0909211A BRPI0909211A BRPI0909211A2 BR PI0909211 A2 BRPI0909211 A2 BR PI0909211A2 BR PI0909211 A BRPI0909211 A BR PI0909211A BR PI0909211 A BRPI0909211 A BR PI0909211A BR PI0909211 A2 BRPI0909211 A2 BR PI0909211A2
Authority
BR
Brazil
Prior art keywords
oral
injectable formulations
tetracycline compound
tetracycline
compound
Prior art date
Application number
BRPI0909211A
Other languages
English (en)
Inventor
Sean Johnston
Original Assignee
Paratek Pharm Innc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41114256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0909211(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Paratek Pharm Innc filed Critical Paratek Pharm Innc
Priority to BR122020011180A priority Critical patent/BR122020011180B8/pt
Publication of BRPI0909211A2 publication Critical patent/BRPI0909211A2/pt
Publication of BRPI0909211B1 publication Critical patent/BRPI0909211B1/pt
Publication of BRPI0909211B8 publication Critical patent/BRPI0909211B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0909211A 2008-03-28 2009-03-30 formulação oral em forma de comprimido de compostos de tetraciclina BRPI0909211B8 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122020011180A BR122020011180B8 (pt) 2008-03-28 2009-03-30 formulações injetáveis de compostos de tetraciclina

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4039808P 2008-03-28 2008-03-28
US61/040,398 2008-03-28
PCT/US2009/001973 WO2009120389A1 (en) 2008-03-28 2009-03-30 Oral and injectable formulations of tetracycline compounds

Publications (3)

Publication Number Publication Date
BRPI0909211A2 true BRPI0909211A2 (pt) 2016-11-29
BRPI0909211B1 BRPI0909211B1 (pt) 2020-08-25
BRPI0909211B8 BRPI0909211B8 (pt) 2021-05-25

Family

ID=41114256

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0909211A BRPI0909211B8 (pt) 2008-03-28 2009-03-30 formulação oral em forma de comprimido de compostos de tetraciclina
BR122020011180A BR122020011180B8 (pt) 2008-03-28 2009-03-30 formulações injetáveis de compostos de tetraciclina

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122020011180A BR122020011180B8 (pt) 2008-03-28 2009-03-30 formulações injetáveis de compostos de tetraciclina

Country Status (30)

Country Link
US (2) US9314475B2 (pt)
EP (3) EP3348258B1 (pt)
JP (8) JP2011515473A (pt)
KR (3) KR101893740B1 (pt)
CN (1) CN102046177B (pt)
AU (1) AU2009229174A1 (pt)
BR (2) BRPI0909211B8 (pt)
CA (2) CA2719751C (pt)
CL (1) CL2010000281A1 (pt)
CO (1) CO6300935A2 (pt)
CY (2) CY1120240T1 (pt)
DK (2) DK3348258T3 (pt)
EC (1) ECSP10010576A (pt)
ES (2) ES2836448T3 (pt)
HR (2) HRP20180836T1 (pt)
HU (2) HUE038257T2 (pt)
IL (1) IL208440A0 (pt)
LT (2) LT2271348T (pt)
MA (1) MA32275B1 (pt)
MX (1) MX2010010585A (pt)
NO (1) NO2271348T3 (pt)
NZ (1) NZ588428A (pt)
PL (2) PL2271348T3 (pt)
PT (2) PT2271348T (pt)
RU (1) RU2010144130A (pt)
SI (2) SI3348258T1 (pt)
TR (1) TR201806893T4 (pt)
UA (2) UA109627C2 (pt)
WO (1) WO2009120389A1 (pt)
ZA (1) ZA201007013B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090253660A1 (en) * 2008-03-05 2009-10-08 Paratek Pharmaceuticals, Inc. Minocycline Compounds and Methods of Use Thereof
TWI680117B (zh) * 2008-05-19 2019-12-21 派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
JP6025712B2 (ja) 2010-05-12 2016-11-16 レンペックス・ファーマシューティカルズ・インコーポレイテッド テトラサイクリン組成物
WO2017192516A1 (en) * 2016-05-02 2017-11-09 Paratek Pharmaceuticals, Inc. 9-aminomethyl minocycline compounds and methods of use thereof in urinary tract infection (uti) treatment
US10166912B2 (en) 2016-08-19 2019-01-01 Sl Corporation Automotive LED driving apparatus
SG10201913599RA (en) 2016-11-01 2020-02-27 Paratek Pharm Innc 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
EP3746059B1 (en) 2018-01-31 2026-03-04 Deciphera Pharmaceuticals, LLC Combination therapy for the treatment of gastrointestinal stromal tumors
MX2021002503A (es) 2018-09-04 2021-06-15 Paratek Pharm Innc Métodos de tratamiento de infecciones micobacterianas usando compuestos de tetraciclina.
AU2020419197B2 (en) * 2019-12-30 2023-08-31 Deciphera Pharmaceuticals, Llc Amorphous kinase inhibitor formulations and methods of use thereof
PT117254B (pt) 2021-05-26 2024-04-18 Hovione Farm S A Método de síntese de compostos 9-aminometil tetraciclinas

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2699054A (en) * 1953-10-09 1955-01-11 Lloyd H Conover Tetracycline
US2712517A (en) * 1954-03-03 1955-07-05 Bristol Lab Inc Production of tetracycline and substituted tetracyclines
US3019173A (en) * 1956-06-04 1962-01-30 American Cyanamid Co Method for preparing tetracycline
US2990331A (en) 1956-11-23 1961-06-27 Pfizer & Co C Stable solutions of salts of tetracyclines for parenteral administration
US3005023A (en) * 1957-04-05 1961-10-17 American Cyanamid Co Production of tetracycline
US2980584A (en) 1957-10-29 1961-04-18 Pfizer & Co C Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
US2886595A (en) * 1958-09-30 1959-05-12 Bristol Lab Inc Tetracycline recovery
US3062717A (en) 1958-12-11 1962-11-06 Pfizer & Co C Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
US3019260A (en) * 1959-05-13 1962-01-30 American Cyanamid Co Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
FR1430859A (pt) * 1960-05-23 1966-05-25
US3165531A (en) 1962-03-08 1965-01-12 Pfizer & Co C 13-substituted-6-deoxytetracyclines and process utilizing the same
US3301899A (en) * 1963-11-27 1967-01-31 Bristol Myers Co Purification of tetracycline
US3454697A (en) 1965-06-08 1969-07-08 American Cyanamid Co Tetracycline antibiotic compositions for oral use
NL6607516A (pt) 1966-05-31 1967-12-01
DE1767891C3 (de) 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
US3957980A (en) 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
DE2442829A1 (de) 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4018889A (en) 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4126680A (en) 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
DE122006000058I2 (de) 1991-10-04 2007-09-13 Wyeth Corp 7-Substituierte-9-substituierte Amino-6-Demethyl-6-Deoxy-Tetracycline
US5494903A (en) * 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US6465431B1 (en) * 1999-11-17 2002-10-15 Boston Life Sciences, Inc. Pharmaceutical compositions comprising troponin subunits, fragments and homologs thereof and methods of their use to inhibit angiogenesis
EP1023065A1 (en) 1997-08-29 2000-08-02 Dsm N.V. Granules free of excipients
KR100252699B1 (ko) * 1998-03-17 2000-12-01 강재헌 치주염 치료용 미노사이클린 조성물
ATE336238T1 (de) 1998-11-18 2006-09-15 Collagenex Pharm Inc Neue 4-dedimethylaminotetracyclinderivate
US6448323B1 (en) 1999-07-09 2002-09-10 Bpsi Holdings, Inc. Film coatings and film coating compositions based on polyvinyl alcohol
JP4516711B2 (ja) * 1999-12-28 2010-08-04 中外製薬株式会社 安定な抗体組成物及び注射製剤
SI1301467T1 (sl) * 2000-07-07 2007-02-28 Tufts College 9-substituirane minociklinske spojine
EP1368305B1 (en) 2001-03-13 2008-08-13 Paratek Pharmaceuticals, Inc. 7, 9-substituted tetracycline compounds
US7553828B2 (en) * 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
WO2002072031A2 (en) * 2001-03-14 2002-09-19 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
JP2004537544A (ja) * 2001-07-13 2004-12-16 パラテック ファーマシューティカルズ インコーポレイテッド 標的治療活性を有するテトラサイクリン化合物
EP1482926A4 (en) * 2002-03-08 2006-04-12 Paratek Pharm Innc AMINO METHYL SUBSTITUTED TETRACYCLINE COMPOUNDS
CN1390550A (zh) * 2002-07-25 2003-01-15 于航 盐酸米诺环素冻干粉针剂及其制备方法
AU2003287218C1 (en) * 2002-10-24 2010-07-15 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
CA2503446C (en) * 2002-10-24 2012-12-18 Paratek Pharmaceuticals, Inc. Methods of using substituted tetracycline compounds to modulate rna
US20040121003A1 (en) 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
WO2004064728A2 (en) * 2003-01-16 2004-08-05 Paratek Pharmaceuticals, Inc. Use of specific tetracycline compounds in therapy
CN1700906A (zh) * 2003-02-03 2005-11-23 新药物公司 稳定的无菌过滤性脂质体包封的紫杉烷和其他抗肿瘤药物
WO2004078111A2 (en) 2003-03-06 2004-09-16 Ranbaxy Laboratories Limited Extended release minocycline compositions and processes for their preparation
WO2004091513A2 (en) * 2003-04-10 2004-10-28 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
JP4738333B2 (ja) * 2003-07-09 2011-08-03 パラテック ファーマシューティカルズ インコーポレイテッド 9−アミノメチルテトラサイクリン化合物のプロドラッグ
EP1648859B1 (en) * 2003-07-09 2013-02-27 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
US7786099B2 (en) * 2004-01-15 2010-08-31 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
ES2434944T5 (es) * 2005-03-14 2022-10-20 Wyeth Llc Composiciones de tigeciclina y procedimientos de preparación
US9078811B2 (en) 2006-01-24 2015-07-14 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
US20090246276A1 (en) * 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
US20090253660A1 (en) * 2008-03-05 2009-10-08 Paratek Pharmaceuticals, Inc. Minocycline Compounds and Methods of Use Thereof

Also Published As

Publication number Publication date
ZA201007013B (en) 2013-11-27
AU2009229174A1 (en) 2009-10-01
KR101835574B1 (ko) 2018-03-08
LT2271348T (lt) 2018-06-25
JP2025137721A (ja) 2025-09-19
CA2719751A1 (en) 2009-10-01
BRPI0909211B8 (pt) 2021-05-25
WO2009120389A1 (en) 2009-10-01
EP3348258B1 (en) 2020-09-09
HK1257928A1 (en) 2019-11-01
CY1120240T1 (el) 2019-07-10
PT2271348T (pt) 2018-04-16
NO2271348T3 (pt) 2018-08-25
HRP20180836T1 (hr) 2018-07-27
PT3348258T (pt) 2020-11-25
CN102046177A (zh) 2011-05-04
NZ588428A (en) 2012-08-31
JP6412521B2 (ja) 2018-10-24
EP2271348A1 (en) 2011-01-12
BR122020011180B1 (pt) 2021-03-23
KR101746228B1 (ko) 2017-06-12
JP2019196408A (ja) 2019-11-14
ES2836448T3 (es) 2021-06-25
KR20110008057A (ko) 2011-01-25
CA2984301C (en) 2020-10-27
SI2271348T1 (en) 2018-08-31
CY1123382T1 (el) 2021-12-31
CL2010000281A1 (es) 2012-03-30
US20100056638A1 (en) 2010-03-04
CA2719751C (en) 2018-01-02
MX2010010585A (es) 2010-11-09
DK3348258T3 (da) 2020-12-07
TR201806893T4 (tr) 2018-06-21
JP2011515473A (ja) 2011-05-19
MA32275B1 (fr) 2011-05-02
KR101893740B1 (ko) 2018-08-30
CA2984301A1 (en) 2009-10-01
SI3348258T1 (sl) 2020-12-31
JP2023144043A (ja) 2023-10-06
JP6577645B2 (ja) 2019-09-18
EP2271348B1 (en) 2018-03-28
JP2021167355A (ja) 2021-10-21
LT3348258T (lt) 2020-12-10
HRP20201883T1 (hr) 2021-01-22
KR20160105532A (ko) 2016-09-06
JP2018203778A (ja) 2018-12-27
HUE038257T2 (hu) 2018-10-29
BRPI0909211B1 (pt) 2020-08-25
JP2016145260A (ja) 2016-08-12
PL3348258T3 (pl) 2021-03-08
CO6300935A2 (es) 2011-07-21
UA109627C2 (uk) 2015-09-25
CN102046177B (zh) 2012-12-19
DK2271348T3 (en) 2018-06-14
PL2271348T3 (pl) 2018-08-31
BR122020011180B8 (pt) 2021-07-27
EP3789030A1 (en) 2021-03-10
US9314475B2 (en) 2016-04-19
UA122762C2 (uk) 2021-01-06
KR20180026799A (ko) 2018-03-13
JP5940119B2 (ja) 2016-06-29
US20160279151A1 (en) 2016-09-29
EP2271348A4 (en) 2011-05-25
ES2674708T3 (es) 2018-07-03
EP3348258A1 (en) 2018-07-18
IL208440A0 (en) 2010-12-30
ECSP10010576A (es) 2010-12-30
RU2010144130A (ru) 2012-05-10
WO2009120389A8 (en) 2010-05-14
JP2014221820A (ja) 2014-11-27
HUE052201T2 (hu) 2021-04-28

Similar Documents

Publication Publication Date Title
LT3692983T (lt) Citidino analogų peroralinės kompozicijos ir jų naudojimo būdai
PT2448582T (pt) Compostos e composições terapêuticas
BRPI0914427A2 (pt) composição dental endurecivel
BRPI0914713A2 (pt) composição para cuidado oral
BRPI0906980A2 (pt) Composição de derivados e maleatados
LTC2323972I2 (lt) C7-fluoru pakeisti tetraciklino junginiai
EP2240022A4 (en) PHARMACEUTICAL COMPOSITIONS
BRPI0923836A2 (pt) Composições farmacêuticas orais contendo opióide e métodos
EP2373681A4 (en) PHARMACEUTICAL COMPOSITIONS
BRPI0918206A2 (pt) derivados de animoéster e composição medicinal destes
IL208440A0 (en) Oral and injectable formulations of tetracycline compounds
EP2241304A4 (en) ORAL DENTAL COMPOSITION
LT2966175T (lt) Farmacinės kompozicijos turinčios korteksolono-17-alfa-propionato
BRPI0913521A2 (pt) composição dental endurecível e artigo dental
BRPI0908132A2 (pt) Composto de benzodiazepina e composição farmacêutica
EP2236149A4 (en) MEDICAL COMPOSITION
BRPI0913398A2 (pt) composição e métodos de adesivo para dentaduras
PL2173345T3 (pl) Doustna formulacja metadoksyny
EP2305205A4 (en) COMPOSITION FOR TEETH
EP2341773A4 (en) PHARMACEUTICAL COMPOSITIONS FROM ATORVASTATIN
SMT201400053B (it) Forme farmaceutiche orali di bendamustina
EP2185112A4 (en) Stabilized therapeutic compositions and formulations
BRPI0913610A2 (pt) métodos e composições para tratamento bucal
BRPI1007515A2 (pt) formulações orais sólidas de uma piridopirimidinona
EP2310009A4 (en) PARENTERAL AND ORAL ADMINISTRATIVE FORMULATIONS FROM BENZIMIDAZOLENE

Legal Events

Date Code Title Description
B15I Others concerning applications: loss of priority

Free format text: PERDA DA PRIORIDADE US 61/040,398 DE 28/03/2008 REIVINDICADA NO PCT/US2009/001973 POR NAO CUMPRIMENTO DA EXIGENCIA PUBLICADA NA RPI 2389 DE 18/10/2016 DE MANEIRA SATISFATORIA. O DIREITO DE PRIORIDADE NAO PODE SER EXTRAPOLADO DE UM PEDIDO PARA OUTRO, DESTA FORMA, A CESSAO ENVIADA PARA O PEDIDO DE PATENTE US 12/414,612 DE 30/03/2009, MESMO ESTE REIVINDICANDO A PRIORIDADE DO PEDIDO US 61/040,398 DE 28/03/2008, NAO PODE SER CONSIDERADA VALIDA.

B12F Other appeals [chapter 12.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 25/08/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/03/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF