BRPI0909840A2 - Uso de 4-tio-2-deoxinucleosídios - Google Patents

Uso de 4-tio-2-deoxinucleosídios

Info

Publication number
BRPI0909840A2
BRPI0909840A2 BRPI0909840-2A BRPI0909840A BRPI0909840A2 BR PI0909840 A2 BRPI0909840 A2 BR PI0909840A2 BR PI0909840 A BRPI0909840 A BR PI0909840A BR PI0909840 A2 BRPI0909840 A2 BR PI0909840A2
Authority
BR
Brazil
Prior art keywords
deoxynucleosides
thio
Prior art date
Application number
BRPI0909840-2A
Other languages
English (en)
Inventor
John A Secrist Iii
Kamal N Tiwari
Joseph A Maddry
Original Assignee
Southern Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Res Inst filed Critical Southern Res Inst
Publication of BRPI0909840A2 publication Critical patent/BRPI0909840A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0909840-2A 2008-03-12 2009-03-12 Uso de 4-tio-2-deoxinucleosídios BRPI0909840A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/047,197 US8859589B2 (en) 2008-03-12 2008-03-12 Use of 4′-thio-2′-deoxynucleosides as anti orthopoxvirus agents
PCT/US2009/036869 WO2009114651A2 (en) 2008-03-12 2009-03-12 Use of '-thio-2'-deoxynucleosides as anri orthopoxvirus agents

Publications (1)

Publication Number Publication Date
BRPI0909840A2 true BRPI0909840A2 (pt) 2015-07-28

Family

ID=41065824

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909840-2A BRPI0909840A2 (pt) 2008-03-12 2009-03-12 Uso de 4-tio-2-deoxinucleosídios

Country Status (12)

Country Link
US (1) US8859589B2 (pt)
EP (1) EP2262365B1 (pt)
JP (1) JP5543930B2 (pt)
KR (1) KR20100132503A (pt)
CN (1) CN101959407A (pt)
AU (1) AU2009223064B8 (pt)
BR (1) BRPI0909840A2 (pt)
CA (1) CA2718175C (pt)
EA (1) EA017705B1 (pt)
MX (1) MX2010010082A (pt)
NZ (1) NZ587915A (pt)
WO (1) WO2009114651A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201603288XA (en) 2012-03-28 2016-05-30 Fujifilm Corp Salt Of 1-(2-Deoxy-2-Fluoro-4-Thio-beta-D-Arabinofuranosyl)Cytosine
KR20170001722A (ko) 2012-08-13 2017-01-04 후지필름 가부시키가이샤 1-(2-데옥시-2-플루오로-4-티오-β-D-아라비노푸라노실)시토신의 합성 중간체, 티오뉴클레오시드의 합성 중간체, 및 그들의 제조법
EP3109245B1 (en) 2014-02-18 2018-01-03 FUJIFILM Corporation Method for producting thiolane skeleton-type glycoconjugate, and thiolane skeleton-type glycoconjugate
JP6204223B2 (ja) 2014-02-19 2017-09-27 富士フイルム株式会社 チオピラノース化合物等の製造方法
TWI678373B (zh) 2014-10-31 2019-12-01 日商富士軟片股份有限公司 硫代核苷衍生物或其鹽及醫藥組合物
IL265044B2 (en) 2016-08-31 2025-02-01 Fujifilm Corp An antitumor preparation containing the substances nab-paclitaxel and 1-(2-deoxy-2-fluoro-4-thio-D-beta-arabinofurnosyl)cytosine, a kit containing these substances and their uses
WO2019146130A1 (ja) 2018-01-29 2019-08-01 富士フイルム株式会社 胆道がん用抗腫瘍剤および胆道がんの処置方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591722A (en) * 1989-09-15 1997-01-07 Southern Research Institute 2'-deoxy-4'-thioribonucleosides and their antiviral activity
IE74701B1 (en) 1989-10-04 1997-07-30 Univ Birmingham Further antiviral pyrimidine nucleosides
US5521163A (en) * 1990-07-13 1996-05-28 University Of Birmingham Antiviral pyrimidine nucleosides and methods for using same
US20050053626A1 (en) * 2003-09-05 2005-03-10 Harrington John Ames Grace process biotechnology patent the cure to the herpes virus
EP2842559A3 (en) 2005-04-08 2015-03-18 Chimerix, Inc. Compounds, compositions and methods for the treatment of viral infections and other medical disorders

Also Published As

Publication number Publication date
WO2009114651A2 (en) 2009-09-17
JP2011526242A (ja) 2011-10-06
US8859589B2 (en) 2014-10-14
WO2009114651A3 (en) 2010-03-18
MX2010010082A (es) 2011-06-01
AU2009223064B8 (en) 2014-01-16
CN101959407A (zh) 2011-01-26
CA2718175C (en) 2016-06-28
KR20100132503A (ko) 2010-12-17
WO2009114651A8 (en) 2009-12-03
AU2009223064A1 (en) 2009-09-17
EP2262365B1 (en) 2016-11-16
EA201070887A1 (ru) 2011-06-30
EA017705B1 (ru) 2013-02-28
US20120136017A1 (en) 2012-05-31
EP2262365A2 (en) 2010-12-22
AU2009223064B2 (en) 2013-08-29
NZ587915A (en) 2012-02-24
CA2718175A1 (en) 2009-09-17
JP5543930B2 (ja) 2014-07-09
EP2262365A4 (en) 2011-06-29

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 11A ANUIDADE.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2557 DE 07/01/2020.