BRPI0910236A2 - método para cristalização de composto - Google Patents

método para cristalização de composto

Info

Publication number
BRPI0910236A2
BRPI0910236A2 BRPI0910236A BRPI0910236A BRPI0910236A2 BR PI0910236 A2 BRPI0910236 A2 BR PI0910236A2 BR PI0910236 A BRPI0910236 A BR PI0910236A BR PI0910236 A BRPI0910236 A BR PI0910236A BR PI0910236 A2 BRPI0910236 A2 BR PI0910236A2
Authority
BR
Brazil
Prior art keywords
compound crystallization
crystallization
compound
Prior art date
Application number
BRPI0910236A
Other languages
English (en)
Inventor
Komatsu Hidetaka
Satoh Hiroya
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Publication of BRPI0910236A2 publication Critical patent/BRPI0910236A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI0910236A 2008-03-24 2009-03-18 método para cristalização de composto BRPI0910236A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008076124 2008-03-24
PCT/JP2009/055235 WO2009119395A1 (ja) 2008-03-24 2009-03-18 ２－アミノ－２－［２－［４－（３－ベンジルオキシフェニルチオ）－２－クロロフェニル］エチル］－１，３－プロパンジオール塩酸塩の結晶化方法

Publications (1)

Publication Number Publication Date
BRPI0910236A2 true BRPI0910236A2 (pt) 2019-09-24

Family

ID=41113592

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0910236A BRPI0910236A2 (pt) 2008-03-24 2009-03-18 método para cristalização de composto

Country Status (13)

Country Link
US (2) US9493410B2 (pt)
EP (2) EP2269982B1 (pt)
JP (1) JP5344320B2 (pt)
KR (2) KR101767019B1 (pt)
CN (2) CN102046594A (pt)
AU (1) AU2009230269B2 (pt)
BR (1) BRPI0910236A2 (pt)
CA (1) CA2718987C (pt)
ES (1) ES2572893T3 (pt)
MX (1) MX2010010429A (pt)
RU (1) RU2482110C2 (pt)
TW (1) TWI429621B (pt)
WO (1) WO2009119395A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8476305B2 (en) 2008-02-07 2013-07-02 Kyorin Pharmaceutical Co., Ltd. Therapeutic agent or prophylactic agent for inflammatory bowel disease comprising amino alcohol derivative as active ingredient
US9315453B2 (en) 2012-04-18 2016-04-19 Kyorin Pharmaceutical Co., Ltd. 4-(3-benzyloxyphenylthio)-2-chloro-1-(3-nitropropyl)benzene crystal
WO2021084068A1 (en) 2019-10-31 2021-05-06 Idorsia Pharmaceuticals Ltd Combination of a cxcr7 antagonist with an s1p1 receptor modulator
CN119857281B (zh) * 2025-03-25 2025-06-06 河南永源化工原料有限公司 一种三乙胺盐酸盐冷冻结晶设备及工艺

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5475138A (en) 1994-07-07 1995-12-12 Pharm-Eco Laboratories Incorporated Method preparing amino acid-derived diaminopropanols
CA2461212C (en) 2001-09-27 2010-08-17 Kyorin Pharmaceutical Co., Ltd. Diaryl sulfide derivatives, salts thereof and immunosuppressive agents using the same
WO2004026817A1 (ja) 2002-09-19 2004-04-01 Kyorin Pharmaceutical Co., Ltd. アミノアルコール誘導体とその付加塩及び免疫抑制剤
EP2172472B1 (en) 2003-02-18 2012-12-26 Kyorin Pharmaceutical Co., Ltd. Aminophosphonic acid derivative, salt thereof and modulator of S1P receptor
EP2511262B1 (en) * 2004-10-12 2017-02-01 Kyorin Pharmaceutical Co., Ltd. Process for producing 2-amino-2-[2-[4-(3-benzyloxy-phenylthio)-2-chlorophenyl[ethyl]-1,3-propanediol hydrochloride
PT1932522E (pt) 2005-10-07 2012-06-26 Kyorin Seiyaku Kk Agente terapêutico para doenças do fígado contendo, como princípio activo, um derivado de 2- amino-1,3-propanodiol
JP5100641B2 (ja) 2006-04-28 2012-12-19 田辺三菱製薬株式会社 ２−アミノブタノール化合物及びその医薬用途

Also Published As

Publication number Publication date
KR20160027993A (ko) 2016-03-10
RU2010143432A (ru) 2012-04-27
CN102046594A (zh) 2011-05-04
CA2718987C (en) 2016-03-08
KR101767019B1 (ko) 2017-08-09
US9493410B2 (en) 2016-11-15
US9920005B2 (en) 2018-03-20
AU2009230269B2 (en) 2013-02-07
MX2010010429A (es) 2010-11-26
TW200944495A (en) 2009-11-01
KR20100127292A (ko) 2010-12-03
AU2009230269A1 (en) 2009-10-01
EP2269982A4 (en) 2014-03-12
CA2718987A1 (en) 2009-10-01
US20110021636A1 (en) 2011-01-27
US20170015624A1 (en) 2017-01-19
EP2269982B1 (en) 2016-05-04
JPWO2009119395A1 (ja) 2011-07-21
JP5344320B2 (ja) 2013-11-20
ES2572893T3 (es) 2016-06-02
RU2482110C2 (ru) 2013-05-20
EP3059226A1 (en) 2016-08-24
WO2009119395A1 (ja) 2009-10-01
EP2269982A1 (en) 2011-01-05
CN106366027A (zh) 2017-02-01
TWI429621B (zh) 2014-03-11

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law
B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.