BRPI0910259A2 - métodos de tratamento de inflamação - Google Patents
métodos de tratamento de inflamaçãoInfo
- Publication number
- BRPI0910259A2 BRPI0910259A2 BRPI0910259A BRPI0910259A BRPI0910259A2 BR PI0910259 A2 BRPI0910259 A2 BR PI0910259A2 BR PI0910259 A BRPI0910259 A BR PI0910259A BR PI0910259 A BRPI0910259 A BR PI0910259A BR PI0910259 A2 BRPI0910259 A2 BR PI0910259A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment methods
- inflammation treatment
- inflammation
- methods
- treatment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3838108P | 2008-03-20 | 2008-03-20 | |
| US3937108P | 2008-03-25 | 2008-03-25 | |
| US4580708P | 2008-04-17 | 2008-04-17 | |
| US12109508P | 2008-12-09 | 2008-12-09 | |
| PCT/US2009/037887 WO2009117710A2 (en) | 2008-03-20 | 2009-03-20 | Methods of treating inflammation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0910259A2 true BRPI0910259A2 (pt) | 2015-12-01 |
Family
ID=41091567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0910259A BRPI0910259A2 (pt) | 2008-03-20 | 2009-03-20 | métodos de tratamento de inflamação |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20110044988A1 (pt) |
| EP (2) | EP2252318A4 (pt) |
| JP (2) | JP2011526244A (pt) |
| KR (1) | KR20110014141A (pt) |
| CN (2) | CN102088993A (pt) |
| AU (2) | AU2009225389A1 (pt) |
| BR (1) | BRPI0910259A2 (pt) |
| CA (2) | CA2717071A1 (pt) |
| CO (1) | CO6300848A2 (pt) |
| EA (1) | EA201001529A1 (pt) |
| IL (1) | IL207752A0 (pt) |
| MX (1) | MX2010010198A (pt) |
| NZ (1) | NZ588033A (pt) |
| WO (2) | WO2009117710A2 (pt) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102088993A (zh) * | 2008-03-20 | 2011-06-08 | 卡罗勒斯治疗公司 | 炎症的治疗方法 |
| US20110070184A1 (en) * | 2008-03-24 | 2011-03-24 | Carolus Therpeutics, Inc. | Methods and compositions for treating atherosclerosis and related condidtions |
| US20100183598A1 (en) * | 2008-11-12 | 2010-07-22 | Carolus Therapeutics, Inc. | Methods of treating cardiovascular disorders |
| AU2010298249A1 (en) * | 2009-09-23 | 2012-04-19 | Carolus Therapeutics, Inc. | Methods of treating inflammation |
| EP2308485A1 (en) * | 2009-10-06 | 2011-04-13 | Dompé S.p.a. | Sulfonamides for the prevention of diabetes |
| EP2308484A1 (en) | 2009-10-06 | 2011-04-13 | Dompé S.p.a. | Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets |
| WO2012125680A1 (en) | 2011-03-16 | 2012-09-20 | Novartis Ag | Methods of treating vasculitis using an il-17 binding molecule |
| US9133164B2 (en) * | 2011-04-13 | 2015-09-15 | Innov88 Llc | MIF inhibitors and their uses |
| TWI407964B (zh) * | 2011-05-10 | 2013-09-11 | Univ Fu Jen Catholic | 干擾性核糖核酸用於治療或減緩疼痛之用途 |
| EP2723380B1 (en) | 2011-06-24 | 2019-08-21 | Stephen D. Gillies | Light chain immunoglobulin fusion proteins and methods of use thereof |
| US10596233B2 (en) | 2011-06-30 | 2020-03-24 | Dignity Health | Use of pertussis toxin as a therapeutic agent |
| US9801921B2 (en) | 2011-06-30 | 2017-10-31 | Dignity Health | Use of pertussis toxin as a therapeutic agent |
| US9238689B2 (en) | 2011-07-15 | 2016-01-19 | Morpho Sys AG | Antibodies that are cross-reactive for macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT) |
| CN102357249A (zh) * | 2011-10-26 | 2012-02-22 | 广州赫尔氏药物开发有限公司 | 能够抑制耐药性结核杆菌的药物 |
| ES2656292T3 (es) | 2012-05-01 | 2018-02-26 | Translatum Medicus Inc. | Métodos de tratamiento y diagnóstico de enfermedades oculares que causan ceguera |
| US10046002B2 (en) | 2013-08-02 | 2018-08-14 | Syntrix Biosystems Inc. | Method for treating cancer using chemokine antagonists |
| US10561676B2 (en) * | 2013-08-02 | 2020-02-18 | Syntrix Biosystems Inc. | Method for treating cancer using dual antagonists of CXCR1 and CXCR2 |
| WO2015051330A1 (en) | 2013-10-03 | 2015-04-09 | Oregon Health & Science University | RECOMBINANT POLYPEPTIDES COMPRISING MHC CLASS II α1 DOMAINS |
| CN114478773A (zh) * | 2015-01-09 | 2022-05-13 | 阿达尔塔有限公司 | Cxcr4结合分子 |
| TW201718851A (zh) * | 2015-09-18 | 2017-06-01 | 通用醫院公司 | 具有抗化學排斥(anti-fugetactic)性質之經修飾自然殺手細胞及其用途 |
| WO2017106332A1 (en) | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| CN109069426B (zh) * | 2015-12-14 | 2021-10-29 | X4 制药有限公司 | 治疗癌症的方法 |
| CN109152780B (zh) | 2016-03-11 | 2021-10-01 | 阿迪亚生命科学公司 | 用于治疗结晶性关节病症的cxcr-2抑制剂 |
| KR102645432B1 (ko) * | 2016-03-28 | 2024-03-11 | (주)아모레퍼시픽 | 피부 세포 분화 촉진용 조성물 및 피부 세포 분화 촉진 물질의 스크리닝 방법 |
| US11337969B2 (en) | 2016-04-08 | 2022-05-24 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| EP3445402A4 (en) * | 2016-04-21 | 2019-12-11 | The Board Of Regents Of The University Of Texas System | METHOD AND COMPOSITIONS FOR DETECTING ANEURYSMS |
| KR102379464B1 (ko) | 2016-06-20 | 2022-03-29 | 키맵 리미티드 | 항-pd-l1 항체 |
| CN109640988A (zh) | 2016-06-21 | 2019-04-16 | X4 制药有限公司 | Cxcr4抑制剂及其用途 |
| WO2017223243A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
| ES2870920T3 (es) | 2016-06-21 | 2021-10-28 | X4 Pharmaceuticals Inc | Inhibidores de CXCR4 y usos de los mismos |
| US11291641B2 (en) * | 2016-10-03 | 2022-04-05 | The Children's Medical Center Corporation | Prevention and treatment of diabetic nephropathy |
| CN108355133A (zh) * | 2017-01-26 | 2018-08-03 | 中国医学科学院阜外医院 | 靶向cxcr7的药物组合物和方法 |
| US11767564B2 (en) * | 2017-10-27 | 2023-09-26 | Board Of Regents, The University Of Texas System | Use of SDHA as a prognostic marker and therapeutic target in uveal melanoma |
| CN107964045B (zh) * | 2017-12-18 | 2021-04-23 | 南京医科大学 | 一种人鼠嵌合抗CXCR2全分子IgG及其应用 |
| BR112020020930A2 (pt) | 2018-04-11 | 2021-03-02 | Ohio State Innovation Foundation | composição de liberação de fármaco, método para tratar um distúrbio oftalmológico e kit |
| US11679146B2 (en) | 2018-06-05 | 2023-06-20 | Anji Pharmaceuticals Inc. | Compositions and methods for treating pancreatitis |
| EP3802595A1 (en) * | 2018-06-07 | 2021-04-14 | OncoOne Research & Development GmbH | Anti-oxmif/anti-cd3 antibody for cancer treatment |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| WO2020139620A1 (en) * | 2018-12-26 | 2020-07-02 | Colgate-Palmolive Company | Biomarkers of neutrophil deregulation as diagnostic for gingivitis |
| CN110133306B (zh) * | 2019-05-09 | 2023-04-07 | 北京勤邦生物技术有限公司 | 检测西马特罗的酶联免疫试剂盒及其应用 |
| CA3171250A1 (en) | 2020-03-10 | 2021-09-16 | E. Lynne KELLEY | Methods for treating neutropenia |
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| WO2021219495A1 (en) * | 2020-04-28 | 2021-11-04 | Dalcor Pharma Uk Ltd., Leatherhead, Zug Branch | Methods for treating or preventing a viral infection or inhibiting viral replication |
| EP4237002A4 (en) * | 2020-10-28 | 2025-02-12 | University Health Network | METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF |
| WO2022203308A1 (ko) * | 2021-03-22 | 2022-09-29 | 클립스비엔씨 주식회사 | 신규한 재조합 마이코박테리움 스메그마티스 균주 및 이의 용도 |
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| WO2023150294A2 (en) * | 2022-02-04 | 2023-08-10 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods of detecting and treating cerebral aneurysms |
| WO2025171411A1 (en) * | 2024-02-09 | 2025-08-14 | Herophilus, Inc. | Compositions and methods related to modulating macrophage migration inhibitory factor (mif)-cd74 signaling and related treatments for neuroinflammatory conditions |
| CN121714692A (zh) * | 2026-02-26 | 2026-03-24 | 华中科技大学同济医学院附属协和医院 | Cxcl14抑制剂在制备用于预防或治疗患者腹主动脉瘤的药物中的应用 |
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| DE69435303D1 (de) * | 1993-05-17 | 2010-09-02 | Cytokine Pharmasciences Inc | Er behandlung von krankheiten bei denen eine cytok |
| US6645493B1 (en) * | 1993-05-17 | 2003-11-11 | The Picower Institute For Medical Research | Composition containing anti-MIF antibody |
| US20070072861A1 (en) * | 2000-03-27 | 2007-03-29 | Barbara Roniker | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders |
| BR0206986A (pt) * | 2001-01-12 | 2005-11-01 | Cytokine Pharmasciences Inc | Métodos e composições para modular a regulação da resposta a citotóxica do linfócito por fator inibitório de migração de macrófago |
| JP2003226653A (ja) * | 2001-11-30 | 2003-08-12 | Jun Nishihira | 多発性硬化症治療剤 |
| WO2003047622A1 (fr) * | 2001-11-30 | 2003-06-12 | Jun Nishihira | Remedes pour la sclerose en plaques |
| US6656168B2 (en) * | 2001-12-18 | 2003-12-02 | Kimberly-Clark Worldwide, Inc. | Feminine care product with discrete areas of a skin wellness additive |
| WO2003072753A2 (en) * | 2002-02-27 | 2003-09-04 | Emory University | Multimeric binding complexes |
| KR101017732B1 (ko) * | 2002-03-01 | 2011-02-28 | 이뮤노메딕스, 인코오포레이티드 | 내재화 항-ｃｄ74 항체 및 그 이용방법 |
| WO2004049095A2 (en) * | 2002-11-25 | 2004-06-10 | Jallal Messadek | Betaine and salicylic acid compositions |
| TW200418829A (en) * | 2003-02-14 | 2004-10-01 | Avanir Pharmaceutics | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same |
| US20050202010A1 (en) * | 2003-08-29 | 2005-09-15 | Giroir Brett P. | Method of treatment and bioassay involving macrophage migration inhibitory factor (MIF) as cardiac-derived myocardial depressant factor |
| US7897349B2 (en) * | 2003-12-30 | 2011-03-01 | The United States Of America As Represented By The Department Of Veterans Affairs | Macrophage migration inhibitory factor (MIF) as marker for urological inflammatory disease |
| US20060257466A1 (en) * | 2005-04-06 | 2006-11-16 | Kim Perry M | Administration of macrophage targeted formulations of compounds which modulate cholesterol-metabolizing enzymes for treatment of atherosclerosis |
| US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| JPWO2007138961A1 (ja) * | 2006-05-29 | 2009-10-08 | レドックス・バイオサイエンス株式会社 | マクロファージ遊走阻止因子阻害剤 |
| CN102088993A (zh) * | 2008-03-20 | 2011-06-08 | 卡罗勒斯治疗公司 | 炎症的治疗方法 |
| US20110070184A1 (en) * | 2008-03-24 | 2011-03-24 | Carolus Therpeutics, Inc. | Methods and compositions for treating atherosclerosis and related condidtions |
| US20100183598A1 (en) * | 2008-11-12 | 2010-07-22 | Carolus Therapeutics, Inc. | Methods of treating cardiovascular disorders |
| US20110256130A1 (en) * | 2008-12-01 | 2011-10-20 | Joshua Robert Schultz | Methods of treating inflammatory disorders |
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2009
- 2009-03-20 CN CN2009801093284A patent/CN102088993A/zh active Pending
- 2009-03-20 NZ NZ588033A patent/NZ588033A/xx not_active IP Right Cessation
- 2009-03-20 KR KR1020107023480A patent/KR20110014141A/ko not_active Withdrawn
- 2009-03-20 EP EP09721240A patent/EP2252318A4/en not_active Withdrawn
- 2009-03-20 JP JP2011501003A patent/JP2011526244A/ja active Pending
- 2009-03-20 CA CA2717071A patent/CA2717071A1/en not_active Abandoned
- 2009-03-20 EA EA201001529A patent/EA201001529A1/ru unknown
- 2009-03-20 MX MX2010010198A patent/MX2010010198A/es active IP Right Grant
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- 2009-03-20 WO PCT/US2009/037887 patent/WO2009117710A2/en not_active Ceased
- 2009-03-20 CA CA2717365A patent/CA2717365A1/en not_active Abandoned
- 2009-03-20 BR BRPI0910259A patent/BRPI0910259A2/pt not_active IP Right Cessation
- 2009-03-20 AU AU2009225389A patent/AU2009225389A1/en not_active Abandoned
- 2009-03-20 EP EP09722541A patent/EP2254597A4/en not_active Withdrawn
- 2009-03-20 JP JP2011501000A patent/JP2011515416A/ja active Pending
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|---|---|
| WO2009117710A2 (en) | 2009-09-24 |
| CO6300848A2 (es) | 2011-07-21 |
| MX2010010198A (es) | 2010-12-21 |
| JP2011526244A (ja) | 2011-10-06 |
| IL207752A0 (en) | 2010-12-30 |
| WO2009117710A3 (en) | 2010-01-21 |
| WO2009117706A2 (en) | 2009-09-24 |
| CA2717071A1 (en) | 2009-09-24 |
| NZ588033A (en) | 2012-11-30 |
| EP2252318A4 (en) | 2012-04-18 |
| EP2252318A2 (en) | 2010-11-24 |
| CN102046199A (zh) | 2011-05-04 |
| US20110044988A1 (en) | 2011-02-24 |
| CN102088993A (zh) | 2011-06-08 |
| US20110262386A1 (en) | 2011-10-27 |
| CA2717365A1 (en) | 2009-09-24 |
| EA201001529A1 (ru) | 2011-06-30 |
| EP2254597A2 (en) | 2010-12-01 |
| JP2011515416A (ja) | 2011-05-19 |
| AU2009225389A1 (en) | 2009-09-24 |
| KR20110014141A (ko) | 2011-02-10 |
| WO2009117706A3 (en) | 2010-01-21 |
| AU2009225385A1 (en) | 2009-09-24 |
| EP2254597A4 (en) | 2012-04-18 |
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