BRPI0910349A2 - matriz tridimensional de monetita com porosidade estruturada, molde de preparação de matriz tridimensional, método de síntese de uma matriz tridimensional de monetita com porosidade estruturada e uso da matriz tridimensional de monetita com porosidade estruturada - Google Patents

matriz tridimensional de monetita com porosidade estruturada, molde de preparação de matriz tridimensional, método de síntese de uma matriz tridimensional de monetita com porosidade estruturada e uso da matriz tridimensional de monetita com porosidade estruturada

Info

Publication number
BRPI0910349A2
BRPI0910349A2 BRPI0910349A BRPI0910349A BRPI0910349A2 BR PI0910349 A2 BRPI0910349 A2 BR PI0910349A2 BR PI0910349 A BRPI0910349 A BR PI0910349A BR PI0910349 A BRPI0910349 A BR PI0910349A BR PI0910349 A2 BRPI0910349 A2 BR PI0910349A2
Authority
BR
Brazil
Prior art keywords
matrix
dimensional
monetite
structured porosity
dimensional structured
Prior art date
Application number
BRPI0910349A
Other languages
English (en)
Inventor
Carmen Rueda Rodríguez
Del Olmo Basterrechea
Enrique López Cabarcos
Faleh Tamimi Mariño
Jorge Rubio Retama
Julio Font Pérez
María Begoña Castro Feo
María Dolores García Vázquez
Mohammad Hamdan Ali Alkhraisat
Original Assignee
Histocell Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Histocell Sl filed Critical Histocell Sl
Publication of BRPI0910349A2 publication Critical patent/BRPI0910349A2/pt
Publication of BRPI0910349B1 publication Critical patent/BRPI0910349B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3847—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24744—Longitudinal or transverse tubular cavity or cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0910349-0A 2008-07-08 2009-07-08 Biomaterial na forma de um conjunto de partes e método de síntese de uma matriz tridimensional de monetita com porosidade estruturada BRPI0910349B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/ES08/000482 2008-07-08
PCT/ES2008/000482 WO2010004057A1 (es) 2008-07-08 2008-07-08 MATRICES TRIDIMENSIONALES DE MONETITA POROSA ESTRUCTURADA PARA INGENIERIA TISULAR Y REGENERACION OSEA, Y METODO DE PREPARACIόN DE LAS MISMAS
PCT/ES2009/000358 WO2010004066A1 (es) 2008-07-08 2009-07-08 Matrices tridimensionales de monetita porosa estructurada para ingeniería tisular y regeneración ósea, y método de preparación de las mismas

Publications (2)

Publication Number Publication Date
BRPI0910349A2 true BRPI0910349A2 (pt) 2015-10-06
BRPI0910349B1 BRPI0910349B1 (pt) 2019-03-06

Family

ID=41506711

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0910349-0A BRPI0910349B1 (pt) 2008-07-08 2009-07-08 Biomaterial na forma de um conjunto de partes e método de síntese de uma matriz tridimensional de monetita com porosidade estruturada

Country Status (13)

Country Link
US (1) US9320828B2 (pt)
EP (1) EP2298696B1 (pt)
JP (1) JP5759370B2 (pt)
KR (1) KR101629041B1 (pt)
CN (1) CN102089238B (pt)
AU (1) AU2009267935A1 (pt)
BR (1) BRPI0910349B1 (pt)
CA (1) CA2729920C (pt)
ES (1) ES2676070T3 (pt)
MX (1) MX2011000162A (pt)
PT (1) PT2298696T (pt)
RU (1) RU2491960C9 (pt)
WO (2) WO2010004057A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7789646B2 (en) 2007-12-07 2010-09-07 Zimmer Orthopaedic Surgical Products, Inc. Spacer mold and methods therefor
CN102548510B (zh) 2008-10-29 2015-04-01 捷迈骨科手术产品公司 具有可拆卸固定件的间隔件模具
EP2358651A2 (en) 2008-11-12 2011-08-24 Engqvist, Håkan Hydraulic cements, methods and products
JP5871822B2 (ja) 2010-03-10 2016-03-01 オスディーサイン アーベー 組織欠損を補正するためのインプラントおよび方法
EP2394617B1 (de) * 2010-06-10 2013-12-11 MedSkin Solutions Dr. Suwelack AG Schichtförmige perforierte Biomatrices
GB201101219D0 (en) * 2011-01-24 2011-03-09 King S College London Method
US9463046B2 (en) 2011-08-22 2016-10-11 Ossdsign Ab Implants and methods for using such implants to fill holes in bone tissue
US8591645B2 (en) 2011-09-09 2013-11-26 Ossdsign Ab Hydraulic cements with optimized grain size distribution, methods, articles and kits
US20130066327A1 (en) 2011-09-09 2013-03-14 Håkan Engqvist Hydraulic cement compositions with low ph methods, articles and kits
MX2014014656A (es) * 2012-05-30 2015-08-10 Univ New York Dispositivos de reparacion de tejido y andamiajes.
US9913931B2 (en) 2012-12-14 2018-03-13 Ossdsign Ab Cement-forming compositions, monetite cements, implants and methods for correcting bone defects
US9220597B2 (en) 2013-02-12 2015-12-29 Ossdsign Ab Mosaic implants, kits and methods for correcting bone defects
EP2956088A2 (en) 2013-02-12 2015-12-23 OssDsign AB Mosaic implants, kits and methods for correcting bone defects
TWI615136B (zh) * 2013-12-06 2018-02-21 財團法人金屬工業研究發展中心 椎間植入物及其製備方法
WO2016024248A1 (en) 2014-08-14 2016-02-18 Ossdsign Ab Bone implants for correcting bone defects
GB2535487A (en) * 2015-02-17 2016-08-24 Biocomposites Ltd Device to fill a bone void whilst minimising pressurisation
EP3380046B1 (en) 2015-11-24 2021-07-14 OssDsign AB Bone implants and methods for correcting bone defects
CN109219587B (zh) * 2016-05-30 2021-09-14 富士胶片株式会社 磷酸钙成型体的制造方法、磷酸钙成型体及移植用材料
EP3866711B8 (en) 2018-10-16 2024-11-06 OssDsign AB Implants for filling bore holes in bone
GB2609310B (en) 2018-12-21 2023-08-09 Biosapien Inc Drug-eluting surgical articles and related methods
KR102316847B1 (ko) * 2019-09-24 2021-10-26 가톨릭관동대학교산학협력단 연골 재생용 스캐폴드
CN111166539B (zh) * 2020-01-20 2024-08-20 四川大学 一种模块化集成骨再生修复能力测试芯片及其制备方法与应用
EP4208213A1 (en) * 2020-09-01 2023-07-12 Spiber Technologies AB Method for producing macroporous scaffolds composed of silk and calcium phosphate
US12186000B2 (en) 2020-09-04 2025-01-07 DePuy Synthes Products, Inc. Temporary antimicrobial cement spacer, assembly, kit, and method of manufacture

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5531794A (en) 1993-09-13 1996-07-02 Asahi Kogaku Kogyo Kabushiki Kaisha Ceramic device providing an environment for the promotion and formation of new bone
US5741329A (en) 1994-12-21 1998-04-21 Board Of Regents, The University Of Texas System Method of controlling the pH in the vicinity of biodegradable implants
US5866155A (en) 1996-11-20 1999-02-02 Allegheny Health, Education And Research Foundation Methods for using microsphere polymers in bone replacement matrices and composition produced thereby
US6294187B1 (en) * 1999-02-23 2001-09-25 Osteotech, Inc. Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same
US6905516B1 (en) * 1999-05-19 2005-06-14 Ecole Polytechnique Federale De Lausanne (Epfl) Calcium phosphate bone substitute
DE19940717A1 (de) * 1999-08-26 2001-03-01 Gerontocare Gmbh Resorblerbares Knochenersatz- und Knochenaufbaumaterial
CN1378464A (zh) 1999-12-09 2002-11-06 H·C·罗伯特·马泰斯·斯蒂夫腾 用镁盐稳定的透钙磷石水硬性胶凝材料
JP4669932B2 (ja) * 2000-05-02 2011-04-13 学校法人日本大学 生体材料用組成物及びその硬化体
US7709029B2 (en) 2001-01-24 2010-05-04 Ada Foundation Calcium-containing restoration materials
WO2003000480A1 (en) * 2001-06-22 2003-01-03 The Regents Of The University Of Michigan Methods of designing and fabricating molds
JP3934418B2 (ja) * 2001-12-27 2007-06-20 日本特殊陶業株式会社 リン酸カルシウム硬化体並びにリン酸カルシウム多孔体及びその製造方法
JP2003325653A (ja) * 2002-05-09 2003-11-18 Ngk Spark Plug Co Ltd リン酸カルシウム多孔体
JP2004018459A (ja) 2002-06-17 2004-01-22 Pentax Corp リン酸カルシウム―合成樹脂複合体及びその製造方法
DE10323079A1 (de) * 2003-05-22 2004-12-09 Gerber, Thomas, Prof., Dr. Verfahren zur Herstellung von porösen siliziumdioxidhaltigem Hydroxylapatitgranulat mit kontrollierter Morphologie
GB0311846D0 (en) 2003-05-23 2003-06-25 Univ Birmingham High strength and injectable apatitic calcium phosphate cements
JP2005046530A (ja) * 2003-07-31 2005-02-24 National Institute Of Advanced Industrial & Technology 多孔質リン酸カルシウム硬化体、その製造方法及びそれを用いた人工骨及び薬剤徐放体
US6994726B2 (en) * 2004-05-25 2006-02-07 Calcitec, Inc. Dual function prosthetic bone implant and method for preparing the same
CN1891665A (zh) * 2005-07-08 2007-01-10 上海国睿生命科技有限公司 骨修复用β－磷酸三钙多孔陶瓷材料及其制备方法和应用

Also Published As

Publication number Publication date
RU2491960C2 (ru) 2013-09-10
US20110158963A1 (en) 2011-06-30
JP5759370B2 (ja) 2015-08-05
WO2010004066A1 (es) 2010-01-14
KR101629041B1 (ko) 2016-06-09
JP2011529429A (ja) 2011-12-08
AU2009267935A1 (en) 2010-01-14
KR20110061542A (ko) 2011-06-09
RU2491960C9 (ru) 2013-11-10
BRPI0910349B1 (pt) 2019-03-06
CN102089238A (zh) 2011-06-08
CN102089238B (zh) 2014-03-26
MX2011000162A (es) 2011-05-24
ES2676070T3 (es) 2018-07-16
PT2298696T (pt) 2018-06-25
RU2010153515A (ru) 2012-08-20
EP2298696B1 (en) 2018-03-21
CA2729920A1 (en) 2010-01-14
US9320828B2 (en) 2016-04-26
WO2010004066A8 (es) 2011-03-24
EP2298696A1 (en) 2011-03-23
WO2010004057A1 (es) 2010-01-14
EP2298696A4 (en) 2015-08-12
CA2729920C (en) 2013-11-19

Similar Documents

Publication Publication Date Title
BRPI0912323A2 (pt) molde de fundição com cavidade de molde e respectivos método de produção, composição de revestimento incluindo núcleos e uso
BRPI0809990A2 (pt) Pó de paek, em particular para o uso em um metodo para uma manufatura em camadas de um objeto tridimensional, bem como o método para a sua produção
PT2298696T (pt) Matriz tridimensional de monetita com porosidade estruturada, molde de preparação de matriz tridimensional, método de síntese de uma matriz tridimensional de monetita com porosidade estruturada e uso da matriz tridimensional de monetita com porosidade estruturada
EP2409643A4 (en) Human cavity wall three-dimensional measure method, instrument and system
EP2024114A4 (en) SEQUENTIAL FORMING OF MOLDING TOOLS
EP2328546A4 (en) AQUEOUS COSMETIC PREPARATION AND PRODUCTION METHOD THEREOF
PL1896065T3 (pl) Sposób wytwarzania szczepionek
EP2058014A4 (en) ARTIFICIAL BONE ASSOCIATION
BRPI0906461A2 (pt) Composição para o cuidado oral, e, método para aplicar uma composição de cuidado oral na cavidade oral
ZA200711043B (en) Method of preparing microfibrillar polysaccharide
IT1392910B1 (it) Procedimento per la produzione di lipidi da biomassa
EP2292208A4 (en) SKIN PREPARATION FOR EXTERNAL USE
EP2098215A4 (en) TOOTH FILLING MATERIAL, METHOD FOR THE PRODUCTION THEREOF AND DENTAL COMPOSITE MATERIAL
EP2155147A4 (en) ALOE PREPARATION FOR SKIN IMPROVEMENT
FR2960232B1 (fr) Forme de bombage alveolaire
EP2118795A4 (en) METHODS, SYSTEMS, ALGORITHMS AND MEANS FOR DESCRIBING THE POSSIBLE CONFORMATION OF REAL AND THERORETICAL PROTEINS AND THE ASSESSMENT OF REAL AND THERORETICAL PROTEINS WITH REGARD TO FOLDING, TOTAL FORM AND STRUCTURAL MOTIVES
BR112012008202A2 (pt) processo de preparação de uma composição, componentes e uso da composição
BRPI0921576A2 (pt) artigo retroreflexivo tridimensional termoformável e método de fabricação
BRPI0816700A2 (pt) Composição termoplástica, método para produzir uma composição termoplástico, método para produzir um artigo moldado com base na composição termoplástica,artigo moldado, uso de um agente de liberação de molde
BRPI0905885A2 (pt) "processo de preparação de uma composição que contém polímero, composição e uso da composição"
PT2390326E (pt) Processo de produção de colagénio de tipo ii humano
EP2155914A4 (en) IMPROVEMENTS IN THE MANUFACTURE OF IRON ALLOYS
IL197470A0 (en) Method for producing insulin in the form of an oral preparation
DE112007001531A5 (de) Verfahren zur Herstellung enantiomerenreiner Flavanone
DE602007001830D1 (de) Herstellung von Borhydridsalzen

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]

Free format text: O DEPOSITANTE DEVE RESPONDER A EXIGENCIA FORMULADA NESTE PARECER EM ATE 60 (SESSENTA) DIAS, A PARTIR DA DATA DE PUBLICACAO NA RPI, SOB PENA DO ARQUIVAMENTO DO PEDIDO, DE ACORDO COM O ARTIGO 34, INCISO II, DA LPI, POR MEIO DO SERVICO DE CODIGO 206.PUBLIQUE-SE A EXIGENCIA (6.20).

B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C01B 25/32 , A61L 27/12 , A61F 2/02 , A61F 2/28

Ipc: A61L 27/12 (2000.01), A61L 27/56 (2000.01), A61L 2

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/07/2009, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 16A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2840 DE 10-06-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.