BRPI0910513B8 - uso de pelo menos um polipeptídeo, método para a detecção de câncer de mama e leucemia in vitro, e reagente para a detecção de câncer de mama e leucemia - Google Patents

uso de pelo menos um polipeptídeo, método para a detecção de câncer de mama e leucemia in vitro, e reagente para a detecção de câncer de mama e leucemia

Info

Publication number
BRPI0910513B8
BRPI0910513B8 BRPI0910513A BRPI0910513A BRPI0910513B8 BR PI0910513 B8 BRPI0910513 B8 BR PI0910513B8 BR PI0910513 A BRPI0910513 A BR PI0910513A BR PI0910513 A BRPI0910513 A BR PI0910513A BR PI0910513 B8 BRPI0910513 B8 BR PI0910513B8
Authority
BR
Brazil
Prior art keywords
polypeptide
cancer
leukemia
breast cancer
immunity
Prior art date
Application number
BRPI0910513A
Other languages
English (en)
Inventor
Okano Fumiyoshi
Shimizu Masaki
Saito Takanori
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of BRPI0910513A2 publication Critical patent/BRPI0910513A2/pt
Publication of BRPI0910513B1 publication Critical patent/BRPI0910513B1/pt
Publication of BRPI0910513B8 publication Critical patent/BRPI0910513B8/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001129—Molecules with a "CD" designation not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/80—Vaccine for a specifically defined cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/80—Vaccine for a specifically defined cancer
    • A61K2039/804—Blood cells [leukemia, lymphoma]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/80—Vaccine for a specifically defined cancer
    • A61K2039/812—Breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

usos de pelo menos um polipeptídeo, usos de pelo menos um vetor recombinante, célula apresentadora de antígeno isolada, célula t isolada, método para a indução de imunidade, métodos para a detecção de câncer e reagente para a detecção de câncer. um agente indutor de imunidade que compreende como ingrediente(s) eficaz(es) pelo menos um polipeptídeo selecionado a partir dos polipeptídeos a seguir, o(s) polipeptídeo(s) que possui(em) atividades/atividade indutora de imunidade, ou que possui(em) como ingrediente(s) eficaz(es) um vetor(es) recombinante(s) que compreende polinucleotídeo(s) que codificam o(s) polipeptídeo(s) e os que é/são capazes de expressar o(s) polipeptídeo(s) in vivo podem ser usados para terapia e/ou profilaxia de câncer: (a) um polipeptídeo que consiste, essencialmente, em pelo menos 7 aminoácidos consecutivos em qualquer uma das sequências de aminoácidos de números ímpares dentre as seq id n°s: 3 a 95 da listagem de sequência; (b) um polipeptídeo que apresenta identidade de sequência de pelo menos 90% com o polipeptídeo (a) que consiste, essencialmente, em pelo menos 7 aminoácidos; e (c) um polipeptídeo que compreende o polipeptídeo (a) ou (b) como uma sequência parcial do mesmo. ademais, já que os polipeptídeo(s) acima reagem com os anticorpos que existe especificamente no soro de um paciente com câncer, é possível detectar o câncer em um ser vivo através da medição dos anticorpos em uma amostra.
BRPI0910513A 2008-07-10 2009-07-10 uso de pelo menos um polipeptídeo, método para a detecção de câncer de mama e leucemia in vitro, e reagente para a detecção de câncer de mama e leucemia BRPI0910513B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008-180548 2008-07-10
JP2008180548 2008-07-10
PCT/JP2009/062574 WO2010005069A1 (ja) 2008-07-10 2009-07-10 免疫誘導剤及び癌の検出方法

Publications (3)

Publication Number Publication Date
BRPI0910513A2 BRPI0910513A2 (pt) 2015-09-29
BRPI0910513B1 BRPI0910513B1 (pt) 2020-06-16
BRPI0910513B8 true BRPI0910513B8 (pt) 2021-05-25

Family

ID=41507179

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0910513A BRPI0910513B8 (pt) 2008-07-10 2009-07-10 uso de pelo menos um polipeptídeo, método para a detecção de câncer de mama e leucemia in vitro, e reagente para a detecção de câncer de mama e leucemia

Country Status (16)

Country Link
US (1) US8901082B2 (pt)
EP (1) EP2319533B1 (pt)
JP (1) JP5703562B2 (pt)
KR (1) KR101323192B1 (pt)
CN (1) CN102089001B (pt)
AU (1) AU2009270182B2 (pt)
BR (1) BRPI0910513B8 (pt)
CA (1) CA2730088C (pt)
DK (1) DK2319533T3 (pt)
ES (1) ES2633468T3 (pt)
HU (1) HUE035804T2 (pt)
MX (1) MX2011000116A (pt)
PL (1) PL2319533T3 (pt)
PT (1) PT2319533T (pt)
RU (1) RU2519675C2 (pt)
WO (1) WO2010005069A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2305300E (pt) 2008-07-10 2016-06-16 Toray Industries Composição farmacêutica para o tratamento e prevenção do cancro
US8430043B2 (en) 2010-10-28 2013-04-30 Columbia Insurance Company Methods and devices for controlling a tufting machine for forming tufted carpet
GB201520565D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
JP7087387B2 (ja) 2016-03-28 2022-06-21 東レ株式会社 免疫誘導剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU640397B2 (en) * 1989-08-25 1993-08-26 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Dog-mouse heterohybridoma and gene fragment coding for constant region of canine immunoglobulin
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
WO2001077332A2 (en) * 2000-04-07 2001-10-18 Heska Corporation Compositions and methods related to canine igg and canine il-13 receptors
RU2311920C2 (ru) * 2000-09-20 2007-12-10 Корикса Корпорейшн Композиции и способы для лечения и диагностики рака легких
US7261890B2 (en) * 2001-12-21 2007-08-28 Idexx Laboratories, Inc. Methods for using canine immunoglobulin variable domains and caninized antibodies
WO2004024750A2 (en) * 2002-09-13 2004-03-25 Dyax Corporation Cd44-binding ligands
AU2003298786A1 (en) * 2002-11-26 2004-06-18 Protein Design Labs, Inc. Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
JPWO2005083074A1 (ja) 2004-03-01 2007-11-22 有限会社金沢大学ティ・エル・オー 腫瘍抗原ペプチド
JP4547197B2 (ja) * 2004-06-30 2010-09-22 公正 安元 癌特異的腫瘍抗原
WO2008034076A2 (en) * 2006-09-15 2008-03-20 The Johns Hopkins University Cyclophosphamide in combination with immune therapeutics
WO2008141197A1 (en) * 2007-05-10 2008-11-20 Sea Lane Biotechnologies, Llc Chain reaction creating oligomers from repeat units of binding molecules

Also Published As

Publication number Publication date
WO2010005069A1 (ja) 2010-01-14
EP2319533A4 (en) 2012-11-07
DK2319533T3 (en) 2017-07-17
KR101323192B1 (ko) 2013-10-30
RU2011104704A (ru) 2012-08-20
PL2319533T3 (pl) 2017-10-31
US8901082B2 (en) 2014-12-02
HUE035804T2 (en) 2018-05-28
ES2633468T3 (es) 2017-09-21
BRPI0910513B1 (pt) 2020-06-16
BRPI0910513A2 (pt) 2015-09-29
CN102089001B (zh) 2015-01-14
EP2319533B1 (en) 2017-05-10
CN102089001A (zh) 2011-06-08
AU2009270182A1 (en) 2010-01-14
EP2319533A1 (en) 2011-05-11
US20110130343A1 (en) 2011-06-02
MX2011000116A (es) 2011-02-25
CA2730088C (en) 2020-04-14
JPWO2010005069A1 (ja) 2012-01-05
JP5703562B2 (ja) 2015-04-22
PT2319533T (pt) 2017-07-20
RU2519675C2 (ru) 2014-06-20
AU2009270182B2 (en) 2015-01-22
CA2730088A1 (en) 2010-01-14
KR20110019766A (ko) 2011-02-28

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