BRPI0912499A2 - tri-calcium phosphate and hydroxyapatite biomaterial production process - Google Patents
tri-calcium phosphate and hydroxyapatite biomaterial production process Download PDFInfo
- Publication number
- BRPI0912499A2 BRPI0912499A2 BRPI0912499A BRPI0912499A2 BR PI0912499 A2 BRPI0912499 A2 BR PI0912499A2 BR PI0912499 A BRPI0912499 A BR PI0912499A BR PI0912499 A2 BRPI0912499 A2 BR PI0912499A2
- Authority
- BR
- Brazil
- Prior art keywords
- tri
- calcium phosphate
- hydroxyapatite
- production process
- paste
- Prior art date
Links
- 239000001506 calcium phosphate Substances 0.000 title abstract 4
- 229910000391 tricalcium phosphate Inorganic materials 0.000 title abstract 4
- 229940078499 tricalcium phosphate Drugs 0.000 title abstract 4
- 239000012620 biological material Substances 0.000 title abstract 3
- 229910052588 hydroxylapatite Inorganic materials 0.000 title abstract 3
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 title abstract 3
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 title abstract 3
- 235000019731 tricalcium phosphate Nutrition 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229920002472 Starch Polymers 0.000 abstract 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910010293 ceramic material Inorganic materials 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- -1 polypropylene forms Polymers 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000012254 powdered material Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Landscapes
- Materials For Medical Uses (AREA)
Abstract
PROCESSO DE PRODUçãO DE BIOMATERIAL DE TRI-CáLCIO FOSFATO E HIDROXIAPATITA. RESUMO Patente de biomaterial de tri-cálcio fosfato e hidroxiapatita, para uso em cirurgias que necessitem de substituto ásseo como enxertia ou outras indicações. Misturamos os materiais em forma de pó, com a seguinte composição: 70% de tri-cálcio fosfato Ca~3~ (PO~4~)~2~; 30% de hidroxiapatita, Ca~10~(PO~4~)~6~(OH)2. Um composto de 90% deste material e 10% de Amido em pó é formado. Adicionamos dois mililitros de peróxido de hidrogênio [H~2~O~2~] com uma concentraçao de 10% para cada grama deste composto. Esta massa em forma de pasta cerâmica é homogeneizada e em seguida colocada em formas de polipropileno e depois em uma estufa. O material cerâmico seco retirado é colocado em suportes de alumina, sendo entao sinterizado a 1200<198>C, seguindo uma rampa de aquecimento. Podemos moldar o material em vários tamanhos e formas.TRI-CALCIUM PHOSPHATE AND HYDROXIAPATITA BIOMATERIAL PRODUCTION PROCESS. SUMMARY Patent for tri-calcium phosphate and hydroxyapatite biomaterial for use in surgeries requiring bone replacement as grafting or other indications. We mix the powdered materials with the following composition: 70% Ca-3 ~ (PO-4 ~) ~ 2-tricalcium phosphate; 30% hydroxyapatite, Ca ~ 10 ~ (PO ~ 4 ~) ~ 6 ~ (OH) 2. A compound of 90% of this material and 10% of starch powder is formed. We add two milliliters of hydrogen peroxide [H ~ 2 ~ O ~ 2 ~] with a concentration of 10% for each gram of this compound. This paste-like paste is homogenized and then placed in polypropylene forms and then in a greenhouse. The dried out ceramic material is placed on alumina supports and then sintered at 1200Â ° C following a heating ramp. We can shape the material into various sizes and shapes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0912499 BRPI0912499A2 (en) | 2009-11-27 | 2009-11-27 | tri-calcium phosphate and hydroxyapatite biomaterial production process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0912499 BRPI0912499A2 (en) | 2009-11-27 | 2009-11-27 | tri-calcium phosphate and hydroxyapatite biomaterial production process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0912499A2 true BRPI0912499A2 (en) | 2012-02-28 |
Family
ID=45699812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0912499 BRPI0912499A2 (en) | 2009-11-27 | 2009-11-27 | tri-calcium phosphate and hydroxyapatite biomaterial production process |
Country Status (1)
| Country | Link |
|---|---|
| BR (1) | BRPI0912499A2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014075156A1 (en) * | 2012-11-14 | 2014-05-22 | Universidade Estadual De Campinas - Unicamp | Process for producing porous inserts made of hydroxyapatite and tricalcium phosphate, inserts produced by same and use thereof |
-
2009
- 2009-11-27 BR BRPI0912499 patent/BRPI0912499A2/en not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014075156A1 (en) * | 2012-11-14 | 2014-05-22 | Universidade Estadual De Campinas - Unicamp | Process for producing porous inserts made of hydroxyapatite and tricalcium phosphate, inserts produced by same and use thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B03A | Publication of an application: publication of a patent application or of a certificate of addition of invention | ||
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B04C | Request for examination: reinstatement - article 33, solely paragraph, of industrial property law | ||
| B04Z | Request for examination: publication cancelled |
Free format text: ANULADO POR CONTER FALHA NO PARECER DE DESARQUIVAMENTO. |
|
| B04C | Request for examination: reinstatement - article 33, solely paragraph, of industrial property law | ||
| B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
| B07A | Technical examination (opinion): publication of technical examination (opinion) | ||
| B09B | Decision: refusal | ||
| B09B | Decision: refusal |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |