BRPI0914068A2 - processo de resolução de n-[2-(1,6,7,8-tetra-hidro-2h-indeno[5, 4- b]furano-8-il)]etilamina e ramelteon - Google Patents

processo de resolução de n-[2-(1,6,7,8-tetra-hidro-2h-indeno[5, 4- b]furano-8-il)]etilamina e ramelteon

Info

Publication number
BRPI0914068A2
BRPI0914068A2 BRPI0914068A BRPI0914068A BRPI0914068A2 BR PI0914068 A2 BRPI0914068 A2 BR PI0914068A2 BR PI0914068 A BRPI0914068 A BR PI0914068A BR PI0914068 A BRPI0914068 A BR PI0914068A BR PI0914068 A2 BRPI0914068 A2 BR PI0914068A2
Authority
BR
Brazil
Prior art keywords
ramelteon
indeno
ethylamine
furan
tetrahydro
Prior art date
Application number
BRPI0914068A
Other languages
English (en)
Inventor
Amol Bandal
Atul Parab
Bhupesh Aher
Chandrasekhar Sinha
Manjunath Narayan Bhanu
Original Assignee
Watson Pharma Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Watson Pharma Private Ltd filed Critical Watson Pharma Private Ltd
Publication of BRPI0914068A2 publication Critical patent/BRPI0914068A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0914068A 2008-11-14 2009-11-12 processo de resolução de n-[2-(1,6,7,8-tetra-hidro-2h-indeno[5, 4- b]furano-8-il)]etilamina e ramelteon BRPI0914068A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2403MU2008 2008-11-14
PCT/IB2009/055038 WO2010055481A1 (en) 2008-11-14 2009-11-12 Process for the preparation of ramelteon

Publications (1)

Publication Number Publication Date
BRPI0914068A2 true BRPI0914068A2 (pt) 2015-10-13

Family

ID=42169683

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0914068A BRPI0914068A2 (pt) 2008-11-14 2009-11-12 processo de resolução de n-[2-(1,6,7,8-tetra-hidro-2h-indeno[5, 4- b]furano-8-il)]etilamina e ramelteon

Country Status (5)

Country Link
US (1) US20110207949A1 (pt)
EP (1) EP2344468A4 (pt)
AU (1) AU2009315280A1 (pt)
BR (1) BRPI0914068A2 (pt)
WO (1) WO2010055481A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012035303A2 (en) 2010-09-17 2012-03-22 Cipla Limited Et Al A novel process for synthesis of ramelteon, and key intermediates for the synthesis of ramelteon
CN102924410A (zh) * 2012-10-29 2013-02-13 华润赛科药业有限责任公司 一种雷美替胺的制备方法及其中间体
CN104119307B (zh) * 2013-04-24 2016-08-17 辰欣药业股份有限公司 (s)-2-(1,6,7,8-四氢-2h-茚并[5,4-b]呋喃-8-基)乙胺的制备方法
CN104327021A (zh) * 2014-11-24 2015-02-04 苏州乔纳森新材料科技有限公司 一种雷美替胺中间体的拆分方法
CN104447645A (zh) * 2014-11-24 2015-03-25 苏州乔纳森新材料科技有限公司 雷美替胺中间体的拆分方法
CN104529959A (zh) * 2015-01-27 2015-04-22 江苏嘉逸医药有限公司 雷美替胺的合成方法
CN107325066A (zh) * 2017-05-23 2017-11-07 万特制药(海南)有限公司 雷美替胺中间体的拆分方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2074932A1 (en) * 1991-08-23 1993-02-24 Hiroyuki Nohira Optical resolution of (+)-2-(4-isobutylphenyl) propionic acid
ES2175350T5 (es) * 1996-03-08 2008-12-16 Takeda Pharmaceutical Company Limited Compuestos triciclicos que tienen afinidad de union a receptores de melatonina, su produccion y uso.
US6034239A (en) * 1996-03-08 2000-03-07 Takeda Chemical Industries, Ltd. Tricyclic compounds, their production and use
EP1100508B8 (en) * 1998-06-09 2004-01-07 Takeda Chemical Industries, Ltd. Pharmaceutical combination comprising a tricyclic compound and at least one of zolpidem, zopiclone and brotizolam for treating or preventing sleep disorders
WO2008062468A2 (en) * 2006-10-26 2008-05-29 Cadila Healthcare Limited Process for the preparation of optically pure indeno [5,4-b] furan derivatives
US8138174B2 (en) * 2007-01-10 2012-03-20 Solvay Pharmaceuticals B.V. Compounds with a combination of cannabinoid CB1 antagonism and serotonin reuptake inhibition
US20080242877A1 (en) * 2007-02-26 2008-10-02 Vinod Kumar Kansal Intermediates and processes for the synthesis of Ramelteon

Also Published As

Publication number Publication date
EP2344468A1 (en) 2011-07-20
US20110207949A1 (en) 2011-08-25
EP2344468A4 (en) 2012-08-01
AU2009315280A1 (en) 2010-05-20
WO2010055481A1 (en) 2010-05-20

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.