BRPI0914153A2 - Métodos de síntese de morfinanos - Google Patents

Métodos de síntese de morfinanos

Info

Publication number
BRPI0914153A2
BRPI0914153A2 BRPI0914153-7A BRPI0914153A BRPI0914153A2 BR PI0914153 A2 BRPI0914153 A2 BR PI0914153A2 BR PI0914153 A BRPI0914153 A BR PI0914153A BR PI0914153 A2 BRPI0914153 A2 BR PI0914153A2
Authority
BR
Brazil
Prior art keywords
synthesis methods
morphinan
morphinan synthesis
methods
synthesis
Prior art date
Application number
BRPI0914153-7A
Other languages
English (en)
Inventor
John A Lawson
Original Assignee
Phoenix Pharmalabs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phoenix Pharmalabs Inc filed Critical Phoenix Pharmalabs Inc
Publication of BRPI0914153A2 publication Critical patent/BRPI0914153A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C07D489/04—Salts; Organic complexes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0914153-7A 2008-06-20 2009-05-08 Métodos de síntese de morfinanos BRPI0914153A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/143,608 US8691989B2 (en) 2008-06-20 2008-06-20 Methods of synthesis of morphinans
PCT/US2009/002875 WO2009154673A1 (en) 2008-06-20 2009-05-08 Methods of synthesis of morphinans

Publications (1)

Publication Number Publication Date
BRPI0914153A2 true BRPI0914153A2 (pt) 2015-08-04

Family

ID=40943675

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0914153-7A BRPI0914153A2 (pt) 2008-06-20 2009-05-08 Métodos de síntese de morfinanos

Country Status (9)

Country Link
US (1) US8691989B2 (pt)
EP (1) EP2303892A1 (pt)
JP (1) JP2011524902A (pt)
CN (1) CN102089311A (pt)
AU (1) AU2009260875B2 (pt)
BR (1) BRPI0914153A2 (pt)
CA (1) CA2727837A1 (pt)
IL (1) IL210106A0 (pt)
WO (1) WO2009154673A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2806620A1 (en) 2010-08-04 2012-02-09 Mallinckrodt Llc Tandem process for preparing n-alkyl morphinans
US8987293B2 (en) 2010-12-23 2015-03-24 Phoenix Pharmalabs, Inc. Morphinans useful as analgesics
WO2019100057A1 (en) * 2017-11-20 2019-05-23 Phoenix Pharmalabs, Inc. Use of morphinans for treating cocaine addiction, pruritis, and seizure disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342824A (en) * 1964-12-07 1967-09-19 Lilly Co Eli Normorphines
DE2254298A1 (de) 1972-11-06 1974-05-16 Boehringer Sohn Ingelheim Neue (heteroarylmethyl)-normorphine, deren saeureadditionssalze, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
US4218454A (en) * 1977-07-08 1980-08-19 Sri International N-αMethylcyclopropylmethyl derivatives of normorphine and noroodeine, and analgesic compositions and methods employing the normorphine derivatives
US4749706A (en) * 1986-03-24 1988-06-07 Sri International Orally active nonaddicting analgesics
US5366979A (en) * 1990-06-07 1994-11-22 Pharmaco Development Partners Orally active nonaddicting analgesics
US7935820B2 (en) * 2007-06-29 2011-05-03 Brock University Methods for N-demethylation of morphine and tropane alkaloids

Also Published As

Publication number Publication date
US20090318699A1 (en) 2009-12-24
CA2727837A1 (en) 2009-12-23
EP2303892A1 (en) 2011-04-06
JP2011524902A (ja) 2011-09-08
WO2009154673A1 (en) 2009-12-23
US8691989B2 (en) 2014-04-08
AU2009260875A1 (en) 2009-12-23
AU2009260875B2 (en) 2014-07-10
IL210106A0 (en) 2011-02-28
CN102089311A (zh) 2011-06-08

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.