BRPI0915086B8 - detecção do uso de canabis - Google Patents

detecção do uso de canabis

Info

Publication number
BRPI0915086B8
BRPI0915086B8 BRPI0915086A BRPI0915086A BRPI0915086B8 BR PI0915086 B8 BRPI0915086 B8 BR PI0915086B8 BR PI0915086 A BRPI0915086 A BR PI0915086A BR PI0915086 A BRPI0915086 A BR PI0915086A BR PI0915086 B8 BRPI0915086 B8 BR PI0915086B8
Authority
BR
Brazil
Prior art keywords
cannabis use
binding partner
thc
use detection
immunoassay
Prior art date
Application number
BRPI0915086A
Other languages
English (en)
Inventor
Timo Pulli
Hans SÖDERLUND
Kristiina Takkinen
Original Assignee
Teknologian Tutkimuskeskus Vtt Oy
Valtion Teknillinen Tutkimuskeskus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teknologian Tutkimuskeskus Vtt Oy, Valtion Teknillinen Tutkimuskeskus filed Critical Teknologian Tutkimuskeskus Vtt Oy
Publication of BRPI0915086A2 publication Critical patent/BRPI0915086A2/pt
Publication of BRPI0915086B1 publication Critical patent/BRPI0915086B1/pt
Publication of BRPI0915086B8 publication Critical patent/BRPI0915086B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/16—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Anesthesiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Geophysics And Detection Of Objects (AREA)

Abstract

detecção do uso de canabis. é descrito um parceiro de ligação, especialmente um fragmento de anticorpo que reconhece especificamente um complexo imune antígeno-anticorpo entre anti-thc e thc (tetrahidrocanabinol). o parceiro de ligação facilita um imunoensaio homogêneo não competitivo para a detecção do uso de canabis. e também descrito um kit de teste compreendendo o parceiro de ligação. preferivelmente, o imunoensaio é aplicado para teste em estrada de salina de motoristas suspeitos.
BRPI0915086A 2008-06-12 2009-06-05 detecção do uso de canabis BRPI0915086B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FI20085579 2008-06-12
FI20085579A FI20085579A0 (fi) 2008-06-12 2008-06-12 Kannabiskäytön toteaminen
PCT/FI2009/050481 WO2009150295A1 (en) 2008-06-12 2009-06-05 Detection of cannabis use

Publications (3)

Publication Number Publication Date
BRPI0915086A2 BRPI0915086A2 (pt) 2016-07-26
BRPI0915086B1 BRPI0915086B1 (pt) 2020-05-12
BRPI0915086B8 true BRPI0915086B8 (pt) 2021-07-27

Family

ID=39589343

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0915086A BRPI0915086B8 (pt) 2008-06-12 2009-06-05 detecção do uso de canabis

Country Status (20)

Country Link
US (1) US8518653B2 (pt)
EP (1) EP2297585B1 (pt)
JP (1) JP5675597B2 (pt)
CN (1) CN102057277B (pt)
AU (1) AU2009256482B2 (pt)
BR (1) BRPI0915086B8 (pt)
CA (1) CA2724660C (pt)
CY (1) CY1117631T1 (pt)
DK (1) DK2297585T3 (pt)
EA (1) EA019664B1 (pt)
ES (1) ES2566501T3 (pt)
FI (1) FI20085579A0 (pt)
HR (1) HRP20160237T1 (pt)
HU (1) HUE028677T2 (pt)
MX (1) MX2010013692A (pt)
NZ (1) NZ589300A (pt)
PL (1) PL2297585T3 (pt)
SI (1) SI2297585T1 (pt)
WO (1) WO2009150295A1 (pt)
ZA (1) ZA201008491B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11062795B2 (en) 2007-03-02 2021-07-13 Enigami Systems, Inc. Healthcare data system
EP2673635A4 (en) 2011-02-07 2015-08-12 Neotope Biosciences Ltd IMMUNOTHERAPY THROUGH APOE
EP2759551B1 (en) * 2011-09-21 2019-05-22 Fujirebio Inc. Antibodies binding to an affinity complex comprising 25oh vitamin d2 or d3 and an antibody thereto
US9970950B1 (en) 2014-03-09 2018-05-15 Hound Labs, Inc. Method and apparatus for detecting acute use of target substance(s)
JP6673895B2 (ja) 2014-03-21 2020-03-25 エスティー アンド ティー インターナショナル，インコーポレイティド アサ属抽出方法及び組成物
MA39708A (fr) 2014-03-27 2021-03-31 Bird Rock Bio Inc Anticorps qui se lient au récepteur cannabinoïde 1 (cb1) humain
US10319475B1 (en) 2014-06-13 2019-06-11 Enigami Systems, Inc. Method and apparatus for determining relationships between medications and symptoms
US9726684B1 (en) 2015-01-18 2017-08-08 Hound Labs, Inc. Compositions for target substance detection and measurement
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
BR112018006633A2 (pt) 2015-09-30 2018-10-23 Bird Rock Bio, Inc. anticorpos que se ligam ao receptor canabinóide 1 (cb1) humano
US9823259B1 (en) 2016-04-08 2017-11-21 Walter Nichols Detection device for cannabinoid use
US9933445B1 (en) 2016-05-16 2018-04-03 Hound Labs, Inc. System and method for target substance identification
US9921234B1 (en) 2016-06-17 2018-03-20 Hound Labs, Inc. Compositions and methods for detection of target constituent in exhaled breath
US11026596B1 (en) 2017-05-19 2021-06-08 Hound Labs, Inc. Detection and measurement of target substance in exhaled breath
US11187711B1 (en) 2017-09-11 2021-11-30 Hound Labs, Inc. Analyte detection from breath samples
EP3724657A4 (en) * 2017-12-15 2021-12-29 Bomi, Llc Anti-cannabidiol antibody and uses thereof
US10897925B2 (en) 2018-07-27 2021-01-26 Joseph Pandolfino Articles and formulations for smoking products and vaporizers
US20200035118A1 (en) 2018-07-27 2020-01-30 Joseph Pandolfino Methods and products to facilitate smokers switching to a tobacco heating product or e-cigarettes
US11426097B1 (en) 2018-10-17 2022-08-30 Hound Labs, Inc. Rotary valve assemblies and methods of use for breath sample cartridge systems
US20200245899A1 (en) 2019-01-31 2020-08-06 Hound Labs, Inc. Mechanical Breath Collection Device
US11977086B2 (en) 2019-03-21 2024-05-07 Hound Labs, Inc. Biomarker detection from breath samples
US11933731B1 (en) 2020-05-13 2024-03-19 Hound Labs, Inc. Systems and methods using Surface-Enhanced Raman Spectroscopy for detecting tetrahydrocannabinol
US12392769B1 (en) 2021-01-12 2025-08-19 Hound Labs, Inc. Ambient contamination in breath analyte detection and measurement
CA3239050A1 (en) * 2021-11-24 2023-06-01 Alexei Leonidovich Beresnev System and method for determining intoxicant impairment

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996345A (en) * 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
DE3433652A1 (de) * 1984-09-13 1986-03-20 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemisches messverfahren fuer haptene und proteine
WO1987007147A1 (en) * 1986-05-28 1987-12-03 Murex Corporation Method for producing monoclonal antibodies to an immunogenic antibody-antigen conjunction
US5223441A (en) * 1986-10-09 1993-06-29 Syntex (U.S.A.) Inc. Receptors for immune complexes
CA2072758A1 (en) * 1990-09-14 1992-03-15 Kenneth Francis Buechler Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
FI20022048A0 (fi) * 2002-11-18 2002-11-18 Valtion Teknillinen Ei-kompetetiivinen immunomääritys pienille analyyteille
US7960518B2 (en) * 2006-06-06 2011-06-14 Crucell Holland B.V. Human binding molecules having killing activity against enterococci and uses thereof

Also Published As

Publication number Publication date
HUE028677T2 (en) 2016-12-28
HRP20160237T1 (hr) 2016-04-22
JP5675597B2 (ja) 2015-02-25
EA201071435A1 (ru) 2011-08-30
US20110086364A1 (en) 2011-04-14
ES2566501T3 (es) 2016-04-13
CN102057277A (zh) 2011-05-11
EP2297585A1 (en) 2011-03-23
SI2297585T1 (sl) 2016-06-30
PL2297585T3 (pl) 2016-09-30
BRPI0915086B1 (pt) 2020-05-12
CA2724660A1 (en) 2009-12-17
CN102057277B (zh) 2014-12-24
BRPI0915086A2 (pt) 2016-07-26
JP2011524013A (ja) 2011-08-25
DK2297585T3 (en) 2016-03-29
FI20085579A0 (fi) 2008-06-12
ZA201008491B (en) 2011-08-31
US8518653B2 (en) 2013-08-27
EP2297585A4 (en) 2012-05-02
EA019664B1 (ru) 2014-05-30
CA2724660C (en) 2019-07-09
WO2009150295A1 (en) 2009-12-17
AU2009256482B2 (en) 2014-11-13
EP2297585B1 (en) 2016-03-02
AU2009256482A1 (en) 2009-12-17
NZ589300A (en) 2011-11-25
MX2010013692A (es) 2011-03-04
CY1117631T1 (el) 2017-04-26

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Legal Events

Date Code Title Description
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25D Requested change of name of applicant approved

Owner name: TEKNOLOGIAN TUTKIMUSKESKUS VTT (FI)

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 12/05/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/06/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B25A Requested transfer of rights approved

Owner name: TEKNOLOGIAN TUTKIMUSKESKUS VTT OY (FI)