BRPI0916535A2 - nanoemulsão de docetaxel de óleo em água estável injectável. - Google Patents

nanoemulsão de docetaxel de óleo em água estável injectável.

Info

Publication number: BRPI0916535A2
Authority: BR; Brazil
Prior art keywords: oil; injectable water; stable injectable; nanoemulsion; docetaxel
Prior art date: 2008-07-23

Application number

BRPI0916535A

Other languages

English (en)

Inventor

Gautam Vinod Daftary

Mangesh Manikrao Kulkarni

Srikanth Annappa Pai

Original Assignee

Bharat Serums & Vaccines Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-23

Filing date

2009-07-22

Publication date

2015-11-10

2009-07-22 Application filed by Bharat Serums & Vaccines Ltd filed Critical Bharat Serums & Vaccines Ltd

2015-11-10 Publication of BRPI0916535A2 publication Critical patent/BRPI0916535A2/pt

Links

ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 title 1
229960003668 docetaxel Drugs 0.000 title 1
239000007908 nanoemulsion Substances 0.000 title 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Dispersion Chemistry (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BRPI0916535A 2008-07-23 2009-07-22 nanoemulsão de docetaxel de óleo em água estável injectável. BRPI0916535A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IN1565MU2008		2008-07-23
PCT/IN2009/000416 WO2010018596A2 (en)	2008-07-23	2009-07-22	Stable injectable oil-in-water docetaxel nanoemulsion

Publications (1)

Publication Number	Publication Date
BRPI0916535A2 true BRPI0916535A2 (pt)	2015-11-10

Family

ID=41527728

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0916535A BRPI0916535A2 (pt)	2008-07-23	2009-07-22	nanoemulsão de docetaxel de óleo em água estável injectável.

Country Status (13)

Country	Link
US (1)	US20110275705A1 (pt)
EP (1)	EP2317978A2 (pt)
JP (1)	JP5635504B2 (pt)
KR (1)	KR20110036075A (pt)
CN (1)	CN102105134B (pt)
AU (1)	AU2009280803B2 (pt)
BR (1)	BRPI0916535A2 (pt)
CA (1)	CA2731353A1 (pt)
EA (1)	EA201100069A1 (pt)
MX (1)	MX2011000795A (pt)
NZ (1)	NZ590730A (pt)
WO (1)	WO2010018596A2 (pt)
ZA (1)	ZA201100465B (pt)

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CA2510196C (en)	2002-12-20	2014-04-01	Generipharm, Inc.	Intracutaneous injection
TWI438009B (zh) *	2010-02-19	2014-05-21	Teikoku Pharma Usa Inc	紫杉烷前－乳劑調配物及其製造與使用之方法
US10842770B2 (en)	2010-05-03	2020-11-24	Teikoku Pharma Usa, Inc.	Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
CN102309445B (zh) *	2010-07-06	2013-03-27	上海现代药物制剂工程研究中心有限公司	多西他赛静脉注射组合物及其制备方法
WO2012012460A1 (en)	2010-07-19	2012-01-26	Xeris Pharmaceuticals, Inc.	Stable glucagon formulations for the treatment of hypoglycemia
WO2012068105A2 (en)	2010-11-15	2012-05-24	Archer Daniels Midland Company	Compositions and uses thereof in converting contaminants
WO2012075534A1 (en)	2010-12-10	2012-06-14	Ns Technologies Pty Ltd	Methods for forming miniemulsions and use thereof for delivering bioactive agents
AU2012225268B2 (en)	2011-03-10	2016-10-20	Xeris Pharmaceuticals, Inc.	Stable formulations for parenteral injection of peptide drugs
CA2835525C (en) *	2011-05-10	2016-03-01	Archer Daniels Midland Company	Dispersants having biobased compounds
WO2012156999A1 (en) *	2011-05-19	2012-11-22	Manu Chaudhary	Ready to use docetaxel formulation
EA027744B1 (ru)	2011-10-31	2017-08-31	Ксерис Фармасьютикалс, Инк.	Лекарственные формы для лечения сахарного диабета
US9125805B2 (en)	2012-06-27	2015-09-08	Xeris Pharmaceuticals, Inc.	Stable formulations for parenteral injection of small molecule drugs
JO3685B1 (ar) *	2012-10-01	2020-08-27	Teikoku Pharma Usa Inc	صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
HK1211203A1 (en) *	2012-10-16	2016-05-20	Inspyr Therapeutics, Inc.	Injectable cancer compositions
US9018162B2 (en)	2013-02-06	2015-04-28	Xeris Pharmaceuticals, Inc.	Methods for rapidly treating severe hypoglycemia
CN103315978B (zh) *	2013-07-12	2014-12-03	上海市第八人民医院	多西紫杉醇干酏剂及其制备方法和应用
WO2015013566A1 (en) *	2013-07-25	2015-01-29	Nemucore Medical Innovations, Inc.	Nanoemulsions of hydrophobic platinum derivative
WO2015106094A1 (en) *	2014-01-10	2015-07-16	Atossa Genetics Inc.	Transpapillary methods and compositions for diagnosing and treating breast conditions
WO2016022831A1 (en)	2014-08-06	2016-02-11	Xeris Pharmaceuticals, Inc.	Syringes, kits, and methods for intracutaneous and/or subcutaneous injection of pastes
CN104626418B (zh) *	2015-01-27	2016-10-05	天津现代职业技术学院	异型橡胶管用无硅脂型脱模剂
CN106176599A (zh) *	2015-05-06	2016-12-07	江苏天士力帝益药业有限公司	一种卡巴他赛脂肪乳注射剂及其制备方法
US9649364B2 (en)	2015-09-25	2017-05-16	Xeris Pharmaceuticals, Inc.	Methods for producing stable therapeutic formulations in aprotic polar solvents
US11590205B2 (en)	2015-09-25	2023-02-28	Xeris Pharmaceuticals, Inc.	Methods for producing stable therapeutic glucagon formulations in aprotic polar solvents
JP7518604B2 (ja) *	2016-06-07	2024-07-18	タルガジェニックス，インコーポレイテッド	タキソイド薬物のナノエマルション組成物、並びに標的癌細胞及び癌幹細胞に対するその使用方法
WO2017214468A1 (en) *	2016-06-09	2017-12-14	Tien Yang Der	Nanodroplet compositions for the efficient delivery of anti-cancer agents
JP7097593B2 (ja) *	2017-03-31	2022-07-08	テクノガード株式会社	薬物を保持した脂肪粒子を含む非水系組成物およびその製造方法
KR20240036128A (ko)	2017-06-02	2024-03-19	엑스에리스 파머수티클스, 인크.	침전 방지 저분자 약물 제제
CN111920782B (zh) *	2019-05-13	2025-11-18	中国医学科学院药物研究所	复合脂质纳米囊组合物及其制备方法和应用
EP4404919A4 (en) *	2021-09-22	2025-08-20	Hdt Bio Corp	DRIED NANOPARTICLE COMPOSITIONS
WO2024206239A1 (en) *	2023-03-24	2024-10-03	Insitu Biologics, Inc.	Sustained release cancer therapeutics formulations

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US5478860A (en)	1993-06-04	1995-12-26	Inex Pharmaceuticals Corp.	Stable microemulsions for hydrophobic compound delivery
GB9715759D0 (en) *	1997-07-26	1997-10-01	Danbiosyst Uk	New emulsion formulations
TW422706B (en) *	1999-07-01	2001-02-21	Wang Iz Rung	An oil-in-water emulsion type of paclitaxel
US20050214378A1 (en) *	2002-06-11	2005-09-29	Ethypharm	Stealth lipid nanocapsules, methods for the preparation thereof and use thereof as a carrier for active principle(s)
US8557861B2 (en) *	2004-09-28	2013-10-15	Mast Therapeutics, Inc.	Low oil emulsion compositions for delivering taxoids and other insoluble drugs
TWI376239B (en) *	2006-02-01	2012-11-11	Andrew Xian Chen	Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof
WO2008058366A1 (en) *	2006-09-28	2008-05-22	Université de Montréal	Oil-in-water emulsions, methods of use thereof, methods of preparation thereof and kits thereof
WO2008042841A2 (en) *	2006-10-02	2008-04-10	Dr. Reddy's Laboratories Limited	Docetaxel compositions
US20080234376A1 (en) *	2007-03-21	2008-09-25	Taiwan Liposome Company (A Taiwan Corporation)	Emulsion composition comprising prostaglandin e1
CN100569294C (zh) *	2007-04-13	2009-12-16	西安力邦制药有限公司	一种静脉注射用高稳定长循环脂肪乳载药制剂

2009
- 2009-07-22 CA CA2731353A patent/CA2731353A1/en not_active Abandoned
- 2009-07-22 EP EP09768245A patent/EP2317978A2/en not_active Withdrawn
- 2009-07-22 AU AU2009280803A patent/AU2009280803B2/en not_active Ceased
- 2009-07-22 EA EA201100069A patent/EA201100069A1/ru unknown
- 2009-07-22 NZ NZ590730A patent/NZ590730A/xx not_active IP Right Cessation
- 2009-07-22 MX MX2011000795A patent/MX2011000795A/es unknown
- 2009-07-22 CN CN2009801287862A patent/CN102105134B/zh not_active Expired - Fee Related
- 2009-07-22 JP JP2011519283A patent/JP5635504B2/ja not_active Expired - Fee Related
- 2009-07-22 US US13/055,613 patent/US20110275705A1/en not_active Abandoned
- 2009-07-22 KR KR1020117001821A patent/KR20110036075A/ko not_active Ceased
- 2009-07-22 BR BRPI0916535A patent/BRPI0916535A2/pt not_active Application Discontinuation
- 2009-07-22 WO PCT/IN2009/000416 patent/WO2010018596A2/en not_active Ceased
2011
- 2011-01-18 ZA ZA2011/00465A patent/ZA201100465B/en unknown

Also Published As

Publication number	Publication date
CA2731353A1 (en)	2010-02-18
CN102105134A (zh)	2011-06-22
NZ590730A (en)	2012-10-26
CN102105134B (zh)	2013-08-14
WO2010018596A2 (en)	2010-02-18
ZA201100465B (en)	2012-02-29
EA201100069A1 (ru)	2011-10-31
WO2010018596A3 (en)	2010-06-24
JP5635504B2 (ja)	2014-12-03
AU2009280803A1 (en)	2010-02-18
KR20110036075A (ko)	2011-04-06
EP2317978A2 (en)	2011-05-11
MX2011000795A (es)	2011-03-29
AU2009280803B2 (en)	2013-10-31
JP2011529042A (ja)	2011-12-01
US20110275705A1 (en)	2011-11-10

Legal Events

Date	Code	Title	Description
2016-04-12	B11A	Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
2016-07-26	B11Y	Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]

Publication	Publication Date	Title
BRPI0916535A2 (pt)	2015-11-10	nanoemulsão de docetaxel de óleo em água estável injectável.
BRPI0920565A2 (pt)	2015-12-29	emulsão de óleo em água
BRPI1011423A2 (pt)	2016-03-15	composição injetável, kit e método cosmético.
BRPI0922158A2 (pt)	2015-12-29	nanoemulsões
BRPI0919155A2 (pt)	2015-12-08	composição aquosa injetável
HRP20181528T1 (hr)	2018-11-16	Stabilne emulzije ulja u vodi
BRPI1010774A2 (pt)	2016-03-22	método de uso de particulados.
BRPI0912271A2 (pt)	2015-10-20	co-autoria estruturada
EP2499580A4 (en)	2015-04-29	SOCIAL BROWSING
EP2497456A4 (en)	2015-07-29	OIL-IN-WATER emulsified cosmetic
BRPI0918823A2 (pt)	2019-09-24	beta-glicosidases modificadas com estabilidades aperfeicoada
NL1036050C (nl)	2010-04-13	Brandvertragende en brandwerende samenstelling.
BRPI1016117A2 (pt)	2016-04-12	derivados de isoxazol-isoxazol e isoxasol-isotiazol.
EP2412362A4 (en)	2015-05-27	COMPOSITION OF A WATER EMULSION IN OIL
BRPI0909488A2 (pt)	2015-12-22	brocha
BRPI0918668A2 (pt)	2015-08-25	Alimentos emulsificados
EP2274525A4 (en)	2013-07-17	CAMP
BRPI1006024A2 (pt)	2016-05-10	composição cosmética emulsificada
BRPI0908859A2 (pt)	2017-06-06	composição farmacêutica estabilizada de líquído único contedo docetaxel
BRPI0917182A2 (pt)	2015-11-24	turbina de combustão com combustão descontínua
BRPI1013361A2 (pt)	2016-03-29	método para evitar e tratar hipermeabilidade.
IT1392670B1 (it)	2012-03-16	Iniettore
DE112009000730A5 (de)	2011-02-17	Gleitlager
BRPI0922070A2 (pt)	2015-12-15	turbina.
BRPI0915880A2 (pt)	2015-11-03	turbina hidráulica