BRPI0917722A2 - organismo transgênico e método para manipular o teor de malonatos em um organismo transgênico - Google Patents
organismo transgênico e método para manipular o teor de malonatos em um organismo transgênicoInfo
- Publication number
- BRPI0917722A2 BRPI0917722A2 BRPI0917722A BRPI0917722A BRPI0917722A2 BR PI0917722 A2 BRPI0917722 A2 BR PI0917722A2 BR PI0917722 A BRPI0917722 A BR PI0917722A BR PI0917722 A BRPI0917722 A BR PI0917722A BR PI0917722 A2 BRPI0917722 A2 BR PI0917722A2
- Authority
- BR
- Brazil
- Prior art keywords
- transgenic organism
- manipulating
- malonate content
- malonate
- content
- Prior art date
Links
- 230000009261 transgenic effect Effects 0.000 title 2
- OFOBLEOULBTSOW-UHFFFAOYSA-L Malonate Chemical compound [O-]C(=O)CC([O-])=O OFOBLEOULBTSOW-UHFFFAOYSA-L 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13892208P | 2008-12-18 | 2008-12-18 | |
| PCT/US2009/068000 WO2010080388A1 (en) | 2008-12-18 | 2009-12-15 | Reducing byproduction of malonates in a fermentation process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0917722A2 true BRPI0917722A2 (pt) | 2017-05-30 |
Family
ID=41820237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0917722A BRPI0917722A2 (pt) | 2008-12-18 | 2009-12-15 | organismo transgênico e método para manipular o teor de malonatos em um organismo transgênico |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9175318B2 (pt) |
| EP (1) | EP2358862B1 (pt) |
| JP (1) | JP5620402B2 (pt) |
| CN (1) | CN102257126B (pt) |
| AU (1) | AU2009335903B2 (pt) |
| BR (1) | BRPI0917722A2 (pt) |
| CA (1) | CA2744716C (pt) |
| CL (1) | CL2011001462A1 (pt) |
| WO (1) | WO2010080388A1 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2594890B2 (ja) | 1994-12-22 | 1997-03-26 | コーアツ工業株式会社 | 道路用路肩ブロックの構造 |
| US8399226B2 (en) | 2009-06-16 | 2013-03-19 | E I Du Pont De Nemours And Company | High eicosapentaenoic acid oils from improved optimized strains of Yarrowia lipolytica |
| DK2442666T3 (da) | 2009-06-16 | 2015-07-13 | Du Pont | Olier med højt indhold af eicosapentaensyre fra forbedrede og optimerede stammer af yarrowia lipolytica |
| CA2761589C (en) | 2009-06-16 | 2017-12-19 | E. I. Du Pont De Nemours And Company | Improved optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production |
| EP2561050A1 (en) | 2010-04-22 | 2013-02-27 | E.I. Du Pont De Nemours And Company | Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass |
| CN103249834B (zh) | 2010-08-26 | 2016-10-26 | 纳幕尔杜邦公司 | 生产高水平二十碳五烯酸的重组微生物宿主细胞 |
| EP2609202A1 (en) | 2010-08-26 | 2013-07-03 | E.I. Du Pont De Nemours And Company | Mutant hpgg motif and hdash motif delta-5 desaturases and their use in making polyunsaturated fatty acids |
| US8980589B2 (en) | 2010-08-26 | 2015-03-17 | E I Du Pont De Nemours And Company | Mutant delta-9 elongases and their use in making polyunsaturated fatty acids |
| JP2014503216A (ja) | 2010-12-30 | 2014-02-13 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | スクロース利用のための、ヤロウィア・リポリティカ（Ｙａｒｒｏｗｉａｌｉｐｏｌｙｔｉｃａ）におけるサッカロミセス・セレビシア（Ｓａｃｃｈａｒｏｍｙｃｅｓｃｅｒｅｖｉｓｉａｅ）ＳＵＣ２遺伝子の使用 |
| US20130040340A1 (en) | 2011-02-07 | 2013-02-14 | E. I. Du Pont De Nemours And Company | Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms |
| CN103841825B (zh) | 2011-02-11 | 2017-03-22 | 纳幕尔杜邦公司 | 从微生物生物质中获取含脂质组合物的方法 |
| US9005940B2 (en) | 2012-12-21 | 2015-04-14 | E I Du Pont De Nemours And Company | Down-regulation of a polynucleotide encoding a Sou2 sorbitol utilization protein to modify lipid production in microbial cells |
| DE102015202013B4 (de) | 2015-02-05 | 2019-05-09 | Adidas Ag | Verfahren zur Herstellung eines Kunststoffformteils, Kunststoffformteil und Schuh |
| WO2016130597A1 (en) * | 2015-02-10 | 2016-08-18 | GeneSys Consulting, LLC | Methylmalonic acid compositions, biological methods for making same, and microorganisms for making same |
| DE102016209045B4 (de) | 2016-05-24 | 2022-05-25 | Adidas Ag | Verfahren und vorrichtung zum automatischen herstellen von schuhsohlen, sohlen und schuhe |
| DE102016209044B4 (de) | 2016-05-24 | 2019-08-29 | Adidas Ag | Sohlenform zum Herstellen einer Sohle und Anordnung einer Vielzahl von Sohlenformen |
| DE102016209046B4 (de) | 2016-05-24 | 2019-08-08 | Adidas Ag | Verfahren zur herstellung einer schuhsohle, schuhsohle, schuh und vorgefertigte tpu-gegenstände |
| DE102016223980B4 (de) | 2016-12-01 | 2022-09-22 | Adidas Ag | Verfahren zur Herstellung eines Kunststoffformteils |
| DE102017205830B4 (de) | 2017-04-05 | 2020-09-24 | Adidas Ag | Verfahren für die Nachbehandlung einer Vielzahl einzelner expandierter Partikel für die Herstellung mindestens eines Teils eines gegossenen Sportartikels, Sportartikel und Sportschuh |
| CN110063161B (zh) * | 2019-03-20 | 2021-09-10 | 广州中医药大学(广州中医药研究院) | 一种利用田菁茎瘤固氮根瘤菌促进穿心莲生长并提高其有效成分含量的方法 |
| EP4323528A4 (en) * | 2021-04-13 | 2025-07-09 | Debut Biotechnology Inc | BIOPRODUCTION OF FLAVONOIDS AND ANTHOCYANINS USING MICROORGANISM HOSTS |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5071764A (en) | 1983-10-06 | 1991-12-10 | Pfizer Inc. | Process for integrative transformation of yarrowia lipolytica |
| US4880741A (en) | 1983-10-06 | 1989-11-14 | Pfizer Inc. | Process for transformation of Yarrowia lipolytica |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5107065A (en) | 1986-03-28 | 1992-04-21 | Calgene, Inc. | Anti-sense regulation of gene expression in plant cells |
| JP2527340B2 (ja) | 1986-12-15 | 1996-08-21 | アプライド バイオシステムズ インコーポレイテッド | ロ―ダミン染料の５−及び６−スクシニミジルカルボキシレ―ト異性体 |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| JP2002503447A (ja) | 1997-12-04 | 2002-02-05 | スミスクライン・ビーチャム・コーポレイション | 発現可能なアンチセンス配列を用いる条件発現変異細胞の取得方法 |
| US6939691B1 (en) | 1999-10-13 | 2005-09-06 | Board Of Trustees Of The Leland Stanford Junior University | E. coli and Streptomyces host cells that contain MatBC genes or E. coli host cells that contain pcc genes useful for enhanced polyketide production |
| US6998256B2 (en) * | 2000-04-28 | 2006-02-14 | Kosan Biosciences, Inc. | Methods of obtaining epothilone D using crystallization and /or by the culture of cells in the presence of methyl oleate |
| TWI324181B (en) | 2001-04-16 | 2010-05-01 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7214491B2 (en) | 2003-05-07 | 2007-05-08 | E. I. Du Pont De Nemours And Company | Δ-12 desaturase gene suitable for altering levels of polyunsaturated fatty acids in oleaginous yeasts |
| US7238482B2 (en) | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| US7125672B2 (en) | 2003-05-07 | 2006-10-24 | E. I. Du Pont De Nemours And Company | Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts |
| US7259255B2 (en) | 2003-06-25 | 2007-08-21 | E. I. Du Pont De Nemours And Company | Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast |
| US7504259B2 (en) | 2003-11-12 | 2009-03-17 | E. I. Du Pont De Nemours And Company | Δ12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast |
| EP1682566B1 (en) | 2003-11-12 | 2013-06-05 | E.I. Du Pont De Nemours And Company | Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast |
| WO2006012325A1 (en) | 2004-06-25 | 2006-02-02 | E.I. Dupont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| US7465564B2 (en) | 2004-08-10 | 2008-12-16 | E.I. Du Pont De Nemours And Company | Production of γ-linolenic acid in oleaginous yeast |
| KR101340580B1 (ko) * | 2004-10-12 | 2013-12-11 | 보드 오브 트러스티즈 오브 미시건 스테이트 유니버시티 | 플로로글루시놀의 생합성 및 이로부터1,3-디하이드록시벤젠의 합성 |
| US7617795B2 (en) | 2004-10-13 | 2009-11-17 | Embrex, Inc. | Methods and apparatus for injecting and sampling material through avian egg membranes |
| US7588931B2 (en) | 2004-11-04 | 2009-09-15 | E. I. Du Pont De Nemours And Company | High arachidonic acid producing strains of Yarrowia lipolytica |
| DE102004062294A1 (de) * | 2004-12-23 | 2006-07-06 | Basf Plant Science Gmbh | Verfahren zur Herstellung von mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen |
| US7772444B2 (en) * | 2005-05-19 | 2010-08-10 | E. I. Du Pont De Nemours And Company | Method for the production of resveratrol in a recombinant oleaginous microorganism |
| WO2006124999A2 (en) | 2005-05-19 | 2006-11-23 | E. I. Du Pont De Nemours And Company | Method for the production of resveratrol in a recombinant bacterial host cell |
| US7470532B2 (en) | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
| KR20080071190A (ko) | 2005-11-23 | 2008-08-01 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 델타-９ 일롱가제, 및 다중불포화 지방산 생성에 있어서의이들의 용도 |
| US7695950B2 (en) | 2006-05-17 | 2010-04-13 | E. I. Du Pont De Nemours And Company | Δ5 desaturase and its use in making polyunsaturated fatty acids |
| US7678560B2 (en) | 2006-05-17 | 2010-03-16 | E.I. Du Pont De Nemours And Company | Δ 5 desaturase and its use in making polyunsaturated fatty acids |
| EP2087105B1 (en) | 2006-10-30 | 2015-02-25 | E.I. Du Pont De Nemours And Company | Delta 17 desaturase and its use in making polyunsaturated fatty acids |
| US7709239B2 (en) | 2006-12-07 | 2010-05-04 | E.I. Du Pont De Nemours And Company | Mutant Δ8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids |
| MX2009010574A (es) | 2007-04-03 | 2009-10-22 | Du Pont | Multienzimas y su uso en la fabricacion de acidos grasos poliinsaturados. |
| US7794701B2 (en) * | 2007-04-16 | 2010-09-14 | E.I. Du Pont De Nemours And Company | Δ-9 elongases and their use in making polyunsaturated fatty acids |
| CA2701130A1 (en) * | 2007-10-03 | 2009-04-09 | E.I. Du Pont De Nemours And Company | Peroxisome biogenesis factor protein (pex) disruptions for altering the content of polyunsaturated fatty acids and the total lipid content in oleaginous eukaryotic organisms |
| JP5711968B2 (ja) | 2007-10-03 | 2015-05-07 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ | 高エイコサペンタエン酸を生成するためのヤロウィア・リポリティカ（ＹａｒｒｏｗｉａＬｉｐｏｌｙｔｉｃａ）の最適化株 |
-
2009
- 2009-12-15 WO PCT/US2009/068000 patent/WO2010080388A1/en not_active Ceased
- 2009-12-15 US US12/637,877 patent/US9175318B2/en active Active
- 2009-12-15 EP EP09771642.7A patent/EP2358862B1/en not_active Not-in-force
- 2009-12-15 JP JP2011542327A patent/JP5620402B2/ja not_active Expired - Fee Related
- 2009-12-15 CA CA2744716A patent/CA2744716C/en not_active Expired - Fee Related
- 2009-12-15 CN CN200980151146.3A patent/CN102257126B/zh not_active Expired - Fee Related
- 2009-12-15 BR BRPI0917722A patent/BRPI0917722A2/pt not_active Application Discontinuation
- 2009-12-15 AU AU2009335903A patent/AU2009335903B2/en not_active Ceased
-
2011
- 2011-06-16 CL CL2011001462A patent/CL2011001462A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2744716A1 (en) | 2010-07-15 |
| US20100159558A1 (en) | 2010-06-24 |
| WO2010080388A1 (en) | 2010-07-15 |
| JP2012512656A (ja) | 2012-06-07 |
| AU2009335903A1 (en) | 2010-07-15 |
| CA2744716C (en) | 2017-05-23 |
| CN102257126A (zh) | 2011-11-23 |
| EP2358862B1 (en) | 2017-08-02 |
| JP5620402B2 (ja) | 2014-11-05 |
| CL2011001462A1 (es) | 2012-03-30 |
| CN102257126B (zh) | 2014-07-09 |
| US9175318B2 (en) | 2015-11-03 |
| EP2358862A1 (en) | 2011-08-24 |
| AU2009335903B2 (en) | 2016-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |