BRPI0917993A2 - composições de célula-tronco mesenquimal purificada e métodos de purificação de composições de célula-tronco mesenquimal purificda. - Google Patents
composições de célula-tronco mesenquimal purificada e métodos de purificação de composições de célula-tronco mesenquimal purificda.Info
- Publication number
- BRPI0917993A2 BRPI0917993A2 BRPI0917993A BRPI0917993A BRPI0917993A2 BR PI0917993 A2 BRPI0917993 A2 BR PI0917993A2 BR PI0917993 A BRPI0917993 A BR PI0917993A BR PI0917993 A BRPI0917993 A BR PI0917993A BR PI0917993 A2 BRPI0917993 A2 BR PI0917993A2
- Authority
- BR
- Brazil
- Prior art keywords
- stem cell
- mesenchymal stem
- cell compositions
- purified mesenchymal
- purification
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8889808P | 2008-08-14 | 2008-08-14 | |
| US61/088,898 | 2008-08-14 | ||
| PCT/US2009/053891 WO2010019886A1 (en) | 2008-08-14 | 2009-08-14 | Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0917993A2 true BRPI0917993A2 (pt) | 2017-10-10 |
| BRPI0917993B1 BRPI0917993B1 (pt) | 2020-12-29 |
| BRPI0917993B8 BRPI0917993B8 (pt) | 2021-05-25 |
Family
ID=41669330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0917993A BRPI0917993B8 (pt) | 2008-08-14 | 2009-08-14 | composições de célula-tronco mesenquimal purificada |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US8637004B2 (pt) |
| EP (3) | EP3124601B1 (pt) |
| JP (7) | JP6025329B2 (pt) |
| AR (2) | AR073069A1 (pt) |
| AU (1) | AU2009281809B2 (pt) |
| BR (1) | BRPI0917993B8 (pt) |
| CA (1) | CA2733985C (pt) |
| DK (1) | DK2318519T3 (pt) |
| ES (2) | ES2608974T3 (pt) |
| IL (1) | IL211214A0 (pt) |
| MX (2) | MX2011001730A (pt) |
| NZ (2) | NZ602248A (pt) |
| WO (1) | WO2010019886A1 (pt) |
| ZA (1) | ZA201101858B (pt) |
Families Citing this family (37)
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| CA2564679C (en) | 2004-03-22 | 2015-06-23 | Osiris Therapeutics, Inc. | Mesenchymal stem cells and uses therefor |
| CN101370930A (zh) | 2006-01-13 | 2009-02-18 | 奥西里斯治疗公司 | 表达TNF-α受体的间充质干细胞 |
| MX2011001730A (es) | 2008-08-14 | 2011-03-24 | Osiris Therapeutics Inc | Composiciones purificadas de celulas madre mesenquimales y metodos para purificar composiciones de celulas madre mesenquimales. |
| NZ591292A (en) | 2008-08-20 | 2012-10-26 | Anthrogenesis Corp | Improved cell composition and methods of making the same |
| US9192695B2 (en) | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
| WO2012048093A2 (en) | 2010-10-08 | 2012-04-12 | Osiris Therapeutics, Inc. | Enhanced msc preparations |
| US9725689B2 (en) | 2010-10-08 | 2017-08-08 | Terumo Bct, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| ITGE20120034A1 (it) * | 2012-03-28 | 2013-09-29 | Carlo Tremolada | Preparato e metodo per la produzione di un preparato comprendente cellule staminali mesenchimali |
| JP2013252126A (ja) * | 2012-05-08 | 2013-12-19 | Otsuka Pharmaceut Factory Inc | デキストラン含有肺塞栓形成予防用哺乳動物細胞懸濁液 |
| WO2014150784A1 (en) | 2013-03-15 | 2014-09-25 | Allosource | Cell repopulated collagen matrix for soft tissue repair and regeneration |
| EP3068867B1 (en) | 2013-11-16 | 2018-04-18 | Terumo BCT, Inc. | Expanding cells in a bioreactor |
| US11008547B2 (en) | 2014-03-25 | 2021-05-18 | Terumo Bct, Inc. | Passive replacement of media |
| EP3198006B1 (en) | 2014-09-26 | 2021-03-24 | Terumo BCT, Inc. | Scheduled feed |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| AU2017241626B2 (en) | 2016-03-28 | 2022-03-31 | Gallant Pet, Inc. | Viable cell compositions, and methods related to same |
| US10251990B2 (en) | 2016-04-29 | 2019-04-09 | Fenwal, Inc. | System and method for processing, incubating, and/or selecting biological cells |
| EP3238760B1 (en) * | 2016-04-29 | 2019-10-02 | Fenwal, Inc. | System and method for selecting and culturing cells |
| WO2017205667A1 (en) | 2016-05-25 | 2017-11-30 | Terumo Bct, Inc. | Cell expansion |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| EP3338823B1 (en) | 2016-12-21 | 2021-06-16 | Fenwal, Inc. | System and method for separating cells incorporating magnetic separation |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| JP7393945B2 (ja) | 2017-03-31 | 2023-12-07 | テルモ ビーシーティー、インコーポレーテッド | 細胞増殖 |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| WO2019102268A1 (en) | 2017-11-22 | 2019-05-31 | Mesoblast International Sarl | Cellular compositions and methods of treatment i |
| WO2019204646A1 (en) | 2018-04-18 | 2019-10-24 | Xencor, Inc. | Lag-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and lag-3 antigen binding domains |
| WO2020084135A1 (en) * | 2018-10-26 | 2020-04-30 | Stemselect | Method and apparatus for mesenchymal stem cells isolation and purification |
| US11618776B2 (en) | 2018-12-20 | 2023-04-04 | Xencor, Inc. | Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15RA and NKG2D antigen binding domains |
| US12702683B2 (en) | 2019-01-03 | 2026-08-11 | Mesoblast International Sárl | Method for improving visual acuity |
| WO2020231968A1 (en) * | 2019-05-15 | 2020-11-19 | Stemcyte Inc. | High concentration cell packaging and shipping |
| WO2021144995A1 (ja) * | 2020-01-16 | 2021-07-22 | PuREC株式会社 | 高純度間葉系幹細胞 |
| WO2021176001A1 (en) | 2020-03-05 | 2021-09-10 | Mesoblast International Sàrl | Method for treating inflammatory lung diseases using mesenchymal lineage precursor or stem cells |
| WO2021226373A2 (en) | 2020-05-08 | 2021-11-11 | Gallant Pet, Inc. | Uterine-derived regenerative cell compositions and uses thereof |
| EP4314244B1 (en) | 2021-03-23 | 2025-07-23 | Terumo BCT, Inc. | Cell capture and expansion |
| US12152699B2 (en) | 2022-02-28 | 2024-11-26 | Terumo Bct, Inc. | Multiple-tube pinch valve assembly |
| USD1099116S1 (en) | 2022-09-01 | 2025-10-21 | Terumo Bct, Inc. | Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device |
| CN115478046A (zh) * | 2022-09-30 | 2022-12-16 | 浙江泉生生物科技有限公司 | 一种降低血清培养体系中细胞制剂bsa残留量的方法 |
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-
2009
- 2009-08-14 MX MX2011001730A patent/MX2011001730A/es active IP Right Grant
- 2009-08-14 DK DK09807366.1T patent/DK2318519T3/en active
- 2009-08-14 ES ES09807366.1T patent/ES2608974T3/es active Active
- 2009-08-14 JP JP2011523195A patent/JP6025329B2/ja active Active
- 2009-08-14 ES ES16189444T patent/ES3071914T3/es active Active
- 2009-08-14 NZ NZ602248A patent/NZ602248A/en unknown
- 2009-08-14 BR BRPI0917993A patent/BRPI0917993B8/pt active IP Right Grant
- 2009-08-14 WO PCT/US2009/053891 patent/WO2010019886A1/en not_active Ceased
- 2009-08-14 MX MX2014008542A patent/MX362512B/es unknown
- 2009-08-14 US US12/541,282 patent/US8637004B2/en active Active
- 2009-08-14 AU AU2009281809A patent/AU2009281809B2/en active Active
- 2009-08-14 NZ NZ591146A patent/NZ591146A/xx unknown
- 2009-08-14 EP EP16189444.9A patent/EP3124601B1/en active Active
- 2009-08-14 EP EP24209880.4A patent/EP4477742A3/en active Pending
- 2009-08-14 EP EP09807366.1A patent/EP2318519B1/en not_active Revoked
- 2009-08-14 CA CA2733985A patent/CA2733985C/en active Active
- 2009-08-18 AR ARP090103159A patent/AR073069A1/es not_active Application Discontinuation
-
2011
- 2011-02-14 IL IL211214A patent/IL211214A0/en active IP Right Grant
- 2011-03-10 ZA ZA2011/01858A patent/ZA201101858B/en unknown
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2013
- 2013-12-16 US US14/107,031 patent/US20140105872A1/en not_active Abandoned
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2014
- 2014-11-04 JP JP2014224180A patent/JP2015071610A/ja active Pending
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2017
- 2017-01-04 JP JP2017000107A patent/JP2017081972A/ja active Pending
- 2017-05-23 US US15/602,848 patent/US20180008642A1/en not_active Abandoned
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2018
- 2018-03-01 JP JP2018036415A patent/JP2018109052A/ja active Pending
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2019
- 2019-11-25 US US16/694,382 patent/US20200197444A1/en not_active Abandoned
-
2020
- 2020-04-15 JP JP2020072934A patent/JP7580202B2/ja active Active
- 2020-05-05 AR ARP200101271A patent/AR123811A2/es not_active Application Discontinuation
-
2022
- 2022-09-23 US US17/934,852 patent/US20230089901A1/en not_active Abandoned
-
2023
- 2023-01-05 JP JP2023000381A patent/JP2023052211A/ja active Pending
-
2025
- 2025-03-20 US US19/086,003 patent/US20250312379A1/en active Pending
- 2025-05-23 JP JP2025086455A patent/JP2025122125A/ja active Pending
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