BRPI0918178A2 - anticorpos monoclonais para tratamento de câncer - Google Patents
anticorpos monoclonais para tratamento de câncerInfo
- Publication number
- BRPI0918178A2 BRPI0918178A2 BRPI0918178A BRPI0918178A BRPI0918178A2 BR PI0918178 A2 BRPI0918178 A2 BR PI0918178A2 BR PI0918178 A BRPI0918178 A BR PI0918178A BR PI0918178 A BRPI0918178 A BR PI0918178A BR PI0918178 A2 BRPI0918178 A2 BR PI0918178A2
- Authority
- BR
- Brazil
- Prior art keywords
- monoclonal antibodies
- cancer treatment
- cancer
- treatment
- monoclonal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9745308P | 2008-09-16 | 2008-09-16 | |
| EP08016277A EP2166021A1 (en) | 2008-09-16 | 2008-09-16 | Monoclonal antibodies for treatment of cancer |
| US61/097,453 | 2008-09-16 | ||
| EP08016277.9 | 2008-09-16 | ||
| PCT/EP2009/006704 WO2010031551A2 (en) | 2008-09-16 | 2009-09-16 | Monoclonal antibodies for treatment of cancer |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| BRPI0918178A2 true BRPI0918178A2 (pt) | 2015-12-01 |
| BRPI0918178A8 BRPI0918178A8 (pt) | 2020-05-19 |
| BRPI0918178B1 BRPI0918178B1 (pt) | 2021-04-06 |
| BRPI0918178B8 BRPI0918178B8 (pt) | 2021-05-25 |
Family
ID=40589589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0918178A BRPI0918178B8 (pt) | 2008-09-16 | 2009-09-16 | anticorpos monoclonais para tratamento de câncer |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US8946388B2 (pt) |
| EP (3) | EP2166021A1 (pt) |
| JP (1) | JP2012502938A (pt) |
| KR (1) | KR101818741B1 (pt) |
| CN (3) | CN105753988A (pt) |
| AU (1) | AU2009294896B2 (pt) |
| BR (1) | BRPI0918178B8 (pt) |
| CA (1) | CA2732594C (pt) |
| CY (1) | CY1119956T1 (pt) |
| DK (1) | DK2342234T3 (pt) |
| ES (1) | ES2659718T3 (pt) |
| HK (1) | HK1253579A1 (pt) |
| HR (1) | HRP20180262T1 (pt) |
| HU (1) | HUE036477T2 (pt) |
| IL (2) | IL211010A (pt) |
| LT (1) | LT2342234T (pt) |
| MX (2) | MX357010B (pt) |
| NO (1) | NO2342234T3 (pt) |
| NZ (2) | NZ596490A (pt) |
| PL (1) | PL2342234T3 (pt) |
| PT (1) | PT2342234T (pt) |
| RS (1) | RS56937B1 (pt) |
| SI (1) | SI2342234T1 (pt) |
| SM (1) | SMT201800079T1 (pt) |
| TR (1) | TR201802090T4 (pt) |
| WO (1) | WO2010031551A2 (pt) |
| ZA (1) | ZA201100835B (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1762575A1 (en) | 2005-09-12 | 2007-03-14 | Ganymed Pharmaceuticals AG | Identification of tumor-associated antigens for diagnosis and therapy |
| EP1970384A1 (en) | 2007-03-14 | 2008-09-17 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| US9193763B2 (en) | 2007-08-17 | 2015-11-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
| EP2166021A1 (en) | 2008-09-16 | 2010-03-24 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
| EP2371864A1 (en) | 2010-03-23 | 2011-10-05 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| WO2012098407A1 (en) * | 2011-01-19 | 2012-07-26 | Cantargia Ab | Anti - il1rap antibodies and their use for treating human |
| US20130236890A1 (en) * | 2012-03-08 | 2013-09-12 | HI-STEM Heidelberg Institute for Stem Cell Technology and Experimental Medicine gGmbH | Novel method for analyzing circulating tumor cells of a patient for the presence of metastasis-initiating cells |
| KR101471253B1 (ko) * | 2012-10-29 | 2014-12-10 | 인제대학교 산학협력단 | 암 표적 항체 및 이를 포함하는 암 예방 또는 치료용 조성물 |
| AU2013344778C1 (en) | 2012-11-15 | 2024-06-27 | Endocyte, Inc. | Conjugates for treating diseases caused by PSMA expressing cells |
| WO2015172800A1 (en) * | 2014-05-12 | 2015-11-19 | Numab Ag | Novel multispecific molecules and novel treatment methods based on such multispecific molecules |
| EP3456700A1 (en) | 2013-10-18 | 2019-03-20 | Deutsches Krebsforschungszentrum | Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer |
| CN105849568B (zh) | 2013-11-14 | 2018-05-04 | 恩多塞特公司 | 用于正电子发射断层术的化合物 |
| US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
| CN116327915A (zh) * | 2015-04-03 | 2023-06-27 | 佐马技术有限公司 | 使用TGF-β抑制剂和PD-1抑制剂治疗癌症 |
| AU2016291803A1 (en) * | 2015-07-14 | 2018-02-22 | Medlmmune, Llc | Compositions and methods for treating cancer |
| JP6951825B2 (ja) * | 2015-09-04 | 2021-10-20 | ザ スクリプス リサーチ インスティテュート | インスリン免疫グロブリン融合タンパク質 |
| BR112018011100A2 (pt) * | 2015-12-01 | 2018-12-04 | Genmab B.V. | anticorpo, composição, construto de ácido nucleico, vetor de expressão, célula hospedeira, método para tratamento de um indivíduo que tem um câncer, kit de partes, e, uso de um anticorpo ou de uma composição. |
| EP3411071A4 (en) * | 2016-10-20 | 2019-08-28 | I-Mab | NOVEL MONOCLONAL CD47 ANTIBODY AND USES THEREOF |
| US20200087390A1 (en) | 2016-12-21 | 2020-03-19 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| CN106632661A (zh) * | 2017-01-10 | 2017-05-10 | 天津东亚生物技术有限公司 | 利用hla‑g分子及其抗原片段制备预防肿瘤和病毒病的广谱疫苗及其应用 |
| EP3597735A4 (en) * | 2017-03-15 | 2020-11-25 | Suzhou Galaxy Biopharma, Co., Ltd. | CTLA4 ANTIBODIES, PHARMACEUTICAL COMPOSITION AND USES THEREOF |
| CN107556369A (zh) * | 2017-08-23 | 2018-01-09 | 天津国际生物医药联合研究院 | 一种抗原肽和用于检测肿瘤细胞的抗体制备方法及其应用 |
| KR20210003135A (ko) | 2018-04-17 | 2021-01-11 | 엔도사이트, 인코포레이티드 | 암의 치료 방법 |
| CN109402064B (zh) * | 2018-11-05 | 2021-05-14 | 湖南省肿瘤医院 | 杂交瘤细胞株及其产生的单克隆抗体和应用 |
| JP7604397B2 (ja) | 2019-05-20 | 2024-12-23 | エンドサイト・インコーポレイテッド | Psmaコンジュゲートの調製方法 |
| KR102266418B1 (ko) * | 2019-07-30 | 2021-06-16 | 한국생명공학연구원 | 영여자 추출물을 유효성분으로 함유하는 전립선 질환의 예방 및 치료용 조성물 |
Family Cites Families (52)
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|---|---|---|---|---|
| US4475196A (en) | 1981-03-06 | 1984-10-02 | Zor Clair G | Instrument for locating faults in aircraft passenger reading light and attendant call control system |
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4474893A (en) | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US4486194A (en) | 1983-06-08 | 1984-12-04 | James Ferrara | Therapeutic device for administering medicaments through the skin |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| US5374548A (en) | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| MX9203291A (es) | 1985-06-26 | 1992-08-01 | Liposome Co Inc | Metodo para acoplamiento de liposomas. |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4954617A (en) | 1986-07-07 | 1990-09-04 | Trustees Of Dartmouth College | Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes |
| US4881175A (en) | 1986-09-02 | 1989-11-14 | Genex Corporation | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| EP0307434B2 (en) | 1987-03-18 | 1998-07-29 | Scotgen Biopharmaceuticals, Inc. | Altered antibodies |
| US5013653A (en) | 1987-03-20 | 1991-05-07 | Creative Biomolecules, Inc. | Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5258498A (en) | 1987-05-21 | 1993-11-02 | Creative Biomolecules, Inc. | Polypeptide linkers for production of biosynthetic proteins |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
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| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| GB8809129D0 (en) | 1988-04-18 | 1988-05-18 | Celltech Ltd | Recombinant dna methods vectors and host cells |
| US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
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| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| US20020065394A1 (en) * | 1998-03-18 | 2002-05-30 | Kenneth Jacobs | Secreted proteins and polynucleotides encoding them |
| US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| EP1311530A4 (en) | 2000-08-03 | 2004-10-06 | Wim-Van Schooten | PRODUCTION OF HUMANIZED ANTIBODIES IN TRANSGENIC ANIMALS |
| US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| IL155977A0 (en) | 2000-11-30 | 2003-12-23 | Medarex Inc | Transgenic transchromosomal rodents for making human antibodies |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| AU2003209459A1 (en) | 2002-03-06 | 2003-09-16 | Hybrigenics | Protein-protein interactions in human tumours involving bcmp-7 and bcmp-11 |
| KR20110017020A (ko) | 2002-10-17 | 2011-02-18 | 젠맵 에이/에스 | Cd20에 대한 인간 모노클로날 항체 |
| WO2004065629A1 (en) | 2003-01-17 | 2004-08-05 | The Chinese University Of Hong Kong | Circulating mrna as diagnostic markers for pregnancy-related disorders |
| US20050255114A1 (en) * | 2003-04-07 | 2005-11-17 | Nuvelo, Inc. | Methods and diagnosis for the treatment of preeclampsia |
| CN1663603A (zh) | 2004-03-02 | 2005-09-07 | 北京大学 | 一种肿瘤-胎盘抗原蛋白及其dna在肿瘤治疗中的应用 |
| EP1762575A1 (en) | 2005-09-12 | 2007-03-14 | Ganymed Pharmaceuticals AG | Identification of tumor-associated antigens for diagnosis and therapy |
| EP1970384A1 (en) * | 2007-03-14 | 2008-09-17 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| EP2166021A1 (en) | 2008-09-16 | 2010-03-24 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| ES2963717T3 (es) * | 2009-02-20 | 2024-04-01 | Astellas Pharma Inc | Métodos y composiciones para el diagnóstico y tratamiento del cáncer |
| EP2221063A1 (en) * | 2009-02-20 | 2010-08-25 | Ganymed Pharmaceuticals AG | Methods and compositions for diagnosis and treatment of cancer |
-
2008
- 2008-09-16 EP EP08016277A patent/EP2166021A1/en not_active Withdrawn
-
2009
- 2009-09-16 AU AU2009294896A patent/AU2009294896B2/en not_active Ceased
- 2009-09-16 HU HUE09778564A patent/HUE036477T2/hu unknown
- 2009-09-16 WO PCT/EP2009/006704 patent/WO2010031551A2/en not_active Ceased
- 2009-09-16 US US13/119,027 patent/US8946388B2/en not_active Expired - Fee Related
- 2009-09-16 BR BRPI0918178A patent/BRPI0918178B8/pt not_active IP Right Cessation
- 2009-09-16 EP EP17201134.8A patent/EP3312198A1/en not_active Withdrawn
- 2009-09-16 NZ NZ596490A patent/NZ596490A/xx not_active IP Right Cessation
- 2009-09-16 DK DK09778564.6T patent/DK2342234T3/en active
- 2009-09-16 LT LTEP09778564.6T patent/LT2342234T/lt unknown
- 2009-09-16 CN CN201510373379.5A patent/CN105753988A/zh active Pending
- 2009-09-16 NZ NZ591004A patent/NZ591004A/en not_active IP Right Cessation
- 2009-09-16 MX MX2015005367A patent/MX357010B/es unknown
- 2009-09-16 KR KR1020117007149A patent/KR101818741B1/ko not_active Expired - Fee Related
- 2009-09-16 PL PL09778564T patent/PL2342234T3/pl unknown
- 2009-09-16 JP JP2011527243A patent/JP2012502938A/ja active Pending
- 2009-09-16 CA CA2732594A patent/CA2732594C/en not_active Expired - Fee Related
- 2009-09-16 RS RS20180160A patent/RS56937B1/sr unknown
- 2009-09-16 SI SI200931801T patent/SI2342234T1/en unknown
- 2009-09-16 CN CN200980136101.9A patent/CN102164963B/zh not_active Expired - Fee Related
- 2009-09-16 HR HRP20180262TT patent/HRP20180262T1/hr unknown
- 2009-09-16 ES ES09778564.6T patent/ES2659718T3/es active Active
- 2009-09-16 PT PT97785646T patent/PT2342234T/pt unknown
- 2009-09-16 EP EP09778564.6A patent/EP2342234B1/en active Active
- 2009-09-16 SM SM20180079T patent/SMT201800079T1/it unknown
- 2009-09-16 CN CN201410649373.1A patent/CN104628858B/zh not_active Expired - Fee Related
- 2009-09-16 MX MX2011002856A patent/MX2011002856A/es active IP Right Grant
- 2009-09-16 TR TR2018/02090T patent/TR201802090T4/tr unknown
- 2009-09-16 NO NO09778564A patent/NO2342234T3/no unknown
-
2011
- 2011-02-01 ZA ZA2011/00835A patent/ZA201100835B/en unknown
- 2011-02-02 IL IL211010A patent/IL211010A/en not_active IP Right Cessation
-
2015
- 2015-10-22 IL IL242204A patent/IL242204B/en active IP Right Grant
-
2018
- 2018-02-15 CY CY20181100189T patent/CY1119956T1/el unknown
- 2018-10-08 HK HK18112784.5A patent/HK1253579A1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
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