BRPI0918795A2 - dispositivo e método de sequenciação de polinucleotídeo alvo - Google Patents

dispositivo e método de sequenciação de polinucleotídeo alvo

Info

Publication number
BRPI0918795A2
BRPI0918795A2 BRPI0918795A BRPI0918795A BRPI0918795A2 BR PI0918795 A2 BRPI0918795 A2 BR PI0918795A2 BR PI0918795 A BRPI0918795 A BR PI0918795A BR PI0918795 A BRPI0918795 A BR PI0918795A BR PI0918795 A2 BRPI0918795 A2 BR PI0918795A2
Authority
BR
Brazil
Prior art keywords
target polynucleotide
sequencing device
polynucleotide sequencing
target
sequencing
Prior art date
Application number
BRPI0918795A
Other languages
English (en)
Inventor
Jonathan O Halloran
Original Assignee
Quantumdx Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quantumdx Group Ltd filed Critical Quantumdx Group Ltd
Publication of BRPI0918795A2 publication Critical patent/BRPI0918795A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721Investigating individual macromolecules, e.g. by translocation through nanopores

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
BRPI0918795A 2008-09-03 2009-09-03 dispositivo e método de sequenciação de polinucleotídeo alvo BRPI0918795A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9402508P 2008-09-03 2008-09-03
US9400608P 2008-09-03 2008-09-03
PCT/IB2009/006976 WO2010026488A2 (en) 2008-09-03 2009-09-03 Methods and kits for nucleic acid sequencing

Publications (1)

Publication Number Publication Date
BRPI0918795A2 true BRPI0918795A2 (pt) 2015-12-01

Family

ID=41582235

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0918795A BRPI0918795A2 (pt) 2008-09-03 2009-09-03 dispositivo e método de sequenciação de polinucleotídeo alvo

Country Status (8)

Country Link
US (2) US9410196B2 (pt)
EP (1) EP2321429B1 (pt)
JP (2) JP5818683B2 (pt)
CN (1) CN102203288A (pt)
BR (1) BRPI0918795A2 (pt)
ES (1) ES2594873T3 (pt)
WO (1) WO2010026488A2 (pt)
ZA (1) ZA201102252B (pt)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2321429B1 (en) 2008-09-03 2016-08-17 Quantumdx Group Limited Methods and kits for nucleic acid sequencing
US10759824B2 (en) 2008-09-03 2020-09-01 Quantumdx Group Limited Design, synthesis and use of synthetic nucleotides comprising charge mass tags
WO2013154750A1 (en) 2012-04-10 2013-10-17 The Trustees Of Columbia Unversity In The City Of New York Systems and methods for biological ion channel interfaces
DE112010002222B4 (de) 2009-06-04 2024-01-25 Leidos Innovations Technology, Inc. (n.d.Ges.d. Staates Delaware) Mehr-Proben-Mikrofluidchip fur DNA-Analyse
US9399217B2 (en) 2010-10-04 2016-07-26 Genapsys, Inc. Chamber free nanoreactor system
NZ610129A (en) 2010-10-04 2014-08-29 Genapsys Inc Systems and methods for automated reusable parallel biological reactions
US9184099B2 (en) 2010-10-04 2015-11-10 The Board Of Trustees Of The Leland Stanford Junior University Biosensor devices, systems and methods therefor
GB2497501A (en) 2010-10-15 2013-06-12 Lockheed Corp Micro fluidic optic design
CN103620403B (zh) * 2011-01-11 2016-08-10 纽约市哥伦比亚大学理事会 使用纳米管监测单分子的系统和方法
EP2678669A1 (en) 2011-02-23 2014-01-01 The Trustees of Columbia University in the City of New York Systems and methods for single-molecule detection using nanopores
US9926596B2 (en) 2011-05-27 2018-03-27 Genapsys, Inc. Systems and methods for genetic and biological analysis
US8585973B2 (en) 2011-05-27 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Nano-sensor array
KR101940833B1 (ko) * 2011-05-27 2019-01-21 제납시스 인크. 유전자 및 생물학적 분석을 위한 시스템 및 방법
US20130225416A1 (en) * 2011-11-29 2013-08-29 Gabriela Altmann Electronic sequencing
CN106591103B (zh) 2011-12-01 2021-06-04 吉纳普赛斯股份有限公司 用于高效电子测序与检测的系统和方法
WO2013100949A1 (en) * 2011-12-28 2013-07-04 Intel Corporation Nanogap transducers with selective surface immobilization sites
CN107828877A (zh) 2012-01-20 2018-03-23 吉尼亚科技公司 基于纳米孔的分子检测与测序
US9341592B2 (en) * 2012-04-09 2016-05-17 Bharath Takulapalli Field effect transistor, device including the transistor, and methods of forming and using same
JP2015528282A (ja) * 2012-08-06 2015-09-28 クワンタムディーエックス・グループ・リミテッド 核酸シークエンシングのための方法およびキット
EP2909343B1 (en) * 2012-10-16 2018-10-10 Abbott Molecular Inc. Methods to sequence a nucleic acid
EP2971141B1 (en) 2013-03-15 2018-11-28 Genapsys, Inc. Systems for biological analysis
WO2015089238A1 (en) 2013-12-11 2015-06-18 Genapsys, Inc. Systems and methods for biological analysis and computation
US10190161B2 (en) 2014-04-03 2019-01-29 Stmicroelectronics S.R.L. Apparatus and method for nucleic acid sequencing based on nanowire detectors
US9765326B2 (en) * 2014-04-03 2017-09-19 Stmicroelectronics S.R.L. Apparatus and method for nucleic acid sequencing based on nanochannels
WO2015161119A1 (en) * 2014-04-16 2015-10-22 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Digital protein sensing chip and methods for detection of low concentrations of molecules
EP3556864B1 (en) 2014-04-18 2020-12-09 Genapsys, Inc. Methods and systems for nucleic acid amplification
US9506908B2 (en) 2014-10-06 2016-11-29 Alveo Technologies, Inc. System for detection of analytes
US10352899B2 (en) 2014-10-06 2019-07-16 ALVEO Technologies Inc. System and method for detection of silver
US10196678B2 (en) 2014-10-06 2019-02-05 ALVEO Technologies Inc. System and method for detection of nucleic acids
US9921182B2 (en) 2014-10-06 2018-03-20 ALVEO Technologies Inc. System and method for detection of mercury
US10627358B2 (en) 2014-10-06 2020-04-21 Alveo Technologies, Inc. Method for detection of analytes
CN104498353B (zh) * 2014-11-05 2016-08-31 苏州国科芯感医疗科技有限公司 恒温扩增压电核酸检测系统
EP3277845B1 (en) * 2015-03-30 2021-07-07 Genapsys Inc. Beads for nucleic acid sequencing
CN105021680A (zh) * 2015-06-30 2015-11-04 上海集成电路研发中心有限公司 基于石墨烯传感器检测MicroRNA的方法
EP3400444A4 (en) 2016-01-04 2019-10-16 QuantuMDx Group Limited DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES WITH LOADING MASS MARKINGS
CN106191230A (zh) * 2016-02-02 2016-12-07 杭州格磊思沃科技有限公司 用氨基酸结合脱氧核苷酸进行dna测序的方法
WO2017184790A1 (en) 2016-04-19 2017-10-26 Takulapalli Bharath Nanopore sensor, structure and device including the sensor, and methods of forming and using same
US10544456B2 (en) 2016-07-20 2020-01-28 Genapsys, Inc. Systems and methods for nucleic acid sequencing
CN109996888A (zh) 2016-09-23 2019-07-09 阿尔韦奥科技公司 用于检测分析物的方法和组合物
CA3076378A1 (en) 2017-09-21 2019-03-28 Genapsys, Inc. Systems and methods for nucleic acid sequencing
EP3899022A4 (en) 2018-12-20 2023-03-01 Alveo Technologies Inc. PORTABLE IMPEDANCE-BASED DIAGNOSTIC TEST SYSTEM FOR DETECTING ANALYTES
DE102019200929A1 (de) * 2019-01-25 2020-07-30 Robert Bosch Gmbh Verfahren und Vorrichtung zum optischen Erfassen einer Länge eines Makromoleküls
US12472492B2 (en) 2020-08-14 2025-11-18 Alveo Technologies, Inc. Systems and methods of sample depositing and testing
CN113636931B (zh) * 2021-08-05 2024-02-13 康龙化成(宁波)科技发展有限公司 基因编码化合物库起始头片段化合物及其在基因编码化合物库合成上的应用

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6346413B1 (en) * 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US6261797B1 (en) 1996-01-29 2001-07-17 Stratagene Primer-mediated polynucleotide synthesis and manipulation techniques
US6780982B2 (en) * 1996-07-12 2004-08-24 Third Wave Technologies, Inc. Charge tags and the separation of nucleic acid molecules
US6942771B1 (en) * 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
KR20030049802A (ko) 2001-12-17 2003-06-25 권윤정 바이오 칩에서 프로브와 시료 핵산의 혼성화 여부를 효소반응으로 구별하는 방법
US6815167B2 (en) 2002-04-25 2004-11-09 Geneohm Sciences Amplification of DNA to produce single-stranded product of defined sequence and length
US20030215816A1 (en) * 2002-05-20 2003-11-20 Narayan Sundararajan Method for sequencing nucleic acids by observing the uptake of nucleotides modified with bulky groups
AU2003298672A1 (en) 2002-11-19 2005-01-28 Singulex, Inc. Detection of target molecules through interaction with probes
US7371524B2 (en) 2003-06-17 2008-05-13 Hannjorg Hereth Substituted azaporphyrins as fluorescence labels
JP4342890B2 (ja) 2003-09-30 2009-10-14 富士フイルム株式会社 ミスマッチ結合ポリヌクレオチドの除去方法
EP1689764B1 (en) 2003-11-19 2013-01-02 AlleLogic Biosciences Corporation Oligonucleotides labeled with a plurality of fluorophores
US20070117104A1 (en) * 2005-11-22 2007-05-24 Buzby Philip R Nucleotide analogs
US9035035B2 (en) 2004-11-05 2015-05-19 Genovoxx Gmbh Macromolecular nucleotide compounds and methods for using the same
RU2400538C2 (ru) 2005-03-05 2010-09-27 Сиджен, Инк. Олигонуклеотид с двойственной специфичностью и способы, в которых он используется
EP1902143A1 (en) * 2005-03-29 2008-03-26 Applera Corporation Nanowire-based system for analysis of nucleic acids
JP2007195548A (ja) * 2005-12-28 2007-08-09 Canon Inc 塩基配列に関する情報取得方法、及び情報取得装置
WO2007077952A1 (en) * 2005-12-28 2007-07-12 Canon Kabushiki Kaisha Method and device for determining a nucleic acid allele or base sequence
EP3978121A1 (en) 2006-07-19 2022-04-06 BioNano Genomics, Inc. Nanonozzle device arrays: their preparation and use for macromolecular analysis
KR101504640B1 (ko) 2006-12-05 2015-03-20 레이저젠, 인코퍼레이티드 광절단가능 표지된 뉴클레오티드와 뉴클레오시드, 표지된 뉴클레오티드와 뉴클레오시드, 그리고 dna 염기서열분석에서 이들의 이용 방법
EP2156179B1 (en) * 2007-04-04 2021-08-18 The Regents of The University of California Methods for using a nanopore
JP2010532485A (ja) * 2007-06-29 2010-10-07 アプライド バイオシステムズ ナノfetを含む電子検出のためのシステムおよび方法
US20110281740A1 (en) 2008-06-30 2011-11-17 Joseph Beechem Methods for Real Time Single Molecule Sequencing
EP3002288B1 (en) 2008-09-03 2019-12-04 Quantumdx Group Limited Design, synthesis and use of synthetic nucleotides comprising ionic reporter groups
EP2321429B1 (en) 2008-09-03 2016-08-17 Quantumdx Group Limited Methods and kits for nucleic acid sequencing
CN102186989B (zh) 2008-09-03 2021-06-29 纳伯塞斯2.0有限责任公司 用于流体通道中生物分子和其它分析物的电压感测的纵向移位纳米级电极的使用
US8715933B2 (en) 2010-09-27 2014-05-06 Nabsys, Inc. Assay methods using nicking endonucleases
CN102242062B (zh) 2011-04-19 2012-12-19 浙江大学 一种高分辨率的生物传感器
CN202284206U (zh) 2011-08-02 2012-06-27 浙江大学 一种高分辨率的生物传感器
JP2015528282A (ja) 2012-08-06 2015-09-28 クワンタムディーエックス・グループ・リミテッド 核酸シークエンシングのための方法およびキット

Also Published As

Publication number Publication date
US9410196B2 (en) 2016-08-09
CN102203288A (zh) 2011-09-28
WO2010026488A3 (en) 2010-04-22
JP5818683B2 (ja) 2015-11-18
JP6284506B2 (ja) 2018-02-28
EP2321429A2 (en) 2011-05-18
ES2594873T3 (es) 2016-12-23
US20110165572A1 (en) 2011-07-07
US9938573B2 (en) 2018-04-10
JP2012501643A (ja) 2012-01-26
JP2016025851A (ja) 2016-02-12
WO2010026488A2 (en) 2010-03-11
EP2321429B1 (en) 2016-08-17
US20170037463A1 (en) 2017-02-09
ZA201102252B (en) 2011-11-30

Similar Documents

Publication Publication Date Title
BRPI0918795A2 (pt) dispositivo e método de sequenciação de polinucleotídeo alvo
BRPI0917288A2 (pt) sensor de biomems e aparelhos e métodos para o mesmo
BRPI0912934A2 (pt) aparelho e método
FI20085334A7 (fi) Harjoitusmenetelmä ja -järjestelmä
BRPI0910713A2 (pt) método e aparelhos
BR112012001771A2 (pt) controlador do sensor de nível e método
EP2427572A4 (en) SEQUENCING METHOD
BRPI1009686A2 (pt) método de exercio e aparelho de exercícios
BRPI0822414A2 (pt) Conjunto de dispositivo intramedular e método associado
BR112012004162A2 (pt) aparelho de análise de água
BRPI0912788A2 (pt) navegação de aparelho e método
BRPI0910897A2 (pt) sistema e método de tratamento de água
EP2433143A4 (en) MULTIDIRECTIONAL MICROFLUIDIC DEVICES AND METHODS
BRPI0822675A2 (pt) Sistema de display e método
BRPI1008917A2 (pt) dispositivo de exibição e método de exibição
BR112012011910A2 (pt) dispositivo e método
EP2349500A4 (en) DEVICE AND EXERCISE SYSTEM
DE112010000822T8 (de) Automatische Analysevorrichtung und automatisches Analyseverfahren
BRPI0717659A2 (pt) Método de alocação de sequência e aparelho de alocação de sequência
BRPI0909748A2 (pt) sistema e método de simulação
BRPI0909635A2 (pt) aparelho desumidificador e método
BR112012015031A2 (pt) aparelho e método
BRPI0917905A2 (pt) dispositivo de memória e método do mesmo
BRPI0918982A2 (pt) aparelho e sistema de tratamento de água
BRPI1006494A2 (pt) dispositivo e metodo de localização de descargas parciais

Legal Events

Date Code Title Description
B07A Technical examination (opinion): publication of technical examination (opinion)
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application according art. 36 industrial patent law
B09A Decision: intention to grant
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time