BRPI0919174A2 - composições imunocontraceptivas recombinantes à base do vírus da raiva e métodos de uso - Google Patents

composições imunocontraceptivas recombinantes à base do vírus da raiva e métodos de uso

Info

Publication number: BRPI0919174A2
Authority: BR; Brazil
Prior art keywords: methods; rabies virus; recombinant rabies; compositions; based immunocontraceptive
Prior art date: 2008-09-17

Application number

BRPI0919174A

Other languages

English (en)

Inventor

Charles Rupprecht

Xianfu Wu

Original Assignee

Government Of The Us Secretary Of The Dept Of Health And Human Services Ct S For Disease Control And

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-09-17

Filing date

2009-08-20

Publication date

2015-12-15

2009-08-20 Application filed by Government Of The Us Secretary Of The Dept Of Health And Human Services Ct S For Disease Control And filed Critical Government Of The Us Secretary Of The Dept Of Health And Human Services Ct S For Disease Control And

2015-12-15 Publication of BRPI0919174A2 publication Critical patent/BRPI0919174A2/pt

2020-11-17 Publication of BRPI0919174B1 publication Critical patent/BRPI0919174B1/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20141—Use of virus, viral particle or viral elements as a vector
- C12N2760/20143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Genetics & Genomics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Mycology (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Zoology (AREA)
Biochemistry (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Reproductive Health (AREA)
Tropical Medicine & Parasitology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0919174-7A 2008-09-17 2009-08-20 vírus da raiva recombinante, composição imunogênica e seu uso BRPI0919174B1 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US9774808P	2008-09-17	2008-09-17
US61/097,748		2008-09-17
PCT/US2009/054502 WO2010033337A1 (en)	2008-09-17	2009-08-20	Rabies virus-based recombinant immunocontraceptive compositions and methods of use

Publications (2)

Publication Number	Publication Date
BRPI0919174A2 true BRPI0919174A2 (pt)	2015-12-15
BRPI0919174B1 BRPI0919174B1 (pt)	2020-11-17

Family

ID=41217642

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0919174-7A BRPI0919174B1 (pt)	2008-09-17	2009-08-20	vírus da raiva recombinante, composição imunogênica e seu uso

Country Status (7)

Country	Link
US (1)	US8524247B2 (pt)
EP (1)	EP2344193B1 (pt)
CN (1)	CN102159240B (pt)
BR (1)	BRPI0919174B1 (pt)
CA (1)	CA2736604C (pt)
WO (1)	WO2010033337A1 (pt)
ZA (1)	ZA201102006B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2011163446A2 (en) *	2010-06-24	2011-12-29	The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention	Pan-lyssavirus vaccines against rabies
CA2886161A1 (en)	2012-09-29	2014-04-03	The Trustees Of The University Of Pennsylvania	Veterinary composition and methods for non-surgical neutering and castration
US20140271716A1 (en) *	2013-03-15	2014-09-18	Ark Sciences, Inc.	Intra-testicular Injection of Immunogens
WO2014189654A1 (en) *	2013-05-23	2014-11-27	Thomas Jefferson University	Co-immunization with attenuated rabies virus and non-rabies antigen
WO2022200762A1 (en) *	2021-03-26	2022-09-29	Sporomex Limited	Methods for the extraction of dispersible microcapsules (immunocontraception)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4608251A (en)	1984-11-09	1986-08-26	Pitman-Moore, Inc.	LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues
WO1988005308A1 (en)	1987-01-14	1988-07-28	Commonwealth Scientific And Industrial Research Or	Anti reproductive hormone
US5484592A (en)	1989-03-23	1996-01-16	Stitching Centraal Diergeneeskundig Instituut	Peptide, immunogenic composition and vaccine or medicinal preparation: a method of immunising a mammal against LHRH, and a method of improving the meat quality of pigs
WO1991002799A1 (en)	1989-08-25	1991-03-07	Biotechnology Australia Pty Ltd	Fusion proteins
WO1993025231A1 (en)	1992-06-05	1993-12-23	Dalhousie University	Use of zona pellucida glycoproteins for immunocontraception
ATE275191T1 (de)	1992-11-09	2004-09-15	Zonagen Inc	Methoden für die immunoempfängnisverhütung
US5759551A (en)	1993-04-27	1998-06-02	United Biomedical, Inc.	Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
USRE39048E1 (en)	1995-06-07	2006-03-28	Pepscan Systems B.V.	Peptide, immunogenic composition and vaccine or medical preparation, a method to immunise animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine
DE60017211T2 (de) *	1999-02-17	2005-06-02	Pfizer Products Inc., Groton	Fusionsproteine mit Trägern welche eine doppelte Immunantwort induzieren
US7074413B2 (en)	2000-03-23	2006-07-11	Thomas Jefferson University	Genetically engineered rabies recombinant vaccine for immunization of stray dogs and wildlife
CN100346826C (zh) *	2001-07-20	2007-11-07	乔治亚大学研究基金会	通过核蛋白在磷酸化位点突变的减弱狂犬病病毒用于抗狂犬病的接种以及在cns中的基因治疗
WO2003030933A1 (en) *	2001-10-10	2003-04-17	Thomas Jefferson University	Recombinant rabies vaccine and methods of preparation and use
US7056515B2 (en)	2002-02-08	2006-06-06	Immunovaccine Technologies Inc.	Antigens for immunocontraception
AU2003262379A1 (en) *	2002-04-16	2003-11-03	Auburn University	TRANSIENT AND/OR PERMANENT MODIFICATION OF SEXUAL BEHAVIOR AND/OR FERTILITY USING RECOMBINANT CHIMERIC GnRH
AU2003270779A1 (en)	2002-09-20	2004-04-08	The United States Of America As Represented By The Secretary Of Agriculture	Vaccine compositions and adjuvant
WO2006017276A2 (en) *	2004-07-12	2006-02-16	Thomas Jefferson University	Recombinant rabies virus compositions
BRPI0617373B1 (pt) *	2005-10-14	2022-04-05	The Goverment of The United States of America, Representado por, The Secretary of The Department of Health and Human Services, Centers for Disease Control and Prevention	Composições e métodos do vírus da raiva

2009
- 2009-08-20 BR BRPI0919174-7A patent/BRPI0919174B1/pt not_active IP Right Cessation
- 2009-08-20 CA CA2736604A patent/CA2736604C/en active Active
- 2009-08-20 WO PCT/US2009/054502 patent/WO2010033337A1/en not_active Ceased
- 2009-08-20 US US13/062,680 patent/US8524247B2/en not_active Expired - Fee Related
- 2009-08-20 EP EP09791746.2A patent/EP2344193B1/en not_active Not-in-force
- 2009-08-20 CN CN200980136612.0A patent/CN102159240B/zh not_active Expired - Fee Related
2011
- 2011-03-16 ZA ZA2011/02006A patent/ZA201102006B/en unknown

Also Published As

Publication number	Publication date
WO2010033337A8 (en)	2011-04-14
EP2344193B1 (en)	2013-10-02
US8524247B2 (en)	2013-09-03
CN102159240A (zh)	2011-08-17
CN102159240B (zh)	2014-12-24
CA2736604A1 (en)	2010-03-25
WO2010033337A1 (en)	2010-03-25
CA2736604C (en)	2017-01-03
ZA201102006B (en)	2014-06-25
BRPI0919174B1 (pt)	2020-11-17
EP2344193A1 (en)	2011-07-20
US20110165189A1 (en)	2011-07-07

Legal Events

Date	Code	Title	Description
2018-03-20	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]	Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-08-13	B07G	Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]	Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.
2019-11-05	B06U	Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
2020-04-07	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2020-09-08	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2020-11-17	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 17/11/2020, OBSERVADAS AS CONDICOES LEGAIS.
2025-06-17	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: EXTINTA A PATENTE, NOS TERMOS DO ARTIGO 86, DA LPI, E ARTIGO 14 DA PORTARIA 52/2023, REFERENTE AO NAO RECOLHIMENTO DA 16A RETRIBUICAO ANUAL (VIDE PARECER).
2025-10-14	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2841 DE 17-06-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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