BRPI0919696A2 - Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado. - Google Patents

Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado.

Info

Publication number
BRPI0919696A2
BRPI0919696A2 BRPI0919696-0A BRPI0919696A BRPI0919696A2 BR PI0919696 A2 BRPI0919696 A2 BR PI0919696A2 BR PI0919696 A BRPI0919696 A BR PI0919696A BR PI0919696 A2 BRPI0919696 A2 BR PI0919696A2
Authority
BR
Brazil
Prior art keywords
isolated polynucleotide
substantially purified
recombinant microorganism
purified polypeptide
polypeptide
Prior art date
Application number
BRPI0919696-0A
Other languages
English (en)
Inventor
James C Liao
Kechun Zhang
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of BRPI0919696A2 publication Critical patent/BRPI0919696A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/03—Acyl groups converted into alkyl on transfer (2.3.3)
    • C12Y203/03013—2-Isopropylmalate synthase (2.3.3.13)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0919696-0A 2008-10-18 2009-10-18 Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado. BRPI0919696A2 (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US10656308P 2008-10-18 2008-10-18
US10656108P 2008-10-18 2008-10-18
US10656208P 2008-10-18 2008-10-18
US10656408P 2008-10-18 2008-10-18
US11930808P 2008-12-02 2008-12-02
PCT/US2009/061116 WO2010045629A2 (en) 2008-10-18 2009-10-18 Production of c5-c8 alcohols using evolved enzymes and metabolically engineered microorganisms

Publications (1)

Publication Number Publication Date
BRPI0919696A2 true BRPI0919696A2 (pt) 2015-08-04

Family

ID=42107306

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919696-0A BRPI0919696A2 (pt) 2008-10-18 2009-10-18 Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado.

Country Status (4)

Country Link
US (1) US8298798B2 (pt)
EP (1) EP2346991B1 (pt)
BR (1) BRPI0919696A2 (pt)
WO (1) WO2010045629A2 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010221863A1 (en) * 2009-03-11 2011-10-06 Dsm Ip Assets B.V. Preparation of adipic acid
BR112012003241A2 (pt) 2009-08-12 2015-09-01 Gevo Inc Localização de via de isobutanol citosólico para a produção de isobutanol
US9206443B2 (en) 2011-03-14 2015-12-08 Easel Biotechnologies, Llc Microbial synthesis of aldehydes and corresponding alcohols
WO2013025277A1 (en) * 2011-08-15 2013-02-21 Exxonmobil Chemical Patents Inc. Esters and their preparation and use
CA2854450C (en) 2011-11-03 2020-04-21 Easel Biotechnologies, Llc Microbial production of n-butyraldehyde
WO2014037912A2 (en) * 2012-09-07 2014-03-13 Cellworks Research India Pvt. Ltd Methods for production of isobutanol through nutrient stress and genetically modified microorganisms thereof
WO2015089127A1 (en) * 2013-12-12 2015-06-18 Dow Global Technologies Llc Processes to prepare elongated 2-ketoacids and c6-c10 compounds therefrom via genetic modifications to microbial metabolic pathways
US10260060B2 (en) 2014-12-10 2019-04-16 Dow Global Technologies Llc Genetically modified phenylpyruvate decarboxylase, processes to prepare, and uses thereof
WO2017040378A1 (en) * 2015-08-28 2017-03-09 The Regents Of The University Of California Discovery of enzymes from the alpha-keto acid decarboxylase family
EP3519579B1 (en) 2016-09-30 2025-11-05 Dow Global Technologies LLC Processes to prepare elongated 2-ketoacids and c-5-c10 compounds therefrom via genetic modifications to microbial metabolic pathways
US11230705B2 (en) 2017-09-29 2022-01-25 Dow Global Technologies Llc Genetically modified isopropylmalate isomerase enzyme complexes and processes to prepare elongated 2-ketoacids and C5-C10 compounds therewith
US10808265B2 (en) 2018-09-26 2020-10-20 Nantbio, Inc. Microbes and methods for improved conversion of a feedstock
JP7764852B2 (ja) 2019-09-25 2025-11-06 味の素株式会社 細菌の発酵による２－メチル酪酸の製造方法
WO2021178805A1 (en) 2020-03-06 2021-09-10 Gevo, Inc. Novel nkr variants for increased production of isobutanol
JP2023518045A (ja) * 2020-03-18 2023-04-27 ランザテク，インコーポレイテッド ガス基質からの２－フェニルエタノールの発酵産生

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2201454C2 (ru) * 1999-07-09 2003-03-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Мутантная альфа-изопропилмалат синтаза (ipms), днк, кодирующая мутантную ipms, способ получения штамма escherichia coli, способ получения l-лейцина
US20030167513A1 (en) * 2001-11-30 2003-09-04 Mourad George S. Selection and use of isopropylmalate synthase (IPMS) mutants desensitized in L-leucine negative feedback control
JP2005296010A (ja) * 2004-03-19 2005-10-27 Osaka Univ ２−イソプロピルリンゴ酸シンターゼ活性を有する新規耐熱性タンパク質
PL389665A1 (pl) * 2007-02-09 2010-07-05 The Regents of the University of CaliforniaThe Regents of the University of California Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy

Also Published As

Publication number Publication date
EP2346991A2 (en) 2011-07-27
US20110201083A1 (en) 2011-08-18
US8298798B2 (en) 2012-10-30
WO2010045629A2 (en) 2010-04-22
WO2010045629A3 (en) 2010-08-19
EP2346991A4 (en) 2013-03-27
EP2346991B1 (en) 2016-12-28

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.