BRPI0919861A2 - metodos para a separacao, caracterizacao e/ou identificacao de micro-organismos por espectroscopia raman - Google Patents

metodos para a separacao, caracterizacao e/ou identificacao de micro-organismos por espectroscopia raman

Info

Publication number
BRPI0919861A2
BRPI0919861A2 BRPI0919861A BRPI0919861A BRPI0919861A2 BR PI0919861 A2 BRPI0919861 A2 BR PI0919861A2 BR PI0919861 A BRPI0919861 A BR PI0919861A BR PI0919861 A BRPI0919861 A BR PI0919861A BR PI0919861 A2 BRPI0919861 A2 BR PI0919861A2
Authority
BR
Brazil
Prior art keywords
characterization
microorganisms
identification
separation
methods
Prior art date
Application number
BRPI0919861A
Other languages
English (en)
Inventor
Clay Bradford
Ronsick Christopher
Walsh John
Hyman Jones
Thorpe Thurman
Original Assignee
Bio Merieux Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Merieux Inc filed Critical Bio Merieux Inc
Publication of BRPI0919861A2 publication Critical patent/BRPI0919861A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3581—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using far infrared light; using Terahertz radiation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
BRPI0919861A 2008-10-31 2009-10-30 metodos para a separacao, caracterizacao e/ou identificacao de micro-organismos por espectroscopia raman BRPI0919861A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11018708P 2008-10-31 2008-10-31
PCT/US2009/005886 WO2010062351A1 (en) 2008-10-31 2009-10-30 Methods for separation, characterization, and/or identification of microorganisms using raman spectroscopy

Publications (1)

Publication Number Publication Date
BRPI0919861A2 true BRPI0919861A2 (pt) 2017-04-04

Family

ID=42542822

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919861A BRPI0919861A2 (pt) 2008-10-31 2009-10-30 metodos para a separacao, caracterizacao e/ou identificacao de micro-organismos por espectroscopia raman

Country Status (11)

Country Link
US (1) US20100136609A1 (pt)
EP (1) EP2361377B1 (pt)
JP (1) JP2012507283A (pt)
KR (1) KR20110095277A (pt)
CN (1) CN102272585B (pt)
AU (1) AU2009320332B2 (pt)
BR (1) BRPI0919861A2 (pt)
CA (1) CA2741036C (pt)
MX (1) MX2011004106A (pt)
RU (1) RU2541775C2 (pt)
WO (1) WO2010062351A1 (pt)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009020680A2 (en) * 2007-05-04 2009-02-12 Stanford University Molecular imaging of living subjects using raman spectroscopy and labeled raman nanoparticles
US8512975B2 (en) * 2008-07-24 2013-08-20 Biomerieux, Inc. Method for detection and characterization of a microorganism in a sample using time dependent spectroscopic measurements
KR20110091719A (ko) * 2008-10-31 2011-08-12 바이오메리욱스, 인코포레이티드. 식별제를 사용한 미생물의 분리 및 특성규명 방법
FR2942806B1 (fr) * 2009-03-03 2011-09-02 Assist Publ Hopitaux De Paris Procede d'identification de germes en milieu liquide
EP2333105A1 (en) * 2009-12-08 2011-06-15 Koninklijke Philips Electronics N.V. Selective lysis of cells
EP2439536A1 (en) 2010-10-01 2012-04-11 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO New classification method for spectral data
RU2593005C2 (ru) * 2010-11-05 2016-07-27 Ф. Хоффманн-Ля Рош Аг Спектроскопический фингерпринтинг сырья
US9239318B2 (en) * 2011-02-28 2016-01-19 Waters Technologies Corporation Spectroscopic sample inspection for automated chromatography
CA2831969A1 (en) * 2011-06-06 2012-12-30 Biocartis S.A. Selective lysis of cells by ionic surfactants
DE112012003756B4 (de) * 2011-09-08 2022-03-10 Thermo Electron Scientific Instruments Llc Optisches Emissions- und Transmissionsspektrometer
US9365883B2 (en) 2011-12-19 2016-06-14 Opticul Diagnostics Ltd. Spectroscopic means and methods for identifying microorganisms in culture
US20150186754A1 (en) 2012-07-18 2015-07-02 Nederlandse Organisatie Voor Toegepast- Natuurwetenschappelijk Onderzoek Tno Classification method for spectral data
FR3009387B1 (fr) * 2013-07-31 2016-11-18 Biomerieux Sa Procede et dispositif d'analyse d'un echantillon biologique
CN103499560B (zh) * 2013-09-29 2015-08-05 浙江大学 一种结合拉曼光谱技术和谱峰比值法的藻种鉴别方法
DE102014003386B4 (de) 2014-03-07 2016-06-23 Celltool Gmbh Verfahren und Vorrichtung zur Qualitätskontrolle eines Blutprodukts
JP6113908B2 (ja) * 2014-03-14 2017-04-12 株式会社東芝 分子検出装置および方法
CN106030278A (zh) * 2014-03-25 2016-10-12 马尔文仪器有限公司 分散在液相中的蛋白质的拉曼光谱结构调查研究
CN104165879B (zh) * 2014-08-19 2016-08-17 中国科学院微生物研究所 用于鉴定军团菌毒力的方法
JP6325423B2 (ja) * 2014-10-10 2018-05-16 アズビル株式会社 液中蛍光検出装置及び液中の蛍光の検出方法
CN208367018U (zh) 2015-05-28 2019-01-11 Bd科斯特公司 实验室仪器、对分析物进行试验的自动化系统和移动微生物试验板的机电组件
FR3044415B1 (fr) * 2015-11-27 2017-12-01 Biomerieux Sa Procede de determination de la reaction d'un microorganisme a son exposition a un antibiotique
CN105441546B (zh) * 2015-12-18 2019-03-22 上海交通大学 基于fish的厌氧消化发酵液中产甲烷菌群的检测方法
CN106770150A (zh) * 2016-05-19 2017-05-31 王桂文 一种快速定量单个微孢子虫孢子海藻糖浓度的方法
WO2018033894A1 (en) * 2016-08-19 2018-02-22 Monash University Spectroscopic systems and methods for the identification and quantification of pathogens
CN108342447B (zh) * 2017-01-22 2021-10-15 中国科学院青岛生物能源与过程研究所 一种筛选与已知菌株表型相似的菌株的方法
KR102638609B1 (ko) 2017-07-27 2024-02-19 바이오메리욱스, 인코포레이티드. 격리 튜브
CN107561058B (zh) * 2017-09-12 2020-11-17 青岛啤酒股份有限公司 一种工业Lager酵母菌株风味物质代谢相似性评价方法
MX2020004151A (es) 2017-10-30 2020-08-13 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivacion de virus envueltos en lipidos.
CN107703291A (zh) * 2017-11-23 2018-02-16 中山市创艺生化工程有限公司 用于发光免疫分析法的浓缩缓冲液及其制备方法
FR3075825B1 (fr) 2017-12-21 2022-01-21 Biomerieux Sa Procede et systeme d'identificationdu type de gram d'une bacterie
FR3075824B1 (fr) * 2017-12-21 2022-01-14 Biomerieux Sa Procede d'identification d'une levure ou d'une bacterie
CN108226127B (zh) * 2017-12-26 2021-04-06 深圳国际旅行卫生保健中心 测定疟原虫含量的方法和检测疟原虫含量的系统
CN108827936B (zh) * 2018-06-15 2024-03-08 何坚 一种血液培养报阳检测装置与方法
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
EP3953686A4 (en) * 2019-04-09 2022-12-21 Agency for Science, Technology and Research Label-free detection of mycobacteria using surface enhanced raman spectroscopy
CN110628762A (zh) * 2019-10-14 2019-12-31 杭州同创越诚基因科技有限公司 一种基于纳米磁珠的核酸提取方法及应用
FR3103900B1 (fr) * 2019-11-29 2024-07-19 Univ Du Mans Méthode d'identification rapide de microorganismes par analyse de matrices excitation-émission
CN110849866B (zh) * 2019-11-29 2023-01-17 中国人民解放军军事科学院军事医学研究院 一种利用拉曼散射鉴别新生隐球菌和格特隐球菌的方法
RU2739758C1 (ru) * 2020-03-05 2020-12-28 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр гематологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ гематологии" Минздрава России) Способ идентификации Candida spp. и других дрожжеподобных грибов из положительной гемокультуры методом матричной лазерной десорбционной ионизационной времяпролетной масс-спектрометрии (MALDI-TOF MS) у больных с инфекцией кровотока
KR102382101B1 (ko) * 2021-07-20 2022-04-04 주식회사 지에프퍼멘텍 미생물 발효에 의한 단백질 생산 공정을 제어하는 방법 및 장치
CN113390853B (zh) * 2021-07-21 2023-04-07 中国科学院苏州生物医学工程技术研究所 利用拉曼光谱鉴别细菌和真菌的方法及系统
KR102413155B1 (ko) * 2021-10-14 2022-06-24 주식회사 휴피트 패혈증 진단용 이산화탄소 비색 센서 기반의 미생물 생장배지
CN114216837B (zh) * 2021-11-16 2023-09-29 北京工业大学 联合流式细胞分选和拉曼技术对Tetrasphaera亚群胞内代谢物测定的方法
CN114216894B (zh) * 2022-01-10 2022-10-18 北京工业大学 基于表面增强拉曼光谱技术快速鉴定土壤中木霉菌的方法
US12555691B2 (en) * 2022-02-22 2026-02-17 Hyperspectral Corp. Systems and methods for detecting pathogens using spectrometer scans
KR102485512B1 (ko) * 2022-03-28 2023-01-06 주식회사 지에프퍼멘텍 미생물 발효에 의한 테트라아세틸파이토스핑고신 생산 공정을 제어하는 방법 및 장치
CN115950871B (zh) * 2022-09-23 2023-12-15 北京蓝晶微生物科技有限公司 聚羟基脂肪酸酯含量的检测方法、装置、系统、设备
EP4605731A1 (en) * 2022-10-21 2025-08-27 Janssen Pharmaceutica NV Methods and systems for microbial detection using raman spectroscopy
CN116130004B (zh) * 2023-01-06 2024-05-24 成都侣康科技有限公司 一种抗菌肽的鉴定处理方法和系统

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928139A (en) * 1973-02-12 1975-12-23 Wadley Res Inst & Blood Bank Detection of microbial pathogens
US3932222A (en) * 1974-12-20 1976-01-13 J. K. & Susie L. Wadley Research Institute And Blood Bank For isolating pathogenic microorganisms
US4038150A (en) * 1976-03-24 1977-07-26 J. K. And Susie L. Wadley Research Institute And Blood Bank Sample mixing and centrifugation apparatus
US4131512A (en) * 1976-11-05 1978-12-26 J. K. And Susie L. Wadley Research Institute And Blood Bank Method for detecting microbial pathogens employing a cushioning agent
US4212948A (en) * 1978-10-18 1980-07-15 J. K. And Susie L. Wadley Research Institute And Blood Bank Apparatus for detecting microbial pathogens employing a cushioning agent
US4410630A (en) * 1981-12-11 1983-10-18 The United States Of America As Represented By The Department Of Health And Human Services Lysis filtration culture chamber
US4693972A (en) * 1984-01-16 1987-09-15 Becton, Dickinson And Company Composition and method for rapid detection of microorganisms in clinical samples
US4829005A (en) * 1984-06-15 1989-05-09 Friedman Michael P Sedimentation filtration microorganism growth culture system
US4847198A (en) * 1987-10-07 1989-07-11 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Detection and indentification of bacteria by means of ultra-violet excited resonance Raman spectra
US5474910A (en) * 1993-10-15 1995-12-12 Alfano; Robert R. Method and device for detecting biological molecules and/or microorganisms within a desired area or space
JP3406608B2 (ja) * 1994-03-16 2003-05-12 フォス エレクトリック アクティーゼルスカブ 液体サンプルのコンディショニングのための新しい方法
US5599717A (en) * 1994-09-02 1997-02-04 Martin Marietta Energy Systems, Inc. Advanced synchronous luminescence system
FR2732037B1 (fr) * 1995-03-20 1997-05-30 Dbv Procede de detection de microorganismes par separation et culture sur un systeme gelifie, systeme gelifie et necessaire de dosage pour mettre en oeuvre ce procede, utilisation en microbiologie
EP1062044A2 (en) * 1998-03-10 2000-12-27 Large Scale Proteomics Corporation Detection and characterization of microorganisms
US5948610A (en) * 1998-06-03 1999-09-07 University Of Maryland At Baltimore County Use of matrices comprising liquids and light absorbing particles for analysis of microorganisms by laser desorption mass spectrometry
US20020086289A1 (en) * 1999-06-15 2002-07-04 Don Straus Genomic profiling: a rapid method for testing a complex biological sample for the presence of many types of organisms
WO2001007648A1 (de) * 1999-07-22 2001-02-01 Artus Gesellschaft für molekularbiologische Diagnostik und Entwicklung mbH Verfahren zum speziesspezifischen nachweis von organismen
EP1290428A1 (en) * 2000-06-02 2003-03-12 Medicometrics APS Method and system for classifying a biological sample
FR2829500B1 (fr) * 2001-09-13 2003-12-12 Hemosystem Procede de concentration et de detection de germes pathogenes a partir de produits sanguins et/ou de leurs derives et dispositif pour le mettre en oeuvre
US6780602B2 (en) * 2001-11-01 2004-08-24 Microbiosystems, Limited Partnership Taxonomic identification of pathogenic microorganisms and their toxic proteins
IL162380A0 (en) * 2001-12-03 2005-11-20 Seroptix Inc A method for identifying markers
US7428045B2 (en) * 2002-01-10 2008-09-23 Chemimage Corporation Raman spectral analysis of pathogens
US7186990B2 (en) * 2002-01-22 2007-03-06 Microbiosystems, Limited Partnership Method and apparatus for detecting and imaging the presence of biological materials
JP4745959B2 (ja) * 2003-05-12 2011-08-10 リバー・ダイアグノスティクス・ビー．・ブイ． 微生物の自動特徴づけおよび分類
EP1692512B1 (en) * 2003-12-09 2012-09-05 bioMérieux, Inc. Methods for detecting bacterial pathogens
US7662562B2 (en) * 2004-08-10 2010-02-16 Becton, Dickinson And Company Method for rapid identification of microorganisms
US20070037135A1 (en) * 2005-08-08 2007-02-15 Barnes Russell H System and method for the identification and quantification of a biological sample suspended in a liquid
JP4918281B2 (ja) * 2006-05-18 2012-04-18 シスメックス株式会社 尿中有形成分分析装置
US7542132B2 (en) * 2006-07-31 2009-06-02 Applied Materials, Inc. Raman spectroscopy as integrated chemical metrology
US8280471B2 (en) * 2007-12-12 2012-10-02 Kimberly-Clark Worldwide, Inc. Fiber optic based detection of autofluorescent bacterial pathogens
KR101759995B1 (ko) * 2008-10-31 2017-07-31 바이오메리욱스, 인코포레이티드. 미생물의 분리, 특성규명 및/또는 동정에 사용하기 위한 분리 장치
WO2010062356A1 (en) * 2008-10-31 2010-06-03 Biomerieux, Inc. Methods for separation, characterization and/or identification of microorganisms using spectroscopy

Also Published As

Publication number Publication date
EP2361377B1 (en) 2018-01-31
KR20110095277A (ko) 2011-08-24
RU2541775C2 (ru) 2015-02-20
AU2009320332B2 (en) 2014-07-31
WO2010062351A1 (en) 2010-06-03
CN102272585B (zh) 2015-10-07
EP2361377A1 (en) 2011-08-31
CN102272585A (zh) 2011-12-07
AU2009320332A1 (en) 2010-06-03
MX2011004106A (es) 2011-08-15
CA2741036A1 (en) 2010-06-03
US20100136609A1 (en) 2010-06-03
CA2741036C (en) 2018-01-09
JP2012507283A (ja) 2012-03-29
RU2011114900A (ru) 2012-12-10

Similar Documents

Publication Publication Date Title
BRPI0919861A2 (pt) metodos para a separacao, caracterizacao e/ou identificacao de micro-organismos por espectroscopia raman
BRPI0919895A2 (pt) metodos para a separacao,caracterizacao e/ou identificacao de micro-organismos por espectroscopia,
BRPI0919896A2 (pt) metodos para a separacao,caracterizacao e/ou identificacao de micro-organismos por espectroscopia de massa.
BRPI1010576A2 (pt) métodos para tratamento de distúrbios oncológicos usando transferidores epimetabólicos, moléculas intracelulares multidimensionais ou influenciadores ambientais.
BRPI0920586A2 (pt) dispositivo de separacao para uso na separacao ,caracterizacao e/ou identificacao de micro-organismos.
BRPI0922952A2 (pt) métodos para a caracterização de microorganismos em meios sólidos ou semi-sólidos
AP2010005516A0 (en) Process for the manufacture of hydrocarbons of biological origin.
BRPI0920779A2 (pt) método de produção de óleo biológico.
BRPI0920072A2 (pt) métodos para separação e caracterização de micro-organismos por agentes identificadores
BRPI0915366A2 (pt) dispositivo e processo para produção de farinha e/ou sêmola
DE112010000972A5 (de) Vorrichtung für eine Übertragung von Drehmomenten
BR112012000421A2 (pt) composições e métodos para intensificar a produção de um produto biológico.
BRPI0807744A2 (pt) Aparelho de barbear ou depilar de segurança
BRPI0913292A2 (pt) método de hidroconversão, e, zona de reação de hidroconversão.
BRPI0918349A2 (pt) Processo para preparar dióxido de divinilareno
EP2269026A4 (en) Assay apparatuses, methods and reagents
EP2365879C0 (en) MICROFLUIDIC DEVICE
EP2240759A4 (en) METHOD, DEVICE AND KITS FOR PERIKRITICAL REFLECTION SPECTROSCOPY
BRPI0923401A2 (pt) Métodos para o preparo de aril amidas.
EP2274598B8 (en) Systems and methods for gemstone identification and analysis
EP2242989A4 (en) DEVICE FOR ENHANCED EXPLOSION METHOD
ES2386414T8 (es) Procedimiento para la desparafinación de muestras biológicas
BRPI0813764A2 (pt) Processo para formação de haletos de carbonila alfa, beta-insaturados
EP2307141A4 (en) MICROFLUIDIC DEVICE
BRPI0918633A2 (pt) método para calcinar matérias-primas.

Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: G01N 21/65 , C12M 1/12 , C12M 1/34

Ipc: C12Q 1/04 (1980.01), G01N 21/65 (1980.01), G01N 33

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time