BRPI0920868A2 - captura de partículas - Google Patents
captura de partículasInfo
- Publication number
- BRPI0920868A2 BRPI0920868A2 BRPI0920868A BRPI0920868A BRPI0920868A2 BR PI0920868 A2 BRPI0920868 A2 BR PI0920868A2 BR PI0920868 A BRPI0920868 A BR PI0920868A BR PI0920868 A BRPI0920868 A BR PI0920868A BR PI0920868 A2 BRPI0920868 A2 BR PI0920868A2
- Authority
- BR
- Brazil
- Prior art keywords
- particle capture
- capture
- particle
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0668—Trapping microscopic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70514—CD4
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70517—CD8
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Fluid Mechanics (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10042008P | 2008-09-26 | 2008-09-26 | |
| PCT/US2009/058408 WO2010036912A2 (en) | 2008-09-26 | 2009-09-25 | Capturing particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0920868A2 true BRPI0920868A2 (pt) | 2015-12-22 |
Family
ID=42060400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0920868A BRPI0920868A2 (pt) | 2008-09-26 | 2009-09-25 | captura de partículas |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US9128091B2 (pt) |
| EP (1) | EP2344883A4 (pt) |
| JP (1) | JP2012504243A (pt) |
| CN (1) | CN102227637A (pt) |
| BR (1) | BRPI0920868A2 (pt) |
| WO (1) | WO2010036912A2 (pt) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102227637A (zh) | 2008-09-26 | 2011-10-26 | 通用医疗公司 | 捕获粒子 |
| EP2616551B1 (en) | 2010-09-14 | 2020-08-19 | The Regents of The University of California | Method for isolating cells from heterogeneous solution using microfluidic trapping vortices |
| SG189160A1 (en) | 2010-09-29 | 2013-05-31 | Massachusetts Inst Technology | Device for high throughput investigations of cellular interactions |
| WO2012170560A2 (en) | 2011-06-06 | 2012-12-13 | Cornell University | Microfluidic device for extracting, isolating, and analyzing dna from cells |
| US9417244B2 (en) | 2011-09-28 | 2016-08-16 | The General Hospital Corporation | Cadherins as cancer biomarkers |
| BR112014013756A2 (pt) | 2011-12-07 | 2017-06-13 | Cytovera Inc | método e dispositivo para o processamento de amostra |
| JP5742728B2 (ja) * | 2012-01-06 | 2015-07-01 | コニカミノルタ株式会社 | 細胞分離デバイスおよびこれを用いた細胞分離方法 |
| WO2013181285A1 (en) | 2012-05-29 | 2013-12-05 | The Regents Of The University Of California | Systems, methods and components for isolating cells from a fluid sample |
| CN102719353B (zh) * | 2012-06-13 | 2014-07-30 | 湖南大学 | 一种用于外周血中循环癌细胞的特异性捕获的装置及方法 |
| WO2014116183A1 (en) * | 2013-01-24 | 2014-07-31 | National University Of Singapore | Microdevices for separation of non-spherical particles and applications thereof |
| US9138746B2 (en) | 2013-05-01 | 2015-09-22 | Honeywell International Inc. | Fluid stop for measured sample containment |
| KR101508974B1 (ko) * | 2013-05-14 | 2015-04-07 | 한국과학기술연구원 | 종양 세포의 검출장치 및 검출방법 |
| US11262361B2 (en) | 2013-07-18 | 2022-03-01 | The General Hospital Corporation | Selective capture and release of rare mammalian cells using photodegradable hydrogels in a microfluidic platform |
| FI128658B (en) * | 2013-11-24 | 2020-09-30 | Kemira Oyj | Method and system for analysis of a sample containing solid particles and use of the method and system |
| WO2015115272A1 (ja) | 2014-01-31 | 2015-08-06 | アルプス電気株式会社 | 流路プレート |
| KR101515394B1 (ko) * | 2014-06-09 | 2015-05-04 | 연세대학교 산학협력단 | 세포 용해 미세유체 장치 및 이를 이용한 세포 용해 방법 |
| WO2015200857A1 (en) | 2014-06-27 | 2015-12-30 | The Regents Of The University Of California | Apparatus and method for label-free analysis of rare cells from bodily fluids |
| CN104087506B (zh) * | 2014-07-08 | 2016-02-24 | 西安交通大学 | 一种高通量单细胞反转录pcr分析装置 |
| US10391491B2 (en) | 2014-08-07 | 2019-08-27 | The General Hospital Corporation | Platelet-targeted microfluidic isolation of cells |
| CA2981505A1 (en) * | 2015-04-10 | 2016-10-13 | Tumorgen Mdx Llc | Rare cell isolation device and method of use thereof |
| WO2017181186A1 (en) * | 2016-04-15 | 2017-10-19 | Vortex Biosciences, Inc. | Microfluidic chips and cartridges and systems utilizing microfluidic chips and cartridges |
| TWI591341B (zh) * | 2016-05-13 | 2017-07-11 | 亞諾法生技股份有限公司 | 微流道裝置 |
| US11602747B2 (en) | 2016-05-22 | 2023-03-14 | Cornell University | Multifunctional microfluidic device for capturing target cells and analyzing genomic DNA isolated from the target cells while under flow conditions |
| US10717086B2 (en) | 2016-08-29 | 2020-07-21 | The Regents Of The University Of California | Integrated system for isolation and emulsification of particles and cells |
| KR101872780B1 (ko) * | 2017-01-24 | 2018-06-29 | 광주과학기술원 | 헤링본 타입 유체유도유닛 및 이를 이용한 세포 농축 장치 |
| US10434510B2 (en) | 2017-05-06 | 2019-10-08 | International Business Machines Corporation | Microfluidic probe with bypass and control channels |
| WO2018213847A1 (en) * | 2017-05-19 | 2018-11-22 | The General Hospital Corporation | Engineered nano-interfaces for microfluidic isolation of extracellular vesicles |
| US10730042B2 (en) * | 2017-06-30 | 2020-08-04 | Ce Biotechnology, Inc. | Biological detection system |
| US11987780B2 (en) | 2017-07-14 | 2024-05-21 | Cedars-Sinai Medical Center | L-glass: a novel functionalization method for covalently attaching ECM protein to optical glass |
| CN108103022A (zh) | 2017-12-15 | 2018-06-01 | 京东方科技集团股份有限公司 | 一种目标物捕获装置 |
| CN108554326A (zh) * | 2018-03-02 | 2018-09-21 | 四川大学 | 一种用于c4烷基化反应的毫米级小通道反应器 |
| IT201800006083A1 (it) | 2018-06-06 | 2019-12-06 | Dispositivo microfluidico per la concentrazione di particelle tramite centrifugazione, e relativo dispositivo di centrifugazione e/o rilevazione | |
| KR102061979B1 (ko) | 2018-07-26 | 2020-01-02 | 재단법인 다차원 스마트 아이티 융합시스템 연구단 | 여과 처리량을 향상시킨 자유 침강 기반 미세유체 여과 시스템 및 방법 |
| WO2020113192A1 (en) | 2018-11-28 | 2020-06-04 | Cornell University | Systems and methods for on-chip analysis of nucleic acids and for multiplexed analysis of cells |
| US12338487B2 (en) | 2018-11-28 | 2025-06-24 | Cornell University | Multiomic analysis of cell analytes using microfluidic systems |
| JP7195538B2 (ja) * | 2019-03-15 | 2022-12-26 | 国立大学法人東海国立大学機構 | デバイスの製造方法、および、デバイス |
| US12053569B2 (en) * | 2019-09-04 | 2024-08-06 | The Regents Of The University Of Michigan | Indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells |
| EP4271793A1 (en) * | 2020-12-29 | 2023-11-08 | SQZ Biotechnologies Company | Microfluidic chip having increased throughput for use in a system for delivery of a payload into a cell |
| KR102765159B1 (ko) * | 2021-05-14 | 2025-02-11 | 연세대학교 산학협력단 | 헤링본 패턴 구조물을 포함하는 미세유체 칩 |
| US12576194B2 (en) | 2021-06-29 | 2026-03-17 | Regents Of The University Of Michigan | Microfluidic flow control using direct-current peristaltic pump |
| CN116024067A (zh) * | 2022-12-19 | 2023-04-28 | 深圳职业技术学院 | 一种循环胎儿细胞分离装置及其制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3788557A (en) | 1970-02-02 | 1974-01-29 | Spirolet Corp | Liquid injection adaptor |
| JP3618511B2 (ja) | 1997-04-14 | 2005-02-09 | オリンパス株式会社 | 微小流路素子 |
| US6692952B1 (en) | 1999-11-10 | 2004-02-17 | Massachusetts Institute Of Technology | Cell analysis and sorting apparatus for manipulation of cells |
| EP1307285A2 (en) * | 2000-08-03 | 2003-05-07 | Massachusetts Institute Of Technology | Microarrays of functional biomolecules, and uses therefor |
| US6531206B2 (en) * | 2001-02-07 | 2003-03-11 | 3M Innovative Properties Company | Microstructured surface film assembly for liquid acquisition and transport |
| WO2003015890A1 (en) * | 2001-08-20 | 2003-02-27 | President And Fellows Of Harvard College | Fluidic arrays and method of using |
| US6907895B2 (en) | 2001-09-19 | 2005-06-21 | The United States Of America As Represented By The Secretary Of Commerce | Method for microfluidic flow manipulation |
| US20030087292A1 (en) * | 2001-10-04 | 2003-05-08 | Shiping Chen | Methods and systems for promoting interactions between probes and target molecules in fluid in microarrays |
| US20030178641A1 (en) * | 2002-01-23 | 2003-09-25 | Blair Steven M. | Microfluidic platforms for use with specific binding assays, specific binding assays that employ microfluidics, and methods |
| US20040018611A1 (en) * | 2002-07-23 | 2004-01-29 | Ward Michael Dennis | Microfluidic devices for high gradient magnetic separation |
| WO2006095615A1 (ja) | 2005-03-07 | 2006-09-14 | Kuraray Co., Ltd. | マイクロチャネルアレイ及び製造方法、並びにこれを用いた血液測定方法 |
| JP5702909B2 (ja) * | 2005-03-23 | 2015-04-15 | ヴェロシス インコーポレイテッド | マイクロプロセス技術における表面機能構造部分 |
| WO2009012340A2 (en) * | 2007-07-16 | 2009-01-22 | California Institute Of Technology | Microfluidic devices, methods and systems for detecting target molecules |
| WO2009043057A2 (en) * | 2007-09-27 | 2009-04-02 | Massachusetts Institute Of Technology | Cell rolling separation |
| CN102227637A (zh) | 2008-09-26 | 2011-10-26 | 通用医疗公司 | 捕获粒子 |
-
2009
- 2009-09-25 CN CN2009801473137A patent/CN102227637A/zh active Pending
- 2009-09-25 US US13/121,130 patent/US9128091B2/en active Active
- 2009-09-25 WO PCT/US2009/058408 patent/WO2010036912A2/en not_active Ceased
- 2009-09-25 JP JP2011529270A patent/JP2012504243A/ja not_active Withdrawn
- 2009-09-25 BR BRPI0920868A patent/BRPI0920868A2/pt not_active Application Discontinuation
- 2009-09-25 EP EP09816915A patent/EP2344883A4/en not_active Withdrawn
-
2015
- 2015-09-02 US US14/843,028 patent/US10126218B2/en active Active
-
2018
- 2018-11-05 US US16/181,050 patent/US20190072465A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20150377753A1 (en) | 2015-12-31 |
| US20190072465A1 (en) | 2019-03-07 |
| CN102227637A (zh) | 2011-10-26 |
| US9128091B2 (en) | 2015-09-08 |
| EP2344883A4 (en) | 2012-03-21 |
| WO2010036912A2 (en) | 2010-04-01 |
| EP2344883A2 (en) | 2011-07-20 |
| US10126218B2 (en) | 2018-11-13 |
| US20110294187A1 (en) | 2011-12-01 |
| JP2012504243A (ja) | 2012-02-16 |
| WO2010036912A3 (en) | 2010-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |