BRPI0920870A2 - antibióticos de oxazolidinila. - Google Patents

antibióticos de oxazolidinila.

Info

Publication number
BRPI0920870A2
BRPI0920870A2 BRPI0920870A BRPI0920870A BRPI0920870A2 BR PI0920870 A2 BRPI0920870 A2 BR PI0920870A2 BR PI0920870 A BRPI0920870 A BR PI0920870A BR PI0920870 A BRPI0920870 A BR PI0920870A BR PI0920870 A2 BRPI0920870 A2 BR PI0920870A2
Authority
BR
Brazil
Prior art keywords
oxazolidinyl
antibiotics
oxazolidinyl antibiotics
Prior art date
Application number
BRPI0920870A
Other languages
English (en)
Inventor
Hubschwerlen Christian
Zumbrunn Acklin Cornelia
Rueedi Georg
Surivet Jean-Philippe
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of BRPI0920870A2 publication Critical patent/BRPI0920870A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BRPI0920870A 2008-10-10 2009-10-09 antibióticos de oxazolidinila. BRPI0920870A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2008054175 2008-10-10
PCT/IB2009/054433 WO2010041218A2 (en) 2008-10-10 2009-10-09 Oxazolidinyl antibiotics

Publications (1)

Publication Number Publication Date
BRPI0920870A2 true BRPI0920870A2 (pt) 2018-06-26

Family

ID=42101028

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0920870A BRPI0920870A2 (pt) 2008-10-10 2009-10-09 antibióticos de oxazolidinila.

Country Status (13)

Country Link
US (1) US8507478B2 (pt)
EP (1) EP2344485B1 (pt)
JP (1) JP5490809B2 (pt)
KR (1) KR101667066B1 (pt)
CN (1) CN102164919B (pt)
AU (1) AU2009302007B2 (pt)
BR (1) BRPI0920870A2 (pt)
CA (1) CA2739342C (pt)
ES (1) ES2628091T3 (pt)
MX (1) MX2011003188A (pt)
RU (1) RU2516701C2 (pt)
TW (1) TWI436999B (pt)
WO (1) WO2010041218A2 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR076222A1 (es) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
US8952010B2 (en) 2011-02-07 2015-02-10 Daiichi Sankyo Company, Limited Amino group-containing pyrrolidinone derivative
JP6030146B2 (ja) 2011-11-08 2016-11-24 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd 2−オキソ−オキサゾリジン−3,5−ジイル抗生物質誘導体
WO2014024056A1 (en) 2012-08-06 2014-02-13 Daiichi Sankyo Company, Limited Pyrrolidine derivatives with antibacterial properties
AR102256A1 (es) 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
RU2705183C1 (ru) * 2019-06-03 2019-11-05 Федеральное государственное бюджетное образовательное учреждение высшего образования "Санкт-Петербургский государственный химико-фармацевтический университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СПХФУ Минздрава России) 2-замещенные 5-гидроксипирано[2,3-d][1,3]оксазин-4,7-дионы и способ их получения
CN116615199A (zh) * 2020-11-26 2023-08-18 株式会社Lg化学 作为二酰基甘油激酶抑制剂的杂环化合物及其用途

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254682A (en) 1989-12-08 1993-10-19 Merck & Co., Inc. Cyclic renin inhibitors containing 3(S)-amino-4-cyclohexyl-2(R)-hydroxy-butanoic acid or 4-cyclo-hexyl-(2R, 3S)-dihydroxybutanoic acid or related analogs
DE19707628A1 (de) * 1997-02-26 1998-08-27 Merck Patent Gmbh Oxazolidinone
GB0031086D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
US6995162B2 (en) 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
EP1771456A2 (fr) * 2004-07-30 2007-04-11 Palumed SA Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
WO2006090272A1 (en) 2005-02-22 2006-08-31 Warner-Lambert Company Llc Isoquinoline [1,8]naphthyridin-2-ones and related compounds for treatment of schizophrenia
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
WO2006137485A1 (ja) 2005-06-24 2006-12-28 Toyama Chemical Co., Ltd. 新規な含窒素複素環化合物およびその塩
CN1763018B (zh) * 2005-09-30 2012-11-21 天津药物研究院 噁唑烷酮类化合物
MX2008014908A (es) * 2006-05-26 2009-05-13 Toyama Chemical Co Ltd Compuesto heterociclico nuevo o sal del mismo e intermedio del mismo.
EP2029612A1 (en) 2006-06-09 2009-03-04 Glaxo Group Limited Substituted 1-methyl-1h-quinolin-2-ones and 1-methyl-1h-1,5-naphthyridin-2-ones as antibacterials
ATE522514T1 (de) 2006-06-16 2011-09-15 Pharma Mar Sa Dihydropyran-2-onverbindungen mit antitumorwirkung
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
TW200819457A (en) 2006-08-30 2008-05-01 Actelion Pharmaceuticals Ltd Spiro antibiotic derivatives
ATE495743T1 (de) 2006-12-01 2011-02-15 Galapagos Nv Triazolopyridinverbindungen zur behandlung von degenerations- und entzündungskrankheiten
WO2008071964A1 (en) 2006-12-15 2008-06-19 Astrazeneca Ab Naphthyridine bactericides
WO2008071981A1 (en) 2006-12-15 2008-06-19 Astrazeneca Ab Piperidines for the treatment of bacterial infections
TW200831517A (en) 2006-12-15 2008-08-01 Astrazeneca Ab Chemical compounds
RU2492169C2 (ru) * 2007-12-18 2013-09-10 Актелион Фармасьютиклз Лтд Производные 5-аминоциклилметилоксазолидин-2-она
JP5404652B2 (ja) * 2008-02-22 2014-02-05 アクテリオン ファーマシューティカルズ リミテッド オキサゾリジノン誘導体

Also Published As

Publication number Publication date
TWI436999B (zh) 2014-05-11
US8507478B2 (en) 2013-08-13
US20110201595A1 (en) 2011-08-18
JP5490809B2 (ja) 2014-05-14
RU2516701C2 (ru) 2014-05-20
WO2010041218A2 (en) 2010-04-15
CN102164919B (zh) 2014-04-09
RU2011118497A (ru) 2012-11-20
AU2009302007A1 (en) 2010-04-15
AU2009302007B2 (en) 2015-01-15
KR101667066B1 (ko) 2016-10-17
CA2739342C (en) 2017-01-03
EP2344485A2 (en) 2011-07-20
MX2011003188A (es) 2011-04-27
WO2010041218A3 (en) 2010-10-14
JP2012505200A (ja) 2012-03-01
CN102164919A (zh) 2011-08-24
EP2344485B1 (en) 2017-03-22
TW201018687A (en) 2010-05-16
KR20110069141A (ko) 2011-06-22
CA2739342A1 (en) 2010-04-15
ES2628091T3 (es) 2017-08-01

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2483 DE 07-08-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]