BRPI0921244A2 - método para seletivamente cristalizar um isômero z da iopromida. - Google Patents

método para seletivamente cristalizar um isômero z da iopromida.

Info

Publication number: BRPI0921244A2
Authority: BR; Brazil
Prior art keywords: iopromide; isomer; selectively crystallizing; crystallizing; selectively
Prior art date: 2008-12-05

Application number

BRPI0921244A

Other languages

English (en)

Inventor

Lee Byung-Goo

Lee Han-Kuk

Lee Joon-Hwan

Choi Soo-Jin

Kim Wol-Young

Lim Young-Mook

Original Assignee

Dae Woong Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-12-05

Filing date

2009-10-12

Publication date

2018-06-26

2009-10-12 Application filed by Dae Woong Pharma filed Critical Dae Woong Pharma

2018-06-26 Publication of BRPI0921244A2 publication Critical patent/BRPI0921244A2/pt

Links

DGAIEPBNLOQYER-UHFFFAOYSA-N iopromide Chemical compound COCC(=O)NC1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)N(C)CC(O)CO)=C1I DGAIEPBNLOQYER-UHFFFAOYSA-N 0.000 title 1
229960002603 iopromide Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/68—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/69—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BRPI0921244A 2008-12-05 2009-10-12 método para seletivamente cristalizar um isômero z da iopromida. BRPI0921244A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
KR20080123138		2008-12-05
KR1020090085014A KR100976097B1 (ko)	2008-12-05	2009-09-09	이오프로마이드의 ｚ 이성체를 선택적으로 결정화하는 방법
PCT/KR2009/005827 WO2010064785A2 (en)	2008-12-05	2009-10-12	Method for selectively crystallizing a z isomer of iopromide

Publications (1)

Publication Number	Publication Date
BRPI0921244A2 true BRPI0921244A2 (pt)	2018-06-26

Family

ID=42364569

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0921244A BRPI0921244A2 (pt)	2008-12-05	2009-10-12	método para seletivamente cristalizar um isômero z da iopromida.

Country Status (10)

Country	Link
US (1)	US8541620B2 (pt)
EP (1)	EP2370396B1 (pt)
JP (1)	JP5411287B2 (pt)
KR (1)	KR100976097B1 (pt)
CN (1)	CN102239135B (pt)
BR (1)	BRPI0921244A2 (pt)
CA (1)	CA2744800C (pt)
MX (1)	MX2011005589A (pt)
RU (1)	RU2481325C2 (pt)
WO (1)	WO2010064785A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100976097B1 (ko) *	2008-12-05	2010-08-16	주식회사 대웅제약	이오프로마이드의 ｚ 이성체를 선택적으로 결정화하는 방법
KR102174436B1 (ko) *	2017-08-17	2020-11-04	주식회사 엘지화학	불용성 안료 화합물의 정성분석방법
CN116106431B (zh) *	2021-11-09	2024-10-11	北京北陆药业股份有限公司	利用高效液相色谱法分离碘普罗胺及相关杂质的分离及定量分析方法
CN116375597A (zh) *	2022-12-29	2023-07-04	江苏宇田医药有限公司	碘普罗胺无定型物及其制备方法
CN116041209A (zh) *	2022-12-29	2023-05-02	江苏宇田医药有限公司	碘普罗胺i型结晶及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2909439A1 (de) *	1979-03-08	1980-09-18	Schering Ag	Neue nichtionische roentgenkontrastmittel
IL110391A (en)	1993-07-30	1998-12-06	Zambon Spa	Process for the crystallization of iopamidol
GB9720969D0 (en) *	1997-10-02	1997-12-03	Nycomed Imaging As	Process
NO20053676D0 (no) *	2005-07-29	2005-07-29	Amersham Health As	Crystallisation Process
NO20053687D0 (no) *	2005-07-29	2005-07-29	Amersham Health As	Crystallisation Process.
JP2009518325A (ja) *	2005-12-05	2009-05-07	バイエル・シエーリング・ファーマアクチエンゲゼルシャフト	医薬目的のために適切なイオプロミドの母液からの回収方法
US7723544B2 (en) *	2005-12-08	2010-05-25	Bayer Schering Pharma Ag	Process for recovery of iopromide, suitable for pharmaceutical purposes, from mother liquors
KR101098553B1 (ko) *	2008-04-30	2011-12-26	주식회사 엘지생명과학	이오프로마이드의 신규한 제조방법
EP2365963B1 (en) *	2008-11-18	2017-06-28	Bracco Imaging S.p.A	Process for the preparation of iodinated contrast agent
KR100976097B1 (ko) *	2008-12-05	2010-08-16	주식회사 대웅제약	이오프로마이드의 ｚ 이성체를 선택적으로 결정화하는 방법

2009
- 2009-09-09 KR KR1020090085014A patent/KR100976097B1/ko not_active Expired - Fee Related
- 2009-10-12 CN CN200980148754.9A patent/CN102239135B/zh not_active Expired - Fee Related
- 2009-10-12 JP JP2011539442A patent/JP5411287B2/ja not_active Expired - Fee Related
- 2009-10-12 EP EP09830523.8A patent/EP2370396B1/en not_active Not-in-force
- 2009-10-12 BR BRPI0921244A patent/BRPI0921244A2/pt not_active Application Discontinuation
- 2009-10-12 CA CA2744800A patent/CA2744800C/en not_active Expired - Fee Related
- 2009-10-12 RU RU2011127392/04A patent/RU2481325C2/ru not_active IP Right Cessation
- 2009-10-12 WO PCT/KR2009/005827 patent/WO2010064785A2/en not_active Ceased
- 2009-10-21 US US13/132,791 patent/US8541620B2/en not_active Expired - Fee Related
- 2009-10-21 MX MX2011005589A patent/MX2011005589A/es unknown

Also Published As

Publication number	Publication date
EP2370396A2 (en)	2011-10-05
WO2010064785A3 (en)	2010-07-22
KR100976097B1 (ko)	2010-08-16
JP5411287B2 (ja)	2014-02-12
JP2012510510A (ja)	2012-05-10
MX2011005589A (es)	2011-07-20
EP2370396A4 (en)	2012-04-25
RU2481325C2 (ru)	2013-05-10
CN102239135B (zh)	2014-02-12
EP2370396B1 (en)	2019-02-20
WO2010064785A2 (en)	2010-06-10
CA2744800A1 (en)	2010-06-10
RU2011127392A (ru)	2013-01-10
US20110245347A1 (en)	2011-10-06
KR20100065064A (ko)	2010-06-15
US8541620B2 (en)	2013-09-24
CN102239135A (zh)	2011-11-09
CA2744800C (en)	2014-05-06

Legal Events

Date	Code	Title	Description
2018-09-18	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]	Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001
2019-01-22	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-12-03	B07G	Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
2020-03-03	B06U	Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
2020-09-01	B11B	Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
2021-08-24	B350	Update of information on the portal [chapter 15.35 patent gazette]

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BRPI0921882A2 (pt)	2015-12-29	processo para fabricar um composto.
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BRPI0921244A2 (pt)	2018-06-26	método para seletivamente cristalizar um isômero z da iopromida.
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