BRPI0921321A2 - métodos para o tratamento de indwcções e tumores - Google Patents

métodos para o tratamento de indwcções e tumores

Info

Publication number
BRPI0921321A2
BRPI0921321A2 BRPI0921321-0A BRPI0921321A BRPI0921321A2 BR PI0921321 A2 BRPI0921321 A2 BR PI0921321A2 BR PI0921321 A BRPI0921321 A BR PI0921321A BR PI0921321 A2 BRPI0921321 A2 BR PI0921321A2
Authority
BR
Brazil
Prior art keywords
tumors
treatment
methods
Prior art date
Application number
BRPI0921321-0A
Other languages
English (en)
Inventor
Ahmed Rafi
Amara Rama
Velu Vijayakumar
Titanji Kehmia
Freeman Gordon
Original Assignee
Emory University
Dana-Farber Cancer Institute Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emory University, Dana-Farber Cancer Institute Inc. filed Critical Emory University
Publication of BRPI0921321A2 publication Critical patent/BRPI0921321A2/pt

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    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/5052—Cells of the immune system involving B-cells
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • A—HUMAN NECESSITIES
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    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
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    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
BRPI0921321-0A 2008-11-28 2009-11-27 métodos para o tratamento de indwcções e tumores BRPI0921321A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11857008P 2008-11-28 2008-11-28
US61/118.570 2008-11-28
PCT/US2009/066023 WO2010063011A2 (en) 2008-11-28 2009-11-27 Methods for the treatment of infections and tumors

Publications (1)

Publication Number Publication Date
BRPI0921321A2 true BRPI0921321A2 (pt) 2018-10-16

Family

ID=42226387

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0921321-0A BRPI0921321A2 (pt) 2008-11-28 2009-11-27 métodos para o tratamento de indwcções e tumores

Country Status (14)

Country Link
US (3) US9598491B2 (pt)
EP (1) EP2370593B1 (pt)
JP (1) JP5520961B2 (pt)
KR (1) KR101721707B1 (pt)
CN (1) CN102282265B (pt)
AU (1) AU2009319701B2 (pt)
BR (1) BRPI0921321A2 (pt)
CA (1) CA2744449C (pt)
DK (1) DK2370593T3 (pt)
HU (1) HUE028582T2 (pt)
IL (1) IL213070A (pt)
MX (1) MX2011005691A (pt)
SI (1) SI2370593T1 (pt)
WO (1) WO2010063011A2 (pt)

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KR20110099109A (ko) 2011-09-06
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AU2009319701A1 (en) 2011-06-30
SI2370593T1 (sl) 2016-08-31
CA2744449A1 (en) 2010-06-03
EP2370593B1 (en) 2016-03-30
US20150239972A1 (en) 2015-08-27
AU2009319701B2 (en) 2014-10-09
US20170146520A1 (en) 2017-05-25
MX2011005691A (es) 2011-07-20
EP2370593A2 (en) 2011-10-05
IL213070A0 (en) 2011-07-31
JP2012510619A (ja) 2012-05-10
CN102282265A (zh) 2011-12-14
WO2010063011A3 (en) 2010-10-14
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US9598491B2 (en) 2017-03-21
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EP2370593A4 (en) 2012-09-05
DK2370593T3 (en) 2016-07-04
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US20100151492A1 (en) 2010-06-17
JP5520961B2 (ja) 2014-06-11

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