BRPI1003743A2 - Reagentes para testes de combinação antígeno-anticorpo do hcv - Google Patents

Reagentes para testes de combinação antígeno-anticorpo do hcv Download PDF

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Publication number
BRPI1003743A2
BRPI1003743A2 BRPI1003743-8A BRPI1003743A BRPI1003743A2 BR PI1003743 A2 BRPI1003743 A2 BR PI1003743A2 BR PI1003743 A BRPI1003743 A BR PI1003743A BR PI1003743 A2 BRPI1003743 A2 BR PI1003743A2
Authority
BR
Brazil
Prior art keywords
hcv
reagents
antigen
antibody combination
present
Prior art date
Application number
BRPI1003743-8A
Other languages
English (en)
Inventor
Zheng Jian
Yang Jianping
Original Assignee
Ortho-Clinical Diagnostics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Clinical Diagnostics, Inc. filed Critical Ortho-Clinical Diagnostics, Inc.
Publication of BRPI1003743A2 publication Critical patent/BRPI1003743A2/pt

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
    • G01N2333/186—Hepatitis C; Hepatitis NANB
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)

Abstract

REAGENTES PARA TESTES DE COMBINAçãO ANTìGENO-ANTICORPO DO HCV. A presente invenção refere-se a imunoensaios de combinação, a reagentes e a kits para detecção simultânea de antígenos do HCV e de anticorpos anti-HCV em uma amostra. Os imunoensaios de combinação da presente invenção empregam um detergente não-iónico que efetivamente expõe ou libera o antígeno central do HCV a partir de vírions presentes em uma amostra sem interferir com o desempenho de outros reagentes, como a captura de anticorpos anti-HCV por antígenos do HCV recombinantes.
BRPI1003743-8A 2009-05-20 2010-05-19 Reagentes para testes de combinação antígeno-anticorpo do hcv BRPI1003743A2 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/469,568 US20100297607A1 (en) 2009-05-20 2009-05-20 Reagents For HCV Antigen-Antibody Combination Assays

Publications (1)

Publication Number Publication Date
BRPI1003743A2 true BRPI1003743A2 (pt) 2012-03-20

Family

ID=42558582

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1003743-8A BRPI1003743A2 (pt) 2009-05-20 2010-05-19 Reagentes para testes de combinação antígeno-anticorpo do hcv

Country Status (8)

Country Link
US (3) US20100297607A1 (pt)
EP (1) EP2259066B1 (pt)
JP (1) JP5836569B2 (pt)
KR (1) KR101828767B1 (pt)
BR (1) BRPI1003743A2 (pt)
CA (1) CA2704458A1 (pt)
ES (1) ES2443591T3 (pt)
RU (1) RU2010120136A (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2688268T3 (es) * 2011-12-05 2018-10-31 Bio-Rad Laboratories, Inc. Antígeno de gliadina desamidada recombinante
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
EP2970947A4 (en) 2013-03-14 2016-10-12 Abbott Lab RECOMBINANT HCV NS3 ANTIGENS AND THEIR MUTANTS FOR ENHANCED ANTIBODY DETECTION
JP6505076B2 (ja) 2013-03-14 2019-04-24 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ Ｈｃｖ抗原−抗体組み合わせアッセイおよびこれに使用するための方法および組成物
CN105378099B (zh) 2013-03-14 2021-05-11 雅培制药有限公司 Hcv核心脂质结合结构域单克隆抗体
CN103630690B (zh) * 2013-12-17 2014-08-20 朱之炜 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法
US20170242010A1 (en) * 2014-02-11 2017-08-24 The Regents Of The University Of California Combo-Hepatitis Antigen Assays and Kits for Detection of Active Hepatitis Virus Infections
EP3274478B1 (en) * 2015-03-27 2020-09-23 Ortho-Clinical Diagnostics, Inc. Hcv ns4a/modified ns3 polypeptides and uses thereof
CN106093402A (zh) * 2016-05-31 2016-11-09 湖南康润药业有限公司 丙型肝炎病毒抗原抗体联合检测试剂盒
CN110261616B (zh) * 2019-04-30 2021-07-20 广东菲鹏生物有限公司 一种丙型肝炎病毒检测试剂盒
BE1027715B1 (fr) * 2020-04-08 2021-05-26 Coris Bioconcept Sprl Methode et test immunodiagnostiques rapides de l' infection covid-19

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870003A (en) * 1987-06-15 1989-09-26 Coulter Corporation Simultaneous enzyme immunoassay for detecting antigen and/or antibody in humans
US5447837A (en) * 1987-08-05 1995-09-05 Calypte, Inc. Multi-immunoassay diagnostic system for antigens or antibodies or both
US6171782B1 (en) * 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
CA1335880C (en) * 1988-07-14 1995-06-13 Thomas P. O'connor Detection of an antibody and antigen in an immunoassay
GB9211686D0 (en) 1992-06-03 1992-07-15 Medisinsk Innovation A S Chemical compounds
US5763158A (en) * 1997-02-06 1998-06-09 The United States Of America As Represented By The Secretary Of The Army Detection of multiple antigens or antibodies
FR2760367B1 (fr) * 1997-03-06 1999-04-30 Pasteur Merieux Serums Vacc Composition vaccinale destinee a la prevention ou au traitement des hepatites c
ES2187947T5 (es) * 1997-03-10 2014-01-29 Roche Diagnostics Gmbh Procedimiento para la detección simultánea de antígenos de HIV y anticuerpos de HIV
KR100523685B1 (ko) 1997-08-04 2005-10-26 가부시끼가이샤 센탈 세메 가가꾸 겐꾸쇼 Ｃ형 간염 바이러스의 코어 영역의 아미노산 서열을 인지하는 모노클로날 항체
WO1999058561A1 (fr) 1998-05-14 1999-11-18 Pasteur Merieux Serums & Vaccins Mimotopes du virus de l'hepatite c
US6623921B2 (en) * 1998-07-30 2003-09-23 Advanced Life Science Institute, Inc. Method for measurement of hepatitis C virus
US20020037868A1 (en) * 1999-04-14 2002-03-28 Institut Pasteur Method for detecting hepatitis C
US6383740B2 (en) * 1999-07-30 2002-05-07 Bioergonomics, Inc. Methods for simultaneously detecting both members of a binding pair
SK287694B6 (sk) 2000-06-15 2011-06-06 Novartis Vaccines & Diagnostics, Inc. Pevný nosič imunoeseje a spôsob jeho prípravy, spôsob detekcie infekcie HIV a súprava na imunodiagnostickú skúšku
AU785380B2 (en) 2001-03-28 2007-03-15 Ortho-Clinical Diagnostics, Inc. A hepatitis C antigen - antibody combination assay for the early detection of HCV infection
US7101683B2 (en) * 2001-06-26 2006-09-05 Abbott Laboratories Methods for the simultaneous detection of HCV antigens and HCV antibodies
JP4353793B2 (ja) * 2001-06-26 2009-10-28 アボット・ラボラトリーズ Ｈｃｖ抗原とｈｃｖ抗体との同時検出のための方法
US20030108563A1 (en) * 2001-11-07 2003-06-12 Chander Bahl Reagents for the simultaneous detection of HCV core antigens and antibodies
FR2839555B1 (fr) 2002-05-10 2007-07-27 Bio Rad Pasteur Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux
US20040152070A1 (en) 2003-02-04 2004-08-05 Shah Dinesh O. Method of detection of HCV antibodies in combination assay or sole antibody assay

Also Published As

Publication number Publication date
JP5836569B2 (ja) 2015-12-24
US20100297607A1 (en) 2010-11-25
KR101828767B1 (ko) 2018-02-13
EP2259066B1 (en) 2013-11-13
KR20100125194A (ko) 2010-11-30
RU2010120136A (ru) 2011-11-27
US10041946B2 (en) 2018-08-07
ES2443591T3 (es) 2014-02-19
US9915658B2 (en) 2018-03-13
JP2010271313A (ja) 2010-12-02
US20180156799A1 (en) 2018-06-07
US20160109447A1 (en) 2016-04-21
CA2704458A1 (en) 2010-11-20
EP2259066A1 (en) 2010-12-08

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Legal Events

Date Code Title Description
B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.