BRPI1005702B1 - método para aumentar a taxa de implantação de embriões no útero materno em mamíferos, uso de uma quantidade eficaz de uma lectina ligante de beta-galactosídeo ou derivados da mesma e produto - Google Patents

método para aumentar a taxa de implantação de embriões no útero materno em mamíferos, uso de uma quantidade eficaz de uma lectina ligante de beta-galactosídeo ou derivados da mesma e produto Download PDF

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Publication number
BRPI1005702B1
BRPI1005702B1 BRPI1005702A BRPI1005702A BRPI1005702B1 BR PI1005702 B1 BRPI1005702 B1 BR PI1005702B1 BR PI1005702 A BRPI1005702 A BR PI1005702A BR PI1005702 A BRPI1005702 A BR PI1005702A BR PI1005702 B1 BRPI1005702 B1 BR PI1005702B1
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Brazil
Prior art keywords
embryo
derivatives
galectin
galactoside
beta
Prior art date
Application number
BRPI1005702A
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English (en)
Portuguese (pt)
Inventor
Del Cistia Andrade Camillo
Da Silva Carvalho Morani Erika
Cataldi Rodrigues Lílian
Dias Baruffi Marcelo
Roncoletta Marcelo
Original Assignee
Inprenha Biotecnologia E Desenvolvimento Avancado Ltda Me
Univ Sao Paulo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Inprenha Biotecnologia E Desenvolvimento Avancado Ltda Me, Univ Sao Paulo filed Critical Inprenha Biotecnologia E Desenvolvimento Avancado Ltda Me
Priority to BRPI1005702A priority Critical patent/BRPI1005702B1/pt
Priority to CN201180068131.8A priority patent/CN103702720B/zh
Priority to JP2013544976A priority patent/JP6120374B2/ja
Priority to PCT/BR2011/000454 priority patent/WO2012083396A1/en
Priority to PL11805370T priority patent/PL2654897T3/pl
Priority to RU2013133832A priority patent/RU2631598C2/ru
Priority to ES11805370T priority patent/ES2756773T3/es
Priority to EP11805370.1A priority patent/EP2654897B1/en
Priority to CN201811493360.4A priority patent/CN109966474A/zh
Priority to US13/996,920 priority patent/US9637533B2/en
Priority to PT118053701T priority patent/PT2654897T/pt
Priority to EP19189687.7A priority patent/EP3623008A1/en
Publication of BRPI1005702A2 publication Critical patent/BRPI1005702A2/pt
Priority to ZA2013/04626A priority patent/ZA201304626B/en
Priority to JP2017000467A priority patent/JP2017081976A/ja
Priority to JP2018186468A priority patent/JP6673998B2/ja
Publication of BRPI1005702B1 publication Critical patent/BRPI1005702B1/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056Lectin superfamily, e.g. CD23, CD72
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1732Lectins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/178Lectin superfamily, e.g. selectins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726Lectins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
BRPI1005702A 2010-12-21 2010-12-21 método para aumentar a taxa de implantação de embriões no útero materno em mamíferos, uso de uma quantidade eficaz de uma lectina ligante de beta-galactosídeo ou derivados da mesma e produto BRPI1005702B1 (pt)

Priority Applications (15)

Application Number Priority Date Filing Date Title
BRPI1005702A BRPI1005702B1 (pt) 2010-12-21 2010-12-21 método para aumentar a taxa de implantação de embriões no útero materno em mamíferos, uso de uma quantidade eficaz de uma lectina ligante de beta-galactosídeo ou derivados da mesma e produto
EP11805370.1A EP2654897B1 (en) 2010-12-21 2011-12-09 Method for increasing embryo implantation rate in mother's uterus in mammals, use of an effective amount of beta-galactoside-binding lectin or derivatives thereof, beta-galactoside-binding lectin or derivatives and product
CN201811493360.4A CN109966474A (zh) 2010-12-21 2011-12-09 用于在哺乳动物中增加母体子宫的胚胎植入率的方法
PCT/BR2011/000454 WO2012083396A1 (en) 2010-12-21 2011-12-09 Method for increasing embryo implantation rate in mother's uterus in mammals, use of an effective amount of beta - galactoside - binding lectin or derivatives thereof, beta - galactoside - binding lectin or derivatives and product.
PL11805370T PL2654897T3 (pl) 2010-12-21 2011-12-09 Sposób zwiększania tempa implantacji zarodka w macicy matki u ssaków, zastosowanie skutecznej ilości lektyny wiążącej betagalaktozyd lub jej pochodnych, lektyna wiążąca betagalaktozyd lub pochodne i produkt
RU2013133832A RU2631598C2 (ru) 2010-12-21 2011-12-09 Способ повышения частоты имплантации эмбриона в материнской матке млекопитающих, применение эффективного количества бета-галактозид-связывающего лектина или его производных, бета-галактозид-связывающий лектин или производные и продукт
ES11805370T ES2756773T3 (es) 2010-12-21 2011-12-09 Método para aumentar el índice de implantación del embrión en el útero de la madre en mamíferos, uso de una cantidad eficaz de lectina de unión al beta-galactósido o de derivados de la misma, de lectina de unión al beta-galactósido o de derivados y producto
CN201180068131.8A CN103702720B (zh) 2010-12-21 2011-12-09 用于在哺乳动物中增加母体子宫的胚胎植入率的方法
JP2013544976A JP6120374B2 (ja) 2010-12-21 2011-12-09 哺乳動物の母親の子宮における着床率を増加させる方法、有効量のベータ−ガラクトシド結合レクチンまたはその誘導体の使用、ベータ−ガラクトシド結合レクチンまたは誘導体および製品
US13/996,920 US9637533B2 (en) 2010-12-21 2011-12-09 Methods for increasing the embryo implantation rate in mammals
PT118053701T PT2654897T (pt) 2010-12-21 2011-12-09 Método para aumentar a taxa de implantação de embriões no útero da progenitora em mamíferos, utilização de uma quantidade eficaz de lectina de ligação a beta-galactósido ou seus derivados, lectina de ligação a beta-galactósido ou derivados e produto
EP19189687.7A EP3623008A1 (en) 2010-12-21 2011-12-09 Method for increasing embryo implantation rate in mother's uterus in mammals, use of an effective amount of beta-galactoside -binding lectin or derivatives thereof, beta-galactoside-binding lectin or derivatives and product
ZA2013/04626A ZA201304626B (en) 2010-12-21 2013-06-21 Method for increasing embryo implantation in mother's uterus in mammals,use of an effective amount of beta-galactoside-binding lectin or derivatives thereof,beta-galactoside-binding lectin or derivatives and product
JP2017000467A JP2017081976A (ja) 2010-12-21 2017-01-05 哺乳動物の母親の子宮における着床率を増加させる方法、有効量のベータ−ガラクトシド結合レクチンまたはその誘導体の使用、ベータ−ガラクトシド結合レクチンまたは誘導体および製品
JP2018186468A JP6673998B2 (ja) 2010-12-21 2018-10-01 哺乳動物の母親の子宮における着床率を増加させる方法、有効量のベータ−ガラクトシド結合レクチンまたはその誘導体の使用、ベータ−ガラクトシド結合レクチンまたは誘導体および製品

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI1005702A BRPI1005702B1 (pt) 2010-12-21 2010-12-21 método para aumentar a taxa de implantação de embriões no útero materno em mamíferos, uso de uma quantidade eficaz de uma lectina ligante de beta-galactosídeo ou derivados da mesma e produto

Publications (2)

Publication Number Publication Date
BRPI1005702A2 BRPI1005702A2 (pt) 2013-04-02
BRPI1005702B1 true BRPI1005702B1 (pt) 2020-02-04

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1005702A BRPI1005702B1 (pt) 2010-12-21 2010-12-21 método para aumentar a taxa de implantação de embriões no útero materno em mamíferos, uso de uma quantidade eficaz de uma lectina ligante de beta-galactosídeo ou derivados da mesma e produto

Country Status (11)

Country Link
US (1) US9637533B2 (pl)
EP (2) EP3623008A1 (pl)
JP (3) JP6120374B2 (pl)
CN (2) CN103702720B (pl)
BR (1) BRPI1005702B1 (pl)
ES (1) ES2756773T3 (pl)
PL (1) PL2654897T3 (pl)
PT (1) PT2654897T (pl)
RU (1) RU2631598C2 (pl)
WO (1) WO2012083396A1 (pl)
ZA (1) ZA201304626B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI1005702B1 (pt) 2010-12-21 2020-02-04 Inprenha Biotecnologia E Desenvolvimento Avancado Ltda Me método para aumentar a taxa de implantação de embriões no útero materno em mamíferos, uso de uma quantidade eficaz de uma lectina ligante de beta-galactosídeo ou derivados da mesma e produto
JP2020514772A (ja) * 2017-01-15 2020-05-21 アレックス・ライフ・サイエンシーズ・リミテッド・ライアビリティ・カンパニーArex Life Sciences Llc 人工授精における受精能を改善する方法
CA3155035C (en) 2019-10-29 2024-06-04 William Alan BLAIR Apparatus to facilitate transfer of biological specimens stored at cryogenic conditions
US11817187B2 (en) * 2020-05-18 2023-11-14 TMRW Life Sciences, Inc. Handling and tracking of biological specimens for cryogenic storage
CN111658223A (zh) * 2020-06-11 2020-09-15 上海滔华生物医药科技合伙企业(有限合伙) 一种受体牛的筛选方法
JP7610303B2 (ja) 2020-09-24 2025-01-08 ティーエムアールダブリュ ライフサイエンシーズ,インコーポレイテツド 極低温条件で保管された生物学的試料の移送を容易にするためのワークステーション及び装置
US12099890B2 (en) 2020-10-02 2024-09-24 TMRW Life Sciences, Inc. Interrogation device and/or system having alignment feature(s) for wireless transponder tagged specimen containers and/or carriers
CA3200508A1 (en) 2020-12-10 2022-06-16 TMRW Life Sciences, Inc. Specimen holder with wireless transponder for attachment to specimen collection body
EP4252009B1 (en) 2021-01-13 2025-03-05 TMRW Life Sciences, Inc. System to pick and/or place specimen containers
EP4412453A4 (en) 2021-10-08 2025-01-22 TMRW Life Sciences, Inc. SYSTEMS, DEVICES AND METHODS FOR TAKING AND/OR PLACING SAMPLE CONTAINERS

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US5869081A (en) * 1996-06-28 1999-02-09 The Population Council Progesterone vaginal ring for treatment of infertility
WO2000032140A1 (en) * 1998-11-30 2000-06-08 Ivf Sciences Colorado, Inc. System and sequential culture media for in vitro fertilization
WO2001065928A1 (en) * 2000-03-09 2001-09-13 Yves Chicheportiche A method for increasing the in vitro production of cystic embryoid bodies from mammalian embryonic stem cells
RU2272630C2 (ru) * 2004-04-28 2006-03-27 ФГОУ ВПО "Курская государственная сельскохозяйственная академия им. проф. И.И. Иванова" Способ повышения выживаемости эмбрионов у коров
US20070185014A1 (en) 2006-02-09 2007-08-09 The Schepens Eye Research Institute, Inc. Methods and compositions for modulating conjunctival goblet cells
EP1908476A1 (en) 2006-09-28 2008-04-09 Charite-Universitätsmedizin Berlin Galectin-2 for the treatment of inflammatory diseases of the skin
US20120178331A1 (en) * 2010-10-21 2012-07-12 Eastman Chemical Company Nonwoven article with ribbon fibers
BRPI1005702B1 (pt) 2010-12-21 2020-02-04 Inprenha Biotecnologia E Desenvolvimento Avancado Ltda Me método para aumentar a taxa de implantação de embriões no útero materno em mamíferos, uso de uma quantidade eficaz de uma lectina ligante de beta-galactosídeo ou derivados da mesma e produto

Also Published As

Publication number Publication date
JP2014500279A (ja) 2014-01-09
EP2654897A1 (en) 2013-10-30
BRPI1005702A2 (pt) 2013-04-02
CN109966474A (zh) 2019-07-05
JP6673998B2 (ja) 2020-04-01
RU2631598C2 (ru) 2017-09-25
JP2017081976A (ja) 2017-05-18
US9637533B2 (en) 2017-05-02
PT2654897T (pt) 2019-12-02
RU2013133832A (ru) 2015-01-27
CN103702720A (zh) 2014-04-02
ZA201304626B (en) 2014-09-25
JP2019023208A (ja) 2019-02-14
ES2756773T3 (es) 2020-04-27
EP3623008A1 (en) 2020-03-18
CN103702720B (zh) 2020-07-07
US20140057858A1 (en) 2014-02-27
EP2654897B1 (en) 2019-08-21
WO2012083396A1 (en) 2012-06-28
JP6120374B2 (ja) 2017-04-26
PL2654897T3 (pl) 2020-05-18

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
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Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/12/2010, OBSERVADAS AS CONDICOES LEGAIS.