BRPI1005932A2 - composto, composição farmacêutica para inalação e inalador - Google Patents

composto, composição farmacêutica para inalação e inalador

Info

Publication number: BRPI1005932A2
Authority: BR; Brazil
Prior art keywords: inhaler; inhalation; compound; pharmaceutical composition; pharmaceutical
Prior art date: 2009-02-18

Application number

BRPI1005932A

Other languages

English (en)

Inventor

Massana Montejo Eric

Ruf Thorsten

Original Assignee

Almirall Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-02-18

Filing date

2010-02-18

Publication date

2017-05-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40848429&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1005932(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2010-02-18 Application filed by Almirall Sa filed Critical Almirall Sa

2017-05-02 Publication of BRPI1005932A2 publication Critical patent/BRPI1005932A2/pt

Links

150000001875 compounds Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biophysics (AREA)
Anesthesiology (AREA)
Hematology (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BRPI1005932A 2009-02-18 2010-02-18 composto, composição farmacêutica para inalação e inalador BRPI1005932A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP09382021A EP2221297A1 (en)	2009-02-18	2009-02-18	5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases
PCT/EP2010/001027 WO2010094484A1 (en)	2009-02-18	2010-02-18	5- (2-{ [6- (2, 2-difluoro-2-phenylethoxy) hexyl] amino}-l-hydroxyethyl) -8-hydroxyquin olin-2 (1h)-one and its use in the treatment of pulmonary diseases

Publications (1)

Publication Number	Publication Date
BRPI1005932A2 true BRPI1005932A2 (pt)	2017-05-02

Family

ID=40848429

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI1005932A BRPI1005932A2 (pt)	2009-02-18	2010-02-18	composto, composição farmacêutica para inalação e inalador

Country Status (22)

Country	Link
US (2)	US20120040941A1 (pt)
EP (2)	EP2221297A1 (pt)
JP (2)	JP2012518020A (pt)
KR (1)	KR20110123740A (pt)
CN (2)	CN102317264A (pt)
AR (1)	AR075769A1 (pt)
AU (1)	AU2010214855A1 (pt)
BR (1)	BRPI1005932A2 (pt)
CA (1)	CA2749045A1 (pt)
CL (2)	CL2011002002A1 (pt)
CO (1)	CO6361996A2 (pt)
EA (1)	EA201101211A1 (pt)
EC (1)	ECSP11011337A (pt)
IL (1)	IL213980A0 (pt)
MX (1)	MX2011008573A (pt)
PE (1)	PE20120420A1 (pt)
PH (1)	PH12014500417A1 (pt)
SG (2)	SG2014009872A (pt)
TW (1)	TW201031409A (pt)
UY (1)	UY32435A (pt)
WO (1)	WO2010094484A1 (pt)
ZA (1)	ZA201104655B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2265276B1 (es)	2005-05-20	2008-02-01	Laboratorios Almirall S.A.	Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
ES2302447B1 (es) *	2006-10-20	2009-06-12	Laboratorios Almirall S.A.	Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
ES2306595B1 (es) *	2007-02-09	2009-09-11	Laboratorios Almirall S.A.	Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.
UY32297A (es)	2008-12-22	2010-05-31	Almirall Sa	Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
EP2228368A1 (en)	2009-03-12	2010-09-15	Almirall, S.A.	Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
EP2578570A1 (en)	2011-10-07	2013-04-10	Almirall, S.A.	Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2641900A1 (en)	2012-03-20	2013-09-25	Almirall, S.A.	Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
EP2668941A1 (en) *	2012-05-31	2013-12-04	Almirall, S.A.	Novel dosage form and formulation of abediterol

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT7920688U1 (it)	1979-02-05	1980-08-05	Chiesi Paolo	Inalatore per sostanze medicamentose pulverulente, con combinata funzione di dosatore
ATE23272T1 (de)	1981-07-08	1986-11-15	Draco Ab	Pulverinhalator.
US4570630A (en)	1983-08-03	1986-02-18	Miles Laboratories, Inc.	Medicament inhalation device
FI69963C (fi)	1984-10-04	1986-09-12	Orion Yhtymae Oy	Doseringsanordning
DE3927170A1 (de)	1989-08-17	1991-02-21	Boehringer Ingelheim Kg	Inhalator
IT1237118B (it)	1989-10-27	1993-05-18	Miat Spa	Inalatore multidose per farmaci in polvere.
GB9004781D0 (en)	1990-03-02	1990-04-25	Glaxo Group Ltd	Device
SG45171A1 (en)	1990-03-21	1998-01-16	Boehringer Ingelheim Int	Atomising devices and methods
GB9015522D0 (en)	1990-07-13	1990-08-29	Braithwaite Philip W	Inhaler
WO1992003175A1 (en)	1990-08-11	1992-03-05	Fisons Plc	Inhalation device
DE4027391A1 (de)	1990-08-30	1992-03-12	Boehringer Ingelheim Kg	Treibgasfreies inhalationsgeraet
ATE209938T1 (de)	1990-09-26	2001-12-15	Pharmachemie Bv	Wirbelkammer-pulverinhalator
GB9026025D0 (en)	1990-11-29	1991-01-16	Boehringer Ingelheim Kg	Inhalation device
AU650953B2 (en)	1991-03-21	1994-07-07	Novartis Ag	Inhaler
DE4239402A1 (de)	1992-11-24	1994-05-26	Bayer Ag	Pulverinhalator
PL173090B1 (pl)	1992-12-18	1998-01-30	Schering Corp	Inhalator do sproszkowanych lekarstw
MX9707864A (es)	1995-04-14	1997-11-29	Glaxo Wellcome Inc	Inhalador de dosis medida por salmeterol.
CA2378713C (en)	1995-06-21	2003-08-12	Asta Medica Aktiengesellschaft	Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments
DE19536902A1 (de)	1995-10-04	1997-04-10	Boehringer Ingelheim Int	Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
DE10129703A1 (de)	2001-06-22	2003-01-02	Sofotec Gmbh & Co Kg	Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren
DE10202940A1 (de)	2002-01-24	2003-07-31	Sofotec Gmbh & Co Kg	Patrone für einen Pulverinhalator
ES2195785B1 (es)	2002-05-16	2005-03-16	Almirall Prodesfarma, S.A.	Nuevos derivados de piridazin-3(2h)-ona.
ES2211344B1 (es)	2002-12-26	2005-10-01	Almirall Prodesfarma, S.A.	Nuevos derivados de piridazin-3(2h)-ona.
ES2232306B1 (es)	2003-11-10	2006-08-01	Almirall Prodesfarma, S.A.	Nuevos derivados de piridazin-3(2h)-ona.
ES2251866B1 (es)	2004-06-18	2007-06-16	Laboratorios Almirall S.A.	Nuevos derivados de piridazin-3(2h)-ona.
ES2251867B1 (es)	2004-06-21	2007-06-16	Laboratorios Almirall S.A.	Nuevos derivados de piridazin-3(2h)-ona.
ES2265276B1 (es)	2005-05-20	2008-02-01	Laboratorios Almirall S.A.	Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
ES2306595B1 (es)	2007-02-09	2009-09-11	Laboratorios Almirall S.A.	Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.

2009
- 2009-02-18 EP EP09382021A patent/EP2221297A1/en not_active Withdrawn
2010
- 2010-02-10 UY UY0001032435A patent/UY32435A/es unknown
- 2010-02-12 TW TW099104707A patent/TW201031409A/zh unknown
- 2010-02-17 AR ARP100100454A patent/AR075769A1/es unknown
- 2010-02-18 KR KR1020117018646A patent/KR20110123740A/ko not_active Ceased
- 2010-02-18 WO PCT/EP2010/001027 patent/WO2010094484A1/en not_active Ceased
- 2010-02-18 BR BRPI1005932A patent/BRPI1005932A2/pt not_active IP Right Cessation
- 2010-02-18 AU AU2010214855A patent/AU2010214855A1/en not_active Abandoned
- 2010-02-18 SG SG2014009872A patent/SG2014009872A/en unknown
- 2010-02-18 JP JP2011550475A patent/JP2012518020A/ja active Pending
- 2010-02-18 US US13/202,020 patent/US20120040941A1/en not_active Abandoned
- 2010-02-18 CN CN2010800082336A patent/CN102317264A/zh active Pending
- 2010-02-18 EA EA201101211A patent/EA201101211A1/ru unknown
- 2010-02-18 PE PE2011001310A patent/PE20120420A1/es not_active Application Discontinuation
- 2010-02-18 SG SG2011052826A patent/SG173092A1/en unknown
- 2010-02-18 MX MX2011008573A patent/MX2011008573A/es not_active Application Discontinuation
- 2010-02-18 EP EP10709683A patent/EP2398772A1/en not_active Withdrawn
- 2010-02-18 CN CN2013102471118A patent/CN103288729A/zh active Pending
- 2010-02-18 CA CA2749045A patent/CA2749045A1/en not_active Abandoned
2011
- 2011-06-23 ZA ZA2011/04655A patent/ZA201104655B/en unknown
- 2011-07-07 IL IL213980A patent/IL213980A0/en unknown
- 2011-08-12 CO CO11102789A patent/CO6361996A2/es not_active Application Discontinuation
- 2011-08-17 CL CL2011002002A patent/CL2011002002A1/es unknown
- 2011-09-16 EC EC2011011337A patent/ECSP11011337A/es unknown
2013
- 2013-10-08 US US14/048,344 patent/US20140038928A1/en not_active Abandoned
2014
- 2014-02-21 PH PH12014500417A patent/PH12014500417A1/en unknown
- 2014-03-04 CL CL2014000531A patent/CL2014000531A1/es unknown
- 2014-08-15 JP JP2014165548A patent/JP2015028029A/ja active Pending

Also Published As

Publication number	Publication date
AU2010214855A1 (en)	2011-07-21
CA2749045A1 (en)	2010-08-26
JP2015028029A (ja)	2015-02-12
EP2221297A1 (en)	2010-08-25
KR20110123740A (ko)	2011-11-15
US20140038928A1 (en)	2014-02-06
EP2398772A1 (en)	2011-12-28
CL2014000531A1 (es)	2014-09-05
ECSP11011337A (es)	2011-10-31
CN103288729A (zh)	2013-09-11
SG173092A1 (en)	2011-08-29
US20120040941A1 (en)	2012-02-16
UY32435A (es)	2010-05-31
CO6361996A2 (es)	2012-01-20
PH12014500417A1 (en)	2015-10-19
TW201031409A (en)	2010-09-01
EA201101211A1 (ru)	2012-03-30
MX2011008573A (es)	2011-09-06
JP2012518020A (ja)	2012-08-09
ZA201104655B (en)	2012-02-29
SG2014009872A (en)	2014-04-28
CL2011002002A1 (es)	2011-11-11
CN102317264A (zh)	2012-01-11
IL213980A0 (en)	2011-08-31
PE20120420A1 (es)	2012-05-09
WO2010094484A1 (en)	2010-08-26
AR075769A1 (es)	2011-04-27

Legal Events

Date	Code	Title
2017-05-23	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2017-09-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
2021-07-13	B350	Update of information on the portal [chapter 15.35 patent gazette]

Publication	Publication Date	Title
BRPI1008598A2 (pt)	2016-03-15	composição farmacêutica para inalação
DK2461857T3 (da)	2019-10-28	Inhalator
BRPI0814536A2 (pt)	2015-01-27	Inalador para pó
DK2114498T3 (da)	2014-09-01	Inhalator
DK3108966T3 (da)	2020-01-02	Inhalator
DK2440271T3 (da)	2014-09-01	Inhalator
DK2708255T3 (da)	2015-06-22	Inhalator
DK2326374T3 (da)	2020-05-18	Inhalator
HUE042291T2 (hu)	2019-06-28	Dózis számlálók inhalátorokhoz
DK2488242T3 (da)	2019-12-02	Medicinsk indåndingsmaske
IT1395945B1 (it)	2012-11-02	Inalatore perfezionato per preparati in polvere
BRPI0906366A2 (pt)	2015-07-07	Inalador
EP2542285C0 (en)	2023-10-11	INHALER
SG11201400580VA (en)	2014-05-29	Pharmaceutical composition for inhalation
BRPI0906779A2 (pt)	2015-07-14	Inalador
BR112012000831A2 (pt)	2019-09-24	compostos, composições farmacêuticas e métodos relacionados
BRPI1005932A2 (pt)	2017-05-02	composto, composição farmacêutica para inalação e inalador
BRPI1007484A2 (pt)	2016-02-16	composição farmacêutica para administração oral
BRPI0906367A2 (pt)	2016-04-26	inalador
BRPI0920390A2 (pt)	2019-09-24	inalador ativado por respiração
DK2129422T3 (da)	2013-05-13	Doseringsinhalator
SMT201500005B (it)	2015-05-05	Composizione framaceutica inalabile
BRPI0814248A2 (pt)	2015-01-06	Inalador
PL2504331T3 (pl)	2015-04-30	Związek, jego nowe formy, zawierające je kompozycje farmaceutyczne i sposoby otrzymywania oraz zastosowanie
BRPI0906369A2 (pt)	2015-07-07	Inalador