BRPI1009860A8 - composto, uso do mesmo, composição farmacêutica e método para tratamento terapêutico ou prevenção de doenças em humanos ou animais - Google Patents
composto, uso do mesmo, composição farmacêutica e método para tratamento terapêutico ou prevenção de doenças em humanos ou animais Download PDFInfo
- Publication number
- BRPI1009860A8 BRPI1009860A8 BRPI1009860A BRPI1009860A BRPI1009860A8 BR PI1009860 A8 BRPI1009860 A8 BR PI1009860A8 BR PI1009860 A BRPI1009860 A BR PI1009860A BR PI1009860 A BRPI1009860 A BR PI1009860A BR PI1009860 A8 BRPI1009860 A8 BR PI1009860A8
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- Prior art keywords
- diseases
- prevention
- compound
- humans
- animals
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
uso de um composto e composição farmacêutica ou nutracêutica uso de derivados poli-insaturados de ácido graxo como medicamentos ou alimentos funcionais. a presente invenção refere-se ao uso de derivados de ácido graxo 1,2 para o tratamento ou a prevenção de doenças comuns cuja etiologia seja baseada em alterações (de qualquer tipo) nos lipídios da membrana celular, por exemplo, alterações nos níveis, na composição ou na estrutura desses lipídios. além disso, para doenças nas quais a regulação da composição do lipídio e da estrutura das membranas (ou das proteínas que interagem com as membranas) cause a reversão do estado patológico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200900725A ES2345241B1 (es) | 2009-03-16 | 2009-03-16 | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
| PCT/ES2010/070153 WO2010106211A1 (es) | 2009-03-16 | 2010-03-15 | Uso de derivados de ácidos grasos poliinsaturados como medicamentos |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI1009860A2 BRPI1009860A2 (pt) | 2016-03-08 |
| BRPI1009860A8 true BRPI1009860A8 (pt) | 2019-12-17 |
Family
ID=42673244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1009860A BRPI1009860A8 (pt) | 2009-03-16 | 2010-03-15 | composto, uso do mesmo, composição farmacêutica e método para tratamento terapêutico ou prevenção de doenças em humanos ou animais |
Country Status (18)
| Country | Link |
|---|---|
| US (7) | US9161928B2 (pt) |
| EP (2) | EP2409963B1 (pt) |
| JP (1) | JP5904592B2 (pt) |
| KR (4) | KR102233102B1 (pt) |
| CN (4) | CN106349058B (pt) |
| AU (6) | AU2010224749B2 (pt) |
| BR (1) | BRPI1009860A8 (pt) |
| CA (1) | CA2754963C (pt) |
| CL (1) | CL2011002268A1 (pt) |
| DK (2) | DK2409963T3 (pt) |
| ES (3) | ES2345241B1 (pt) |
| HU (2) | HUE051850T2 (pt) |
| MX (1) | MX2011009614A (pt) |
| PL (1) | PL2409963T3 (pt) |
| PT (2) | PT3159329T (pt) |
| RU (1) | RU2513995C2 (pt) |
| SI (1) | SI3159329T1 (pt) |
| WO (1) | WO2010106211A1 (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2345241B1 (es) * | 2009-03-16 | 2011-09-08 | Lipopharma Therapeutics | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
| US10052299B2 (en) | 2009-10-30 | 2018-08-21 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
| JP6145087B2 (ja) | 2011-04-26 | 2017-06-07 | レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． | Ｐｕｆａ酸化関与障害 |
| KR102112087B1 (ko) | 2011-04-26 | 2020-05-18 | 레트로토프 인코포레이티드 | 에너지 프로세싱 손상 장애 및 미토콘드리아 결함 |
| WO2012148930A2 (en) | 2011-04-26 | 2012-11-01 | Retrotope, Inc. | Oxidative retinal diseases |
| JP6106157B2 (ja) | 2011-04-26 | 2017-03-29 | レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． | 神経変性障害および筋疾患に関与するｐｕｆａ |
| ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
| JP6348229B2 (ja) * | 2014-10-21 | 2018-06-27 | ユニバーシタット デ レス イレス バレアレス | ヒドロキシ−トリグリセリドの合成方法、および疾患の予防および処置のためのその使用 |
| EP3267200A4 (en) * | 2015-03-06 | 2018-08-22 | Niigata University | Biomarker of dementia with lewy bodies |
| EP3950649A1 (en) | 2015-11-23 | 2022-02-09 | Retrotope, Inc. | Site-specific isotopic labeling of 1, 4-diene systems |
| GB201521085D0 (en) * | 2015-11-30 | 2016-01-13 | Biozep As | Use |
| MX2019013683A (es) | 2017-05-16 | 2020-01-15 | Ability Pharmaceuticals Sl | Una combinacion farmaceutica para el tratamiento de un cancer. |
| US10596165B2 (en) | 2018-02-12 | 2020-03-24 | resTORbio, Inc. | Combination therapies |
| WO2019241789A1 (en) | 2018-06-15 | 2019-12-19 | Navitor Pharmaceuticals, Inc. | Rapamycin analogs and uses thereof |
| AU2020397938A1 (en) | 2019-12-05 | 2022-06-23 | Janssen Pharmaceutica Nv | Rapamycin analogs and uses thereof |
| WO2021152201A2 (es) * | 2020-01-29 | 2021-08-05 | Universitat De Les Illes Balears | Metabolitos de ácidos grasos alfa-hidroxilados, usos médicos de los mismos y uso como biomarcadores |
| ES2846824B2 (es) * | 2020-01-29 | 2022-01-19 | Univ Illes Balears | Profarmacos de acidos grasos poliinsaturados y usos medicos de los mismos |
| IL295067A (en) | 2020-02-10 | 2022-09-01 | Ability Pharmaceuticals S L | Pharmaceutical combination for cancer treatment |
| IL295783B2 (en) | 2020-02-21 | 2026-03-01 | Retrotope Inc | Processes for isotopic alteration of polyunsaturated fatty acids and their derivatives |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8717816D0 (en) | 1987-07-28 | 1987-09-03 | Manchester Inst Science Tech | Fabric testing apparatus |
| GB2218984B (en) * | 1988-05-27 | 1992-09-23 | Renafield Limited | Process for preparing high-concentration mixtures of polyunsaturated fatty acids & their esters and their prophylactic or therapeutic uses |
| JPH05974A (ja) * | 1991-06-21 | 1993-01-08 | Sagami Chem Res Center | ハロゲン化不飽和アルキル化合物及びその前駆体 |
| ES2161146B1 (es) * | 1999-06-29 | 2002-07-01 | Consejo Superior Investigacion | Compuestos antimicrobianos, uso y metodo para inducir resistencia a infecciones de bacterias en plantas. |
| US6344574B1 (en) * | 2000-07-20 | 2002-02-05 | The United States Of America As Represented By The Secretary Of Agriculture | Solvent fractionation of chicken fat for making lipid compositions enriched in unsaturated fatty acid-containing triacylglycerols |
| DE10106660A1 (de) * | 2001-02-12 | 2002-08-29 | Celanese Ventures Gmbh | Verfahren zur Herstellung von gamma-Linolensäure aus einer Ciliaten-Kultur durch Zusatz geeigneter Vorläufermoleküle zu dem Kulturmedium |
| ES2186576B1 (es) * | 2001-10-11 | 2004-09-16 | Universitat De Les Illes Balears | Acido 2-hidroxioleico para utilizar como medicamento. |
| AU2003260687A1 (en) * | 2002-04-01 | 2003-10-20 | University Of Southern California | Trihydroxy polyunsaturated eicosanoids |
| US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
| BRPI0516803A (pt) * | 2004-11-19 | 2008-09-23 | Martek Biosciences Corp | oxilipinas de ácidos graxos polinsaturados de cadeia longa e métodos de produção e uso dos mesmos |
| GB0428384D0 (en) * | 2004-12-24 | 2005-02-02 | Sla Pharma Ag | Eicosapentaenoic acid |
| US8324276B2 (en) | 2005-01-24 | 2012-12-04 | Pronova Biopharma Norge As | Fatty acid composition for treatment of alzheimer's disease and cognitive dysfunction |
| WO2006117668A1 (en) * | 2005-05-04 | 2006-11-09 | Pronova Biopharma Norge As | Fatty acid analogues, i.e. dha derivatives for uses as a medicament |
| CN101213281B (zh) * | 2005-05-04 | 2013-03-13 | 普罗诺瓦生物医药挪威公司 | 新的dha衍生物及其作为药物的用途 |
| US8059805B2 (en) * | 2005-06-30 | 2011-11-15 | Emc Corporation | Enhanced services provided using communication redirection and processing |
| BRPI0613358A8 (pt) * | 2005-07-08 | 2017-12-26 | Dsm Ip Assets Bv | ácidos de gordura poli - insaturada para o tratamento da demência e condições relacionadas à pré-demência |
| EP1772146A1 (en) | 2005-10-03 | 2007-04-11 | Neuropharma, S.A. | Polyunsaturated fatty acids as bace inhibitors |
| WO2007058523A1 (en) * | 2005-11-17 | 2007-05-24 | N.V. Nutricia | Composition with docosapentaenoic acid |
| EP1800675B1 (en) * | 2005-12-23 | 2011-05-18 | N.V. Nutricia | Composition comprising polyunsaturated fatty acids, proteins, manganese and/or molybden and nucleosides/nucleotides for treating dementia |
| KR101438177B1 (ko) * | 2006-11-01 | 2014-09-05 | 프로노바 바이오파마 너지 에이에스 | 페록시솜 증식자-활성화 수용체의 활성자 또는 조절자인 알파-치환된 오메가-3 지질 |
| US20110166228A1 (en) | 2006-11-01 | 2011-07-07 | Anne Kristin Holmeide | Composition |
| WO2008053340A1 (en) * | 2006-11-03 | 2008-05-08 | Pronova Biopharma Norge As | A combination product comprising at least one lipid substituted in the alpha position and at least one hypoglycemic agent |
| US20080234377A1 (en) * | 2007-03-23 | 2008-09-25 | Martek Biosciences Corporation | Polyunsaturated fatty acids for treatment of dementia and pre-dementia-related conditions |
| ES2345241B1 (es) | 2009-03-16 | 2011-09-08 | Lipopharma Therapeutics | Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos. |
| ES2401629B1 (es) * | 2011-10-07 | 2014-03-04 | Universitat De Les Illes Balears | Enantiómeros de 2-hidroxiderivados de ácidos grasos y su uso como medicamentos. |
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2009
- 2009-03-16 ES ES200900725A patent/ES2345241B1/es active Active
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2010
- 2010-03-15 RU RU2011141850/04A patent/RU2513995C2/ru active
- 2010-03-15 HU HUE16201132A patent/HUE051850T2/hu unknown
- 2010-03-15 PT PT162011324T patent/PT3159329T/pt unknown
- 2010-03-15 DK DK10753158.4T patent/DK2409963T3/en active
- 2010-03-15 WO PCT/ES2010/070153 patent/WO2010106211A1/es not_active Ceased
- 2010-03-15 AU AU2010224749A patent/AU2010224749B2/en not_active Revoked
- 2010-03-15 HU HUE10753158A patent/HUE032027T2/en unknown
- 2010-03-15 PL PL10753158T patent/PL2409963T3/pl unknown
- 2010-03-15 EP EP10753158.4A patent/EP2409963B1/en active Active
- 2010-03-15 CN CN201610773061.0A patent/CN106349058B/zh active Active
- 2010-03-15 CN CN2010800119398A patent/CN102356057A/zh active Pending
- 2010-03-15 KR KR1020207005917A patent/KR102233102B1/ko active Active
- 2010-03-15 DK DK16201132.4T patent/DK3159329T3/da active
- 2010-03-15 EP EP16201132.4A patent/EP3159329B1/en active Active
- 2010-03-15 KR KR1020187005245A patent/KR20180021931A/ko not_active Ceased
- 2010-03-15 SI SI201032041T patent/SI3159329T1/sl unknown
- 2010-03-15 MX MX2011009614A patent/MX2011009614A/es active IP Right Grant
- 2010-03-15 ES ES16201132T patent/ES2820025T3/es active Active
- 2010-03-15 CA CA2754963A patent/CA2754963C/en active Active
- 2010-03-15 KR KR1020117024210A patent/KR101833772B1/ko active Active
- 2010-03-15 BR BRPI1009860A patent/BRPI1009860A8/pt active Search and Examination
- 2010-03-15 ES ES10753158.4T patent/ES2613606T3/es active Active
- 2010-03-15 CN CN201910095352.2A patent/CN109999018A/zh active Pending
- 2010-03-15 PT PT107531584T patent/PT2409963T/pt unknown
- 2010-03-15 CN CN201610773030.5A patent/CN106420686B/zh active Active
- 2010-03-15 KR KR1020197004239A patent/KR20190018754A/ko not_active Ceased
- 2010-03-15 US US13/257,128 patent/US9161928B2/en active Active
- 2010-03-15 JP JP2012500281A patent/JP5904592B2/ja active Active
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2011
- 2011-09-13 CL CL2011002268A patent/CL2011002268A1/es unknown
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2015
- 2015-09-29 US US14/869,045 patent/US9763906B2/en active Active
- 2015-09-29 US US14/869,080 patent/US9763907B2/en active Active
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2016
- 2016-07-13 US US15/209,540 patent/US9907772B2/en active Active
- 2016-10-07 AU AU2016238970A patent/AU2016238970B2/en not_active Revoked
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2017
- 2017-08-22 US US15/683,379 patent/US10201515B2/en active Active
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2018
- 2018-06-05 AU AU2018203976A patent/AU2018203976B2/en not_active Expired - Fee Related
- 2018-12-18 US US16/224,262 patent/US20190365690A1/en not_active Abandoned
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2019
- 2019-09-06 AU AU2019226257A patent/AU2019226257B2/en active Active
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2020
- 2020-04-22 US US16/855,463 patent/US11253497B2/en active Active
- 2020-07-13 AU AU2020205214A patent/AU2020205214B2/en active Active
- 2020-07-13 AU AU2020205213A patent/AU2020205213B2/en active Active
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| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] |