BRPI1010256A2 - "aplicações terapêuticas no domínio cardiovascular de derivados de quinazolina diona." - Google Patents

"aplicações terapêuticas no domínio cardiovascular de derivados de quinazolina diona."

Info

Publication number
BRPI1010256A2
BRPI1010256A2 BRPI1010256A BRPI1010256A BRPI1010256A2 BR PI1010256 A2 BRPI1010256 A2 BR PI1010256A2 BR PI1010256 A BRPI1010256 A BR PI1010256A BR PI1010256 A BRPI1010256 A BR PI1010256A BR PI1010256 A2 BRPI1010256 A2 BR PI1010256A2
Authority
BR
Brazil
Prior art keywords
therapeutic applications
dione derivatives
cardiovascular field
quinazoline dione
quinazoline
Prior art date
Application number
BRPI1010256A
Other languages
English (en)
Inventor
Fabrice Viviani
Gilbert Marciniak
Jean-François Nave
Philip Janiak
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of BRPI1010256A2 publication Critical patent/BRPI1010256A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI1010256A 2009-04-09 2010-04-07 "aplicações terapêuticas no domínio cardiovascular de derivados de quinazolina diona." BRPI1010256A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0901755A FR2944206B1 (fr) 2009-04-09 2009-04-09 Applications therapeutiques dans le domaine cardiovasculaire de derives de quinazolinedione
PCT/FR2010/050672 WO2010116090A1 (fr) 2009-04-09 2010-04-07 Applications thérapeutiques dans le domaine cardiovasculaire de dérivés de quinazolinedione

Publications (1)

Publication Number Publication Date
BRPI1010256A2 true BRPI1010256A2 (pt) 2016-03-22

Family

ID=41181038

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1010256A BRPI1010256A2 (pt) 2009-04-09 2010-04-07 "aplicações terapêuticas no domínio cardiovascular de derivados de quinazolina diona."

Country Status (34)

Country Link
US (1) US8846654B2 (pt)
EP (1) EP2416777B1 (pt)
JP (1) JP5685578B2 (pt)
KR (1) KR101686267B1 (pt)
CN (1) CN102458409B (pt)
AR (1) AR076232A1 (pt)
AU (1) AU2010233596B2 (pt)
BR (1) BRPI1010256A2 (pt)
CA (1) CA2758234A1 (pt)
CL (1) CL2011002525A1 (pt)
CO (1) CO6440577A2 (pt)
CR (1) CR20110527A (pt)
CY (1) CY1115987T1 (pt)
DK (1) DK2416777T3 (pt)
DO (1) DOP2011000306A (pt)
EA (1) EA020984B1 (pt)
EC (1) ECSP11011377A (pt)
ES (1) ES2528633T3 (pt)
FR (1) FR2944206B1 (pt)
HR (1) HRP20150106T1 (pt)
HU (1) HUE024161T2 (pt)
IL (1) IL215610A (pt)
MA (1) MA33254B1 (pt)
MX (1) MX2011010645A (pt)
NI (1) NI201100180A (pt)
NZ (1) NZ595660A (pt)
PL (1) PL2416777T3 (pt)
PT (1) PT2416777E (pt)
SG (2) SG175131A1 (pt)
SI (1) SI2416777T1 (pt)
TN (1) TN2011000506A1 (pt)
TW (1) TWI457330B (pt)
UY (1) UY32555A (pt)
WO (1) WO2010116090A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2944282B1 (fr) * 2009-04-09 2013-05-03 Sanofi Aventis Derives de quinazolinedione, leur preparation et leurs diverses applications therapeutiques
EP2854780B1 (en) 2012-06-05 2017-08-30 University Of Kansas Inhibitors of respiratory syncytial virus
US9951038B2 (en) 2012-12-27 2018-04-24 Purdue Pharma L.P. Quinazolin-4(3H)-one-type piperidine compounds and uses thereof
EP4304586A4 (en) 2021-03-10 2025-04-02 Jnana Therapeutics Inc. SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION
US20260048059A1 (en) 2022-08-18 2026-02-19 Klaus Wirth Use of substituted benzoxazole and benzofuran compounds for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exertional intoleranc
KR20260022325A (ko) * 2023-06-14 2026-02-19 제이나나 테라퓨틱스 인코포레이티드 Slc6a19 기능의 피페리딘 억제제
US12258345B1 (en) 2023-12-12 2025-03-25 King Faisal University Pyrrolo[3,2-c]isoquinoline-2,3-dione compounds as CK2 inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3879393A (en) * 1973-06-18 1975-04-22 Miles Lab Derivatives of 1,3-disubstituted 2,4(1h,3h)-quinazolinediones
JPS56164172A (en) * 1980-05-22 1981-12-17 Masayuki Ishikawa Novel 2,4 1h,3h -quinazolinedione derivative
EP0040793B1 (en) * 1980-05-22 1985-08-28 Masayuki Ishikawa Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof
US5624926A (en) 1993-02-18 1997-04-29 Kyowa Hakko Kogyo Co., Ltd. Piperidinyl-dioxoquinazolines as adenosine reuptake inhibitors
DE69906059D1 (de) 1998-04-20 2003-04-24 Fujisawa Pharmaceutical Co Anthranilsäurederivate als inhibitoren der c-gmp-phosphodiesterase
WO2001044228A2 (fr) 1999-12-14 2001-06-21 Sanofi-Synthelabo Derives de quinazolinedione et phtalimide, leurs preparations et leurs applications en therapeutique
CA2599662A1 (en) 2005-03-01 2006-09-08 Pfizer Limited Use of pde7 inhibitors for the treatment of neuropathic pain
WO2006092692A1 (en) 2005-03-01 2006-09-08 Pfizer Limited Use of combinations of pde7 inhibitors and alpha-2-delty ligands for the treatment of neuropathic pain
WO2007067946A2 (en) 2005-12-07 2007-06-14 The Regents Of The University Of California Diagnosis and treatment of chronic lymphocytic leukemia (cll)
JP5580192B2 (ja) 2007-03-27 2014-08-27 オメロス コーポレーション 運動障害の処置のためのｐｄｅ７インヒビターの使用
US20100113391A1 (en) 2007-04-19 2010-05-06 Astellas Pharma Inc. Bicyclic heterocyclic compound
FR2921926B1 (fr) * 2007-10-03 2009-12-04 Sanofi Aventis Derives de quinazolinedione,leur preparation et leurs applications therapeutiques.
FR2943673B1 (fr) * 2009-03-27 2013-03-29 Sanofi Aventis Applications therapeutiques de derives de quinazolinedione

Also Published As

Publication number Publication date
WO2010116090A1 (fr) 2010-10-14
AR076232A1 (es) 2011-05-26
CR20110527A (es) 2014-05-12
DOP2011000306A (es) 2011-10-31
AU2010233596A1 (en) 2011-11-03
CL2011002525A1 (es) 2012-02-17
ECSP11011377A (es) 2011-11-30
CN102458409A (zh) 2012-05-16
EA020984B1 (ru) 2015-03-31
PT2416777E (pt) 2015-02-04
PL2416777T3 (pl) 2015-05-29
UY32555A (es) 2010-11-30
US20120184522A1 (en) 2012-07-19
EA201171229A1 (ru) 2012-12-28
NI201100180A (es) 2012-01-11
HK1165997A1 (en) 2012-10-19
EP2416777B1 (fr) 2014-11-12
SI2416777T1 (sl) 2015-02-27
KR101686267B1 (ko) 2016-12-13
IL215610A (en) 2013-07-31
TWI457330B (zh) 2014-10-21
TN2011000506A1 (fr) 2013-05-24
HUE024161T2 (hu) 2016-02-29
MX2011010645A (es) 2012-01-19
CO6440577A2 (es) 2012-05-15
US8846654B2 (en) 2014-09-30
MA33254B1 (fr) 2012-05-02
IL215610A0 (en) 2011-12-29
ES2528633T3 (es) 2015-02-11
FR2944206B1 (fr) 2012-12-28
JP2012523398A (ja) 2012-10-04
JP5685578B2 (ja) 2015-03-18
SG10201400420PA (en) 2014-05-29
SG175131A1 (en) 2011-11-28
KR20120005499A (ko) 2012-01-16
HRP20150106T1 (hr) 2015-05-08
EP2416777A1 (fr) 2012-02-15
CY1115987T1 (el) 2017-01-25
TW201040155A (en) 2010-11-16
FR2944206A1 (fr) 2010-10-15
DK2416777T3 (en) 2015-02-09
CN102458409B (zh) 2014-06-18
AU2010233596B2 (en) 2016-06-23
NZ595660A (en) 2013-03-28
CA2758234A1 (fr) 2010-10-14

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]