BRPI1010957A2 - variantes de celulase com expressão, atividade e/ou estabilidade aprimorada e uso das mesmas. - Google Patents
variantes de celulase com expressão, atividade e/ou estabilidade aprimorada e uso das mesmas.Info
- Publication number
- BRPI1010957A2 BRPI1010957A2 BRPI1010957A BRPI1010957A BRPI1010957A2 BR PI1010957 A2 BRPI1010957 A2 BR PI1010957A2 BR PI1010957 A BRPI1010957 A BR PI1010957A BR PI1010957 A BRPI1010957 A BR PI1010957A BR PI1010957 A2 BRPI1010957 A2 BR PI1010957A2
- Authority
- BR
- Brazil
- Prior art keywords
- activity
- stability
- improved expression
- cellulase variants
- cellulase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01091—Cellulose 1,4-beta-cellobiosidase (3.2.1.91)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18395909P | 2009-06-03 | 2009-06-03 | |
| PCT/US2010/037328 WO2010141779A1 (en) | 2009-06-03 | 2010-06-03 | Cellulase variants with improved expression, activity and/or stability, and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1010957A2 true BRPI1010957A2 (pt) | 2018-02-06 |
Family
ID=42493879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1010957A BRPI1010957A2 (pt) | 2009-06-03 | 2010-06-03 | variantes de celulase com expressão, atividade e/ou estabilidade aprimorada e uso das mesmas. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8679816B2 (pt) |
| EP (1) | EP2438164B1 (pt) |
| JP (1) | JP2012528598A (pt) |
| KR (1) | KR20120062643A (pt) |
| CN (2) | CN102803482B (pt) |
| AU (1) | AU2010256519B2 (pt) |
| BR (1) | BRPI1010957A2 (pt) |
| CA (1) | CA2764094A1 (pt) |
| CO (1) | CO6470854A2 (pt) |
| MX (1) | MX2011012841A (pt) |
| RU (1) | RU2011154243A (pt) |
| WO (1) | WO2010141779A1 (pt) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2010013099A (es) | 2008-06-06 | 2010-12-21 | Danisco Inc | Composiciones y metodos que comprenden variantes de celulasa con afinidad reducida a materiales no celulosicos. |
| BRPI0916767A2 (pt) * | 2008-07-16 | 2018-10-16 | Iogen Energy Corp | glicosidades bda família 6 modificadas com especificidade de substrato alterada |
| CA2755029A1 (en) * | 2009-04-06 | 2010-10-14 | California Institute Of Technology | Polypeptides having cellulase activity |
| JP5932648B2 (ja) | 2009-09-23 | 2016-06-15 | ダニスコ・ユーエス・インク | 新規なグリコシルヒドロラーゼ酵素及びその用途 |
| PH12012500999A1 (en) | 2009-12-23 | 2013-02-11 | Danisco Us Inc | Methods for improving the efficiency of simultaneous saccharification and fermentation reactions |
| WO2011097713A1 (en) * | 2010-02-11 | 2011-08-18 | Iogen Energy Corporation | Carbohydrate binding modules with reduced binding to lignin |
| BR112012020503A2 (pt) | 2010-03-31 | 2015-09-15 | Novozymes Inc | variante isolado de celobioidrolase precursor, polipeptídeo isolado, construção de ácido nucleico, vetor de expressão, célula hospedeira, método de produzir um variante de celobioidrolas precursor, métodos para obter o variante, para degradar variante de celobioidrolase precursor, métodos para obter o variante, para degradar ou converter um material celulósico, poara produzir um produto de fermentação e de fermentar um material celulósico, e, composição de enzima. |
| US8759064B2 (en) | 2010-05-14 | 2014-06-24 | Codexis, Inc. | Cellobiohydrolase variants |
| CA2801799C (en) | 2010-06-03 | 2018-11-20 | Danisco Us Inc. | Filamentous fungal host strains and dna constructs, and methods of use thereof |
| EP2613647B1 (en) | 2010-09-06 | 2018-02-14 | DuPont Nutrition Biosciences ApS | Food additive comprising an amidase for detoxifying ochratoxin. |
| US9080161B2 (en) | 2011-01-26 | 2015-07-14 | Novozymes, Inc. | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| MX2013010512A (es) | 2011-03-17 | 2013-10-07 | Danisco Inc | Metodo para reducir la viscosidad en un proceso de sacarificacion. |
| WO2012129697A1 (en) * | 2011-04-01 | 2012-10-04 | Adrian Tsang | Novel cell wall deconstruction enzymes of talaromyces thermophilus and uses thereof |
| US20120276594A1 (en) * | 2011-04-27 | 2012-11-01 | Codexis, Inc. | Cellobiohydrolase variants |
| JP2012235767A (ja) * | 2011-04-27 | 2012-12-06 | Toyota Motor Corp | 変異トリコデルマ属微生物及びこれを用いたタンパク質の製造方法 |
| WO2013028278A1 (en) | 2011-08-23 | 2013-02-28 | Codexis, Inc. | Cellobiohydrolase variants |
| JP2015500041A (ja) | 2011-12-13 | 2015-01-05 | ダニスコ・ユーエス・インク | 混合培養物から調製された酵素カクテル |
| US10036050B2 (en) * | 2011-12-20 | 2018-07-31 | Novozymes, Inc. | Cellobiohydrolase variants and polynucleotides encoding same |
| CA2857755A1 (en) | 2011-12-21 | 2013-06-27 | Danisco Us Inc. | Improving fungal gene expression using insulator dna sequences |
| US9677058B2 (en) | 2011-12-22 | 2017-06-13 | Dupont Nutrition Biosciences Aps | Polypeptides having glucoamylase activity and method of producing the same |
| MX2015002099A (es) | 2012-08-22 | 2015-05-11 | Dupont Nutrition Biosci Aps | Variantes que tienen actividad glucoamilasa. |
| CA2888757A1 (en) | 2012-10-31 | 2014-05-08 | Danisco Us Inc. | Compositions and methods of use |
| EP2914717A1 (en) | 2012-10-31 | 2015-09-09 | Danisco US Inc. | Beta-glucosidase from magnaporthe grisea |
| MX2015005424A (es) | 2012-10-31 | 2015-08-05 | Danisco Inc | Beta-glucosidasa de neurospora crassa. |
| WO2014078546A2 (en) * | 2012-11-15 | 2014-05-22 | Bp Corporation North America Inc. | Variant cbh ii polypeptides with improved specific activity |
| BR112015012968A2 (pt) | 2012-12-07 | 2017-09-12 | Danisco Us Inc | composições e métodos de uso |
| DK2929022T3 (en) | 2012-12-07 | 2017-02-13 | Danisco Us Inc | COMPOSITIONS AND METHODS OF USE |
| CA2892624A1 (en) | 2012-12-12 | 2014-06-19 | Danisco Us Inc. | Variants of cellobiohydrolases |
| CA2890849A1 (en) | 2012-12-12 | 2014-06-19 | Danisco Us Inc. | Variants of cellobiohydrolases |
| MX2015007234A (es) | 2012-12-12 | 2015-10-29 | Danisco Us Inc | Variantes de celobiohidrolasas. |
| WO2014093294A1 (en) | 2012-12-12 | 2014-06-19 | Danisco Us Inc. | Variants of cellobiohydrolases |
| KR20150095726A (ko) | 2012-12-12 | 2015-08-21 | 다니스코 유에스 인크. | 셀로바이오하이드롤라제의 변이체 |
| US8778641B1 (en) * | 2013-02-12 | 2014-07-15 | Novozymes Inc. | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| US8778640B1 (en) * | 2013-02-12 | 2014-07-15 | Novozymes Inc. | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| CN110628749A (zh) * | 2013-03-08 | 2019-12-31 | 诺维信公司 | 纤维二糖水解酶变体和编码它们的多核苷酸 |
| US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
| CN105916981A (zh) | 2013-07-29 | 2016-08-31 | 丹尼斯科美国公司 | 变体酶 |
| CN105829530A (zh) | 2013-12-04 | 2016-08-03 | 丹尼斯科美国公司 | 包含β-葡萄糖苷酶多肽的组合物及其使用方法 |
| US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
| EP3201330A1 (en) | 2014-09-30 | 2017-08-09 | Danisco US Inc. | Compositions comprising beta mannanase and methods of use |
| EP3201332A1 (en) | 2014-09-30 | 2017-08-09 | Danisco US Inc. | Compositions comprising beta-mannanase and methods of use |
| WO2016054185A1 (en) | 2014-09-30 | 2016-04-07 | Danisco Us Inc | Compositions comprising beta-mannanase and methods of use |
| WO2016054168A1 (en) | 2014-09-30 | 2016-04-07 | Danisco Us Inc | Compositions comprising beta mannanase and methods of use |
| EP3201334A1 (en) | 2014-09-30 | 2017-08-09 | Danisco US Inc. | Compositions comprising beta-mannanase and methods of use |
| BR112017008595A2 (pt) | 2014-10-27 | 2017-12-19 | Danisco Us Inc | composições e métodos referentes à beta-glucosidase |
| US20180148683A1 (en) | 2015-07-07 | 2018-05-31 | Danisco Us Inc. | Induction of gene expression using a high concentration sugar mixture |
| KR20180117166A (ko) | 2016-03-04 | 2018-10-26 | 다니스코 유에스 인크. | 미생물에서의 단백질 생산을 위한 유전자 조작 리보솜 프로모터 |
| WO2018053058A1 (en) | 2016-09-14 | 2018-03-22 | Danisco Us Inc. | Lignocellulosic biomass fermentation-based processes |
| KR102593668B1 (ko) | 2016-10-04 | 2023-10-24 | 다니스코 유에스 인크. | 유도 기질 부재 하의 사상 진균 세포에서의 단백질 생산 |
| WO2018106656A1 (en) | 2016-12-06 | 2018-06-14 | Danisco Us Inc | Truncated lpmo enzymes and use thereof |
| CN110291195B (zh) * | 2016-12-15 | 2024-10-15 | 丹尼斯科美国公司 | 具有内切葡聚糖酶活性的多肽及其用途 |
| EP4644560A3 (en) | 2016-12-21 | 2026-04-08 | International N&H Denmark ApS | Methods of using thermostable serine proteases |
| WO2019074828A1 (en) | 2017-10-09 | 2019-04-18 | Danisco Us Inc | CELLOBIOSE DEHYDROGENASE VARIANTS AND METHODS OF USE |
| EP3703661A1 (en) | 2017-11-02 | 2020-09-09 | Danisco US Inc. | Freezing point depressed solid matrix compositions for melt granulation of enzymes |
| CN109897840B (zh) * | 2017-12-08 | 2021-10-22 | 中国科学院天津工业生物技术研究所 | 聚磷酸依赖型葡萄糖激酶变体及其应用 |
| EP3530743A1 (en) | 2018-02-21 | 2019-08-28 | Cambridge Glycoscience Ltd | Method of production |
| MX2021000113A (es) * | 2018-07-10 | 2021-03-09 | Novozymes As | Metodo de fabricacion de papel o carton. |
| JP7374991B2 (ja) | 2018-08-15 | 2023-11-07 | ケンブリッジ グリコサイエンス エルティーディー | 新規組成物、それらの使用、およびそれらの形成方法 |
| WO2021032647A1 (en) | 2019-08-16 | 2021-02-25 | Cambridge Glycoscience Ltd | Methods of treating biomass to produce oligosaccharides and related compositions |
| WO2021116437A2 (en) | 2019-12-12 | 2021-06-17 | Cambridge Glycoscience Ltd | Low sugar multiphase foodstuffs |
| CN116334020B (zh) * | 2023-02-28 | 2025-11-11 | 南京工业大学 | 一种6'-唾液酸转移酶突变体及其应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US245269A (en) | 1881-08-09 | Machine for rasping pegs | ||
| GB1368599A (en) | 1970-09-29 | 1974-10-02 | Unilever Ltd | Softening compositions |
| GB1358599A (en) | 1970-12-22 | 1974-07-03 | Monacelli Umberto | Gun for firing tacks |
| DK187280A (da) | 1980-04-30 | 1981-10-31 | Novo Industri As | Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode |
| GB2094826B (en) | 1981-03-05 | 1985-06-12 | Kao Corp | Cellulase enzyme detergent composition |
| GB2095275B (en) | 1981-03-05 | 1985-08-07 | Kao Corp | Enzyme detergent composition |
| US4822516A (en) | 1986-12-08 | 1989-04-18 | Kao Corporation | Detergent composition for clothing incorporating a cellulase |
| JP2728531B2 (ja) | 1988-03-24 | 1998-03-18 | ノボ ノルディスク アクティーゼルスカブ | セルラーゼ調製品 |
| US5648263A (en) | 1988-03-24 | 1997-07-15 | Novo Nordisk A/S | Methods for reducing the harshness of a cotton-containing fabric |
| DK494089D0 (pt) | 1989-10-06 | 1989-10-06 | Novo Nordisk As | |
| US5650322A (en) | 1990-10-05 | 1997-07-22 | Genencor International, Inc. | Methods for stonewashing fabrics using endoglucanases |
| CA2093422C (en) | 1990-10-05 | 2001-04-03 | Genencor International, Inc. | DETERGENT COMPOSITIONS CONTAINING LOW CBH I CONTENT CELLULASE COMPOSITIONS |
| US5246853A (en) | 1990-10-05 | 1993-09-21 | Genencor International, Inc. | Method for treating cotton-containing fabric with a cellulase composition containing endoglucanase components and which composition is free of exo-cellobiohydrolase I |
| CA2093424C (en) | 1990-10-05 | 2000-05-02 | Kathleen A. Clarkson | Methods for treating cotton-containing fabrics with cellulase |
| US5475101A (en) | 1990-10-05 | 1995-12-12 | Genencor International, Inc. | DNA sequence encoding endoglucanase III cellulase |
| FI932521A0 (fi) | 1993-06-02 | 1993-06-02 | Alko Ab Oy | Nytt endoglukanasenzym |
| US5861271A (en) | 1993-12-17 | 1999-01-19 | Fowler; Timothy | Cellulase enzymes and systems for their expressions |
| BR9712761B1 (pt) | 1996-11-13 | 2010-02-23 | mÉtodo para a produÇço de 1,3- propanodiol e microorganismo hospedeiro transformado. | |
| US6265204B1 (en) | 1997-01-17 | 2001-07-24 | Genencor International, Inc. | DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi |
| JP4307563B2 (ja) | 1997-04-07 | 2009-08-05 | ユニリーバー・ナームローゼ・ベンノートシャープ | 糸状菌、特にアスペルギルス属に属する糸状菌のアグロバクテリウム媒介性形質転換 |
| US6599722B2 (en) | 1998-12-22 | 2003-07-29 | Genencor International, Inc. | Method for producing ascorbic acid intermediates |
| DK1862539T3 (da) | 2003-05-29 | 2012-05-14 | Danisco Us Inc | Nye trichodermagener |
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| CN101094917B (zh) | 2004-12-30 | 2012-04-25 | 金克克国际有限公司 | 新型变体红褐肉座菌cbh2纤维素酶 |
| JP4991700B2 (ja) | 2005-04-12 | 2012-08-01 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | バイオマス処理のためのシステムおよび方法 |
| US7785854B2 (en) * | 2006-08-31 | 2010-08-31 | Iogen Energy Corporation | Modified cellulases with increased thermostability, thermophilicity, and alkalophilicity |
| EP2069512B1 (en) | 2006-09-22 | 2010-06-16 | Danisco US, INC., Genencor Division | Acetolactate synthase from trichoderma reesei as selectable marker |
| BRPI0812448A2 (pt) * | 2007-06-06 | 2014-10-14 | Danisco Us Inc Genecor Division | Método para aperfeiçoamento de propriedades de proteína |
| PL2481796T3 (pl) | 2007-10-09 | 2014-11-28 | Danisco Us Inc | Odmiany glukoamylazy |
| MX2010013099A (es) * | 2008-06-06 | 2010-12-21 | Danisco Inc | Composiciones y metodos que comprenden variantes de celulasa con afinidad reducida a materiales no celulosicos. |
| KR101050460B1 (ko) | 2009-03-25 | 2011-07-20 | 삼성모바일디스플레이주식회사 | 유기 발광 표시 장치 및 그의 제조 방법 |
-
2010
- 2010-06-03 KR KR1020117028397A patent/KR20120062643A/ko not_active Withdrawn
- 2010-06-03 WO PCT/US2010/037328 patent/WO2010141779A1/en not_active Ceased
- 2010-06-03 EP EP10722895.9A patent/EP2438164B1/en not_active Not-in-force
- 2010-06-03 US US13/321,928 patent/US8679816B2/en not_active Expired - Fee Related
- 2010-06-03 CN CN201080024295.6A patent/CN102803482B/zh not_active Expired - Fee Related
- 2010-06-03 AU AU2010256519A patent/AU2010256519B2/en not_active Expired - Fee Related
- 2010-06-03 JP JP2012514152A patent/JP2012528598A/ja active Pending
- 2010-06-03 CA CA2764094A patent/CA2764094A1/en not_active Abandoned
- 2010-06-03 CN CN201510187939.8A patent/CN104862293A/zh active Pending
- 2010-06-03 RU RU2011154243/10A patent/RU2011154243A/ru not_active Application Discontinuation
- 2010-06-03 MX MX2011012841A patent/MX2011012841A/es not_active Application Discontinuation
- 2010-06-03 BR BRPI1010957A patent/BRPI1010957A2/pt not_active Application Discontinuation
-
2011
- 2011-12-01 CO CO11165857A patent/CO6470854A2/es not_active Application Discontinuation
-
2014
- 2014-02-25 US US14/189,943 patent/US9523087B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012528598A (ja) | 2012-11-15 |
| EP2438164A1 (en) | 2012-04-11 |
| US8679816B2 (en) | 2014-03-25 |
| US20140302585A1 (en) | 2014-10-09 |
| MX2011012841A (es) | 2012-01-27 |
| CA2764094A1 (en) | 2010-12-09 |
| US9523087B2 (en) | 2016-12-20 |
| CO6470854A2 (es) | 2012-06-29 |
| CN102803482B (zh) | 2015-04-29 |
| AU2010256519A1 (en) | 2011-11-24 |
| RU2011154243A (ru) | 2013-07-20 |
| CN102803482A (zh) | 2012-11-28 |
| KR20120062643A (ko) | 2012-06-14 |
| US20120135500A1 (en) | 2012-05-31 |
| CN104862293A (zh) | 2015-08-26 |
| AU2010256519B2 (en) | 2016-03-17 |
| WO2010141779A1 (en) | 2010-12-09 |
| EP2438164B1 (en) | 2017-08-02 |
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