BRPI1011822A2 - "compostos de 3-substituída-8-substituída-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-ona e sua aplicação" - Google Patents

"compostos de 3-substituída-8-substituída-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-ona e sua aplicação"

Info

Publication number: BRPI1011822A2
Authority: BR; Brazil
Prior art keywords: substituted; tetrazin; imidazo; compounds; application
Prior art date: 2009-06-23

Application number

BRPI1011822A

Other languages

English (en)

Inventor

David Cousin

Malcolm Francis Graham Stevens

Marc Geoffery Hummersone

Original Assignee

Pharminox Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-06-23

Filing date

2010-06-23

Publication date

2016-03-29

2010-06-23 Application filed by Pharminox Ltd filed Critical Pharminox Ltd

2016-03-29 Publication of BRPI1011822A2 publication Critical patent/BRPI1011822A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

BRPI1011822A 2009-06-23 2010-06-23 "compostos de 3-substituída-8-substituída-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-ona e sua aplicação" BRPI1011822A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US21957509P	2009-06-23	2009-06-23
PCT/GB2010/001233 WO2010149968A1 (en)	2009-06-23	2010-06-23	3-substituted-8-substituted-3h imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use

Publications (1)

Publication Number	Publication Date
BRPI1011822A2 true BRPI1011822A2 (pt)	2016-03-29

Family

ID=42563083

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI1011822A BRPI1011822A2 (pt)	2009-06-23	2010-06-23	"compostos de 3-substituída-8-substituída-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-ona e sua aplicação"

Country Status (12)

Country	Link
US (1)	US9024018B2 (pt)
EP (1)	EP2445915B1 (pt)
JP (1)	JP2012530775A (pt)
CN (1)	CN102803264A (pt)
AU (1)	AU2010264339A1 (pt)
BR (1)	BRPI1011822A2 (pt)
CA (1)	CA2763766A1 (pt)
ES (1)	ES2583006T3 (pt)
IL (1)	IL216794A0 (pt)
PL (1)	PL2445915T3 (pt)
WO (1)	WO2010149968A1 (pt)
ZA (1)	ZA201108849B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PE20091101A1 (es)	2007-12-18	2009-07-26	Pharminox Ltd	AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
CA2763766A1 (en)	2009-06-23	2010-12-29	Pharminox Limited	3-substituted-8-substituted-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
US8937303B2 (en)	2010-10-22	2015-01-20	Commonwealth Scientific And Industrial Research Organisation	Organic electroluminescent device
WO2012085501A1 (en) *	2010-12-20	2012-06-28	Pharminox Limited	8 - sulfo - imidazotetrazin- 4 - one compounds and their use as anticancer drug
US10562901B2 (en) *	2016-09-22	2020-02-18	The University Of Massachusetts	Temozolomide compounds, polymers prepared therefrom, and method of treating a disease
CA3109191A1 (en) *	2018-08-09	2020-02-13	The Board Of Trustees Of The University Of Illinois	Imidazotetrazine compounds
GB201907813D0 (en)	2019-05-31	2019-07-17	Univ Nottingham	Therapeutic compounds
US20240400572A1 (en) *	2021-09-23	2024-12-05	Yale University	Compounds and methods for treating cancers that are mgmt deficient regardless of mmr status

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5260291A (en)	1981-08-24	1993-11-09	Cancer Research Campaign Technology Limited	Tetrazine derivatives
OA07174A (fr)	1981-08-24	1984-04-30	May & Baker Ltd	Nouvelles imidazotétrazionones, leur préparation et les médicaments qui les contiennent.
GB2125402B (en)	1982-08-17	1985-11-13	May & Baker Ltd	New tetrazine derivatives
US4504475A (en)	1983-05-24	1985-03-12	Warner Lambert Company	3-(Haloethyl)-4-oxopyrazolo[5,1-D]-1,2,3,5-tetrazine-8-carboxamide compounds
GB8616125D0 (en) *	1986-07-02	1986-08-06	May & Baker Ltd	Compositions of matter
GB9504361D0 (en)	1995-03-04	1995-04-26	Glaxo Spa	Heterocyclic compounds
WO2002057269A1 (en)	2001-01-18	2002-07-25	Schering Corporation	Synthesis of temozolomide and analogs
CN1742723A (zh) *	2004-09-02	2006-03-08	天津倍方科技发展有限公司	含有替莫唑胺－8－羧酸酯的药物组合物以及该类化合物用于制备抗肿瘤药物的用途
PE20091101A1 (es)	2007-12-18	2009-07-26	Pharminox Ltd	AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
GB0807103D0 (en)	2008-04-18	2008-05-21	Univ Bradford The	Compounds
CA2763766A1 (en)	2009-06-23	2010-12-29	Pharminox Limited	3-substituted-8-substituted-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
EP2542553A1 (en)	2010-03-01	2013-01-09	Pharminox Ltd	Methods and intermediates for the synthesis of 4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazines

2010
- 2010-06-23 CA CA2763766A patent/CA2763766A1/en not_active Abandoned
- 2010-06-23 PL PL10727119.9T patent/PL2445915T3/pl unknown
- 2010-06-23 AU AU2010264339A patent/AU2010264339A1/en not_active Abandoned
- 2010-06-23 CN CN2010800282968A patent/CN102803264A/zh active Pending
- 2010-06-23 JP JP2012516848A patent/JP2012530775A/ja active Pending
- 2010-06-23 WO PCT/GB2010/001233 patent/WO2010149968A1/en not_active Ceased
- 2010-06-23 US US13/376,945 patent/US9024018B2/en active Active
- 2010-06-23 ES ES10727119.9T patent/ES2583006T3/es active Active
- 2010-06-23 BR BRPI1011822A patent/BRPI1011822A2/pt not_active Application Discontinuation
- 2010-06-23 EP EP10727119.9A patent/EP2445915B1/en not_active Not-in-force
2011
- 2011-12-01 ZA ZA2011/08849A patent/ZA201108849B/en unknown
- 2011-12-06 IL IL216794A patent/IL216794A0/en unknown

Also Published As

Publication number	Publication date
US9024018B2 (en)	2015-05-05
ES2583006T3 (es)	2016-09-16
AU2010264339A1 (en)	2011-12-22
JP2012530775A (ja)	2012-12-06
HK1172321A1 (zh)	2013-04-19
PL2445915T3 (pl)	2016-10-31
CA2763766A1 (en)	2010-12-29
CN102803264A (zh)	2012-11-28
ZA201108849B (en)	2013-02-27
US20120083513A1 (en)	2012-04-05
WO2010149968A1 (en)	2010-12-29
IL216794A0 (en)	2012-02-29
EP2445915B1 (en)	2016-04-20
EP2445915A1 (en)	2012-05-02

Legal Events

Date	Code	Title	Description
2016-05-31	B11A	Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
2016-08-16	B11Y	Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]

Publication	Publication Date	Title
BR112012012872A2 (pt)	2017-10-10	"pirrolindinas de espiroindolinona"
BRPI0910229A2 (pt)	2015-09-01	Tetramatos de 4';4'-dioxaspiro espirociclicamente substituídos
BRPI0914155A2 (pt)	2015-10-20	preparações de xampu
EP2316414A4 (en)	2011-09-21	HAIR CARE COMPOSITION
BRPI1010909A2 (pt)	2015-09-08	"inseticida arilpirrolinas"
BRPI0922904A2 (pt)	2018-05-29	"compostos"
BRPI0815277A2 (pt)	2015-02-03	"monitores de particulado"
BR112012016733A2 (pt)	2015-09-01	"composto, composição fungicida e método"
BRPI0815588A2 (pt)	2015-02-18	Compostos de poliorganossiloxano-poliuréia e/ou de poliorganossilo-xano-poliuretano
EP2238539A4 (en)	2012-05-02	AUTOMATED APPLICATION DEPENDENCE IMAGING
BRPI0916123A2 (pt)	2015-11-03	"composição de xampu concentrada"
BR112012000735A2 (pt)	2016-11-16	"métodos, kits e conjuntos de compostos"
EP2393743A4 (en)	2013-03-20	FEEDER SYSTEM
BRPI0914533A2 (pt)	2015-12-15	"métodos"
BRPI0614464A2 (pt)	2016-11-08	preparação cosmética
BRPI1007878A2 (pt)	2015-09-01	"compostos inseticidas"
BRPI0914152A2 (pt)	2015-10-20	preparações de xampu
EP2137636A4 (en)	2010-07-07	APPLICATION INSULATION SYSTEM
BRPI0920850A2 (pt)	2016-09-13	novos compostos e sua utilização
BRPI1013004A2 (pt)	2018-03-20	"elementos de filtro e conjunto de filtro"
BRPI0914503A2 (pt)	2016-01-12	"composição de shampoo concentrado"
BRPI0912810A2 (pt)	2016-05-17	"filtro"
EP2258697A4 (en)	2011-08-03	HYDROXYCHINOXALINCARBOXAMIDDERIVAT
FI20070265L (fi)	2008-10-06	Rosti
BRPI0809817A2 (pt)	2014-10-07	"escova de dentes"