BRPI1013012A2 - identificação de pequenas moléculas reconhecidas por anticorpos em indivíduos com doenças neurodegenerativas - Google Patents

identificação de pequenas moléculas reconhecidas por anticorpos em indivíduos com doenças neurodegenerativas

Info

Publication number
BRPI1013012A2
BRPI1013012A2 BRPI1013012A BRPI1013012A BRPI1013012A2 BR PI1013012 A2 BRPI1013012 A2 BR PI1013012A2 BR PI1013012 A BRPI1013012 A BR PI1013012A BR PI1013012 A BRPI1013012 A BR PI1013012A BR PI1013012 A2 BRPI1013012 A2 BR PI1013012A2
Authority
BR
Brazil
Prior art keywords
individuals
identification
neurodegenerative diseases
small antibody
molecules
Prior art date
Application number
BRPI1013012A
Other languages
English (en)
Inventor
Dwight German
Johnnie Wilson
Reddy Moola
Rosemary Wilson
Steven Connell
Thomas Kodadek
Original Assignee
Opko Health Inc
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42269525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1013012(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Opko Health Inc, Univ Texas filed Critical Opko Health Inc
Publication of BRPI1013012A2 publication Critical patent/BRPI1013012A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI1013012A 2009-06-02 2010-06-01 identificação de pequenas moléculas reconhecidas por anticorpos em indivíduos com doenças neurodegenerativas BRPI1013012A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18326009P 2009-06-02 2009-06-02
US31865510P 2010-03-29 2010-03-29
PCT/US2010/036827 WO2010141421A1 (en) 2009-06-02 2010-06-01 Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases

Publications (1)

Publication Number Publication Date
BRPI1013012A2 true BRPI1013012A2 (pt) 2016-10-18

Family

ID=42269525

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1013012A BRPI1013012A2 (pt) 2009-06-02 2010-06-01 identificação de pequenas moléculas reconhecidas por anticorpos em indivíduos com doenças neurodegenerativas

Country Status (15)

Country Link
US (1) US9551721B2 (pt)
EP (1) EP2438444A1 (pt)
JP (1) JP5828837B2 (pt)
KR (1) KR20120122869A (pt)
CN (1) CN102439451B (pt)
AU (1) AU2010256880B2 (pt)
BR (1) BRPI1013012A2 (pt)
CA (1) CA2764153C (pt)
CL (1) CL2011002973A1 (pt)
CO (1) CO6450654A2 (pt)
IL (1) IL216689A (pt)
MX (1) MX2011012933A (pt)
RU (1) RU2566064C2 (pt)
TW (1) TWI569014B (pt)
WO (1) WO2010141421A1 (pt)

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JP2014504594A (ja) 2011-01-10 2014-02-24 オプコ ファーマシューティカルズ、エルエルシー 自己免疫疾患における抗原代用物
JP6153921B2 (ja) 2011-03-24 2017-06-28 オプコ ファーマシューティカルズ、エルエルシー ビーズまたは粒子ベースのライブラリーを用いた液体生体試料中でのバイオマーカー発見、並びに診断キットおよび治療法
EP2705180A4 (en) * 2011-05-06 2015-04-22 Elwha Llc COMPOSITIONS AND METHODS FOR IDENTIFICATION OF ANTIBODY AND LIGAND
US11360098B2 (en) 2015-09-28 2022-06-14 Quest Diagnostics Investments Llc Amyloid beta detection by mass spectrometry
CA3001065A1 (en) 2015-10-14 2017-04-20 Xiaoxi WEI Compositions and methods for reducing ice crystal formation
US11053281B2 (en) 2016-03-09 2021-07-06 Mike-Ann, Llc Peptoid affinity ligands
WO2017165438A1 (en) 2016-03-25 2017-09-28 Muralidhar Reddy Moola Combinatorial synthesis and biomarker development
CN106866794B (zh) * 2017-02-15 2020-09-08 国家纳米科学中心 一种类肽及其制备方法和应用
CN108484905A (zh) * 2018-04-16 2018-09-04 青岛科技大学 一种侧链含羧基具有ucst行为的聚类肽及其制备方法
WO2019211878A1 (en) * 2018-05-04 2019-11-07 Council Of Scientific And Industrial Research, An Indian Registered Body Incorporated Under The Registration Of Societies Act (Act Xxi Of 1860) Peptoid of formula i, pharmaceutical compositions and method for preparation thereof
CN108586579B (zh) * 2018-05-11 2021-11-30 京东方科技集团股份有限公司 一种类肽及其衍生物、盐、制备方法和用途

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Also Published As

Publication number Publication date
HK1169709A1 (en) 2013-02-01
US9551721B2 (en) 2017-01-24
CL2011002973A1 (es) 2012-03-23
US20100303805A1 (en) 2010-12-02
CA2764153C (en) 2021-07-27
IL216689A0 (en) 2012-02-29
CN102439451A (zh) 2012-05-02
JP5828837B2 (ja) 2015-12-09
CA2764153A1 (en) 2010-12-09
CO6450654A2 (es) 2012-05-31
TWI569014B (zh) 2017-02-01
TW201109662A (en) 2011-03-16
MX2011012933A (es) 2012-03-07
IL216689A (en) 2016-09-29
JP2012529053A (ja) 2012-11-15
KR20120122869A (ko) 2012-11-07
CN102439451B (zh) 2014-12-03
RU2566064C2 (ru) 2015-10-20
AU2010256880A1 (en) 2011-11-03
EP2438444A1 (en) 2012-04-11
AU2010256880B2 (en) 2015-01-22
WO2010141421A1 (en) 2010-12-09

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
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