BRPI1013201A2 - meios e métodos para reconhecer o desenvolvimento de doenças cardiovascular em um indivíduo - Google Patents

meios e métodos para reconhecer o desenvolvimento de doenças cardiovascular em um indivíduo

Info

Publication number
BRPI1013201A2
BRPI1013201A2 BRPI1013201A BRPI1013201A BRPI1013201A2 BR PI1013201 A2 BRPI1013201 A2 BR PI1013201A2 BR PI1013201 A BRPI1013201 A BR PI1013201A BR PI1013201 A BRPI1013201 A BR PI1013201A BR PI1013201 A2 BRPI1013201 A2 BR PI1013201A2
Authority
BR
Brazil
Prior art keywords
individual
iam
recognizing
development
methods
Prior art date
Application number
BRPI1013201A
Other languages
English (en)
Inventor
Sahar Eli
Domany Eytan
R Cohen Irun
Shental Noam
Original Assignee
Yeda res & development co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda res & development co ltd filed Critical Yeda res & development co ltd
Publication of BRPI1013201A2 publication Critical patent/BRPI1013201A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

meio_s e niétodos para reconhecer o desenvolvimento de doenças cardiovasculares em um individuo. um método para reconhecimento de um processo de infarto agudo do s miocárdio (iam) em um indivrduo, onde o método compreende passos de: perfis específicos de anticorpos reativos ou biomarcadores associados com a suscetibilidade a um iam, o perfil compreendendo passos de: anexando um conjunto de antígenos definidos a um substrato; obtendo um fluido biológico de espécie derivada de um indivíduo, este espécime contendo um repertório de anticorpos específicos; e ligando 10 os referidos anticorpos do e~pécime do fluido biológico ao antígeno anexado formando assim uma ligação de complexos de antígenos dos anticorpos; e analisando resultados obtidos, onde a presença dos complexos indicam o iam.
BRPI1013201A 2009-05-05 2010-05-05 meios e métodos para reconhecer o desenvolvimento de doenças cardiovascular em um indivíduo BRPI1013201A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17547209P 2009-05-05 2009-05-05
PCT/IL2010/000361 WO2010128506A2 (en) 2009-05-05 2010-05-05 Means and methods for recognizing the development of cardiovascular disease in an individual

Publications (1)

Publication Number Publication Date
BRPI1013201A2 true BRPI1013201A2 (pt) 2019-02-26

Family

ID=43050575

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1013201A BRPI1013201A2 (pt) 2009-05-05 2010-05-05 meios e métodos para reconhecer o desenvolvimento de doenças cardiovascular em um indivíduo

Country Status (6)

Country Link
US (2) US20120122720A1 (pt)
EP (1) EP2427767A4 (pt)
CN (1) CN102803965A (pt)
BR (1) BRPI1013201A2 (pt)
CA (1) CA2760903A1 (pt)
WO (1) WO2010128506A2 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2534487B1 (en) 2010-02-12 2015-11-04 Yeda Research and Development Co. Ltd. Diagnosis of systemic lupus erythematosus (sle)
WO2012058598A1 (en) * 2010-10-29 2012-05-03 The Trustees Of Columbia University In The City Of New York Methods of preventing and treating hyperlipidemia or atherosclerosis
US8652999B1 (en) 2012-07-24 2014-02-18 Dow Agrosciences, Llc. Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and a sulfonylaminocarbonyltriazolinone
US10545144B2 (en) 2013-12-31 2020-01-28 Yeda Research And Development Co., Ltd. Diagnosis of systemic lupus erythematosus using oligonucleotides antigens
EP3090263A4 (en) 2013-12-31 2017-08-23 Yeda Research and Development Co., Ltd. Methods for assaying immunological competence
CN104688187A (zh) * 2015-02-14 2015-06-10 袁玉香 心血管疾病检测装置
EP3265814B1 (en) 2015-03-01 2020-11-18 Immunarray Ltd. Diagnosis of systemic lupus erythematosus using protein, peptide and oligonucleotide antigens

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0792165A (ja) * 1993-09-21 1995-04-07 Hoechst Japan Ltd 骨粗鬆症診断剤
WO2001061349A1 (en) * 2000-02-18 2001-08-23 The University Of Tennessee Research Corporation Detection of microbial deposition and immune response at the basement membrane
EP1554577A4 (en) * 2002-09-11 2006-12-06 Univ Emory METHOD FOR ASSESSING AN ENDOTHEL ERROR FUNCTION USING AN ACUTE TRANSIENT RESPONSE TO FAT ADMINISTRATION
ES2239532B1 (es) * 2004-02-06 2006-11-01 Proyecto De Biomedicina Cima S.L. Metodo para evaluar el riesgo y la predisposicion a desarrollar una patologia relacionada con la presencia de autoanticuerpos frente a epcr.
WO2007028070A2 (en) * 2005-08-30 2007-03-08 Biosite, Inc. Use of soluble flt-1 and its fragments in cardiovascular conditions
WO2007085411A1 (en) * 2006-01-25 2007-08-02 Roche Diagnostics Gmbh Anti-troponin antibodies and cardiovascular risk
ES2700141T3 (es) * 2007-08-02 2019-02-14 Gilead Biologics Inc Anticuerpos inhibidores LOXL2 y usos de los mismos
US9140701B2 (en) * 2009-08-18 2015-09-22 The Board Of Trustees Of The Leland Stanford Junior University Fibrinogen immune complexes to diagnose and guide therapy in rheumatoid arthritis

Also Published As

Publication number Publication date
US20140336077A1 (en) 2014-11-13
WO2010128506A3 (en) 2011-10-13
EP2427767A4 (en) 2013-01-23
US20120122720A1 (en) 2012-05-17
CN102803965A (zh) 2012-11-28
US9075072B2 (en) 2015-07-07
CA2760903A1 (en) 2010-11-11
EP2427767A2 (en) 2012-03-14
WO2010128506A2 (en) 2010-11-11

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Legal Events

Date Code Title Description
B15I Others concerning applications: loss of priority

Free format text: PERDA DA PRIORIDADE US 61/175,472 DE 05/05/2009 REIVINDICADA NO PCT/IL2010/000361, CONFORME AS DISPOSICOES PREVISTAS NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 7O, ITEM 28 DO ATO NORMATIVO 128/97 E NO ART. 29 DA RESOLUCAO INPI-PR 77/2013. ESTA PERDA SE DEU PELO FATO DE O DEPOSITANTE CONSTANTE DA PETICAO DE REQUERIMENTO DO PEDIDO PCT (?YEDA RESEARCH AND DEVELOPMENT CO. LTD.?) SER DISTINTO DAQUELE QUE DEPOSITOU A PRIORIDADE REIVINDICADA E NAO FOI APRESENTADO O DOCUMENTO COMPROBATORIO DE CESSAO, CONFORME AS DISPOSICOES PREVISTAS NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 6O, ITEM 27 DO ATO NORMATIVO 128/97 E NO ART. 2 DA RESOLUCAO INPI-PR 179/2017.

B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2514 DE 12-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]