BRPI1013903A2 - tratamentos terapêuticos utilizando centaquina - Google Patents
tratamentos terapêuticos utilizando centaquinaInfo
- Publication number
- BRPI1013903A2 BRPI1013903A2 BRPI1013903A BRPI1013903A BRPI1013903A2 BR PI1013903 A2 BRPI1013903 A2 BR PI1013903A2 BR PI1013903 A BRPI1013903 A BR PI1013903A BR PI1013903 A BRPI1013903 A BR PI1013903A BR PI1013903 A2 BRPI1013903 A2 BR PI1013903A2
- Authority
- BR
- Brazil
- Prior art keywords
- centaquin
- therapeutic treatments
- treatments
- therapeutic
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000011282 treatment Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Quinoline Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17425709P | 2009-04-30 | 2009-04-30 | |
| US61/174,257 | 2009-04-30 | ||
| PCT/US2010/032942 WO2010127096A2 (en) | 2009-04-30 | 2010-04-29 | Novel therapeutic treatments using centhaquin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI1013903A2 true BRPI1013903A2 (pt) | 2016-07-19 |
| BRPI1013903B1 BRPI1013903B1 (pt) | 2020-03-03 |
Family
ID=43032771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1013903-6A BRPI1013903B1 (pt) | 2009-04-30 | 2010-04-29 | Uso de um agente adrenérgico e um antagonista de endotelina-A, composição e uso de centaquina |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20120083447A1 (pt) |
| EP (1) | EP2424529B1 (pt) |
| JP (2) | JP5498571B2 (pt) |
| CN (2) | CN102458399B (pt) |
| AU (1) | AU2010241564B2 (pt) |
| BR (1) | BRPI1013903B1 (pt) |
| CA (1) | CA2759791C (pt) |
| ES (1) | ES2614813T3 (pt) |
| PL (1) | PL2424529T3 (pt) |
| WO (1) | WO2010127096A2 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5498571B2 (ja) | 2009-04-30 | 2014-05-21 | ミッドウェスタン ユニバーシティ | センタキンを用いた新規の治療方法 |
| CN110354267A (zh) * | 2012-08-31 | 2019-10-22 | 法尔麦兹公司 | 用于低血压复苏的方法和组合物 |
| WO2016061583A1 (en) * | 2014-10-17 | 2016-04-21 | University Of Virginia Patent Foundation | Compositions and methods for treating pituitary tumors |
| JP7458032B2 (ja) * | 2018-05-03 | 2024-03-29 | ミッドウェスタン ユニバーシティ | 出血およびセンタキンによる蘇生後のエンドセリン受容体の変化 |
| CN117440812A (zh) * | 2021-05-11 | 2024-01-23 | 法尔麦兹公司 | 用于治疗冠状病毒病(covid-19)中的急性呼吸窘迫综合征(ards)的药物组合物及方法 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3954987A (en) * | 1972-12-22 | 1976-05-04 | Sandoz, Inc. | 2-Alkyl-4-substituted amino-quinazolines and nitrates thereof in the treatment of myocardial shock |
| DE2421382A1 (de) | 1974-05-03 | 1975-11-20 | Council Scient Ind Res | 1-substituierte 4-(beta-2-chinolylaethyl)- piperazine und deren 1,2,3,4-tetrahydrochinolinanaloge |
| JPS604186B2 (ja) | 1974-05-13 | 1985-02-01 | カウンシル、オブ、サイエンテイフイツク、アンド、インダストリアルリサーチ | １―ｍ―トリル―４―（Ｂ―２―キノリエチル）―ピペラジンの製造法 |
| US3983121A (en) | 1974-07-01 | 1976-09-28 | Council Of Scientific And Industrial Research | 1-Substituted 4-(β-2-quinolylethyl)piperazines and 1,2,3,4-tetrahydroquinolyl-ethyl analogues thereof |
| DE2557784C2 (de) * | 1975-12-22 | 1986-04-17 | Hoechst Ag, 6230 Frankfurt | Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate |
| US4761417A (en) * | 1982-05-14 | 1988-08-02 | Maroko Peter R | Compounds, compositions and method of treatments for improving circulatory performance |
| EP0126327A1 (en) | 1983-04-26 | 1984-11-28 | Frank J. Macri | Norepinephrine potentiated pharmaceutical composition, ophthalmic solution and kit containing the same |
| US5055470A (en) | 1989-06-01 | 1991-10-08 | Bristol-Myers Squibb Co. | Method of treatment of ischemia in brain |
| US5922681A (en) | 1992-09-14 | 1999-07-13 | Warner-Lambert Company | Endothelin antagonists |
| US20040063719A1 (en) * | 1998-08-26 | 2004-04-01 | Queen's University At Kingston | Combination therapy using antihypertensive agents and endothelin antagonists |
| US6545048B1 (en) | 1999-06-29 | 2003-04-08 | California Institute Of Technology | Compositions and methods of treating cancer using compositions comprising an inhibitor or endothelin receptor activity |
| US6113915A (en) | 1999-10-12 | 2000-09-05 | Allergan Sales, Inc. | Methods for treating pain |
| US6369114B1 (en) | 1999-11-30 | 2002-04-09 | Institute Of Critical Care Medicine | Administration of an α2-adrenergic receptor agonist to enhance cardiopulmonary resuscitation |
| GB0013378D0 (en) | 2000-06-01 | 2000-07-26 | Glaxo Group Ltd | Use of therapeutic benzamide derivatives |
| SE0004455D0 (sv) | 2000-12-01 | 2000-12-01 | Milos Pekny | Method for neuron regeneration in the central nervous system |
| WO2002049630A2 (en) | 2000-12-21 | 2002-06-27 | Bristol-Myers Squibb Company | Method for preventing or treating pain by administering an endothelin antagonist |
| US20030232787A1 (en) | 2001-05-08 | 2003-12-18 | Dooley David James | Combinations of an endothelin receptor antagonist and an antiepileptic compound having pain alleviating properties or analgesic |
| US20030104976A1 (en) | 2001-07-23 | 2003-06-05 | Gudarz Davar | Analgesic methods using endothelin receptor ligands |
| US7030082B2 (en) | 2001-09-07 | 2006-04-18 | Nobex Corporation | Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith |
| US7973064B2 (en) * | 2001-11-27 | 2011-07-05 | The Board Of Trustees Of The University Of Illinois | Method and composition for potentiating an opiate analgesic |
| US7351692B2 (en) * | 2002-06-19 | 2008-04-01 | The Board Of Trustees Of The University Of Illinois | Method and composition for potentiating the antipyretic action of a nonopioid analgesic |
| JP2006508086A (ja) | 2002-10-24 | 2006-03-09 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ | 固形腫瘍を予防および治療するための方法および組成物 |
| GB0226931D0 (en) | 2002-11-19 | 2002-12-24 | Astrazeneca Ab | Chemical compounds |
| DK1583541T3 (da) | 2002-11-20 | 2011-04-11 | Neuronova Ab | Forbindelser og fremgangsmåder til at øge neurogenese |
| CN101005828B (zh) | 2004-06-17 | 2012-01-11 | 维尔恩公司 | 用于经粘膜递送活性成分的包含粘膜粘附蛋白和所述活性物质的组合物 |
| WO2008043102A2 (en) | 2006-10-06 | 2008-04-10 | Transition Therapeutics Inc. | Vasoactive intestinal polypeptide compositions |
| EP1931199A4 (en) | 2005-08-31 | 2009-07-29 | Univ Tennessee Res Foundation | COMBATING NURSE DISEASE, BURNS, WOUNDS AND BACKMARK INJURIES WITH SELECTIVE ANDROGEN RECEPTOR MODULATORS |
| JP4976412B2 (ja) | 2005-12-01 | 2012-07-18 | ベー・エル・アー・ハー・エム・エス・ゲーエムベーハー | エンドセリン、エンドセリンアゴニスト及びアドレノメジュリンアンタゴニストによる危篤患者の診断及び治療のための方法 |
| AU2007230887A1 (en) | 2006-03-23 | 2007-10-04 | Amylin Pharmaceuticals, Inc. | Endothelin and endothelin receptor agonists in the treatment of metabolic diseases |
| CA2696398C (en) | 2007-08-21 | 2018-05-08 | Midwestern University | Methods for treatment of stroke or cerebrovascular accidents using an etb receptor agonist |
| US20100189802A1 (en) | 2007-08-21 | 2010-07-29 | Scott And White Memorial Hospital And Scott, Sherwood, And Brindley Foundation | Method for treatment of vascular hyperpermeability |
| CN101374259B (zh) | 2007-08-22 | 2012-08-08 | 华为技术有限公司 | 实现多媒体彩铃和多媒体彩像业务的方法和装置 |
| EP2165706A1 (en) | 2008-09-18 | 2010-03-24 | BioAlliance Pharma | Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers. |
| JP5498571B2 (ja) | 2009-04-30 | 2014-05-21 | ミッドウェスタン ユニバーシティ | センタキンを用いた新規の治療方法 |
| BRPI1013904A2 (pt) | 2009-04-30 | 2016-07-19 | Univ Midwestern | método e composição para tratar cetoacidose diabética |
| WO2011159854A1 (en) | 2010-06-17 | 2011-12-22 | Janssen Pharmaceutica Nv | Cyclohexyl-azetidinyl antagonists of ccr2 |
| KR101418941B1 (ko) | 2011-04-04 | 2014-07-15 | 서울대학교병원 | 엔도텔린을 유효성분으로 함유하는 허혈성질환 치료용 조성물 |
| CN110354267A (zh) | 2012-08-31 | 2019-10-22 | 法尔麦兹公司 | 用于低血压复苏的方法和组合物 |
| ES2825101T3 (es) | 2013-07-08 | 2021-05-14 | Univ Midwestern | Composiciones y métodos para el tratamiento de trastornos neuropsiquiátricos usando un agonista del receptor de la endotelina B |
| JP7458032B2 (ja) | 2018-05-03 | 2024-03-29 | ミッドウェスタン ユニバーシティ | 出血およびセンタキンによる蘇生後のエンドセリン受容体の変化 |
-
2010
- 2010-04-29 JP JP2012508721A patent/JP5498571B2/ja active Active
- 2010-04-29 EP EP10770318.3A patent/EP2424529B1/en active Active
- 2010-04-29 CA CA2759791A patent/CA2759791C/en active Active
- 2010-04-29 BR BRPI1013903-6A patent/BRPI1013903B1/pt active IP Right Grant
- 2010-04-29 ES ES10770318.3T patent/ES2614813T3/es active Active
- 2010-04-29 AU AU2010241564A patent/AU2010241564B2/en active Active
- 2010-04-29 WO PCT/US2010/032942 patent/WO2010127096A2/en not_active Ceased
- 2010-04-29 PL PL10770318T patent/PL2424529T3/pl unknown
- 2010-04-29 US US13/266,205 patent/US20120083447A1/en not_active Abandoned
- 2010-04-29 CN CN201080029672.5A patent/CN102458399B/zh active Active
- 2010-04-29 CN CN201410085543.8A patent/CN103989682B/zh active Active
-
2014
- 2014-03-07 JP JP2014044799A patent/JP5727642B2/ja active Active
-
2017
- 2017-09-25 US US15/714,008 patent/US10828368B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10828368B2 (en) | 2020-11-10 |
| ES2614813T3 (es) | 2017-06-02 |
| JP5727642B2 (ja) | 2015-06-03 |
| US20120083447A1 (en) | 2012-04-05 |
| US20180085461A1 (en) | 2018-03-29 |
| EP2424529B1 (en) | 2016-12-28 |
| CN102458399B (zh) | 2014-04-23 |
| BRPI1013903B1 (pt) | 2020-03-03 |
| PL2424529T3 (pl) | 2017-06-30 |
| EP2424529A4 (en) | 2012-11-28 |
| JP2012525422A (ja) | 2012-10-22 |
| EP2424529A2 (en) | 2012-03-07 |
| CN102458399A (zh) | 2012-05-16 |
| WO2010127096A3 (en) | 2011-03-24 |
| AU2010241564A1 (en) | 2011-11-17 |
| CN103989682A (zh) | 2014-08-20 |
| WO2010127096A2 (en) | 2010-11-04 |
| CA2759791C (en) | 2018-04-10 |
| AU2010241564B2 (en) | 2014-07-31 |
| CN103989682B (zh) | 2016-03-30 |
| JP5498571B2 (ja) | 2014-05-21 |
| CA2759791A1 (en) | 2010-11-04 |
| JP2014141502A (ja) | 2014-08-07 |
| AU2010241564A2 (en) | 2012-10-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE526024T1 (de) | Fluvoxamin vermeidende pirfenidontheraphy | |
| BRPI0916931A2 (pt) | agentes terapêuticos | |
| FI20105569L (fi) | Kehonsisäinen hoitolaite | |
| EP2296593A4 (en) | MEDICAL HEAD COVER | |
| DE602009000539D1 (de) | Strahlentherapiegerät | |
| DK2330887T3 (da) | Behandlingsindretning | |
| DE112010004110T8 (de) | Neue parasitentherapie | |
| EP2432539A4 (en) | Hyperthermia assisted radiation therapy | |
| BRPI0917684A2 (pt) | método terapêutico homeopático | |
| EP3381471C0 (en) | PAIN TREATMENT | |
| HRP20160929T1 (hr) | Terapijski režimi | |
| EP2415408A4 (en) | Treatment device | |
| BRPI0818598A2 (pt) | agentes terapêuticos - 802 | |
| BRPI1010516A2 (pt) | Métodos de tratamento de edema relacionados à isquemia-reperfusão | |
| BRPI1007543A2 (pt) | tratamento de psoríase | |
| HRP20160577T1 (hr) | Liječenje osteoartritisa | |
| PL2424529T3 (pl) | Nowe postępowania terapeutyczne z zastosowaniem centakwiny | |
| EP2309854A4 (en) | ACCELERATED THERAPY: | |
| BRPI0909764A2 (pt) | compostos terapêuticos | |
| DK2694056T3 (da) | Terapeutisk behandling | |
| EP2266520A4 (en) | Massage machine | |
| BRPI0906879A2 (pt) | Compostos terapêuticos | |
| EP2490704A4 (en) | THERAPEUTIC COMPOSITION | |
| BRPI0911543A2 (pt) | arilciclopentenos substituídos como agentes terapêuticos | |
| FR2937843B1 (fr) | Paravent medical |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11N | Dismissal: publication cancelled [chapter 11.14 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 29/04/2010, OBSERVADAS AS CONDICOES LEGAIS. |