BRPI1013957A2 - método para produzir exossomas moduladores imunes específicos, composição farmacêutica, exossoma, e, método para tratar um indivíduo em necessidade do tratamento. - Google Patents

método para produzir exossomas moduladores imunes específicos, composição farmacêutica, exossoma, e, método para tratar um indivíduo em necessidade do tratamento.

Info

Publication number: BRPI1013957A2
Authority: BR; Brazil
Prior art keywords: exosome; exosomes; treating; individual; treatment
Prior art date: 2009-07-02

Application number

BRPI1013957A

Other languages

English (en)

Inventor

Susanne Gabrielsson

Original Assignee

Ith Immune Therapy Holdings Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-07-02

Filing date

2010-07-02

Publication date

2016-04-05

2010-07-02 Application filed by Ith Immune Therapy Holdings Ab filed Critical Ith Immune Therapy Holdings Ab

2016-04-05 Publication of BRPI1013957A2 publication Critical patent/BRPI1013957A2/pt

Links

210000001808 exosome Anatomy 0.000 title 2
230000002519 immonomodulatory effect Effects 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Mycology (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Cell Biology (AREA)
Virology (AREA)
Natural Medicines & Medicinal Plants (AREA)
Communicable Diseases (AREA)
Botany (AREA)
Transplantation (AREA)
Alternative & Traditional Medicine (AREA)
Biotechnology (AREA)
Pulmonology (AREA)
Medical Informatics (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)

BRPI1013957A 2009-07-02 2010-07-02 método para produzir exossomas moduladores imunes específicos, composição farmacêutica, exossoma, e, método para tratar um indivíduo em necessidade do tratamento. BRPI1013957A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0900904		2009-07-02
PCT/EP2010/003946 WO2011000551A1 (en)	2009-07-02	2010-07-02	Exosome based treatment of cancer

Publications (1)

Publication Number	Publication Date
BRPI1013957A2 true BRPI1013957A2 (pt)	2016-04-05

Family

ID=42989304

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI1013957A BRPI1013957A2 (pt)	2009-07-02	2010-07-02	método para produzir exossomas moduladores imunes específicos, composição farmacêutica, exossoma, e, método para tratar um indivíduo em necessidade do tratamento.

Country Status (14)

Country	Link
US (1)	US8932855B2 (pt)
EP (1)	EP2448595B1 (pt)
JP (1)	JP2012531391A (pt)
KR (1)	KR20120081972A (pt)
CN (2)	CN107412755A (pt)
AU (1)	AU2010268367B2 (pt)
BR (1)	BRPI1013957A2 (pt)
CA (1)	CA2766833A1 (pt)
IL (1)	IL217291A0 (pt)
IN (1)	IN2012DN00423A (pt)
MX (1)	MX2011013452A (pt)
RU (1)	RU2012103482A (pt)
WO (1)	WO2011000551A1 (pt)
ZA (1)	ZA201109226B (pt)

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WO2013070324A1 (en)	2011-11-07	2013-05-16	University Of Louisville Research Foundation, Inc.	Edible plant-derived microvesicle compositions for diagnosis and treatment of disease
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EP2833893B1 (en) *	2012-04-03	2018-08-29	Reneuron Limited	Stem cell microparticles
WO2013158913A1 (en) *	2012-04-18	2013-10-24	Rhode Island Hospital, A Lifespan-Partner	Treating cancer
EP2687219A1 (en) *	2012-07-18	2014-01-22	Universität Duisburg-Essen	Use of preparations comprising exosomes derived from mesenchymal stem cells (MSCs) in the prevention and therapy of inflammatory conditions
US9950074B2 (en)	2012-10-12	2018-04-24	Georg-August-Universität Göttingen Stiftung Öffenlichen Rechts, Universitätsmedizin	Composition and delivery vehicle for active agents and methods therefor
WO2014078272A1 (en)	2012-11-13	2014-05-22	Mayo Foundation For Medical Education And Research	Methods and materials for assessing immune system profiles
WO2014159662A1 (en)	2013-03-13	2014-10-02	University Of Miami	Method for isolation and purification of microvesicles from cell culture supernatants and biological fluids
MY177482A (en)	2013-03-13	2020-09-16	Zhong Li	Microvesicle and method for producing the same
US12558316B2 (en)	2013-03-13	2026-02-24	University Of Miami	Methods and compositions for the treatment of epidermolysis bullosa
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CN104726410B (zh) *	2013-12-23	2019-09-17	浙江大学	一种具有免疫抑制功能的外排体及其应用
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AU2016327573B2 (en)	2015-09-22	2022-07-14	Trustees Of Boston University	Multiplexed phenotyping of nanovesicles
WO2017124000A1 (en)	2016-01-14	2017-07-20	The Regents Of The University Of California	3d-exoquant method for the analysis of surface molecules and quantification of tissue-specific exosomes in biological fluids
WO2017136676A1 (en)	2016-02-05	2017-08-10	Nanoview Diagnostics Inc.	Detection of exosomes having surface markers
WO2017189281A1 (en)	2016-04-27	2017-11-02	The Regents Of The University Of Michigan	C3d cellular and acellular vaccines for the prevention and treatment of cancer
CN105861430B (zh) *	2016-04-29	2019-07-23	南京大学	一种外泌体、外泌体的制备方法及其在制备治疗脓毒症药物或者制剂中的应用
AU2017335084B2 (en) *	2016-09-30	2023-06-29	Ilias Biologics Inc.	Compositions containing protein loaded exosome and methods for preparing and delivering the same
CN108324735B (zh) *	2017-01-20	2024-02-09	李莉	用于疾病治疗的胞外体制剂及其应用
US11760975B2 (en) *	2017-03-31	2023-09-19	Wisconsin Alumi Research Foundation	Generation of therapeutic cells using extracellular components of target organs
US10815520B2 (en)	2017-04-07	2020-10-27	University Of Louisville Research Foundation, Inc.	Nanovesicles, methods, and systems for diagnosis and prognosis of cancer
US11531034B2 (en) *	2017-05-08	2022-12-20	Beckman Coulter, Inc.	Compositions and methods for lysis of red blood cells
EP3438250B1 (en) *	2017-07-31	2022-12-07	Rheinische Friedrich-Wilhelms-Universität Bonn	Cell derived extracellular vesicles for the treatment of diseases
CN111527199A (zh)	2017-11-16	2020-08-11	得克萨斯大学体系董事会	用于制备来源于msc的外泌体的方法
WO2019104242A1 (en)	2017-11-22	2019-05-31	University Of Louisville Research Foundation, Inc.	Edible plant-derived nanoparticles for regulation of gut microbiota
CN107988153B (zh) *	2017-12-15	2021-05-18	英科博雅生命科技有限公司	人脐带血间充质干细胞源分离外泌体的方法和使用的试剂
CA3093856A1 (en) *	2018-03-12	2019-09-19	Board Of Regents, The University Of Texas System	Immuno-exosomes and methods of use thereof
EP3775258A4 (en)	2018-03-28	2022-01-26	Board of Regents, The University of Texas System	IDENTIFICATION OF EPIGENETIC ALTERATIONS IN DNA ISOLATED FROM EXOSOMES
CN108587998B (zh) *	2018-05-17	2021-05-18	浙江大学	一种外泌体、外泌体的制备方法及其在制备皮肤浅表性肿瘤的药物中的应用
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CN111840528A (zh) *	2020-06-17	2020-10-30	河北大学	外泌体联合免疫检查点阻断剂的肿瘤疫苗及其制备方法
KR102559516B1 (ko) *	2020-08-31	2023-07-26	경희대학교 산학협력단	우유 엑소좀을 포함하는 갈색지방화 유도용 조성물
CN113960313B (zh) *	2021-12-22	2022-04-12	上海思路迪医学检验所有限公司	一种外泌体alk融合蛋白磁免疫化学发光检测试剂盒
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2010
- 2010-07-02 KR KR1020127002892A patent/KR20120081972A/ko not_active Withdrawn
- 2010-07-02 CA CA2766833A patent/CA2766833A1/en not_active Abandoned
- 2010-07-02 CN CN201710145377.XA patent/CN107412755A/zh active Pending
- 2010-07-02 MX MX2011013452A patent/MX2011013452A/es not_active Application Discontinuation
- 2010-07-02 RU RU2012103482/15A patent/RU2012103482A/ru not_active Application Discontinuation
- 2010-07-02 WO PCT/EP2010/003946 patent/WO2011000551A1/en not_active Ceased
- 2010-07-02 AU AU2010268367A patent/AU2010268367B2/en not_active Ceased
- 2010-07-02 CN CN2010800300523A patent/CN102470167A/zh active Pending
- 2010-07-02 US US13/381,429 patent/US8932855B2/en active Active
- 2010-07-02 BR BRPI1013957A patent/BRPI1013957A2/pt not_active Application Discontinuation
- 2010-07-02 JP JP2012516589A patent/JP2012531391A/ja active Pending
- 2010-07-02 EP EP10732289.3A patent/EP2448595B1/en active Active
2011
- 2011-12-14 ZA ZA2011/09226A patent/ZA201109226B/en unknown
- 2011-12-29 IL IL217291A patent/IL217291A0/en unknown
2012
- 2012-01-16 IN IN423DEN2012 patent/IN2012DN00423A/en unknown

Also Published As

Publication number	Publication date
RU2012103482A (ru)	2013-08-10
EP2448595B1 (en)	2017-06-14
US20120183575A1 (en)	2012-07-19
JP2012531391A (ja)	2012-12-10
ZA201109226B (en)	2014-05-28
IN2012DN00423A (pt)	2015-05-15
US8932855B2 (en)	2015-01-13
EP2448595A1 (en)	2012-05-09
MX2011013452A (es)	2012-04-30
AU2010268367B2 (en)	2016-10-20
KR20120081972A (ko)	2012-07-20
AU2010268367A1 (en)	2012-01-19
CN102470167A (zh)	2012-05-23
WO2011000551A1 (en)	2011-01-06
CA2766833A1 (en)	2011-01-06
CN107412755A (zh)	2017-12-01
IL217291A0 (en)	2012-02-29

Legal Events

Date	Code	Title	Description
2016-05-31	B11A	Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
2016-08-16	B11Y	Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]

Publication	Publication Date	Title
BRPI1013957A2 (pt)	2016-04-05	método para produzir exossomas moduladores imunes específicos, composição farmacêutica, exossoma, e, método para tratar um indivíduo em necessidade do tratamento.
BR112014023937A2 (pt)	2018-04-17	composição farmacêutica, agente farmacêutico de combinação e método de tratamento
SI2729151T1 (sl)	2021-06-30	Farmacevtski sestavek, postopki za zdravljenje in njihove uporabe
MX2021015735A (es)	2022-06-09	Composiciones de nucleasa terapeuticas y metodos.
BR112013014583A2 (pt)	2016-09-20	composição farmacêutica, e, métodos para o tratamento de inflamação, para o tratamento da dor, e para preparar 3-metanossulfonilpropionitrila
CR20120202A (es)	2012-06-12	Métodos y composiciones para tratar cáncer
SI2986304T1 (sl)	2022-04-29	Farmacevtski sestavek, postopki za zdravljenje in njegove uporabe
BR112013009708A2 (pt)	2016-07-19	aparelhos, métodos e composições para tratamento endodôntico
BR112014002621A2 (pt)	2017-12-12	anticorpo, composição farmacêutica, combinação farmacêutica, dna e método de tratamento
EA201291031A1 (ru)	2013-04-30	Способ лечения ожирения с применением антиоксидантных модуляторов воспаления
HK1220980A1 (zh)	2017-05-19	用於治疗庞贝氏症的方法和组合物
PL2672966T3 (pl)	2017-05-31	Kompozycja farmaceutyczna, sposoby leczenia i jej zastosowania
BR112014025726A2 (pt)	2017-10-24	mecanismo, sistema e método para tratamento endodôntico
AP2012006135A0 (en)	2012-02-29	Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof.
BR112015015977A2 (pt)	2018-05-15	aparelho com movimento elíptico para limpeza de pele, estimulação e distribuição de tratamentos
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