BRPI1015155A2 - regulação do crescimento ósseo usando zeólito em combinação com substitutos de enxerto ósseo. - Google Patents

regulação do crescimento ósseo usando zeólito em combinação com substitutos de enxerto ósseo.

Info

Publication number
BRPI1015155A2
BRPI1015155A2 BRPI1015155A BRPI1015155A BRPI1015155A2 BR PI1015155 A2 BRPI1015155 A2 BR PI1015155A2 BR PI1015155 A BRPI1015155 A BR PI1015155A BR PI1015155 A BRPI1015155 A BR PI1015155A BR PI1015155 A2 BRPI1015155 A2 BR PI1015155A2
Authority
BR
Brazil
Prior art keywords
bone
zeolite
regulation
combination
graft substitutes
Prior art date
Application number
BRPI1015155A
Other languages
English (en)
Inventor
Johns Derrick
Halfiz Jami
Geck Matthew
Whang Peter
Original Assignee
Difusion Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Difusion Tech Inc filed Critical Difusion Tech Inc
Publication of BRPI1015155A2 publication Critical patent/BRPI1015155A2/pt
Publication of BRPI1015155A8 publication Critical patent/BRPI1015155A8/pt
Publication of BRPI1015155B1 publication Critical patent/BRPI1015155B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
BRPI1015155-9A 2009-04-01 2010-03-30 Substituto de enxerto ósseo, implante e dispositivo intracorpóreo, bem como métodos para modulação da mineralização e formação óssea, para promover a fusão espinhal e para sobreregular seletivamente a expressão de proteínas morfogenéticas ósseas BRPI1015155B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21156909P 2009-04-01 2009-04-01
US61/211.569 2009-04-01
US30914310P 2010-03-01 2010-03-01
US61/309.143 2010-03-01
PCT/US2010/029180 WO2010114827A1 (en) 2009-04-01 2010-03-30 Regulation of bone growth using zeolite in combination with bone graft substitutes

Publications (3)

Publication Number Publication Date
BRPI1015155A2 true BRPI1015155A2 (pt) 2017-06-27
BRPI1015155A8 BRPI1015155A8 (pt) 2018-01-09
BRPI1015155B1 BRPI1015155B1 (pt) 2022-07-19

Family

ID=42828660

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1015155-9A BRPI1015155B1 (pt) 2009-04-01 2010-03-30 Substituto de enxerto ósseo, implante e dispositivo intracorpóreo, bem como métodos para modulação da mineralização e formação óssea, para promover a fusão espinhal e para sobreregular seletivamente a expressão de proteínas morfogenéticas ósseas

Country Status (7)

Country Link
US (1) US20120141599A1 (pt)
EP (2) EP2942068A1 (pt)
KR (1) KR20120006997A (pt)
CN (1) CN102387782B (pt)
BR (1) BRPI1015155B1 (pt)
RU (1) RU2529791C2 (pt)
WO (1) WO2010114827A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2504041B1 (en) 2009-11-25 2017-04-12 Difusion Technologies Inc. Post-charging of zeolite doped plastics with antimicrobial metal ions
BR112012016027B1 (pt) 2009-12-11 2019-01-15 Difusion Technologies, Inc. método de produção de implantes antimicrobianos de polieteretercetona
EP2523672B1 (en) 2010-01-15 2016-07-13 Rutgers, the State University of New Jersey Use of vanadium compounds to accelerate bone healing
US8673018B2 (en) * 2010-02-05 2014-03-18 AMx Tek LLC Methods of using water-soluble inorganic compounds for implants
MX2012012710A (es) 2010-05-07 2013-02-26 Difusion Technologies Inc Implantes medicos con hidrofilicidad incrementada.
US20140322292A1 (en) 2010-12-10 2014-10-30 Rutgers, The State University Of New Jersey Insulin-mimetics as therapeutic adjuncts for bone regeneration
US9931348B2 (en) 2011-07-06 2018-04-03 Rutgers, The State University Of New Jersey Vanadium compounds as therapeutic adjuncts for cartilage injury and repair
EP2785358B1 (en) * 2011-11-29 2022-06-01 Rutgers, the State University of New Jersey Insulin-mimetics as therapeutic adjuncts for bone regeneration
US10207027B2 (en) 2012-06-11 2019-02-19 Globus Medical, Inc. Bioactive bone graft substitutes
US9585764B2 (en) * 2012-07-26 2017-03-07 Warsaw Orthopedic, Inc. Bone implant device
CN102793950A (zh) * 2012-08-10 2012-11-28 谭红略 一种具有药物长效缓释特性的复合硫酸钙骨充填材料及其制备方法和应用
AU2013334111A1 (en) * 2012-10-25 2015-05-28 Rutgers, The State University Of New Jersey Insulin-mimetic local therapeutic adjuncts for enhancing spinal fusion
WO2016127253A1 (en) * 2015-02-09 2016-08-18 Spatafora Michael Method and system for enhancing the activity of bone morphogenetic proteins
US11439726B2 (en) 2018-12-03 2022-09-13 Osseomimetic, LLC Surgical implants
CN109568563B (zh) * 2019-02-02 2023-01-17 北京胜泰生物医药科技有限公司 一种沸石负载天然提取物的组合物及其制备方法
US20210402052A1 (en) 2020-06-30 2021-12-30 Difusion, Inc. Medical Implants And Methods Of Manufacture

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59133235A (ja) 1983-01-21 1984-07-31 Kanebo Ltd 殺菌性ポリマー組成物及びその製造法
GB2190383B (en) * 1986-04-08 1990-03-28 Dentsply Ltd Glass/poly (carboxylic acid)cement compositions
JP2529710B2 (ja) 1987-12-28 1996-09-04 日産自動車株式会社 変速機の油圧制御装置
US5256390A (en) 1990-07-03 1993-10-26 Ethyl Corporation Biocidal zeolite particles
JPH05124919A (ja) * 1991-11-05 1993-05-21 Sangi Co Ltd 抗菌性セラミツクス
US6471993B1 (en) * 1997-08-01 2002-10-29 Massachusetts Institute Of Technology Three-dimensional polymer matrices
WO1999007326A2 (en) * 1997-08-11 1999-02-18 The University Of Toronto Innovations Foundation Antimicrobial cement compositions
US6582715B1 (en) * 1999-04-27 2003-06-24 Agion Technologies, Inc. Antimicrobial orthopedic implants
AU2003222551B2 (en) * 2002-04-09 2006-02-23 Straumann Holding Ag Medical prosthetic devices having improved biocompatibility
FR2848856B1 (fr) * 2002-12-24 2007-05-25 Cadorel Catherine Materiau a usage medical ou veterinaire, son procede d'obtention et ses applications
US20050203529A1 (en) * 2004-03-03 2005-09-15 Boehm Frank H.Jr. Minimally-invasive method for performing spinal fusion and bone graft capsule for facilitating the same
DE602006018023D1 (de) * 2005-08-08 2010-12-16 Angstrom Medica Inc Zementprodukte sowie verfahren zu deren herstellung und verwendung
WO2007056671A1 (en) * 2005-11-02 2007-05-18 Osteotech, Inc. Hemostatic bone graft
US20080033572A1 (en) * 2006-08-03 2008-02-07 Ebi L.P. Bone graft composites and methods of treating bone defects
WO2008104964A2 (en) * 2007-02-26 2008-09-04 University Of Limerick A synthetic bone graft
WO2008122594A2 (en) * 2007-04-05 2008-10-16 Cinvention Ag Partially biodegradable therapeutic implant for bone and cartilage repair

Also Published As

Publication number Publication date
EP2413900A1 (en) 2012-02-08
EP2942068A1 (en) 2015-11-11
BRPI1015155A8 (pt) 2018-01-09
EP2413900A4 (en) 2014-03-12
WO2010114827A1 (en) 2010-10-07
US20120141599A1 (en) 2012-06-07
CN102387782A (zh) 2012-03-21
BRPI1015155B1 (pt) 2022-07-19
HK1167825A1 (en) 2012-12-14
RU2529791C2 (ru) 2014-09-27
KR20120006997A (ko) 2012-01-19
RU2011144020A (ru) 2013-05-10
CN102387782B (zh) 2013-10-30

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: A61K 9/00

Ipc: A61L 27/02 (2000.01), A61L 27/22 (2000.01), A61L 2

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/03/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 15A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2822 DE 04-02-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.