BRPI1102869A2 - Método de utilização da membrana de celulose bacteriana intra articular sobre superfície lesada de patela - Google Patents
Método de utilização da membrana de celulose bacteriana intra articular sobre superfície lesada de patela Download PDFInfo
- Publication number
- BRPI1102869A2 BRPI1102869A2 BRPI1102869-6A BRPI1102869A BRPI1102869A2 BR PI1102869 A2 BRPI1102869 A2 BR PI1102869A2 BR PI1102869 A BRPI1102869 A BR PI1102869A BR PI1102869 A2 BRPI1102869 A2 BR PI1102869A2
- Authority
- BR
- Brazil
- Prior art keywords
- membrane
- articular
- bacterial cellulose
- patella
- cellulose membrane
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 42
- 239000012528 membrane Substances 0.000 title claims abstract description 38
- 229920002749 Bacterial cellulose Polymers 0.000 title claims abstract description 16
- 239000005016 bacterial cellulose Substances 0.000 title claims abstract description 16
- 210000000526 facies patellaris femoris Anatomy 0.000 title 1
- 239000000463 material Substances 0.000 claims abstract description 18
- 210000004417 patella Anatomy 0.000 claims abstract description 11
- 210000001519 tissue Anatomy 0.000 claims description 23
- 241000589220 Acetobacter Species 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 210000000845 cartilage Anatomy 0.000 claims description 3
- 229920002674 hyaluronan Polymers 0.000 claims description 3
- 238000004321 preservation Methods 0.000 claims description 3
- 241000894006 Bacteria Species 0.000 claims description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 2
- 239000005708 Sodium hypochlorite Substances 0.000 claims description 2
- 239000008280 blood Substances 0.000 claims description 2
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- 210000002449 bone cell Anatomy 0.000 claims description 2
- 239000012153 distilled water Substances 0.000 claims description 2
- 235000021395 porridge Nutrition 0.000 claims description 2
- 239000011780 sodium chloride Substances 0.000 claims description 2
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 claims description 2
- 229940036220 synvisc Drugs 0.000 claims description 2
- 238000005406 washing Methods 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 101150103171 DARS1 gene Proteins 0.000 claims 1
- 210000003321 cartilage cell Anatomy 0.000 claims 1
- 210000003041 ligament Anatomy 0.000 abstract description 15
- 210000002435 tendon Anatomy 0.000 abstract description 11
- 210000003127 knee Anatomy 0.000 abstract description 8
- 210000000281 joint capsule Anatomy 0.000 abstract description 4
- 210000001361 achilles tendon Anatomy 0.000 abstract description 3
- 210000000426 patellar ligament Anatomy 0.000 abstract description 2
- 210000001264 anterior cruciate ligament Anatomy 0.000 description 10
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- 230000006378 damage Effects 0.000 description 8
- 208000027418 Wounds and injury Diseases 0.000 description 7
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- 241001465754 Metazoa Species 0.000 description 5
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- 238000009864 tensile test Methods 0.000 description 4
- 239000000835 fiber Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 208000025674 Anterior Cruciate Ligament injury Diseases 0.000 description 2
- 229920000049 Carbon (fiber) Polymers 0.000 description 2
- 206010017577 Gait disturbance Diseases 0.000 description 2
- 206010054949 Metaplasia Diseases 0.000 description 2
- 208000021945 Tendon injury Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
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- 206010003246 arthritis Diseases 0.000 description 2
- 210000001188 articular cartilage Anatomy 0.000 description 2
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- 230000015689 metaplastic ossification Effects 0.000 description 2
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 201000004595 synovitis Diseases 0.000 description 2
- 229920002994 synthetic fiber Polymers 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241001137901 Centropomus undecimalis Species 0.000 description 1
- 108010035532 Collagen Chemical class 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 229920004934 Dacron® Polymers 0.000 description 1
- 229920000544 Gore-Tex Polymers 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010060820 Joint injury Diseases 0.000 description 1
- 208000016593 Knee injury Diseases 0.000 description 1
- 208000034693 Laceration Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 241000282898 Sus scrofa Species 0.000 description 1
- 230000016571 aggressive behavior Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 210000001306 articular ligament Anatomy 0.000 description 1
- 230000003416 augmentation Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000022159 cartilage development Effects 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920001436 collagen Chemical class 0.000 description 1
- 210000000795 conjunctiva Anatomy 0.000 description 1
- 230000023753 dehiscence Effects 0.000 description 1
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- 206010016256 fatigue Diseases 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 230000005021 gait Effects 0.000 description 1
- 244000144993 groups of animals Species 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 229940072322 hylan Drugs 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000028709 inflammatory response Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
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- 230000000391 smoking effect Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000002303 tibia Anatomy 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3637—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the origin of the biological material other than human or animal, e.g. plant extracts, algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/3662—Ligaments, tendons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/10—Materials or treatment for tissue regeneration for reconstruction of tendons or ligaments
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Vascular Medicine (AREA)
- Mycology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- Biotechnology (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI1102869-6A BRPI1102869A2 (pt) | 2011-06-10 | 2011-06-10 | Método de utilização da membrana de celulose bacteriana intra articular sobre superfície lesada de patela |
| PCT/BR2012/000179 WO2012167341A1 (fr) | 2011-06-10 | 2012-06-06 | Procédé d'utilisation de membrane de cellulose bactérienne intra-articulaire sur surface lésée de rotule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI1102869-6A BRPI1102869A2 (pt) | 2011-06-10 | 2011-06-10 | Método de utilização da membrana de celulose bacteriana intra articular sobre superfície lesada de patela |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1102869A2 true BRPI1102869A2 (pt) | 2015-08-04 |
Family
ID=47295283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1102869-6A BRPI1102869A2 (pt) | 2011-06-10 | 2011-06-10 | Método de utilização da membrana de celulose bacteriana intra articular sobre superfície lesada de patela |
Country Status (2)
| Country | Link |
|---|---|
| BR (1) | BRPI1102869A2 (fr) |
| WO (1) | WO2012167341A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116492518A (zh) * | 2023-05-12 | 2023-07-28 | 四川大学 | 一种功能等级双层膜及其制备方法与应用 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963777B (zh) * | 2016-07-08 | 2019-09-10 | 福建师范大学 | 一种细菌纤维素膜组织工程化人工肌腱支架的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800753B2 (en) * | 2001-09-04 | 2004-10-05 | University Of Iowa Research Foundation | Regenerated cellulose and oxidized cellulose membranes as potential biodegradable platforms for drug delivery and tissue engineering |
| US20040078090A1 (en) * | 2002-10-18 | 2004-04-22 | Francois Binette | Biocompatible scaffolds with tissue fragments |
| EP2070557A1 (fr) * | 2007-12-12 | 2009-06-17 | Xylos Corporation | Matériaux implantables à base de cellulose microbienne pour la réparation et la régénération de tissus durs |
| US20100159046A1 (en) * | 2008-12-19 | 2010-06-24 | Xylos Corporation | Minimal tissue attachment implantable materials |
| US20100297239A1 (en) * | 2008-12-22 | 2010-11-25 | Paul Gatenholm | Osseointegrative meniscus and cartilage implants based on beta-glucan nanocomposites |
| DE102009032216B4 (de) * | 2009-07-06 | 2019-06-06 | Aesculap Aktiengesellschaft | Spacer-Implantat zur Behandlung von menschlichen oder tierischen Gelenkknorpelschäden |
-
2011
- 2011-06-10 BR BRPI1102869-6A patent/BRPI1102869A2/pt not_active Application Discontinuation
-
2012
- 2012-06-06 WO PCT/BR2012/000179 patent/WO2012167341A1/fr not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116492518A (zh) * | 2023-05-12 | 2023-07-28 | 四川大学 | 一种功能等级双层膜及其制备方法与应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012167341A1 (fr) | 2012-12-13 |
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| Date | Code | Title | Description |
|---|---|---|---|
| B03A | Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07B | Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |