CA1006093A - Inhibition of leukemia utilizing 5-methyltetrahydrohomofolate - Google Patents

Inhibition of leukemia utilizing 5-methyltetrahydrohomofolate

Info

Publication number: CA1006093A
Authority: CA; Canada
Prior art keywords: methyltetrahydrohomofolate; leukemia; inhibition; utilizing; leukemia utilizing
Prior art date: 1972-07-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA175,097A

Other languages

English (en)

Other versions

CA175097S (en

Inventor

John A.R. Mead

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

UNITED STATES (GOVERNMENT OF THE) OF AMERICA AS REPRESENTED BY SECRE TARY DEPARTMENT OF HEALTH EDUCATION AND WELFARE

Original Assignee

UNITED STATES (GOVERNMENT OF THE) OF AMERICA AS REPRESENTED BY SECRE TARY DEPARTMENT OF HEALTH EDUCATION AND WELFARE

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-07-24

Filing date

1973-06-27

Publication date

1977-03-01

1973-06-27 Application filed by UNITED STATES (GOVERNMENT OF THE) OF AMERICA AS REPRESENTED BY SECRE TARY DEPARTMENT OF HEALTH EDUCATION AND WELFARE filed Critical UNITED STATES (GOVERNMENT OF THE) OF AMERICA AS REPRESENTED BY SECRE TARY DEPARTMENT OF HEALTH EDUCATION AND WELFARE

1977-03-01 Application granted granted Critical

1977-03-01 Publication of CA1006093A publication Critical patent/CA1006093A/en

Status Expired legal-status Critical Current

Links

230000005764 inhibitory process Effects 0.000 title 1
208000032839 leukemia Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CA175,097A 1972-07-24 1973-06-27 Inhibition of leukemia utilizing 5-methyltetrahydrohomofolate Expired CA1006093A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US00274749A US3856959A (en)	1972-07-24	1972-07-24	Inhibition of leukemia utilizing 5-methyltetrahydrohomofolate

Publications (1)

Publication Number	Publication Date
CA1006093A true CA1006093A (en)	1977-03-01

Family

ID=23049461

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA175,097A Expired CA1006093A (en)	1972-07-24	1973-06-27	Inhibition of leukemia utilizing 5-methyltetrahydrohomofolate

Country Status (11)

Country	Link
US (1)	US3856959A (de)
JP (1)	JPS5541207B2 (de)
AT (1)	AT329312B (de)
AU (1)	AU476551B2 (de)
BE (1)	BE802709A (de)
CA (1)	CA1006093A (de)
DE (1)	DE2335898A1 (de)
FR (1)	FR2193608B1 (de)
GB (1)	GB1442772A (de)
NL (1)	NL7309977A (de)
SE (1)	SE431612B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1572137A (en) *	1977-02-22	1980-07-23	Bioresearch Sas Del Dr Livio C	Stable compositions for therapeutic use based on d,1-5-methyltetrahydrofolic acid and its salts
US4684653A (en) *	1985-03-08	1987-08-04	The Trustees Of Princeton University	Pyrido(2,3-d)pyrimidine derivatives
US4927828A (en) *	1985-03-08	1990-05-22	The Trustees Of Princeton University	Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives
US5026851A (en) *	1985-03-08	1991-06-25	The Trustees Of Princeton University	Pyrido[2,3-]pyrimidine derivatives
US4833145A (en) *	1986-06-30	1989-05-23	The Trustees Of Princeton University	4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives
US4818819A (en) *	1986-10-20	1989-04-04	The Trustees Of Princeton University	Process for the preparation of fused pyridine compounds
US4902796A (en) *	1986-10-20	1990-02-20	The Trustees Of Princeton University	6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines
US5028608A (en) *	1989-12-11	1991-07-02	The Trustees Of Princeton University	N-(6-Amino-(pyrrolo(2,3-d)pyrimidin-3-ylacyl) )-glutamic acid derivatives
US9265746B2 (en) *	2006-05-31	2016-02-23	Merck & Cie	Method for cell-specific targeting

1972
- 1972-07-24 US US00274749A patent/US3856959A/en not_active Expired - Lifetime
1973
- 1973-06-27 CA CA175,097A patent/CA1006093A/en not_active Expired
- 1973-07-06 AU AU57820/73A patent/AU476551B2/en not_active Expired
- 1973-07-09 GB GB3252873A patent/GB1442772A/en not_active Expired
- 1973-07-14 DE DE19732335898 patent/DE2335898A1/de not_active Withdrawn
- 1973-07-18 NL NL7309977A patent/NL7309977A/xx not_active Application Discontinuation
- 1973-07-18 AT AT633073A patent/AT329312B/de not_active IP Right Cessation
- 1973-07-23 SE SE7310220A patent/SE431612B/xx unknown
- 1973-07-23 FR FR7326846A patent/FR2193608B1/fr not_active Expired
- 1973-07-24 JP JP8276773A patent/JPS5541207B2/ja not_active Expired
- 1973-07-24 BE BE133796A patent/BE802709A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
BE802709A (fr)	1973-11-16
JPS4950113A (de)	1974-05-15
AU476551B2 (en)	1976-09-30
DE2335898A1 (de)	1974-02-07
ATA633073A (de)	1975-07-15
US3856959A (en)	1974-12-24
FR2193608B1 (de)	1976-08-13
JPS5541207B2 (de)	1980-10-22
AT329312B (de)	1976-05-10
NL7309977A (de)	1974-01-28
SE431612B (sv)	1984-02-20
AU5782073A (en)	1975-01-09
GB1442772A (en)	1976-07-14
FR2193608A1 (de)	1974-02-22

Publication	Publication Date	Title
AU483098B2 (en)	1975-05-01	Showerhead
AU470375B2 (en)	1976-03-11	Substituted w-pentanorprostaglandins
AU476551B2 (en)	1976-09-30	Inhibition of leukemia utilizing 5-methyltetra-hydrohomofolate
CA980352A (en)	1975-12-23	Substituted aminohalopyridines
AU474093B2 (en)	1976-07-15	Chemosterilization of ixodides
CA1029734A (en)	1978-04-18	Manufacture of benzil-monoketals
CA1003646A (en)	1977-01-18	Evaporation of metals
AU472956B2 (en)	1976-06-10	Substituted benzodioxoles
AU5624873A (en)	1974-12-05	Metal-coil lacquers
CA991638A (en)	1976-06-22	Substituted 3-cyanobenzenesulfonamides
AU458647B2 (en)	1975-03-06	Manufacture of 6-60methylenetetracyclines
AU455096B2 (en)	1973-07-12	Manufacture of chlorofluoropyridines
AU471181B2 (en)	1976-04-08	Manufacture of bipridyls
AU463195B2 (en)	1975-07-17	Manufacture of &-6-deoxytetracyclines
AU489465B2 (en)	1975-02-13	Chemotherapeutic compositions
AU439138B2 (en)	1973-08-09	Substituted 10-aminoalkyl- or 10-bromoalkyl-anthracenes
CA995680A (en)	1976-08-24	Substituted 2-benzoyloxazolidines
CA915705A (en)	1972-11-28	Derivatives of dipropylacetylanilide
CA892026A (en)	1972-02-01	Derivatives of dibenzocycloheptenes
CA904356A (en)	1972-07-04	Synthesis of alkadienols
CA891405A (en)	1972-01-25	Decomposition inhibition
CA915708A (en)	1972-11-28	Manufacture of 2-ethylhexanal-1
CA1021790A (en)	1977-11-29	3-substituted-iodo-alkenyl compound
CA1006422A (en)	1977-03-08	Coating of metals
CA1033650A (en)	1978-06-27	Coating of metals