CA1022546A - P-glu-d-phe-trp-ser-tyr-d-ala-leu-arg-pro-gly-nh2 p-glu-d-phe-trp-ser-tyr-d-leu-leu-arg-pro-gly-nh2 et composes intermediaires - Google Patents

P-glu-d-phe-trp-ser-tyr-d-ala-leu-arg-pro-gly-nh2 p-glu-d-phe-trp-ser-tyr-d-leu-leu-arg-pro-gly-nh2 et composes intermediaires

Info

Publication number: CA1022546A
Authority: CA; Canada
Prior art keywords: leu; tyr; trp; glu; phe
Prior art date: 1973-10-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA209,974A

Other languages

English (en)

Other versions

CA209974S (en

Inventor

Theodore J. Foell

John P. Yardley

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wyeth LLC

Original Assignee

American Home Products Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-10-03

Filing date

1974-09-23

Publication date

1977-12-13

1973-10-03 Priority claimed from US00402958A external-priority patent/US3855199A/en

1973-11-21 Priority claimed from US417983A external-priority patent/US3886137A/en

1974-09-23 Application filed by American Home Products Corp filed Critical American Home Products Corp

1977-12-13 Application granted granted Critical

1977-12-13 Publication of CA1022546A publication Critical patent/CA1022546A/fr

Status Expired legal-status Critical Current

Links

VQKMKQJDJGQSDZ-SZYFUYGVSA-N (2s)-n-[(2r)-1-[[(2s)-1-[[(2s)-1-[[(2s)-1-[[(2r)-1-[[(2s)-1-[[(2s)-1-[(2s)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1 Chemical compound C([C@@H](C(=O)N[C@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](CC=1C=CC=CC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 VQKMKQJDJGQSDZ-SZYFUYGVSA-N 0.000 title 1
239000000543 intermediate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CA209,974A 1973-10-03 1974-09-23 P-glu-d-phe-trp-ser-tyr-d-ala-leu-arg-pro-gly-nh2 p-glu-d-phe-trp-ser-tyr-d-leu-leu-arg-pro-gly-nh2 et composes intermediaires Expired CA1022546A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US00402958A US3855199A (en)	1973-10-03	1973-10-03	P-glu-d-phe-t rp-ser-tyr-d-ala-leu-arg-pro-gly-nh2-and intermediates
US417983A US3886137A (en)	1973-11-21	1973-11-21	P-Glu-D-Phe-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-Gly-NH{HD 2 {B and intermediates

Publications (1)

Publication Number	Publication Date
CA1022546A true CA1022546A (fr)	1977-12-13

Family

ID=27018102

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA209,974A Expired CA1022546A (fr)	1973-10-03	1974-09-23	P-glu-d-phe-trp-ser-tyr-d-ala-leu-arg-pro-gly-nh2 p-glu-d-phe-trp-ser-tyr-d-leu-leu-arg-pro-gly-nh2 et composes intermediaires

Country Status (10)

Country	Link
JP (1)	JPS5059367A (fr)
CA (1)	CA1022546A (fr)
CH (1)	CH605676A5 (fr)
DE (1)	DE2447097A1 (fr)
FR (1)	FR2247254B1 (fr)
GB (1)	GB1458685A (fr)
IE (1)	IE40930B1 (fr)
NL (1)	NL7413081A (fr)
NZ (1)	NZ175566A (fr)
PH (1)	PH11571A (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4409208A (en) *	1980-04-15	1983-10-11	The Salk Institute For Biological Studies	GnRH antagonists
DE3842010A1 (de) *	1988-12-14	1990-06-21	Hoechst Ag	Kompetitive gonadoliberin-antagonisten

1974
- 1974-09-20 PH PH16314A patent/PH11571A/en unknown
- 1974-09-23 CA CA209,974A patent/CA1022546A/fr not_active Expired
- 1974-09-25 GB GB4161274A patent/GB1458685A/en not_active Expired
- 1974-10-01 IE IE2036/74A patent/IE40930B1/xx unknown
- 1974-10-01 NZ NZ175566A patent/NZ175566A/xx unknown
- 1974-10-02 FR FR7433242A patent/FR2247254B1/fr not_active Expired
- 1974-10-02 CH CH1327474A patent/CH605676A5/xx not_active IP Right Cessation
- 1974-10-02 DE DE19742447097 patent/DE2447097A1/de not_active Withdrawn
- 1974-10-02 JP JP49114274A patent/JPS5059367A/ja active Pending
- 1974-10-03 NL NL7413081A patent/NL7413081A/xx not_active Application Discontinuation

Also Published As

Publication number	Publication date
PH11571A (en)	1978-03-31
FR2247254B1 (fr)	1980-01-11
CH605676A5 (fr)	1978-10-13
AU7352074A (en)	1976-03-25
NZ175566A (en)	1978-06-20
FR2247254A1 (fr)	1975-05-09
JPS5059367A (fr)	1975-05-22
NL7413081A (nl)	1975-04-07
GB1458685A (en)	1976-12-15
DE2447097A1 (de)	1975-04-10
IE40930L (en)	1975-04-03
IE40930B1 (en)	1979-09-12

Publication	Publication Date	Title
AU474137B2 (en)	1976-07-15	Auto-refractometer
AU468964B2 (en)	1976-01-29	Melik
AU498889B2 (en)	1979-03-29	Piperidylene benzocycloheptathiophenes
CA994351A (en)	1976-08-03	Tetrahydronaphthyloxy-amines and related compounds
AU476397B2 (en)	1976-09-16	A-cycloalkylbenzyl lactamimides
AU476505B2 (en)	1976-09-23	Alkylbenxyl lactamimides
AU472907B2 (en)	1976-06-10	Firecheck
CA1022546A (fr)	1977-12-13	P-glu-d-phe-trp-ser-tyr-d-ala-leu-arg-pro-gly-nh2 p-glu-d-phe-trp-ser-tyr-d-leu-leu-arg-pro-gly-nh2 et composes intermediaires
AU470357B2 (en)	1976-03-11	p-HYDROXYMETHYLPHENYL-ACETAMIDICEPHALOSPORINS AND INTERMEDIATES
AU473700B2 (en)	1976-07-01	New thiadiazolylimidazolidinones
AU476386B2 (en)	1976-09-16	Dibenzocycloheptenyl lactamimides
AU471241B2 (en)	1976-04-15	Benzothiazolylureas
AU484357B2 (en)	1975-10-02	Oxathiolanes and oxathianes
AU6742774A (en)	1975-10-02	Oxathiolanes and oxathianes
AU471581B2 (en)	1976-04-29	New 16-hydroxy-17-aminosteroids
CA999112A (en)	1976-11-02	Brush hair-curler and brush-stand
AU489560B2 (en)	1976-01-15	Amidinoureas
AU486644B2 (en)	1975-12-18	Fusebox
AU479426B2 (en)	1975-08-21	Carbothiolates
AU481998B2 (en)	1975-11-06	Benzenedisulfonamides
AU482276B2 (en)	1976-04-08	Spiro-cyclopropanes
AU482530B2 (en)	1974-07-25	Benzocycloheptathiophenes
AU482866B2 (en)		Unsymmetrically-substituted-s-triazines
AU484993B2 (en)	1975-07-17	Polyhydroxyphenylchromanones
AU490583B2 (en)		4-aryl-5-aminoalkyl-4-oxazolin-2-ones