CA1033665A - Procede de preparation de liquides a application biologique et transporteurs d'oxygene - Google Patents

Procede de preparation de liquides a application biologique et transporteurs d'oxygene

Info

Publication number
CA1033665A
CA1033665A CA210,269A CA210269A CA1033665A CA 1033665 A CA1033665 A CA 1033665A CA 210269 A CA210269 A CA 210269A CA 1033665 A CA1033665 A CA 1033665A
Authority
CA
Canada
Prior art keywords
des
dans
est
émulsions
préparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA210,269A
Other languages
English (en)
Other versions
CA210269S (en
Inventor
Pierre Chabert
Louis Foulletier
Andre Lantz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Produits Chimiques Ugine Kuhlmann
Original Assignee
Produits Chimiques Ugine Kuhlmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Produits Chimiques Ugine Kuhlmann filed Critical Produits Chimiques Ugine Kuhlmann
Application granted granted Critical
Publication of CA1033665A publication Critical patent/CA1033665A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Colloid Chemistry (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

PRECIS DE LA DIVULGATION
Procédé de préparation d'émulsions de composes fluorés dans l'eau ou dans des solutions salines, pouvant être utilisées comme liquides biologiques transporteurs d'oxygène, consistant à émulsionner le composé fluoré en présence de deux émulsionnants dont l'un est à caractère hydrophile et l'autre à caractère lipophile. Ces émulsionnants sont des produits fluorés.
CA210,269A 1973-11-07 1974-09-27 Procede de preparation de liquides a application biologique et transporteurs d'oxygene Expired CA1033665A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7339533A FR2249657B1 (fr) 1973-11-07 1973-11-07

Publications (1)

Publication Number Publication Date
CA1033665A true CA1033665A (fr) 1978-06-27

Family

ID=9127407

Family Applications (1)

Application Number Title Priority Date Filing Date
CA210,269A Expired CA1033665A (fr) 1973-11-07 1974-09-27 Procede de preparation de liquides a application biologique et transporteurs d'oxygene

Country Status (11)

Country Link
US (1) US3989843A (fr)
JP (1) JPS5322140B2 (fr)
BE (1) BE821592A (fr)
CA (1) CA1033665A (fr)
CH (1) CH593692A5 (fr)
DE (1) DE2452513C3 (fr)
ES (1) ES431706A1 (fr)
FR (1) FR2249657B1 (fr)
GB (1) GB1459824A (fr)
IT (1) IT1050477B (fr)
NL (1) NL179786C (fr)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110474A (en) * 1977-08-26 1978-08-29 Suntech, Inc. Tetramethylpentane blood substitutes
US4183962A (en) * 1978-01-16 1980-01-15 Exxon Research & Engineering Co. Process for oxygenating blood by the utilization of liquid membranes
US4289499A (en) * 1978-10-13 1981-09-15 Childrens Hospital Medical Center Selecting perfluorocarbon compounds for synthetic blood
US4393863A (en) * 1980-04-14 1983-07-19 Thomas Jefferson University Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4657532A (en) * 1985-07-19 1987-04-14 Thomas Jefferson University Intra-peritoneal perfusion of oxygenated fluorocarbon
US4445514A (en) * 1980-04-14 1984-05-01 Thomas Jefferson University Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4445500A (en) * 1982-03-03 1984-05-01 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4795423A (en) * 1980-04-14 1989-01-03 Thomas Jefferson University Oxygenated perfluorinated perfusion of the ocular globe to treat ischemic retinopathy
US4758431A (en) * 1980-04-14 1988-07-19 Thomas Jefferson University Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4830849A (en) * 1980-04-14 1989-05-16 Thomas Jefferson University Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4445886A (en) * 1980-04-14 1984-05-01 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4840617A (en) * 1980-04-14 1989-06-20 Thomas Jefferson University Cerebral and lumbar perfusion catheterization apparatus for use in treating hypoxic/ischemic neurologic tissue
US4686085A (en) * 1980-04-14 1987-08-11 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4378797A (en) * 1980-04-14 1983-04-05 Thomas Jefferson University Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
JPS56166637U (fr) * 1980-05-14 1981-12-10
CA1181011A (fr) * 1980-05-27 1985-01-15 Robert P. Geyer N,n-dimethyl-cyclohexylmethylamine perfluoree et emulsions qui en renferment
US4369127A (en) * 1980-07-21 1983-01-18 Instrumentation Laboratory Inc. Blood gas control
FR2492814A1 (fr) * 1980-10-24 1982-04-30 Centre Nat Rech Scient Procede pour la synthese de composes hydrogenes et/ou fluores du type polyoxyethylene alkyl-ether, composes de ce type et application a titre d'agents tensio-actifs non ioniques
US4448188A (en) * 1982-02-18 1984-05-15 Laserscope, Inc. Method for providing an oxygen bearing liquid to a blood vessel for the performance of a medical procedure
US4450841A (en) * 1982-03-03 1984-05-29 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4446154A (en) * 1982-03-03 1984-05-01 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4446155A (en) * 1982-03-03 1984-05-01 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4451251A (en) * 1982-03-03 1984-05-29 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4445887A (en) * 1982-03-03 1984-05-01 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4445888A (en) * 1982-03-03 1984-05-01 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
FR2523956A1 (fr) * 1982-03-26 1983-09-30 Ugine Kuhlmann Bis-(perfluoroalkyl)-1,2-ethenes ramifies, leur preparation et leur utilisation comme transporteurs d'oxygene convertisseur electromecanique
US4397870A (en) * 1982-07-27 1983-08-09 The University Of Pennsylvania Process for prolonging retention of emulsion particles in the bloodstream
US4536323A (en) * 1983-06-28 1985-08-20 The Drackett Company Non-flammable aerosol propellant microemulsion system
US4655959A (en) * 1983-06-28 1987-04-07 The Drackett Company Preparation of non-flammable aerosol propellant microemulsion system
IT1183530B (it) * 1985-03-29 1987-10-22 Monteluos S P A Composizioni per cosmesi comprendente perfluoropolieteri
US5684050A (en) * 1986-01-24 1997-11-04 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5514720A (en) * 1986-07-09 1996-05-07 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5185099A (en) * 1988-04-20 1993-02-09 Institut National De Recherche Chimique Appliquee Visco-elastic, isotropic materials based on water, fluorinate sufactants and fluorinated oils, process for their preparation, and their use in various fields, such as optics, pharmacology and electrodynamics
FR2630347B1 (fr) * 1988-04-20 1991-08-30 Inst Nat Rech Chimique Materiaux viscoelastiques isotropes a base d'eau, de tensioactifs fluores et d'huiles fluorees, leur procede d'obtention et leurs applications dans divers domaines, tels que ceux de l'optique, de la pharmacologie et de l'electrodynamique
US5171755A (en) * 1988-04-29 1992-12-15 Hemagen/Pfc Emulsions of highly fluorinated organic compounds
US4975468A (en) * 1989-04-03 1990-12-04 Affinity Biotech, Inc. Fluorinated microemulsion as oxygen carrier
US5518731A (en) * 1990-09-27 1996-05-21 Allergan, Inc. Nonaqueous fluorinated drug delivery vehicle suspensions
US6458376B1 (en) 1990-09-27 2002-10-01 Allergan, Inc. Nonaqueous fluorinated drug delivery suspensions
FR2679150A1 (fr) * 1991-07-17 1993-01-22 Atta Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations.
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
US5403575A (en) * 1991-12-12 1995-04-04 Hemagen/Pfc Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them
US5846516A (en) * 1992-06-03 1998-12-08 Alliance Pharmaceutial Corp. Perfluoroalkylated amphiphilic phosphorus compounds: preparation and biomedical applications
US5595687A (en) * 1992-10-30 1997-01-21 Thomas Jefferson University Emulsion stability
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Phase shift colloids as ultrasound contrast agents
FR2700696B1 (fr) * 1993-01-28 1995-04-07 Atta Dispersions, émulsions, microémulsions, gels et compositions à usage biomédical comprenant un composé organique fluoré iodé, utilisables notamment comme agent de contraste.
WO1994019101A1 (fr) * 1993-02-16 1994-09-01 Alliance Pharmaceutical Corp. Procede de microemulsification d'huiles fluorees
US5480914A (en) * 1994-05-06 1996-01-02 Allergan, Inc. Nonaqueous thixotropic drug delivery suspensions and methods of their use
US5567857A (en) * 1994-06-21 1996-10-22 E. I. Du Pont De Nemours And Company Fluoroalkylethoxylate compositions having enhanced water solubility
CA2309170A1 (fr) * 1997-11-13 1999-05-27 Mark W. Grenfell Procedes d'usinage de metal et compositions afferentes utiles en tant que fluides d'usinage
US6864386B1 (en) * 2001-11-21 2005-03-08 Sonus Pharmaceuticals, Inc. Fluorinated compounds
WO2015164781A1 (fr) * 2014-04-25 2015-10-29 Wisconsin Alumni Research Foundation Émulsions de fluoropolymères comportant des copolymères séquencés semi-fluorés et ramifiés ou un tensioactif phospholipidique pour l'administration de médicaments hydrophobes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1252728A (fr) * 1970-04-23 1971-11-10

Also Published As

Publication number Publication date
DE2452513A1 (de) 1975-05-28
BE821592A (fr) 1975-02-17
FR2249657B1 (fr) 1977-04-15
NL179786B (nl) 1986-06-16
IT1050477B (it) 1981-03-10
AU7505274A (en) 1976-05-06
CH593692A5 (fr) 1977-12-15
GB1459824A (en) 1976-12-31
DE2452513C3 (de) 1980-11-20
FR2249657A1 (fr) 1975-05-30
JPS5082225A (fr) 1975-07-03
NL7414479A (nl) 1975-05-12
DE2452513B2 (de) 1976-08-19
JPS5322140B2 (fr) 1978-07-06
ES431706A1 (es) 1976-11-16
NL179786C (nl) 1986-11-17
US3989843A (en) 1976-11-02

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