CA1034941A - N-nitroso compounds, compositions containing such compounds, processes for their preparation and methods of treatment therewith, and novel intermediates - Google Patents

N-nitroso compounds, compositions containing such compounds, processes for their preparation and methods of treatment therewith, and novel intermediates

Info

Publication number
CA1034941A
CA1034941A CA193,912A CA193912A CA1034941A CA 1034941 A CA1034941 A CA 1034941A CA 193912 A CA193912 A CA 193912A CA 1034941 A CA1034941 A CA 1034941A
Authority
CA
Canada
Prior art keywords
compounds
processes
preparation
methods
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA193,912A
Other languages
English (en)
French (fr)
Other versions
CA193912S (en
Inventor
Knut B. Hogberg
Hans J. Fex
Imre Konyves
Anders R. Stamvik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo AB
Original Assignee
Leo AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo AB filed Critical Leo AB
Application granted granted Critical
Publication of CA1034941A publication Critical patent/CA1034941A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA193,912A 1973-03-05 1974-03-04 N-nitroso compounds, compositions containing such compounds, processes for their preparation and methods of treatment therewith, and novel intermediates Expired CA1034941A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1061373A GB1458372A (en) 1973-03-05 1973-03-05 Steroid carbamates and allophanates

Publications (1)

Publication Number Publication Date
CA1034941A true CA1034941A (en) 1978-07-18

Family

ID=9971097

Family Applications (1)

Application Number Title Priority Date Filing Date
CA193,912A Expired CA1034941A (en) 1973-03-05 1974-03-04 N-nitroso compounds, compositions containing such compounds, processes for their preparation and methods of treatment therewith, and novel intermediates

Country Status (18)

Country Link
US (1) US3963707A (de)
JP (1) JPS5613720B2 (de)
AT (1) AT343293B (de)
BE (1) BE811775A (de)
CA (1) CA1034941A (de)
CH (1) CH606109A5 (de)
DE (1) DE2409436A1 (de)
DK (1) DK134915B (de)
ES (1) ES423694A1 (de)
FI (1) FI53578C (de)
FR (1) FR2220261B1 (de)
GB (1) GB1458372A (de)
HU (1) HU168811B (de)
IE (1) IE38909B1 (de)
NL (1) NL7402961A (de)
NO (1) NO740747L (de)
SE (1) SE401513B (de)
SU (1) SU512714A3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523035A (en) * 1976-03-10 1978-08-31 Leo Ab Derivatives of estradiol - 17 - dihydrogen phosphates
US4261910A (en) * 1978-08-14 1981-04-14 Kureha Kagaku Kogyo Kabushiki Kaisha Process for the preparation of Chlorambucil derivatives
DE3210637A1 (de) * 1982-03-23 1983-09-29 Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg Steroidester von n-(2-halogenethyl)-n-nitroso-carbamoylaminosaeuren und deren peptiden, sowie verfahren zu deren herstellung
JPS61293993A (ja) * 1985-06-21 1986-12-24 Kureha Chem Ind Co Ltd 新規な螢光物質,その製造方法及び薬剤
US5792758A (en) * 1995-12-08 1998-08-11 G. D. Searle & Co. Steroid nitrite ester derivatives useful as anti-inflammatory drugs
US5912240A (en) * 1997-04-10 1999-06-15 Loria; Roger M. 5-androstene 3β, 17α diol as an inhibitor of tumor growth
IT1311922B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.

Also Published As

Publication number Publication date
JPS5613720B2 (de) 1981-03-30
ES423694A1 (es) 1976-04-16
JPS5029549A (de) 1975-03-25
AT343293B (de) 1978-05-26
ATA181074A (de) 1977-09-15
GB1458372A (en) 1976-12-15
SE401513B (sv) 1978-05-16
NL7402961A (de) 1974-09-09
DK134915C (de) 1977-06-27
NO740747L (no) 1974-09-06
BE811775A (fr) 1974-07-01
FR2220261A1 (de) 1974-10-04
SU512714A3 (ru) 1976-04-30
IE38909B1 (en) 1978-06-21
FR2220261B1 (de) 1978-02-03
DE2409436A1 (de) 1974-09-12
FI53578C (fi) 1978-06-12
HU168811B (de) 1976-07-28
US3963707A (en) 1976-06-15
FI53578B (de) 1978-02-28
CH606109A5 (de) 1978-10-13
DK134915B (da) 1977-02-07
IE38909L (en) 1974-09-05

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