CA1049934A - Dialyseur avec dispositif de filtration du dialysat - Google Patents

Dialyseur avec dispositif de filtration du dialysat

Info

Publication number: CA1049934A
Authority: CA; Canada
Prior art keywords: dialysate; efflux; toxic; membranes; dialysis
Prior art date: 1973-12-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA189,242A

Other languages

English (en)

Inventor

Clinton E. Brown

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

HYDRONAUTICS

Original Assignee

HYDRONAUTICS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-12-31

Filing date

1973-12-31

Publication date

1979-03-06

1973-12-31 Application filed by HYDRONAUTICS filed Critical HYDRONAUTICS

1973-12-31 Priority to CA189,242A priority Critical patent/CA1049934A/fr

1974-06-07 Priority to CA201,885A priority patent/CA1038776A/fr

1979-03-06 Application granted granted Critical

1979-03-06 Publication of CA1049934A publication Critical patent/CA1049934A/fr

Status Expired legal-status Critical Current

Links

238000000746 purification Methods 0.000 title claims description 12
239000008280 blood Substances 0.000 claims abstract description 65
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239000003792 electrolyte Substances 0.000 claims abstract description 52
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231100000331 toxic Toxicity 0.000 claims abstract description 29
230000002588 toxic effect Effects 0.000 claims abstract description 29
210000003734 kidney Anatomy 0.000 claims abstract description 28
239000000706 filtrate Substances 0.000 claims abstract description 27
238000001914 filtration Methods 0.000 claims abstract description 25
210000001124 body fluid Anatomy 0.000 claims abstract description 12
231100000614 poison Toxicity 0.000 claims abstract description 12
239000003440 toxic substance Substances 0.000 claims abstract description 12
239000008151 electrolyte solution Substances 0.000 claims abstract description 8
238000009792 diffusion process Methods 0.000 claims abstract description 7
210000004379 membrane Anatomy 0.000 claims description 67
239000012528 membrane Substances 0.000 claims description 67
238000000502 dialysis Methods 0.000 claims description 30
238000000909 electrodialysis Methods 0.000 claims description 14
239000000463 material Substances 0.000 claims description 14
239000012530 fluid Substances 0.000 claims description 11
239000010839 body fluid Substances 0.000 claims description 10
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238000001631 haemodialysis Methods 0.000 claims description 10
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230000003204 osmotic effect Effects 0.000 claims description 9
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XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 12
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239000004202 carbamide Substances 0.000 description 8
DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 8
LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 6
238000010276 construction Methods 0.000 description 6
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TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 5
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ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 4
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206010053567 Coagulopathies Diseases 0.000 description 2
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HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
239000004677 Nylon Substances 0.000 description 2
208000036366 Sensation of pressure Diseases 0.000 description 2
UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 2
230000009471 action Effects 0.000 description 2
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
210000004027 cell Anatomy 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
230000035602 clotting Effects 0.000 description 2
CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
239000011521 glass Substances 0.000 description 2
229960002897 heparin Drugs 0.000 description 2
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230000001965 increasing effect Effects 0.000 description 2
150000002500 ions Chemical class 0.000 description 2
238000011068 loading method Methods 0.000 description 2
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210000004303 peritoneum Anatomy 0.000 description 2
239000000600 sorbitol Substances 0.000 description 2
235000000346 sugar Nutrition 0.000 description 2
150000008163 sugars Chemical class 0.000 description 2
210000005239 tubule Anatomy 0.000 description 2
HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
241001631457 Cannula Species 0.000 description 1
229920000298 Cellophane Polymers 0.000 description 1
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
206010014418 Electrolyte imbalance Diseases 0.000 description 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
229910019142 PO4 Inorganic materials 0.000 description 1
JDDHUROHDHPVIO-UHFFFAOYSA-N Piperazine citrate Chemical compound C1CNCCN1.C1CNCCN1.C1CNCCN1.OC(=O)CC(O)(C(O)=O)CC(O)=O.OC(=O)CC(O)(C(O)=O)CC(O)=O JDDHUROHDHPVIO-UHFFFAOYSA-N 0.000 description 1
239000004372 Polyvinyl alcohol Substances 0.000 description 1
NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 1
FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
239000004809 Teflon Substances 0.000 description 1
229920006362 Teflon® Polymers 0.000 description 1
229920006356 Teflon™ FEP Polymers 0.000 description 1
208000007536 Thrombosis Diseases 0.000 description 1
125000000129 anionic group Chemical group 0.000 description 1
239000003146 anticoagulant agent Substances 0.000 description 1
229940127219 anticoagulant drug Drugs 0.000 description 1
210000001367 artery Anatomy 0.000 description 1
230000000712 assembly Effects 0.000 description 1
238000000429 assembly Methods 0.000 description 1
210000000601 blood cell Anatomy 0.000 description 1
230000017531 blood circulation Effects 0.000 description 1
210000001772 blood platelet Anatomy 0.000 description 1
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238000005260 corrosion Methods 0.000 description 1
229940072645 coumadin Drugs 0.000 description 1
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239000008103 glucose Substances 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
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QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
230000000737 periodic effect Effects 0.000 description 1
239000012466 permeate Substances 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
239000010452 phosphate Substances 0.000 description 1
230000035479 physiological effects, processes and functions Effects 0.000 description 1
229920000647 polyepoxide Polymers 0.000 description 1
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229920001296 polysiloxane Polymers 0.000 description 1
229920002451 polyvinyl alcohol Polymers 0.000 description 1
BITYAPCSNKJESK-UHFFFAOYSA-N potassiosodium Chemical compound [Na].[K] BITYAPCSNKJESK-UHFFFAOYSA-N 0.000 description 1
229910001414 potassium ion Inorganic materials 0.000 description 1
238000004321 preservation Methods 0.000 description 1
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239000010935 stainless steel Substances 0.000 description 1
230000008093 supporting effect Effects 0.000 description 1
229910052715 tantalum Inorganic materials 0.000 description 1
GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
210000001519 tissue Anatomy 0.000 description 1
239000003053 toxin Substances 0.000 description 1
PJVWKTKQMONHTI-UHFFFAOYSA-N warfarin Chemical compound OC=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 PJVWKTKQMONHTI-UHFFFAOYSA-N 0.000 description 1

Landscapes

External Artificial Organs (AREA)

CA189,242A 1973-12-31 1973-12-31 Dialyseur avec dispositif de filtration du dialysat Expired CA1049934A (fr)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
CA189,242A CA1049934A (fr)	1973-12-31	1973-12-31	Dialyseur avec dispositif de filtration du dialysat
CA201,885A CA1038776A (fr)	1973-12-31	1974-06-07	Appareil de dialyse peritoneale avec filtration du dialysat

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CA189,242A CA1049934A (fr)	1973-12-31	1973-12-31	Dialyseur avec dispositif de filtration du dialysat

Publications (1)

Publication Number	Publication Date
CA1049934A true CA1049934A (fr)	1979-03-06

Family

ID=4098823

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CA189,242A Expired CA1049934A (fr)	1973-12-31	1973-12-31	Dialyseur avec dispositif de filtration du dialysat
CA201,885A Expired CA1038776A (fr)	1973-12-31	1974-06-07	Appareil de dialyse peritoneale avec filtration du dialysat

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CA201,885A Expired CA1038776A (fr)	1973-12-31	1974-06-07	Appareil de dialyse peritoneale avec filtration du dialysat

Country Status (1)

Country	Link
CA (2)	CA1049934A (fr)

1973
- 1973-12-31 CA CA189,242A patent/CA1049934A/fr not_active Expired
1974
- 1974-06-07 CA CA201,885A patent/CA1038776A/fr not_active Expired

Also Published As

Publication number	Publication date
CA1038776A (fr)	1978-09-19

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EP0980685B1 (fr)	2006-01-25	Utilisation d'un liquide pour la fabrication d'un liquide de dialyse pour la dialyse péritonéale continue avec recirculation
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Saito	2003	Development of bioartificial kidneys
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AU2012202882B2 (en)	2012-09-20	System and method for regeneration of a fluid
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DE7315909U (de)	1973-10-11	Vorrichtung zum abscheiden toxischer sabstanzen aus körperfluiden, insbesondere zur verwendung als künstliche niere
Lysaght et al.	1985	Mass transfer in arteriovenous hemofiltration