CA1050975A - DERIVES 2-HYDROXY-.omega.-AMINOALKYL D'ANTIBIOTIQUES DE TYPE AMINOGLYCOSIDE - Google Patents

DERIVES 2-HYDROXY-.omega.-AMINOALKYL D'ANTIBIOTIQUES DE TYPE AMINOGLYCOSIDE

Info

Publication number
CA1050975A
CA1050975A CA262,724A CA262724A CA1050975A CA 1050975 A CA1050975 A CA 1050975A CA 262724 A CA262724 A CA 262724A CA 1050975 A CA1050975 A CA 1050975A
Authority
CA
Canada
Prior art keywords
formula
group
hydrogen atom
amino
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA262,724A
Other languages
English (en)
Inventor
James W. Moore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ZA00756326A external-priority patent/ZA756326B/xx
Priority claimed from GB1542576A external-priority patent/GB1512475A/en
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Application granted granted Critical
Publication of CA1050975A publication Critical patent/CA1050975A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CA262,724A 1975-10-06 1976-10-05 DERIVES 2-HYDROXY-.omega.-AMINOALKYL D'ANTIBIOTIQUES DE TYPE AMINOGLYCOSIDE Expired CA1050975A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ZA00756326A ZA756326B (en) 1974-10-26 1975-10-06 2-hydroxy-aminoalkyl-derivatives of aminoglycoside antibiotics
NZ179050A NZ179050A (en) 1974-10-26 1975-10-24 Antibacterial 2-deoxystreptamine amino-glycosides (2-hydroxy-w-aminoalkyl derivatiues): and pharmaceutical compositions
GB1542576A GB1512475A (en) 1974-10-26 1976-04-15 Aminoglycosides

Publications (1)

Publication Number Publication Date
CA1050975A true CA1050975A (fr) 1979-03-20

Family

ID=27257257

Family Applications (1)

Application Number Title Priority Date Filing Date
CA262,724A Expired CA1050975A (fr) 1975-10-06 1976-10-05 DERIVES 2-HYDROXY-.omega.-AMINOALKYL D'ANTIBIOTIQUES DE TYPE AMINOGLYCOSIDE

Country Status (6)

Country Link
BG (1) BG25098A3 (fr)
CA (1) CA1050975A (fr)
FR (1) FR2326931A2 (fr)
HU (1) HU175520B (fr)
NL (1) NL160833C (fr)
PH (1) PH14200A (fr)

Also Published As

Publication number Publication date
PH14200A (en) 1981-03-31
BG25098A3 (en) 1978-07-12
NL7611021A (nl) 1977-04-12
HU175520B (hu) 1980-08-28
NL160833C (nl) 1979-12-17
FR2326931A2 (fr) 1977-05-06
AU1823576A (en) 1978-03-23
FR2326931B2 (fr) 1978-12-15

Similar Documents

Publication Publication Date Title
Wright Synthesis of 1-N-ethylsisomicin: a broad-spectrum semisynthetic aminoglycoside antibiotic
RU2604665C2 (ru) Лечение бактериальных инфекционных заболеваний
US4214074A (en) Hydroxyalkyl derivatives of aminoglycoside antibiotics
US4170642A (en) Derivatives of kanamycin A
US3784541A (en) Polyamine compounds and methods for their production
US4169141A (en) 1-Peptidyl derivatives of di-O-aminoglycosyl-1,3-diaminocyclitol antibacterial agents
US4104372A (en) 1-N-(α-hydroxy-ω-aminoalkanoyl) derivatives of 3'-deoxykanamycin A and the production thereof
CA1050975A (fr) DERIVES 2-HYDROXY-.omega.-AMINOALKYL D'ANTIBIOTIQUES DE TYPE AMINOGLYCOSIDE
US3981861A (en) Antibiotic aminoglycosides, processes of preparation and pharmaceutical compositions
CA1039275A (fr) Derives hydroxy-2 w-aminoalkyles d'aminoglycoside
US3652537A (en) Epierythromycylamine and epierythromycyl b amine
US4217446A (en) ωAmino-2-hydroxyalkyl derivatives of aminoglycoside antibiotics
US4031210A (en) Antibiotic aminoglycosides, processes of preparation and pharmaceutical compositions
KR790001305B1 (ko) 2-데옥시스트랲트아민아미노그리코시드류의제조방법
IE45029B1 (en) Aminoglycosides
US4140849A (en) Kanamycin C derivatives
US4170643A (en) Aminoglycoside-aminocyclitol derivatives and method of use
KR790001020B1 (ko) 항균물질인 2-데옥시 스트렙타민-아미노 배당체류의 제조방법
US4205070A (en) 6'N-Alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B
US4147861A (en) 1N-(α-Hydroxy-ω-aminoalkanoyl)-6'N-methyl-3',4'-dideoxykanamycin B and the production thereof
CS195713B2 (cs) Způsob výroby nových amfeoglykosidů 2-dsoxystreptaminu
CA1081693A (fr) Derives de la kanamycine c
IE49299B1 (en) Aminoglycoside derivatives of desoxystreptamine,processes for preparing them and pharmaceutical compositions containing them
GB2059957A (en) Fortimicin derivatives
GB1577540A (en) Derivatives of 4,6-di-o-(aminoglycosyl)-1,3-dimaniocyclitols