CA1085831A - Preparation of substituted w-pentanorprostaglandins - Google Patents

Preparation of substituted w-pentanorprostaglandins

Info

Publication number: CA1085831A
Authority: CA; Canada
Prior art keywords: formula; compound; double bond; trans; cooh
Prior art date: 1972-11-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA185,274A

Other languages

English (en)

French (fr)

Other versions

CA185274S (en

Inventor

Jasjit S. Bindra

Michael R. Johnson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Inc

Original Assignee

Pfizer Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-11-08

Filing date

1973-11-07

Publication date

1980-09-16

1973-11-07 Application filed by Pfizer Inc filed Critical Pfizer Inc

1980-09-16 Application granted granted Critical

1980-09-16 Publication of CA1085831A publication Critical patent/CA1085831A/en

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Furan Compounds (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

CA185,274A 1972-11-08 1973-11-07 Preparation of substituted w-pentanorprostaglandins Expired CA1085831A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US30481372A	1972-11-08	1972-11-08
US304,813		1972-11-08

Publications (1)

Publication Number	Publication Date
CA1085831A true CA1085831A (en)	1980-09-16

Family

ID=23178133

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
CA185,274A Expired CA1085831A (en)	1972-11-08	1973-11-07	Preparation of substituted w-pentanorprostaglandins
CA341,898A Expired CA1088931A (en)	1972-11-08	1977-07-11	Preparation of 9-oxo tetrahydropyranyl substituted prostaglandin intermediates
CA341,897A Expired CA1088930A (en)	1972-11-08	1977-07-11	Preparation of 9-hydroxy tetrahydropyranyl substituted prostaglandin intermediates

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
CA341,898A Expired CA1088931A (en)	1972-11-08	1977-07-11	Preparation of 9-oxo tetrahydropyranyl substituted prostaglandin intermediates
CA341,897A Expired CA1088930A (en)	1972-11-08	1977-07-11	Preparation of 9-hydroxy tetrahydropyranyl substituted prostaglandin intermediates

Country Status (29)

Country	Link
JP (3)	JPS5416491B2 (de)
AR (3)	AR200585A1 (de)
AT (3)	AT367034B (de)
AU (1)	AU470375B2 (de)
BE (1)	BE806995A (de)
CA (3)	CA1085831A (de)
CH (1)	CH597176A5 (de)
CS (3)	CS182791B2 (de)
DD (4)	DD118856A5 (de)
DE (1)	DE2355540C2 (de)
DK (1)	DK144247C (de)
ES (3)	ES420325A1 (de)
FI (1)	FI60389C (de)
FR (3)	FR2205335B1 (de)
GB (3)	GB1456512A (de)
HK (3)	HK28079A (de)
HU (3)	HU172703B (de)
IE (1)	IE39537B1 (de)
IL (1)	IL43589A (de)
IN (1)	IN139384B (de)
KE (3)	KE2930A (de)
MY (3)	MY7900246A (de)
NL (1)	NL164273C (de)
NO (3)	NO147836C (de)
PH (3)	PH13272A (de)
SE (4)	SE448992B (de)
SU (4)	SU584766A3 (de)
YU (3)	YU39715B (de)
ZA (1)	ZA738554B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3929862A (en) *	1974-01-08	1975-12-30	Upjohn Co	Substituted tolylesters of PGF{HD 2{B {60
US3986764A (en) *	1975-03-31	1976-10-19	Gte Automatic Electric Laboratories Incorporated	Panel for supporting a pair of elongated mating connectors and selectively locking them together
GB1506817A (en) *	1975-03-31	1978-04-12	Upjohn Co	Prostaglandins
ES449162A1 (es) *	1975-06-23	1977-12-16	Syntex Inc	Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.
GB1516414A (en) *	1975-08-22	1978-07-05	Ici Ltd	Prostane derivatives
SE7809008L (sv) *	1977-12-12	1979-06-13	Upjohn Co	Anvendning av amider av prostaglandintyp for att styra eller reglera reproduktionscykeln hos individer tillhorande deggdjursarter
IN150279B (de) *	1978-01-16	1982-09-04	Pfizer
SK3382000A3 (en) *	1997-09-09	2000-10-09	Procter & Gamble	A compound having structure of aromatic substituted prostaglandins and its use for the treatment of bone disorders
CA2364948C (en)	1999-03-05	2011-04-26	Duke University	C16 unsaturated fp-selective prostaglandins analogs
US6894175B1 (en)	1999-08-04	2005-05-17	The Procter & Gamble Company	2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020013294A1 (en)	2000-03-31	2002-01-31	Delong Mitchell Anthony	Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en)	2000-03-31	2002-11-21	Delong Michell Anthony	Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020037914A1 (en)	2000-03-31	2002-03-28	Delong Mitchell Anthony	Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
JP2002329615A (ja) *	2001-05-02	2002-11-15	Ohira Denshi Kk	トロイダルコイル
US6476064B1 (en) *	2001-06-13	2002-11-05	Allergan, Inc.	Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents
US20060135609A1 (en)	2004-10-21	2006-06-22	Duke University	Ophthamological drugs
US8722739B2 (en)	2008-10-29	2014-05-13	Novaer Holdings, Inc.	Amino acid salts of prostaglandins
US8623918B2 (en)	2008-10-29	2014-01-07	Novaer Holdings, Inc.	Amino acid salts of prostaglandins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1324737A (en) *	1970-11-02	1973-07-25	Upjohn Co	Prostaglandins and the preparation thereof
IE37602B1 (en) *	1971-05-11	1977-08-31	Ici Ltd	Cyclopentane derivatives

1972
- 1972-11-07 DD DD182498*A patent/DD118856A5/xx unknown
1973
- 1973-10-29 SE SE7314686A patent/SE448992B/xx unknown
- 1973-11-07 IL IL43589A patent/IL43589A/en unknown
- 1973-11-07 ES ES420325A patent/ES420325A1/es not_active Expired
- 1973-11-07 GB GB5175873A patent/GB1456512A/en not_active Expired
- 1973-11-07 GB GB2285876A patent/GB1456514A/en not_active Expired
- 1973-11-07 DD DD174504A patent/DD109212A5/xx unknown
- 1973-11-07 JP JP12527273A patent/JPS5416491B2/ja not_active Expired
- 1973-11-07 ZA ZA738554A patent/ZA738554B/xx unknown
- 1973-11-07 AT AT0936973A patent/AT367034B/de not_active IP Right Cessation
- 1973-11-07 IE IE2002/73A patent/IE39537B1/xx unknown
- 1973-11-07 DK DK601073A patent/DK144247C/da not_active IP Right Cessation
- 1973-11-07 DD DD182497*A patent/DD117233A5/xx unknown
- 1973-11-07 PH PH15191A patent/PH13272A/en unknown
- 1973-11-07 AR AR250885A patent/AR200585A1/es active
- 1973-11-07 BE BE1005485A patent/BE806995A/xx not_active IP Right Cessation
- 1973-11-07 IN IN2448/CAL/73A patent/IN139384B/en unknown
- 1973-11-07 CA CA185,274A patent/CA1085831A/en not_active Expired
- 1973-11-07 YU YU2880/73A patent/YU39715B/xx unknown
- 1973-11-07 NO NO4288/73A patent/NO147836C/no unknown
- 1973-11-07 GB GB2395076A patent/GB1456513A/en not_active Expired
- 1973-11-07 DE DE2355540A patent/DE2355540C2/de not_active Expired
- 1973-11-07 NL NL7315263.A patent/NL164273C/xx not_active IP Right Cessation
- 1973-11-07 AU AU62247/73A patent/AU470375B2/en not_active Expired
- 1973-11-07 DD DD182499*A patent/DD119411A5/xx unknown
- 1973-11-07 FI FI3443/73A patent/FI60389C/fi active
- 1973-11-07 CH CH1563973A patent/CH597176A5/xx not_active IP Right Cessation
- 1973-11-07 FR FR7339544A patent/FR2205335B1/fr not_active Expired
- 1973-11-08 HU HU72PI00000399A patent/HU172703B/hu unknown
- 1973-11-08 CS CS7300007669A patent/CS182791B2/cs unknown
- 1973-11-08 HU HU73PI00000452A patent/HU171819B/hu unknown
- 1973-11-08 CS CS7500006066A patent/CS182794B2/cs unknown
- 1973-11-08 CS CS7500006065A patent/CS182793B2/cs unknown
- 1973-11-08 HU HU73PI451A patent/HU173507B/hu unknown
- 1973-11-11 SU SU7301971722A patent/SU584766A3/ru active
1974
- 1974-06-06 AR AR254090A patent/AR202931A1/es active
- 1974-06-06 AR AR254091A patent/AR199966A1/es active
- 1974-09-26 NO NO743493A patent/NO148998C/no unknown
- 1974-12-18 ES ES433047A patent/ES433047A1/es not_active Expired
- 1974-12-18 ES ES433046A patent/ES433046A1/es not_active Expired
1975
- 1975-02-18 NO NO750535A patent/NO149139C/no unknown
- 1975-02-18 SU SU752106791A patent/SU667141A3/ru active
- 1975-02-19 SU SU752106125A patent/SU893130A3/ru active
- 1975-07-24 PH PH17410A patent/PH13110A/en unknown
- 1975-07-24 PH PH17409A patent/PH13325A/en unknown
- 1975-08-22 FR FR7526060A patent/FR2283146A1/fr active Granted
- 1975-08-22 FR FR7526059A patent/FR2279729A1/fr active Granted
1976
- 1976-07-23 AT AT544576A patent/AT360672B/de not_active IP Right Cessation
- 1976-07-23 AT AT544676A patent/AT353285B/de active
- 1976-10-15 JP JP51123737A patent/JPS5253841A/ja active Pending
- 1976-10-15 JP JP51123738A patent/JPS5257147A/ja active Pending
1977
- 1977-01-24 SE SE7700716A patent/SE445111B/xx not_active IP Right Cessation
- 1977-01-24 SE SE7700718A patent/SE431756B/xx not_active IP Right Cessation
- 1977-01-24 SE SE7700717A patent/SE436278B/xx not_active IP Right Cessation
- 1977-07-11 CA CA341,898A patent/CA1088931A/en not_active Expired
- 1977-07-11 CA CA341,897A patent/CA1088930A/en not_active Expired
1978
- 1978-07-27 SU SU782629453A patent/SU745362A3/ru active
1979
- 1979-03-15 KE KE2930A patent/KE2930A/xx unknown
- 1979-03-15 KE KE2931A patent/KE2931A/xx unknown
- 1979-03-15 KE KE2932A patent/KE2932A/xx unknown
- 1979-05-03 HK HK280/79A patent/HK28079A/xx unknown
- 1979-05-03 HK HK279/79A patent/HK27979A/xx unknown
- 1979-05-03 HK HK281/79A patent/HK28179A/xx unknown
- 1979-12-30 MY MY246/79A patent/MY7900246A/xx unknown
- 1979-12-30 MY MY245/79A patent/MY7900245A/xx unknown
- 1979-12-30 MY MY243/79A patent/MY7900243A/xx unknown
1980
- 1980-10-23 YU YU2706/80A patent/YU37316B/xx unknown
- 1980-10-23 YU YU2707/80A patent/YU36975B/xx unknown

Also Published As

Publication number	Publication date
CA1088930A (en)	1980-11-04
DE2355540A1 (de)	1974-05-22
YU270780A (en)	1982-06-18
YU39715B (en)	1985-04-30
NO148998B (no)	1983-10-17
CS182794B2 (en)	1978-05-31
IL43589A0 (en)	1974-03-14
FR2279729A1 (fr)	1976-02-20
KE2931A (en)	1979-03-30
AR200585A1 (es)	1974-11-22
FR2205335B1 (de)	1978-07-13
HU171819B (hu)	1978-03-28
HU172703B (hu)	1978-11-28
AT367034B (de)	1982-05-25
SE448992B (sv)	1987-03-30
PH13325A (en)	1980-03-13
GB1456514A (en)	1976-11-24
SE7700717L (sv)	1977-01-24
SU745362A3 (ru)	1980-06-30
KE2930A (en)	1979-03-30
PH13110A (en)	1979-11-28
SE445111B (sv)	1986-06-02
JPS5257147A (en)	1977-05-11
DK144247B (da)	1982-01-25
FR2283146A1 (fr)	1976-03-26
DE2365322B2 (de)	1977-02-24
MY7900245A (en)	1979-12-31
DD109212A5 (de)	1974-10-20
NO149139C (no)	1984-02-29
SU893130A3 (ru)	1981-12-23
ES433046A1 (es)	1977-06-16
AR199966A1 (es)	1974-10-08
SE431756B (sv)	1984-02-27
HK27979A (en)	1979-05-11
NL7315263A (de)	1974-05-10
YU36975B (en)	1984-08-31
NL164273C (nl)	1980-12-15
JPS5253841A (en)	1977-04-30
SE7700718L (sv)	1977-01-24
NO750535L (de)	1974-05-09
NO147836C (no)	1983-06-22
SU584766A3 (ru)	1977-12-15
FI60389C (fi)	1982-01-11
NO148998C (no)	1984-01-25
SE7700716L (sv)	1977-01-24
DE2355540C2 (de)	1982-11-18
AR202931A1 (es)	1975-07-31
DD118856A5 (de)	1976-03-20
IN139384B (de)	1976-06-12
AU470375B2 (en)	1976-03-11
NO743493L (no)	1974-05-09
YU37316B (en)	1984-08-31
DK144247C (da)	1982-07-12
SU667141A3 (ru)	1979-06-05
AT353285B (de)	1979-11-12
IE39537L (en)	1974-05-08
MY7900243A (en)	1979-12-31
ES433047A1 (es)	1976-11-01
AT360672B (de)	1981-01-26
GB1456512A (en)	1976-11-24
HK28179A (en)	1979-05-11
ATA544676A (de)	1979-04-15
CS182791B2 (en)	1978-05-31
KE2932A (en)	1979-03-30
NO147836B (no)	1983-03-14
FI60389B (fi)	1981-09-30
IE39537B1 (en)	1978-11-08
PH13272A (en)	1980-02-27
JPS5416491B2 (de)	1979-06-22
AU6224773A (en)	1975-05-08
HK28079A (en)	1979-05-11
CA1088931A (en)	1980-11-04
BE806995A (fr)	1974-05-07
CH597176A5 (de)	1978-03-31
FR2205335A1 (de)	1974-05-31
IL43589A (en)	1980-01-31
ATA544576A (de)	1980-06-15
DD117233A5 (de)	1976-01-05
JPS4993342A (de)	1974-09-05
NO149139B (no)	1983-11-14
FR2279729B1 (de)	1978-04-28
SE436278B (sv)	1984-11-26
HU173507B (hu)	1979-05-28
ES420325A1 (es)	1976-04-16
YU288073A (en)	1982-02-28
ZA738554B (en)	1974-09-25
GB1456513A (en)	1976-11-24
YU270680A (en)	1983-04-27
ATA936973A (de)	1981-10-15
MY7900246A (en)	1979-12-31
CS182793B2 (en)	1978-05-31
DE2365322A1 (de)	1974-11-07
DD119411A5 (de)	1976-04-20
FR2283146B1 (de)	1981-06-19

Legal Events

Date	Code	Title	Description
1997-09-16	MKEX	Expiry

Publication	Publication Date	Title
US4024179A (en)	1977-05-17	Substituted ω-pentanorprostaglandins
US3932389A (en)	1976-01-13	2-Descarboxy-2-(tetrazol-5-yl)-11-desoxy-15-substituted-.omega.-pentanorprostaglandins
CA1088930A (en)	1980-11-04	Preparation of 9-hydroxy tetrahydropyranyl substituted prostaglandin intermediates
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