CA1090531A - Stabilisation du phosphate de calcium dihydrate - Google Patents

Stabilisation du phosphate de calcium dihydrate

Info

Publication number: CA1090531A
Authority: CA; Canada
Prior art keywords: weight; phosphate dihydrate; precipitated; dimagnesium; dicalcium phosphate
Prior art date: 1976-10-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA288,991A

Other languages

English (en)

Inventor

Franz-Josef Dany

Joachim Kandler

Hedwig Prell

Joachim Wortmann

Hans W. Ziegler

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hoechst AG

Original Assignee

Hoechst AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-10-23

Filing date

1977-10-19

Publication date

1980-12-02

1977-10-19 Application filed by Hoechst AG filed Critical Hoechst AG

1980-12-02 Application granted granted Critical

1980-12-02 Publication of CA1090531A publication Critical patent/CA1090531A/fr

Status Expired legal-status Critical Current

Links

230000006641 stabilisation Effects 0.000 title abstract description 3
238000011105 stabilization Methods 0.000 title abstract description 3
XAAHAAMILDNBPS-UHFFFAOYSA-L calcium hydrogenphosphate dihydrate Chemical compound O.O.[Ca+2].OP([O-])([O-])=O XAAHAAMILDNBPS-UHFFFAOYSA-L 0.000 title abstract 6
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims abstract description 46
RBLGLDWTCZMLRW-UHFFFAOYSA-K dicalcium phosphate dihydrate Substances O.O.[Ca+2].[Ca+2].[O-]P([O-])([O-])=O RBLGLDWTCZMLRW-UHFFFAOYSA-K 0.000 claims abstract description 32
239000000243 solution Substances 0.000 claims abstract description 32
235000011007 phosphoric acid Nutrition 0.000 claims abstract description 24
PJQJKHNLFUSIGI-UHFFFAOYSA-K dimagnesium phosphate trihydrate Chemical compound O.O.O.[Mg+2].[Mg+2].[O-]P([O-])([O-])=O PJQJKHNLFUSIGI-UHFFFAOYSA-K 0.000 claims abstract description 12
150000003016 phosphoric acids Chemical class 0.000 claims abstract description 8
150000007514 bases Chemical class 0.000 claims abstract description 7
229940043430 calcium compound Drugs 0.000 claims abstract description 5
150000001674 calcium compounds Chemical class 0.000 claims abstract description 5
239000007864 aqueous solution Substances 0.000 claims abstract description 4
159000000003 magnesium salts Chemical class 0.000 claims abstract description 4
238000000034 method Methods 0.000 claims description 24
238000006243 chemical reaction Methods 0.000 claims description 22
TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 18
239000003381 stabilizer Substances 0.000 claims description 18
YIXJRHPUWRPCBB-UHFFFAOYSA-N magnesium nitrate Chemical compound [Mg+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O YIXJRHPUWRPCBB-UHFFFAOYSA-N 0.000 claims description 11
238000001556 precipitation Methods 0.000 claims description 11
229910001629 magnesium chloride Inorganic materials 0.000 claims description 9
239000000376 reactant Substances 0.000 claims description 9
239000002253 acid Substances 0.000 claims description 7
230000015572 biosynthetic process Effects 0.000 claims description 6
239000011541 reaction mixture Substances 0.000 claims description 5
230000001376 precipitating effect Effects 0.000 claims description 4
238000013019 agitation Methods 0.000 claims description 3
150000008044 alkali metal hydroxides Chemical class 0.000 claims description 3
230000000087 stabilizing effect Effects 0.000 claims description 3
BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 2
QJHZTGQRJQXVIG-UHFFFAOYSA-N O.O.O.[Mg].[Mg] Chemical compound O.O.O.[Mg].[Mg] QJHZTGQRJQXVIG-UHFFFAOYSA-N 0.000 claims description 2
229910000318 alkali metal phosphate Inorganic materials 0.000 claims description 2
239000012266 salt solution Substances 0.000 claims description 2
235000019700 dicalcium phosphate Nutrition 0.000 abstract 1
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 48
YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 13
229910052731 fluorine Inorganic materials 0.000 description 13
239000011737 fluorine Substances 0.000 description 13
VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 12
230000007062 hydrolysis Effects 0.000 description 10
238000006460 hydrolysis reaction Methods 0.000 description 10
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 9
230000000052 comparative effect Effects 0.000 description 9
229910052708 sodium Inorganic materials 0.000 description 9
239000011734 sodium Substances 0.000 description 9
UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 8
239000000203 mixture Substances 0.000 description 8
239000000047 product Substances 0.000 description 8
FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 8
235000019818 tetrasodium diphosphate Nutrition 0.000 description 8
238000007792 addition Methods 0.000 description 7
229910000019 calcium carbonate Inorganic materials 0.000 description 7
239000002244 precipitate Substances 0.000 description 6
239000000725 suspension Substances 0.000 description 6
238000001816 cooling Methods 0.000 description 5
208000002925 dental caries Diseases 0.000 description 5
229910001220 stainless steel Inorganic materials 0.000 description 5
239000010935 stainless steel Substances 0.000 description 5
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
-1 alkaline earth metal salts Chemical class 0.000 description 3
239000011575 calcium Substances 0.000 description 3
239000001110 calcium chloride Substances 0.000 description 3
229910001628 calcium chloride Inorganic materials 0.000 description 3
235000011148 calcium chloride Nutrition 0.000 description 3
230000000875 corresponding effect Effects 0.000 description 3
239000012025 fluorinating agent Substances 0.000 description 3
230000000069 prophylactic effect Effects 0.000 description 3
239000000606 toothpaste Substances 0.000 description 3
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 2
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 2
229910000147 aluminium phosphate Inorganic materials 0.000 description 2
235000001465 calcium Nutrition 0.000 description 2
229910052791 calcium Inorganic materials 0.000 description 2
229960005069 calcium Drugs 0.000 description 2
WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 description 2
229910001634 calcium fluoride Inorganic materials 0.000 description 2
229910001424 calcium ion Inorganic materials 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
238000003776 cleavage reaction Methods 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
235000019628 coolness Nutrition 0.000 description 2
230000003301 hydrolyzing effect Effects 0.000 description 2
229910052588 hydroxylapatite Inorganic materials 0.000 description 2
GVALZJMUIHGIMD-UHFFFAOYSA-H magnesium phosphate Chemical class [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GVALZJMUIHGIMD-UHFFFAOYSA-H 0.000 description 2
239000000463 material Substances 0.000 description 2
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 2
229960004838 phosphoric acid Drugs 0.000 description 2
230000007017 scission Effects 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 description 2
239000007858 starting material Substances 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
230000002411 adverse Effects 0.000 description 1
229910052783 alkali metal Inorganic materials 0.000 description 1
150000001340 alkali metals Chemical class 0.000 description 1
229910052784 alkaline earth metal Inorganic materials 0.000 description 1
229910052586 apatite Inorganic materials 0.000 description 1
AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 description 1
239000000920 calcium hydroxide Substances 0.000 description 1
235000011116 calcium hydroxide Nutrition 0.000 description 1
229910001861 calcium hydroxide Inorganic materials 0.000 description 1
ZCCIPPOKBCJFDN-UHFFFAOYSA-N calcium nitrate Inorganic materials [Ca+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ZCCIPPOKBCJFDN-UHFFFAOYSA-N 0.000 description 1
229940043256 calcium pyrophosphate Drugs 0.000 description 1
POCPYOMYXRMNGX-UHFFFAOYSA-J calcium;disodium;phosphonato phosphate Chemical compound [Na+].[Na+].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O POCPYOMYXRMNGX-UHFFFAOYSA-J 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
235000019821 dicalcium diphosphate Nutrition 0.000 description 1
CGMRCMMOCQYHAD-UHFFFAOYSA-J dicalcium hydroxide phosphate Chemical compound [OH-].[Ca++].[Ca++].[O-]P([O-])([O-])=O CGMRCMMOCQYHAD-UHFFFAOYSA-J 0.000 description 1
XZTWHWHGBBCSMX-UHFFFAOYSA-J dimagnesium;phosphonato phosphate Chemical compound [Mg+2].[Mg+2].[O-]P([O-])(=O)OP([O-])([O-])=O XZTWHWHGBBCSMX-UHFFFAOYSA-J 0.000 description 1
230000000694 effects Effects 0.000 description 1
239000000706 filtrate Substances 0.000 description 1
230000036571 hydration Effects 0.000 description 1
238000006703 hydration reaction Methods 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
239000011777 magnesium Substances 0.000 description 1
235000001055 magnesium Nutrition 0.000 description 1
229910052749 magnesium Inorganic materials 0.000 description 1
229940091250 magnesium supplement Drugs 0.000 description 1
238000012423 maintenance Methods 0.000 description 1
230000020477 pH reduction Effects 0.000 description 1
239000002245 particle Substances 0.000 description 1
VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
KWCHQJSISLQWHH-UHFFFAOYSA-N phosphoric acid;trihydrate Chemical compound O.O.O.OP(O)(O)=O KWCHQJSISLQWHH-UHFFFAOYSA-N 0.000 description 1
238000005498 polishing Methods 0.000 description 1
230000036647 reaction Effects 0.000 description 1
238000000926 separation method Methods 0.000 description 1
229910000029 sodium carbonate Inorganic materials 0.000 description 1
239000011775 sodium fluoride Substances 0.000 description 1
235000013024 sodium fluoride Nutrition 0.000 description 1
235000019982 sodium hexametaphosphate Nutrition 0.000 description 1
GCLGEJMYGQKIIW-UHFFFAOYSA-H sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 description 1
VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Inorganic materials [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 description 1
229910000162 sodium phosphate Inorganic materials 0.000 description 1
235000019832 sodium triphosphate Nutrition 0.000 description 1
239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 1
229940034610 toothpaste Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B25/00—Phosphorus; Compounds thereof
- C01B25/16—Oxyacids of phosphorus; Salts thereof
- C01B25/26—Phosphates
- C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
- C01B25/327—After-treatment
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B25/00—Phosphorus; Compounds thereof
- C01B25/16—Oxyacids of phosphorus; Salts thereof
- C01B25/26—Phosphates
- C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
- C01B25/34—Magnesium phosphates

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Inorganic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Oral & Maxillofacial Surgery (AREA)
Environmental & Geological Engineering (AREA)
General Life Sciences & Earth Sciences (AREA)
Geology (AREA)
Birds (AREA)
Epidemiology (AREA)
Cosmetics (AREA)
Paper (AREA)

CA288,991A 1976-10-23 1977-10-19 Stabilisation du phosphate de calcium dihydrate Expired CA1090531A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19762648061 DE2648061C2 (de)	1976-10-23	1976-10-23	Verfahren zum Stabilisieren von Di-calciumhydrogenphosphatdihydrat
DEP2648061.5		1976-10-23

Publications (1)

Publication Number	Publication Date
CA1090531A true CA1090531A (fr)	1980-12-02

Family

ID=5991226

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA288,991A Expired CA1090531A (fr)	1976-10-23	1977-10-19	Stabilisation du phosphate de calcium dihydrate

Country Status (6)

Country	Link
BE (1)	BE859968A (fr)
CA (1)	CA1090531A (fr)
DE (1)	DE2648061C2 (fr)
FR (1)	FR2368440A1 (fr)
GB (1)	GB1548465A (fr)
NL (1)	NL184943C (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5024825A (en) *	1989-05-13	1991-06-18	Hoechst Aktiegesellschaft	Process for the preparation of dicalcium phosphate

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0045826A1 (fr) *	1980-08-12	1982-02-17	Monsanto Company	Phosphate dicalcique dihydraté à stabilisation améliorée et procédé pour sa préparation
US4472365A (en) *	1981-06-15	1984-09-18	Stauffer Chemical Company	Dicalcium phosphate dihydrate having improved monofluorophosphate compatibility and process for the preparation thereof
EP0092929B2 (fr) *	1982-04-20	1991-05-02	Beecham Group Plc	Compositions d'hygiène orale
DE3705845A1 (de) *	1987-02-24	1988-09-01	Hoechst Ag	Zahnpasten sowie putzkoerper fuer zahnpasten auf basis dicalciumphosphat-dihydrat und ein verfahren zur herstellung solcher putzkoerper
ATE112491T1 (de)	1990-09-13	1994-10-15	Akzo Nobel Nv	Stabilisierte feste chemische zusammensetzungen.
US5292520A (en) *	1990-09-13	1994-03-08	Akzo N.V.	Stabilized solid pharmaceutical composition containing acid addition salts of a basic drug and an alkaline stabilizer
DE4305276A1 (de) *	1993-02-20	1994-08-25	Hoechst Ag	Verfahren zur Herstellung eines für den Einsatz in Zahnpasten geeigneten Dicalciumphosphat-Dihydrats
DE4306673A1 (de) *	1993-03-04	1994-09-08	Hoechst Ag	Verfahren zur Herstellung eines für den Einsatz in Zahnpasten geeigneten Dicalciumphosphat-Dihydrats

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2133286A (en) *	1937-05-11	1938-10-18	Rumford Chemical Works	Acid calcium tetraphosphate and method of making the same
US2287699A (en) *	1940-02-15	1942-06-23	Monsanto Chemicals	Stabilized dicalcium phosphate
DE1189527B (de) *	1959-06-30	1965-03-25	Stauffer Chemical Co	Verfahren zur Herstellung von stabilisiertem Dicalciumphosphat
DE1216264B (de) *	1963-09-16	1966-05-12	Knapsack Ag	Verfahren zur Herstellung von Dicalciumphosphatdihydrat
DE1224716B (de) *	1965-01-29	1966-09-15	Knapsack Ag	Verfahren zur Herstellung von Magnesiumhydrogenphosphat-Trihydrat
DE1259861B (de) *	1965-06-16	1968-02-01	Knapsack Ag	Verfahren zur Herstellung von stabilisiertem Dicalciumphosphat-Dihydrat
FR1483486A (fr) *	1965-06-16	1967-06-02	Knapsack Ag	Procédé de préparation de phosphate dicalcique dihydraté stabilisé
DE1277222B (de) *	1965-12-22	1968-09-12	Knapsack Ag	Verfahren zur Stabilisierung von Dicalciumphosphatdihydrat
DE2456808A1 (de) *	1974-11-30	1976-08-12	Henkel & Cie Gmbh	Verfahren zum stabilisieren von calcium-hydrogenphosphat-anhydrid gegen die umsetzung mit fluorionen
DE2456787A1 (de) *	1974-11-30	1976-08-12	Henkel & Cie Gmbh	Verfahren zum stabilisieren von calciumhydrogenphosphat-dihydrat gegen hydrolyse
DE2456667A1 (de) *	1974-11-30	1976-08-12	Henkel & Cie Gmbh	Verfahren zum stabilisieren von calciumhydrogenphosphat-anhydrid gegen die umsetzung mit fluorionen
DE2456693A1 (de) *	1974-11-30	1976-08-12	Henkel & Cie Gmbh	Verfahren zum stabilisieren von calcium-hydrogenphosphat-anhydrid gegen die umsetzung mit fluorionen
DE2456666A1 (de) *	1974-11-30	1976-08-12	Henkel & Cie Gmbh	Verfahren zum stabilisieren von calcium-hydrogenphosphat-dihydrat gegen hydrolyse
DE2456692A1 (de) *	1974-11-30	1976-08-12	Henkel & Cie Gmbh	Verfahren zum stabilisieren von calciumhydrogenphosphat-dihydrat gegen hydrolyse

1976
- 1976-10-23 DE DE19762648061 patent/DE2648061C2/de not_active Expired
1977
- 1977-10-18 GB GB4329377A patent/GB1548465A/en not_active Expired
- 1977-10-18 NL NL7711428A patent/NL184943C/xx not_active IP Right Cessation
- 1977-10-19 CA CA288,991A patent/CA1090531A/fr not_active Expired
- 1977-10-21 FR FR7731803A patent/FR2368440A1/fr active Granted
- 1977-10-21 BE BE181938A patent/BE859968A/fr not_active IP Right Cessation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5024825A (en) *	1989-05-13	1991-06-18	Hoechst Aktiegesellschaft	Process for the preparation of dicalcium phosphate

Also Published As

Publication number	Publication date
DE2648061C2 (de)	1982-11-04
NL184943B (nl)	1989-07-17
FR2368440A1 (fr)	1978-05-19
NL184943C (nl)	1989-12-18
GB1548465A (en)	1979-07-18
BE859968A (fr)	1978-04-21
DE2648061A1 (de)	1978-04-27
NL7711428A (nl)	1978-04-25
FR2368440B1 (fr)	1982-03-26

Legal Events

Date	Code	Title	Description
1997-12-02	MKEX	Expiry

Publication	Publication Date	Title
CA1090531A (fr)	1980-12-02	Stabilisation du phosphate de calcium dihydrate
US3442604A (en)	1969-05-06	Stabilized phosphate and dentifrice compositions and process for producing same
US3353908A (en)	1967-11-21	Process for the manufacture of dicalcium phosphate
EP0113153B1 (fr)	1987-03-18	Procédé de préparation de phosphate trimagnésien octohydraté hautement pur
US4108961A (en)	1978-08-22	Process of stabilization of anhydrous dibasic calcium phosphate against fluorine ions with azacycloalkane-2,2-diphosphonic acids
US4931272A (en)	1990-06-05	Tooth pastes, cleaning agent for tooth pastes based on dicalcium phosphate-dihydrate, and process for making such cleaning agent
US4117090A (en)	1978-09-26	Process of stabilization of dibasic calcium phosphate dihydrate against hydrolysis with azacycloalkane-2,2-diphosphonic acids
US4312843A (en)	1982-01-26	Dicalcium phosphate dihydrate having improved monofluorophosphate compatibility and process for the preparation thereof
US4193973A (en)	1980-03-18	Process for stabilization of dicalcium phosphate
US4472365A (en)	1984-09-18	Dicalcium phosphate dihydrate having improved monofluorophosphate compatibility and process for the preparation thereof
US5427756A (en)	1995-06-27	Process for the preparation of a dicalcium phosphate dihydrate suitable for use in toothpastes
US3792152A (en)	1974-02-12	Stabilized phosphate and dentifrice compositions and process for producing same
US3729546A (en)	1973-04-24	Cheese emulsifying agent
US5427755A (en)	1995-06-27	Process for the preparation of a dicalcium phosphate dihydrate suitable for use in toothpastes
CA1190378A (fr)	1985-07-16	Phosphate dicalcique dihydrate possedant une meilleure compatibilite avec monofluorophosphate
US4496527A (en)	1985-01-29	Dicalcium phosphate dihydrate having improved monofluorophosphate compatibility and process for the preparation thereof
US4487749A (en)	1984-12-11	Dicalcium phosphate dihydrate having improved monofluorophosphate compatibility and process for the preparation thereof
Bjerrum	1949	Investigations on the solubility of calcium phosphates
US4117086A (en)	1978-09-26	Process of stabilization of dibasic calcium phosphate dihydrate against hydrolysis with 3-amino-1-hydroxypropane-1,1-diphosphonic acid
US3409393A (en)	1968-11-05	Processes and compositions for conditioning phosphates
US4122151A (en)	1978-10-24	Process of stabilization of dibasic calcium phosphate dihydrate against hydrolysis with cyclic aminophosphonic acids
US3357790A (en)	1967-12-12	Calcining method for conversion of alkaline earth orthophosphates to the pyrophosphate form
JPS59207818A (ja)	1984-11-26	高純度無水第二リン酸カルシウムの製造方法
JPS58181710A (ja)	1983-10-24	アルカリモノフルオロホスフエ−トの製造方法
JP2981247B2 (ja)	1999-11-22	ピロ燐酸ナトリウムの製造方法

CA1090531A - Stabilisation du phosphate de calcium dihydrate - Google Patents

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