CA1104041A - Traduction non-disponible - Google Patents

Traduction non-disponible

Info

Publication number: CA1104041A
Authority: CA; Canada
Prior art keywords: cholesterol; enzyme preparation; preparation; esterase; polyethoxy ethanol
Prior art date: 1977-02-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA294,608A

Other languages

English (en)

Inventor

Charles T. Goodhue

Theodore W. Esders

Christine A. Michrina

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eastman Kodak Co

Original Assignee

Eastman Kodak Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-02-03

Filing date

1978-01-09

Publication date

1981-06-30

1978-01-09 Application filed by Eastman Kodak Co filed Critical Eastman Kodak Co

1981-06-30 Application granted granted Critical

1981-06-30 Publication of CA1104041A publication Critical patent/CA1104041A/fr

Status Expired legal-status Critical Current

Links

150000001840 cholesterol esters Chemical class 0.000 title claims abstract description 41
230000007065 protein hydrolysis Effects 0.000 title description 3
238000002360 preparation method Methods 0.000 claims abstract description 51
239000000203 mixture Substances 0.000 claims abstract description 47
238000000034 method Methods 0.000 claims abstract description 45
102000004190 Enzymes Human genes 0.000 claims abstract description 38
108090000790 Enzymes Proteins 0.000 claims abstract description 38
239000004094 surface-active agent Substances 0.000 claims abstract description 37
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 33
230000007062 hydrolysis Effects 0.000 claims abstract description 33
238000006460 hydrolysis reaction Methods 0.000 claims abstract description 33
102000004169 proteins and genes Human genes 0.000 claims abstract description 25
108090000623 proteins and genes Proteins 0.000 claims abstract description 25
108010055297 Sterol Esterase Proteins 0.000 claims abstract description 23
102000000019 Sterol Esterase Human genes 0.000 claims abstract description 23
210000002966 serum Anatomy 0.000 claims abstract description 21
230000000694 effects Effects 0.000 claims abstract description 20
230000008569 process Effects 0.000 claims abstract description 18
230000003301 hydrolyzing effect Effects 0.000 claims abstract description 15
-1 polyoxyethylene chain Polymers 0.000 claims abstract description 12
125000006353 oxyethylene group Chemical group 0.000 claims abstract description 11
239000012636 effector Substances 0.000 claims abstract description 8
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical class C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 50
229940107161 cholesterol Drugs 0.000 claims description 20
235000012000 cholesterol Nutrition 0.000 claims description 20
108090000371 Esterases Proteins 0.000 claims description 14
241000222175 Diutina rugosa Species 0.000 claims description 12
230000000813 microbial effect Effects 0.000 claims description 10
238000003556 assay Methods 0.000 claims description 8
150000002148 esters Chemical class 0.000 claims description 8
239000003153 chemical reaction reagent Substances 0.000 claims description 7
238000001514 detection method Methods 0.000 claims description 6
230000007480 spreading Effects 0.000 claims description 6
238000003892 spreading Methods 0.000 claims description 6
241000146387 Chromobacterium viscosum Species 0.000 claims description 5
241001465754 Metazoa Species 0.000 claims description 5
240000005384 Rhizopus oryzae Species 0.000 claims description 5
235000013752 Rhizopus oryzae Nutrition 0.000 claims description 5
125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 claims description 5
UYDLBVPAAFVANX-UHFFFAOYSA-N octylphenoxy polyethoxyethanol Chemical group CC(C)(C)CC(C)(C)C1=CC=C(OCCOCCOCCOCCO)C=C1 UYDLBVPAAFVANX-UHFFFAOYSA-N 0.000 claims description 4
239000012736 aqueous medium Substances 0.000 claims 4
108090001060 Lipase Proteins 0.000 description 23
102000004882 Lipase Human genes 0.000 description 23
239000004367 Lipase Substances 0.000 description 22
229940088598 enzyme Drugs 0.000 description 22
229940040461 lipase Drugs 0.000 description 22
235000019421 lipase Nutrition 0.000 description 22
239000010410 layer Substances 0.000 description 21
239000012530 fluid Substances 0.000 description 13
235000018102 proteins Nutrition 0.000 description 13
108091005804 Peptidases Proteins 0.000 description 12
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 12
239000000463 material Substances 0.000 description 12
239000004365 Protease Substances 0.000 description 11
238000012360 testing method Methods 0.000 description 11
229940079919 digestives enzyme preparation Drugs 0.000 description 9
235000019441 ethanol Nutrition 0.000 description 7
150000003626 triacylglycerols Chemical class 0.000 description 7
238000006243 chemical reaction Methods 0.000 description 6
239000000306 component Substances 0.000 description 6
SNRUBQQJIBEYMU-UHFFFAOYSA-N dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 5
239000000243 solution Substances 0.000 description 5
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 5
108010089254 Cholesterol oxidase Proteins 0.000 description 4
LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 4
238000011534 incubation Methods 0.000 description 4
150000002632 lipids Chemical class 0.000 description 4
239000000758 substrate Substances 0.000 description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 3
102000019280 Pancreatic lipases Human genes 0.000 description 3
108050006759 Pancreatic lipases Proteins 0.000 description 3
102000003992 Peroxidases Human genes 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
239000003833 bile salt Substances 0.000 description 3
239000003795 chemical substances by application Substances 0.000 description 3
230000000052 comparative effect Effects 0.000 description 3
239000000839 emulsion Substances 0.000 description 3
238000010931 ester hydrolysis Methods 0.000 description 3
229940116369 pancreatic lipase Drugs 0.000 description 3
108040007629 peroxidase activity proteins Proteins 0.000 description 3
238000007430 reference method Methods 0.000 description 3
241000222120 Candida <Saccharomycetales> Species 0.000 description 2
108010051152 Carboxylesterase Proteins 0.000 description 2
102000013392 Carboxylesterase Human genes 0.000 description 2
241000272194 Ciconiiformes Species 0.000 description 2
102000004157 Hydrolases Human genes 0.000 description 2
108090000604 Hydrolases Proteins 0.000 description 2
102000007330 LDL Lipoproteins Human genes 0.000 description 2
108010007622 LDL Lipoproteins Proteins 0.000 description 2
229920004890 Triton X-100 Polymers 0.000 description 2
238000002835 absorbance Methods 0.000 description 2
239000002250 absorbent Substances 0.000 description 2
230000002745 absorbent Effects 0.000 description 2
230000003213 activating effect Effects 0.000 description 2
239000012491 analyte Substances 0.000 description 2
229940093761 bile salts Drugs 0.000 description 2
210000001124 body fluid Anatomy 0.000 description 2
239000010839 body fluid Substances 0.000 description 2
238000009835 boiling Methods 0.000 description 2
125000004432 carbon atom Chemical group C* 0.000 description 2
238000006911 enzymatic reaction Methods 0.000 description 2
229940074391 gallic acid Drugs 0.000 description 2
235000004515 gallic acid Nutrition 0.000 description 2
150000002500 ions Chemical class 0.000 description 2
239000007788 liquid Substances 0.000 description 2
WDGFFVCWBZVLCE-UHFFFAOYSA-N purpurogallin Chemical group C1=CC=C(O)C(=O)C2=C1C=C(O)C(O)=C2O WDGFFVCWBZVLCE-UHFFFAOYSA-N 0.000 description 2
238000012216 screening Methods 0.000 description 2
LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 2
OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 description 1
IDOQDZANRZQBTP-UHFFFAOYSA-N 2-[2-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanol Chemical compound CC(C)(C)CC(C)(C)C1=CC=CC=C1OCCO IDOQDZANRZQBTP-UHFFFAOYSA-N 0.000 description 1
RLFWWDJHLFCNIJ-UHFFFAOYSA-N 4-aminoantipyrine Chemical compound CN1C(C)=C(N)C(=O)N1C1=CC=CC=C1 RLFWWDJHLFCNIJ-UHFFFAOYSA-N 0.000 description 1
241001409016 Arrhis Species 0.000 description 1
241000228212 Aspergillus Species 0.000 description 1
241000196324 Embryophyta Species 0.000 description 1
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
108010010803 Gelatin Proteins 0.000 description 1
AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
NAACPBBQTFFYQB-UHFFFAOYSA-N Linolsaeure-cholesterylester Natural products C12CCC3(C)C(C(C)CCCC(C)C)CCC3C2CC=C2C1(C)CCC(OC(=O)CCCCCCCC=CCC=CCCCCC)C2 NAACPBBQTFFYQB-UHFFFAOYSA-N 0.000 description 1
241000187654 Nocardia Species 0.000 description 1
241000589540 Pseudomonas fluorescens Species 0.000 description 1
241000235527 Rhizopus Species 0.000 description 1
DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
UBDJSBRKNHQFPD-PYGYYAGESA-N Taurodehydrocholic acid Chemical compound C1CC(=O)C[C@H]2CC(=O)[C@H]3[C@@H]4CC[C@H]([C@@H](CCC(=O)NCCS(O)(=O)=O)C)[C@@]4(C)C(=O)C[C@@H]3[C@]21C UBDJSBRKNHQFPD-PYGYYAGESA-N 0.000 description 1
241000209140 Triticum Species 0.000 description 1
235000021307 Triticum Nutrition 0.000 description 1
239000013504 Triton X-100 Substances 0.000 description 1
229920004892 Triton X-102 Polymers 0.000 description 1
229920004929 Triton X-114 Polymers 0.000 description 1
230000009471 action Effects 0.000 description 1
229910052783 alkali metal Inorganic materials 0.000 description 1
150000001340 alkali metals Chemical class 0.000 description 1
229910052784 alkaline earth metal Inorganic materials 0.000 description 1
125000000217 alkyl group Chemical group 0.000 description 1
150000008051 alkyl sulfates Chemical class 0.000 description 1
239000002585 base Substances 0.000 description 1
239000011230 binding agent Substances 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
239000003518 caustics Substances 0.000 description 1
230000008859 change Effects 0.000 description 1
GGCLNOIGPMGLDB-GYKMGIIDSA-N cholest-5-en-3-one Chemical compound C1C=C2CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 GGCLNOIGPMGLDB-GYKMGIIDSA-N 0.000 description 1
NYOXRYYXRWJDKP-UHFFFAOYSA-N cholestenone Natural products C1CC2=CC(=O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 NYOXRYYXRWJDKP-UHFFFAOYSA-N 0.000 description 1
NAACPBBQTFFYQB-XNTGVSEISA-N cholesteryl octadeca-9,12-dienoate Chemical compound C([C@@H]12)C[C@]3(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@H]3[C@@H]1CC=C1[C@]2(C)CC[C@H](OC(=O)CCCCCCCC=CCC=CCCCCC)C1 NAACPBBQTFFYQB-XNTGVSEISA-N 0.000 description 1
229940009976 deoxycholate Drugs 0.000 description 1
KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 description 1
238000011161 development Methods 0.000 description 1
238000010494 dissociation reaction Methods 0.000 description 1
230000005593 dissociations Effects 0.000 description 1
230000002255 enzymatic effect Effects 0.000 description 1
238000011156 evaluation Methods 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
230000009931 harmful effect Effects 0.000 description 1
230000002452 interceptive effect Effects 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
ZUVBIBLYOCVYJU-UHFFFAOYSA-N naphthalene-1,7-diol Chemical compound C1=CC=C(O)C2=CC(O)=CC=C21 ZUVBIBLYOCVYJU-UHFFFAOYSA-N 0.000 description 1
125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
238000005457 optimization Methods 0.000 description 1
229910000160 potassium phosphate Inorganic materials 0.000 description 1
235000011009 potassium phosphates Nutrition 0.000 description 1
235000004252 protein component Nutrition 0.000 description 1
238000011002 quantification Methods 0.000 description 1
VMXUWOKSQNHOCA-UKTHLTGXSA-N ranitidine Chemical compound [O-][N+](=O)\C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-UKTHLTGXSA-N 0.000 description 1
230000035484 reaction time Effects 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
239000002356 single layer Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
239000011734 sodium Substances 0.000 description 1
108010079522 solysime Proteins 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1
108091016642 steapsin Proteins 0.000 description 1
239000000126 substance Substances 0.000 description 1
WBWWGRHZICKQGZ-HZAMXZRMSA-N taurocholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS(O)(=O)=O)C)[C@@]2(C)[C@@H](O)C1 WBWWGRHZICKQGZ-HZAMXZRMSA-N 0.000 description 1
GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Analytical Chemistry (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

CA294,608A 1977-02-03 1978-01-09 Traduction non-disponible Expired CA1104041A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US76516877A	1977-02-03	1977-02-03
US765,168		1977-02-03

Publications (1)

Publication Number	Publication Date
CA1104041A true CA1104041A (fr)	1981-06-30

Family

ID=25072829

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA294,608A Expired CA1104041A (fr)	1977-02-03	1978-01-09	Traduction non-disponible

Country Status (7)

Country	Link
JP (1)	JPS5396378A (fr)
BE (1)	BE863657A (fr)
CA (1)	CA1104041A (fr)
DE (1)	DE2804356C2 (fr)
FR (1)	FR2379815A1 (fr)
GB (1)	GB1592632A (fr)
SE (2)	SE468093B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3208253A1 (de) *	1982-03-08	1983-09-15	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur spezifischen bestimmung des cholesterins der ldl-fraktion im serum
GB2154735B (en) *	1984-01-27	1987-07-15	Menarini Sas	Reagent for determining blood glucose content
IT1177513B (it) *	1984-01-27	1987-08-26	Menarini Sas	Reattivo liquido pronto per l'uso per la determinazione del contenuto di glucosio nel sangue
EP0218083A1 (fr) *	1985-09-03	1987-04-15	Abbott Laboratories	Réactif stabilisé pour le cholestérol et méthode de détermination du cholestérol total par utilisation du réactif

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5621391B2 (fr) *	1971-09-22	1981-05-19
US4186251A (en) *	1973-03-01	1980-01-29	Miles Laboratories, Inc.	Composition and method for determination of cholesterol
DE2315501C3 (de) *	1973-03-28	1980-02-21	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur Bestimmung von Cholesterin
US4164448A (en) *	1973-12-07	1979-08-14	Boehringer Mannheim Gmbh	Activation of cholesterol oxidase for cholesterol assay
DE2361169C3 (de) *	1973-12-07	1978-09-14	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur Aktivierung von von Detengensspuren befreiter Cholesterinoxydase
GB1479994A (en) *	1974-03-04	1977-07-13	Abbott Lab	Single reagent for the enzymatic determination of cholesterol and method therefor
US3884764A (en) *	1974-03-25	1975-05-20	Eastman Kodak Co	Method and composition for blood serum cholesterol analysis
JPS6134800B2 (fr) *	1974-03-28	1986-08-09	Boehringer Mannheim Gmbh
JPS5813159B2 (ja) *	1975-07-03	1983-03-11	ナガセサンギヨウカブシキガイシヤ	コレステロ−ルエステラ−ゼオモチイルコレステロ−ルノテイリヨウホウ

1978
- 1978-01-09 CA CA294,608A patent/CA1104041A/fr not_active Expired
- 1978-02-02 GB GB4302/78A patent/GB1592632A/en not_active Expired
- 1978-02-02 DE DE2804356A patent/DE2804356C2/de not_active Expired - Fee Related
- 1978-02-02 JP JP995878A patent/JPS5396378A/ja active Granted
- 1978-02-02 SE SE7801248A patent/SE468093B/xx not_active IP Right Cessation
- 1978-02-03 FR FR7803002A patent/FR2379815A1/fr active Granted
- 1978-02-03 BE BE184909A patent/BE863657A/fr not_active IP Right Cessation
1983
- 1983-06-10 SE SE8303292A patent/SE462047B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
SE7801248L (sv)	1978-08-04
JPS5396378A (en)	1978-08-23
JPS6237957B2 (fr)	1987-08-14
BE863657A (fr)	1978-08-03
SE8303292D0 (sv)	1983-06-10
DE2804356A1 (de)	1978-08-10
SE462047B (sv)	1990-04-30
GB1592632A (en)	1981-07-08
SE8303292L (sv)	1983-06-10
DE2804356C2 (de)	1995-07-13
FR2379815B1 (fr)	1982-01-08
FR2379815A1 (fr)	1978-09-01
SE468093B (sv)	1992-11-02

Legal Events

Date	Code	Title	Description
1998-06-30	MKEX	Expiry

Publication	Publication Date	Title
US4275152A (en)	1981-06-23	Hydrolysis of protein-bound cholesterol esters
CA1138312A (fr)	1982-12-28	Compose et methode pour le dosage du cholesterol
Dennis	1983	9 Phospholipases
Taguchi et al.	1978	Phosphatidyl inositol-specific phospholipase C from Clostridium novyi type A
Hiroh et al.	1978	Studies on sphingomyelinase of Bacillus cereus I. Purification and properties
CA1067804A (fr)	1979-12-11	Methode de dosage du cholesterol
US4259440A (en)	1981-03-31	Hydrolysis and assay of triglycerides
US4241178A (en)	1980-12-23	Process and composition for the quantification of glycerol ATP and triglycerides
CA1054907A (fr)	1979-05-22	Methode et compose pour l'analyse de serum sanguin
US4179334A (en)	1979-12-18	Hydrolysis of protein-bound triglycerides
US3898130A (en)	1975-08-05	Rapid enzymatic hydrolysis of triglycerides
Kyger et al.	1984	Nonspecific inhibition of enzymes by p-bromophenacyl bromide inhibition of human platelet phospholipase C and modification of sulfhydryl groups
Linder et al.	1982	Enzymatic oxidation of membrane cholesterol in relation to lysis of sheep erythrocytes by corynebacterial enzymes
CA1104041A (fr)	1981-06-30	Traduction non-disponible
US4275151A (en)	1981-06-23	Hydrolysis of protein-bound cholesterol esters
Hori et al.	1977	Latency of microsomal hexose-6-phosphate dehydrogenase
US3869349A (en)	1975-03-04	Method for the enzymatic hydrolysis of cholesterol esters
US5559003A (en)	1996-09-24	Assay method for biological components
Thurnhofer et al.	1986	Cholesterol oxidase as a structural probe of biological membranes: its application to brush-border membrane
CA1100023A (fr)	1981-04-28	Procede et composition pour le dosage du glycerol et des triglycerides
Goi et al.	2000	Membrane anchoring and surface distribution of glycohydrolases of human erythrocyte membranes
US4499184A (en)	1985-02-12	Analysis for total cholesterol using lecithin:cholesterol acyl transferase (LCAT)
Scanlin et al.	1979	Abnormal distribution of α-l-fucosidase in cystic fibrosis: decreased activity in serum
JPS6134800B2 (fr)	1986-08-09
Okabe et al.	1980	o-Toluoylcholine as substrate for measurement of serum pseudo-cholinesterase activity