CA1120835A - Multiple analysis hematology reference control reagent and method of making the same - Google Patents

Multiple analysis hematology reference control reagent and method of making the same

Info

Publication number: CA1120835A
Authority: CA; Canada
Prior art keywords: reference control; urea; control; platelet; suspension
Prior art date: 1978-06-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000329726A

Other languages

English (en)

French (fr)

Inventor

Alan H. Runck

Douglas Armstrong

James T. Hutchisson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Coulter Electronics Inc

Original Assignee

Coulter Electronics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-06-15

Filing date

1979-06-14

Publication date

1982-03-30

1979-06-06 Priority claimed from US06/044,841 external-priority patent/US4219440A/en

1979-06-14 Application filed by Coulter Electronics Inc filed Critical Coulter Electronics Inc

1982-03-30 Application granted granted Critical

1982-03-30 Publication of CA1120835A publication Critical patent/CA1120835A/en

Status Expired legal-status Critical Current

Links

239000013643 reference control Substances 0.000 title claims abstract description 52
238000004519 manufacturing process Methods 0.000 title claims abstract description 4
238000004458 analytical method Methods 0.000 title claims abstract 4
239000003153 chemical reaction reagent Substances 0.000 title abstract description 21
210000001772 blood platelet Anatomy 0.000 claims abstract description 98
210000003743 erythrocyte Anatomy 0.000 claims abstract description 54
210000004369 blood Anatomy 0.000 claims abstract description 50
239000008280 blood Substances 0.000 claims abstract description 50
238000000034 method Methods 0.000 claims abstract description 18
238000005259 measurement Methods 0.000 claims abstract description 13
238000012544 monitoring process Methods 0.000 claims abstract description 10
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 71
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 55
239000004202 carbamide Substances 0.000 claims description 55
239000000725 suspension Substances 0.000 claims description 44
239000011780 sodium chloride Substances 0.000 claims description 37
241001465754 Metazoa Species 0.000 claims description 14
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
230000001627 detrimental effect Effects 0.000 claims description 7
239000000203 mixture Substances 0.000 claims description 7
238000012360 testing method Methods 0.000 claims description 5
235000021120 animal protein Nutrition 0.000 claims description 4
230000002939 deleterious effect Effects 0.000 claims description 4
239000012460 protein solution Substances 0.000 claims description 4
230000002489 hematologic effect Effects 0.000 claims description 2
150000003839 salts Chemical class 0.000 claims description 2
150000003841 chloride salts Chemical class 0.000 claims 5
210000002381 plasma Anatomy 0.000 claims 2
210000004027 cell Anatomy 0.000 abstract description 23
210000000265 leukocyte Anatomy 0.000 abstract description 16
102000001554 Hemoglobins Human genes 0.000 abstract description 14
108010054147 Hemoglobins Proteins 0.000 abstract description 14
238000004820 blood count Methods 0.000 abstract description 9
238000009826 distribution Methods 0.000 abstract description 9
238000005534 hematocrit Methods 0.000 abstract description 9
238000002405 diagnostic procedure Methods 0.000 abstract description 4
239000004615 ingredient Substances 0.000 abstract description 2
230000002452 interceptive effect Effects 0.000 abstract description 2
239000000463 material Substances 0.000 description 12
239000000243 solution Substances 0.000 description 8
239000000126 substance Substances 0.000 description 8
239000006285 cell suspension Substances 0.000 description 7
239000000047 product Substances 0.000 description 5
239000003085 diluting agent Substances 0.000 description 4
239000012153 distilled water Substances 0.000 description 3
230000002934 lysing effect Effects 0.000 description 3
239000003755 preservative agent Substances 0.000 description 3
SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 2
239000002253 acid Substances 0.000 description 2
230000008901 benefit Effects 0.000 description 2
239000010836 blood and blood product Substances 0.000 description 2
210000000601 blood cell Anatomy 0.000 description 2
229940125691 blood product Drugs 0.000 description 2
230000000694 effects Effects 0.000 description 2
239000000834 fixative Substances 0.000 description 2
210000005260 human cell Anatomy 0.000 description 2
WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 2
238000000386 microscopy Methods 0.000 description 2
230000002335 preservative effect Effects 0.000 description 2
239000003381 stabilizer Substances 0.000 description 2
206010018910 Haemolysis Diseases 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
COQLPRJCUIATTQ-UHFFFAOYSA-N Uranyl acetate Chemical compound O.O.O=[U]=O.CC(O)=O.CC(O)=O COQLPRJCUIATTQ-UHFFFAOYSA-N 0.000 description 1
230000000740 bleeding effect Effects 0.000 description 1
238000004159 blood analysis Methods 0.000 description 1
239000012503 blood component Substances 0.000 description 1
210000001217 buttock Anatomy 0.000 description 1
239000006227 byproduct Substances 0.000 description 1
230000001413 cellular effect Effects 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
239000000306 component Substances 0.000 description 1
230000001143 conditioned effect Effects 0.000 description 1
239000012895 dilution Substances 0.000 description 1
238000010790 dilution Methods 0.000 description 1
239000003792 electrolyte Substances 0.000 description 1
239000012530 fluid Substances 0.000 description 1
102000018146 globin Human genes 0.000 description 1
108060003196 globin Proteins 0.000 description 1
230000008588 hemolysis Effects 0.000 description 1
239000003112 inhibitor Substances 0.000 description 1
239000002207 metabolite Substances 0.000 description 1
230000003204 osmotic effect Effects 0.000 description 1
239000002245 particle Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
238000003908 quality control method Methods 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
239000011734 sodium Substances 0.000 description 1
230000000087 stabilizing effect Effects 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000003860 storage Methods 0.000 description 1
239000000758 substrate Substances 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2496/00—Reference solutions for assays of biological material
- G01N2496/05—Reference solutions for assays of biological material containing blood cells or plasma

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Hematology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)

CA000329726A 1978-06-15 1979-06-14 Multiple analysis hematology reference control reagent and method of making the same Expired CA1120835A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US91576178A	1978-06-15	1978-06-15
US915,761		1978-06-15
US06/044,841 US4219440A (en)	1979-06-06	1979-06-06	Multiple analysis hematology reference control reagent and method of making the same
US44,841		1979-06-06

Publications (1)

Publication Number	Publication Date
CA1120835A true CA1120835A (en)	1982-03-30

Family

ID=26722060

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000329726A Expired CA1120835A (en)	1978-06-15	1979-06-14	Multiple analysis hematology reference control reagent and method of making the same

Country Status (11)

Country	Link
AU (1)	AU525932B2 (da)
CA (1)	CA1120835A (da)
DE (1)	DE2923957A1 (da)
DK (1)	DK248679A (da)
ES (1)	ES481548A1 (da)
FR (1)	FR2432172A1 (da)
GB (1)	GB2023287B (da)
IL (1)	IL57562A0 (da)
IT (1)	IT1117245B (da)
NL (1)	NL7904656A (da)
SE (1)	SE7905238L (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4264470A (en) *	1979-05-07	1981-04-28	Coulter Electronics, Inc.	Selecting goat erythrocytes to simulate human platelets in hematologic reference controls
US6174728B1 (en)	1998-04-03	2001-01-16	Avl Medical Instruments Ag	Control or calibration standard for use with instruments for optical measurement of hemoglobin concentration in blood samples

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3558522A (en) *	1969-03-05	1971-01-26	Baxter Laboratories Inc	Hematology control standard comprising washed red blood cells and synthetic latex particles
US3640896A (en) *	1970-04-13	1972-02-08	Pfizer	Process for stabilizing fowl red blood cells
US3873467A (en) *	1974-02-01	1975-03-25	United Medical Lab Inc	Hematologic reference control
US4160644A (en) *	1977-06-13	1979-07-10	Streck Laboratories, Inc.	Platelet reference control and method of preparation

1979
- 1979-06-13 DE DE19792923957 patent/DE2923957A1/de not_active Withdrawn
- 1979-06-13 ES ES481548A patent/ES481548A1/es not_active Expired
- 1979-06-14 IT IT49424/79A patent/IT1117245B/it active
- 1979-06-14 NL NL7904656A patent/NL7904656A/xx not_active Application Discontinuation
- 1979-06-14 FR FR7915259A patent/FR2432172A1/fr not_active Withdrawn
- 1979-06-14 CA CA000329726A patent/CA1120835A/en not_active Expired
- 1979-06-14 AU AU48067/79A patent/AU525932B2/en not_active Ceased
- 1979-06-14 DK DK248679A patent/DK248679A/da not_active Application Discontinuation
- 1979-06-14 IL IL57562A patent/IL57562A0/xx unknown
- 1979-06-14 SE SE7905238A patent/SE7905238L/ not_active Application Discontinuation
- 1979-06-14 GB GB7920790A patent/GB2023287B/en not_active Expired

Also Published As

Publication number	Publication date
FR2432172A1 (fr)	1980-02-22
DK248679A (da)	1979-12-16
AU525932B2 (en)	1982-12-09
ES481548A1 (es)	1980-07-01
GB2023287A (en)	1979-12-28
NL7904656A (nl)	1979-12-18
DE2923957A1 (de)	1980-01-03
GB2023287B (en)	1982-12-15
IL57562A0 (en)	1979-10-31
SE7905238L (sv)	1979-12-16
IT7949424A0 (it)	1979-06-14
IT1117245B (it)	1986-02-17
AU4806779A (en)	1979-12-20

Legal Events

Date	Code	Title	Description
1999-03-30	MKEX	Expiry

Publication	Publication Date	Title
US4219440A (en)	1980-08-26	Multiple analysis hematology reference control reagent and method of making the same
DE60035053T2 (de)	2008-01-31	Hämatologische kontrolle und system für hämatologische viel-parameter-messungen
US5320965A (en)	1994-06-14	Stable hemoglobin reference solution
CA1117401A (en)	1982-02-02	Multi-purpose blood diluent for use in electronic blood analysis instrumentation
US3962125A (en)	1976-06-08	Multi-purpose diluent for use in blood analysis by electronic instrumentation of the coulter type
EP0305491B1 (en)	1996-02-07	System for isolating and identifying leukocytes
CA1222679A (en)	1987-06-09	Reagent for combined diluting and lysing whole blood
US3640896A (en)	1972-02-08	Process for stabilizing fowl red blood cells
US3574137A (en)	1971-04-06	Multiple-analysis hematology control comprising human red blood cells and fowl red blood cells in an anticoagulant containing human serologically compatible plasma medium
CA1126154A (en)	1982-06-22	Hematological reference control compositions containing goat erythrocytes to simulate human platelets
CA2129832A1 (en)	1993-08-25	Hematology control composition for leukocyte analogs; and method for their preparation and use
WO2005100979A1 (en)	2005-10-27	Reference control containing a nucleated red blood cell component
EP0154522B1 (en)	1991-08-28	Method for sphering and fixing whole blood erythrocytes
EP2002256A2 (en)	2008-12-17	Reference control composition containing a nucleated red blood cell component made of non-nucleated blood cells
Carrington et al.	1959	Chemical constituents of haemolymph and tissue in Telea polyphemus Cram. with particular reference to the question of ion binding
EP0049478B1 (en)	1985-08-21	Multi-purpose blood diluent
Srivastava et al.	1979	Haematological Anomalies in a Fresh Water Teleost, Colisafasciatus, on Acute Exposure to Cobalt
US4244837A (en)	1981-01-13	Multi-purpose blood diluent for use in electronic blood analysis instrumentation
Leard et al.	1990	The effect of haemolysis on certain canine serum chemistry parameters
Steyn et al.	1975	Standard serum chemical and haematological values in the chacma baboon (Papio ursinus)
CA1233096A (en)	1988-02-23	One step method for sphering and fixing whole blood erythrocytes
RU2717313C1 (ru)	2020-03-20	Способ определения резистентности эритроцитов
Allen	1994	Evaluation of a technique for sampling blood from small fishes
Lanning	2000	Toxicological Pathology
ES481548A1 (es)	1980-07-01	Metodo para preparar un control de referencia hematologico.