CA1120861A - Bactericide cathionique avec additif de sapidite employe dans les produits d'hygiene buccale - Google Patents

Bactericide cathionique avec additif de sapidite employe dans les produits d'hygiene buccale

Info

Publication number: CA1120861A
Authority: CA; Canada
Prior art keywords: masking; oral product; weight; product according; oil
Prior art date: 1978-11-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000338888A

Other languages

English (en)

Inventor

Alok K. Ray

Charles A. Watson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Unilever PLC

Original Assignee

Unilever PLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-11-01

Filing date

1979-10-31

Publication date

1982-03-30

1979-10-31 Application filed by Unilever PLC filed Critical Unilever PLC

1982-03-30 Application granted granted Critical

1982-03-30 Publication of CA1120861A publication Critical patent/CA1120861A/fr

Status Expired legal-status Critical Current

Links

239000000796 flavoring agent Substances 0.000 title claims abstract description 43
239000013588 oral product Substances 0.000 title claims abstract description 28
230000002070 germicidal effect Effects 0.000 title claims abstract description 23
229940023486 oral product Drugs 0.000 title claims abstract description 23
125000002091 cationic group Chemical group 0.000 title claims abstract description 17
230000000873 masking effect Effects 0.000 title claims abstract description 9
239000000203 mixture Substances 0.000 claims abstract description 48
ZCTQGTTXIYCGGC-UHFFFAOYSA-N Benzyl salicylate Chemical compound OC1=CC=CC=C1C(=O)OCC1=CC=CC=C1 ZCTQGTTXIYCGGC-UHFFFAOYSA-N 0.000 claims abstract description 28
235000019499 Citrus oil Nutrition 0.000 claims abstract description 14
235000019596 Masking bitterness Nutrition 0.000 claims abstract description 14
239000010500 citrus oil Substances 0.000 claims abstract description 14
MSHFRERJPWKJFX-UHFFFAOYSA-N 4-Methoxybenzyl alcohol Chemical compound COC1=CC=C(CO)C=C1 MSHFRERJPWKJFX-UHFFFAOYSA-N 0.000 claims abstract description 12
239000000470 constituent Substances 0.000 claims abstract description 10
239000001279 citrus aurantifolia swingle expressed oil Substances 0.000 claims abstract description 9
239000002324 mouth wash Substances 0.000 claims abstract description 6
229940051866 mouthwash Drugs 0.000 claims abstract description 3
235000019658 bitter taste Nutrition 0.000 claims description 10
NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 6
NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 6
229940041616 menthol Drugs 0.000 claims description 6
229940123208 Biguanide Drugs 0.000 claims description 4
235000005979 Citrus limon Nutrition 0.000 claims description 4
244000131522 Citrus pyriformis Species 0.000 claims description 4
239000000047 product Substances 0.000 claims description 4
244000246386 Mentha pulegium Species 0.000 claims description 3
235000016257 Mentha pulegium Nutrition 0.000 claims description 3
235000004357 Mentha x piperita Nutrition 0.000 claims description 3
235000001050 hortel pimenta Nutrition 0.000 claims description 3
239000003921 oil Substances 0.000 claims description 3
235000019198 oils Nutrition 0.000 claims description 3
239000000341 volatile oil Substances 0.000 claims description 3
241001672694 Citrus reticulata Species 0.000 claims description 2
240000000560 Citrus x paradisi Species 0.000 claims description 2
238000004519 manufacturing process Methods 0.000 claims 1
239000008368 mint flavor Substances 0.000 claims 1
239000000551 dentifrice Substances 0.000 abstract description 7
235000019634 flavors Nutrition 0.000 description 12
RUVINXPYWBROJD-ONEGZZNKSA-N trans-anethole Chemical compound COC1=CC=C(\C=C\C)C=C1 RUVINXPYWBROJD-ONEGZZNKSA-N 0.000 description 10
238000009472 formulation Methods 0.000 description 8
150000004283 biguanides Chemical group 0.000 description 6
229960003260 chlorhexidine Drugs 0.000 description 6
RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 6
VLKZOEOYAKHREP-UHFFFAOYSA-N hexane Substances CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 6
OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 6
GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 5
WEEGYLXZBRQIMU-UHFFFAOYSA-N Eucalyptol Chemical compound C1CC2CCC1(C)OC2(C)C WEEGYLXZBRQIMU-UHFFFAOYSA-N 0.000 description 5
235000019501 Lemon oil Nutrition 0.000 description 5
229940011037 anethole Drugs 0.000 description 5
229960005233 cineole Drugs 0.000 description 5
RFFOTVCVTJUTAD-UHFFFAOYSA-N cineole Natural products C1CC2(C)CCC1(C(C)C)O2 RFFOTVCVTJUTAD-UHFFFAOYSA-N 0.000 description 5
239000010501 lemon oil Substances 0.000 description 5
239000001525 mentha piperita l. herb oil Substances 0.000 description 5
RUVINXPYWBROJD-UHFFFAOYSA-N para-methoxyphenyl Natural products COC1=CC=C(C=CC)C=C1 RUVINXPYWBROJD-UHFFFAOYSA-N 0.000 description 5
235000019477 peppermint oil Nutrition 0.000 description 5
238000002360 preparation method Methods 0.000 description 5
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
NFLGAXVYCFJBMK-RKDXNWHRSA-N (+)-isomenthone Natural products CC(C)[C@H]1CC[C@@H](C)CC1=O NFLGAXVYCFJBMK-RKDXNWHRSA-N 0.000 description 3
NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 3
YIKYNHJUKRTCJL-UHFFFAOYSA-N Ethyl maltol Chemical compound CCC=1OC=CC(=O)C=1O YIKYNHJUKRTCJL-UHFFFAOYSA-N 0.000 description 3
239000005770 Eugenol Substances 0.000 description 3
NFLGAXVYCFJBMK-UHFFFAOYSA-N Menthone Chemical compound CC(C)C1CCC(C)CC1=O NFLGAXVYCFJBMK-UHFFFAOYSA-N 0.000 description 3
UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 3
150000001875 compounds Chemical class 0.000 description 3
229940093503 ethyl maltol Drugs 0.000 description 3
229960002217 eugenol Drugs 0.000 description 3
239000001683 mentha spicata herb oil Substances 0.000 description 3
229930007503 menthone Natural products 0.000 description 3
229960001047 methyl salicylate Drugs 0.000 description 3
235000019721 spearmint oil Nutrition 0.000 description 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
241000207199 Citrus Species 0.000 description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
235000019502 Orange oil Nutrition 0.000 description 2
GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
235000020971 citrus fruits Nutrition 0.000 description 2
CBOQJANXLMLOSS-UHFFFAOYSA-N ethyl vanillin Chemical compound CCOC1=CC(C=O)=CC=C1O CBOQJANXLMLOSS-UHFFFAOYSA-N 0.000 description 2
235000011187 glycerol Nutrition 0.000 description 2
239000004615 ingredient Substances 0.000 description 2
239000010502 orange oil Substances 0.000 description 2
150000002894 organic compounds Chemical class 0.000 description 2
XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 description 1
WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 description 1
OCUCCJIRFHNWBP-IYEMJOQQSA-L Copper gluconate Chemical class [Cu+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O OCUCCJIRFHNWBP-IYEMJOQQSA-L 0.000 description 1
208000002064 Dental Plaque Diseases 0.000 description 1
239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
240000004760 Pimpinella anisum Species 0.000 description 1
235000012550 Pimpinella anisum Nutrition 0.000 description 1
241001516739 Platonia insignis Species 0.000 description 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
239000005864 Sulphur Chemical group 0.000 description 1
244000290333 Vanilla fragrans Species 0.000 description 1
235000009499 Vanilla fragrans Nutrition 0.000 description 1
235000012036 Vanilla tahitensis Nutrition 0.000 description 1
239000003082 abrasive agent Substances 0.000 description 1
238000009825 accumulation Methods 0.000 description 1
LFVVNPBBFUSSHL-UHFFFAOYSA-N alexidine Chemical compound CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC LFVVNPBBFUSSHL-UHFFFAOYSA-N 0.000 description 1
229950010221 alexidine Drugs 0.000 description 1
239000003242 anti bacterial agent Substances 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 1
229960003333 chlorhexidine gluconate Drugs 0.000 description 1
229940043350 citral Drugs 0.000 description 1
239000001071 citrus reticulata blanco var. mandarin Substances 0.000 description 1
239000012153 distilled water Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
229940073505 ethyl vanillin Drugs 0.000 description 1
239000013020 final formulation Substances 0.000 description 1
WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 description 1
208000007565 gingivitis Diseases 0.000 description 1
125000005842 heteroatom Chemical group 0.000 description 1
-1 hqmectants Substances 0.000 description 1
235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
238000010348 incorporation Methods 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
239000000463 material Substances 0.000 description 1
125000004433 nitrogen atom Chemical group N* 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
239000002245 particle Substances 0.000 description 1
239000007967 peppermint flavor Substances 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
229960001860 salicylate Drugs 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
239000013589 supplement Substances 0.000 description 1
235000019640 taste Nutrition 0.000 description 1
239000002562 thickening agent Substances 0.000 description 1
239000010678 thyme oil Substances 0.000 description 1
239000004408 titanium dioxide Substances 0.000 description 1
235000012141 vanillin Nutrition 0.000 description 1
MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Birds (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Oral & Maxillofacial Surgery (AREA)
Cosmetics (AREA)

CA000338888A 1978-11-01 1979-10-31 Bactericide cathionique avec additif de sapidite employe dans les produits d'hygiene buccale Expired CA1120861A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB7842818		1978-11-01
GB42818/78		1978-11-01

Publications (1)

Publication Number	Publication Date
CA1120861A true CA1120861A (fr)	1982-03-30

Family

ID=10500739

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000338888A Expired CA1120861A (fr)	1978-11-01	1979-10-31	Bactericide cathionique avec additif de sapidite employe dans les produits d'hygiene buccale

Country Status (4)

Country	Link
CA (1)	CA1120861A (fr)
DE (1)	DE2944021A1 (fr)
FR (1)	FR2440189A1 (fr)
GB (1)	GB2035084B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4431631A (en) *	1983-01-03	1984-02-14	Colgate-Palmolive Company	Aqueous oral solution
DE3502830A1 (de) *	1984-02-09	1985-08-14	Colgate Palmolive Co	Zahnpflegemittelzusammensetzung
US4574081A (en) *	1984-09-25	1986-03-04	Colgate-Palmolive Co.	Antiplaque dentifrice having improved flavor
AU6656886A (en) *	1985-12-16	1987-06-18	Cilag A.G.	Pharmaceutical composition of suprofen
JPH0774139B2 (ja) *	1986-02-05	1995-08-09	ライオン株式会社	口腔用組成物
ZA872857B (en) *	1986-05-02	1987-11-25	Warner Lambert Co	Composition and method to inhibit the growth of organisms by the use of bis-biguanido hexanes and essential oil mixture combinations
US6143281A (en) *	1987-03-31	2000-11-07	Smithkline Beecham P.L.C.	Dentifrice compositions
US4945087A (en) *	1988-03-31	1990-07-31	Warner-Lambert Company	Taste masking of thymol
US5094843A (en) *	1990-09-10	1992-03-10	Beecham Inc.	Antimicrobial toothpaste
AU3890395A (en) *	1994-11-17	1996-06-17	Warner-Lambert Company	Antimicrobial oral compositions
WO2000016736A1 (fr) *	1998-09-23	2000-03-30	Unilever N.V.	Compositions convenant aux soins buccaux
GB2349817A (en) *	1999-03-12	2000-11-15	K T Lalvani	uSE OF MASKING AGENTS WITH CAPSULES
EP2621462B1 (fr) *	2010-10-01	2020-02-12	The Procter and Gamble Company	Compositions pour soins bucco-dentaires à saveur améliorée
WO2025176310A1 (fr) *	2024-02-23	2025-08-28	Symrise Ag	Composition d'arôme
DE102025102984A1 (de)	2025-01-28	2026-07-30	Katharina Klein	Mundöl-Zusammensetzung zur Anwendung in der Mundhygiene oder Zahnpflege

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1367892A (en) *	1970-11-27	1974-09-25	Colgate Palmolive Co	Dentifrice compositions
ZA721351B (en) *	1971-03-22	1973-10-31	Colgate Palmolive Co	Stable dentifrice
US3876759A (en) *	1973-01-04	1975-04-08	Colgate Palmolive Co	Method of making clear lemon-flavored mouthwash

1979
- 1979-10-30 FR FR7926869A patent/FR2440189A1/fr not_active Withdrawn
- 1979-10-31 CA CA000338888A patent/CA1120861A/fr not_active Expired
- 1979-10-31 GB GB7937628A patent/GB2035084B/en not_active Expired
- 1979-10-31 DE DE19792944021 patent/DE2944021A1/de not_active Withdrawn

Also Published As

Publication number	Publication date
FR2440189A1 (fr)	1980-05-30
GB2035084B (en)	1983-02-09
DE2944021A1 (de)	1980-05-14
GB2035084A (en)	1980-06-18

Legal Events

Date	Code	Title	Description
1999-03-30	MKEX	Expiry

Publication	Publication Date	Title
JP3721539B2 (ja)	2005-11-30	殺菌性歯磨き
US3947570A (en)	1976-03-30	Oral product
US3720762A (en)	1973-03-13	Spilanthol-containing compositions for oral use
US4476107A (en)	1984-10-09	Mouthwash composition
DE69712054T2 (de)	2002-10-24	Zahnpflegemittel gegen zahnsteinbildung enthaltend hochlösliche pyrophosphate
JP5381685B2 (ja)	2014-01-08	歯磨剤組成物
CA1262687A (fr)	1989-11-07	Dentifrice antiplaque a saveur amelioree
GB2035084A (en)	1980-06-18	Flavouring oral products
WO2011055708A1 (fr)	2011-05-12	Composition liquide contenant de l'isopropyl méthyl phénol pour la cavité buccale
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US20060013837A1 (en)	2006-01-19	Flavour compositions
JPWO2018151076A1 (ja)	2019-12-12	ジェル状歯磨剤組成物及びそのべたつき抑制剤
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JP4158036B2 (ja)	2008-10-01	歯磨剤組成物及びその製造方法
US4623537A (en)	1986-11-18	Oral hygiene compositions
JP7803275B2 (ja)	2026-01-21	口腔用組成物
JPS60163810A (ja)	1985-08-26	練り歯磨組成物
JP3491027B2 (ja)	2004-01-26	口腔用組成物
JP2005041787A (ja)	2005-02-17	歯磨剤組成物
JP2024095188A (ja)	2024-07-10	口腔用組成物