CA1126162A - Dentifrice contenant de la silice precipitee amorphe, exempte de fixateurs de fluorure - Google Patents

Dentifrice contenant de la silice precipitee amorphe, exempte de fixateurs de fluorure

Info

Publication number: CA1126162A
Authority: CA; Canada
Prior art keywords: cream; dentifrice; weight; amount; dentifrice cream
Prior art date: 1980-05-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA351,423A

Other languages

English (en)

Inventor

Eric Blaser

Suhas Ambike

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Canada Inc

Original Assignee

Warner Lambert Canada Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-05-07

Filing date

1980-05-07

Publication date

1982-06-22

1980-05-07 Application filed by Warner Lambert Canada Inc filed Critical Warner Lambert Canada Inc

1980-05-07 Priority to CA351,423A priority Critical patent/CA1126162A/fr

1982-06-22 Application granted granted Critical

1982-06-22 Publication of CA1126162A publication Critical patent/CA1126162A/fr

Status Expired legal-status Critical Current

Links

VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 title claims abstract description 49
239000000551 dentifrice Substances 0.000 title claims abstract description 31
239000000377 silicon dioxide Substances 0.000 title claims abstract description 23
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 title abstract description 15
239000002516 radical scavenger Substances 0.000 title description 2
239000006071 cream Substances 0.000 claims abstract description 34
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims abstract description 5
229910052782 aluminium Inorganic materials 0.000 claims abstract description 5
238000010521 absorption reaction Methods 0.000 claims abstract description 4
230000000675 anti-caries Effects 0.000 claims abstract description 4
229940091249 fluoride supplement Drugs 0.000 claims description 17
239000000203 mixture Substances 0.000 claims description 17
239000003795 chemical substances by application Substances 0.000 claims description 12
238000005498 polishing Methods 0.000 claims description 10
239000011230 binding agent Substances 0.000 claims description 9
GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 8
-1 fluoride compound Chemical class 0.000 claims description 8
XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 claims description 7
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 7
DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 7
239000001768 carboxy methyl cellulose Substances 0.000 claims description 7
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 7
229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 7
229960004711 sodium monofluorophosphate Drugs 0.000 claims description 7
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 4
239000002202 Polyethylene glycol Substances 0.000 claims description 4
BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical group [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims description 4
239000003906 humectant Substances 0.000 claims description 4
229920001223 polyethylene glycol Polymers 0.000 claims description 4
239000000600 sorbitol Substances 0.000 claims description 4
239000004094 surface-active agent Substances 0.000 claims description 4
239000004408 titanium dioxide Substances 0.000 claims description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 3
DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 3
239000000796 flavoring agent Substances 0.000 claims description 3
235000011187 glycerol Nutrition 0.000 claims description 3
235000013615 non-nutritive sweetener Nutrition 0.000 claims description 3
239000003921 oil Substances 0.000 claims description 3
239000008363 phosphate buffer Substances 0.000 claims description 3
239000000049 pigment Substances 0.000 claims description 3
235000019333 sodium laurylsulphate Nutrition 0.000 claims description 3
241000894007 species Species 0.000 claims description 3
UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical group [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 claims description 2
235000014749 Mentha crispa Nutrition 0.000 claims description 2
244000246386 Mentha pulegium Species 0.000 claims description 2
235000016257 Mentha pulegium Nutrition 0.000 claims description 2
244000078639 Mentha spicata Species 0.000 claims description 2
235000004357 Mentha x piperita Nutrition 0.000 claims description 2
239000004141 Sodium laurylsulphate Substances 0.000 claims description 2
239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 claims description 2
235000001050 hortel pimenta Nutrition 0.000 claims description 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 2
229960001462 sodium cyclamate Drugs 0.000 claims description 2
235000013355 food flavoring agent Nutrition 0.000 claims 2
239000000341 volatile oil Substances 0.000 claims 2
CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims 1
239000000606 toothpaste Substances 0.000 abstract description 23
229940034610 toothpaste Drugs 0.000 abstract description 16
238000004140 cleaning Methods 0.000 abstract description 3
230000000694 effects Effects 0.000 abstract description 3
238000009472 formulation Methods 0.000 description 9
RBLGLDWTCZMLRW-UHFFFAOYSA-K dicalcium;phosphate;dihydrate Chemical compound O.O.[Ca+2].[Ca+2].[O-]P([O-])([O-])=O RBLGLDWTCZMLRW-UHFFFAOYSA-K 0.000 description 4
229910019142 PO4 Inorganic materials 0.000 description 3
WINXNKPZLFISPD-UHFFFAOYSA-M Saccharin sodium Chemical compound [Na+].C1=CC=C2C(=O)[N-]S(=O)(=O)C2=C1 WINXNKPZLFISPD-UHFFFAOYSA-M 0.000 description 3
JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 description 3
239000010452 phosphate Substances 0.000 description 3
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 3
230000009257 reactivity Effects 0.000 description 3
239000003082 abrasive agent Substances 0.000 description 2
PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 2
229940043256 calcium pyrophosphate Drugs 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
235000019821 dicalcium diphosphate Nutrition 0.000 description 2
229910000397 disodium phosphate Inorganic materials 0.000 description 2
235000019800 disodium phosphate Nutrition 0.000 description 2
238000000034 method Methods 0.000 description 2
230000001225 therapeutic effect Effects 0.000 description 2
MOMKYJPSVWEWPM-UHFFFAOYSA-N 4-(chloromethyl)-2-(4-methylphenyl)-1,3-thiazole Chemical compound C1=CC(C)=CC=C1C1=NC(CCl)=CS1 MOMKYJPSVWEWPM-UHFFFAOYSA-N 0.000 description 1
235000019739 Dicalciumphosphate Nutrition 0.000 description 1
238000005299 abrasion Methods 0.000 description 1
239000000654 additive Substances 0.000 description 1
230000000996 additive effect Effects 0.000 description 1
239000001506 calcium phosphate Substances 0.000 description 1
239000004075 cariostatic agent Substances 0.000 description 1
210000004268 dentin Anatomy 0.000 description 1
NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 description 1
229940038472 dicalcium phosphate Drugs 0.000 description 1
229910000390 dicalcium phosphate Inorganic materials 0.000 description 1
235000019634 flavors Nutrition 0.000 description 1
239000012535 impurity Substances 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
230000009965 odorless effect Effects 0.000 description 1
229940057838 polyethylene glycol 4000 Drugs 0.000 description 1
239000000843 powder Substances 0.000 description 1
239000008213 purified water Substances 0.000 description 1
230000002285 radioactive effect Effects 0.000 description 1
230000002000 scavenging effect Effects 0.000 description 1
235000012239 silicon dioxide Nutrition 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
AQMNWCRSESPIJM-UHFFFAOYSA-M sodium metaphosphate Chemical compound [Na+].[O-]P(=O)=O AQMNWCRSESPIJM-UHFFFAOYSA-M 0.000 description 1
235000019983 sodium metaphosphate Nutrition 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Oral & Maxillofacial Surgery (AREA)
Chemical & Material Sciences (AREA)
Inorganic Chemistry (AREA)
Birds (AREA)
Epidemiology (AREA)
Cosmetics (AREA)

CA351,423A 1980-05-07 1980-05-07 Dentifrice contenant de la silice precipitee amorphe, exempte de fixateurs de fluorure Expired CA1126162A (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA351,423A CA1126162A (fr)	1980-05-07	1980-05-07	Dentifrice contenant de la silice precipitee amorphe, exempte de fixateurs de fluorure

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CA351,423A CA1126162A (fr)	1980-05-07	1980-05-07	Dentifrice contenant de la silice precipitee amorphe, exempte de fixateurs de fluorure

Publications (1)

Publication Number	Publication Date
CA1126162A true CA1126162A (fr)	1982-06-22

Family

ID=4116880

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA351,423A Expired CA1126162A (fr)	1980-05-07	1980-05-07	Dentifrice contenant de la silice precipitee amorphe, exempte de fixateurs de fluorure

Country Status (1)

Country	Link
CA (1)	CA1126162A (fr)

1980
- 1980-05-07 CA CA351,423A patent/CA1126162A/fr not_active Expired

Legal Events

Date	Code	Title	Description
1999-06-22	MKEX	Expiry

Publication	Publication Date	Title
AU597384B2 (en)	1990-05-31	Oral hygiene composition containing an antibacterial agent
US4314990A (en)	1982-02-09	Toothpaste compositions
US4254101A (en)	1981-03-03	Toothpaste compositions
US5213790A (en)	1993-05-25	Methods of reducing plaque and gingivitis with reduced staining
AU632484B2 (en)	1993-01-07	Oral compositions
EP0609215B1 (fr)	1995-08-30	Dentifrices anti-tartre
US3966863A (en)	1976-06-29	Oral hygiene compositions
US3227617A (en)	1966-01-04	Fluoride dentifrice composition
JPH059404B2 (fr)	1993-02-04
US5389360A (en)	1995-02-14	Oral compositions
GB2188548A (en)	1987-10-07	Oral hygiene compositions
JPS59205308A (ja)	1984-11-20	歯および口腔の保護製剤
US4193988A (en)	1980-03-18	Oral hygiene compositions
US5112600A (en)	1992-05-12	Compositions
FI58066C (fi)	1980-12-10	Fluorhaltigt tandvaordsmedel
US5015465A (en)	1991-05-14	Oral hygiene compositions
US4256730A (en)	1981-03-17	Oral compositions
US4415550A (en)	1983-11-15	Treatment-and-prophylactic tooth paste possessing anticarious effect
US4132773A (en)	1979-01-02	Dentifrices
KR20050047115A (ko)	2005-05-19	활석을 함유하는 치약 조성물
CA1126162A (fr)	1982-06-22	Dentifrice contenant de la silice precipitee amorphe, exempte de fixateurs de fluorure
US5496539A (en)	1996-03-05	Oral compositions
EP0311259A2 (fr)	1989-04-12	Compositions buccales
JPS6041047B2 (ja)	1985-09-13	歯磨組成物
US4419342A (en)	1983-12-06	Dentifrice preparation