CA1163938A - Traitement d'une maladie due a des protozoaires, grace a des 3-(5'-ribonucleotides) de lincomycine - Google Patents

Traitement d'une maladie due a des protozoaires, grace a des 3-(5'-ribonucleotides) de lincomycine

Info

Publication number
CA1163938A
CA1163938A CA000398814A CA398814A CA1163938A CA 1163938 A CA1163938 A CA 1163938A CA 000398814 A CA000398814 A CA 000398814A CA 398814 A CA398814 A CA 398814A CA 1163938 A CA1163938 A CA 1163938A
Authority
CA
Canada
Prior art keywords
compound
general formula
ribonucleotide
acceptable salt
prepared
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000398814A
Other languages
English (en)
Inventor
Alexander D. Argoudelis
David W. Stroman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/255,541 external-priority patent/US4368193A/en
Priority claimed from US06/255,542 external-priority patent/US4383109A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of CA1163938A publication Critical patent/CA1163938A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/305—Pyrimidine nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA000398814A 1981-04-20 1982-03-19 Traitement d'une maladie due a des protozoaires, grace a des 3-(5'-ribonucleotides) de lincomycine Expired CA1163938A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US255,542 1981-04-20
US06/255,541 US4368193A (en) 1981-04-20 1981-04-20 Process for treating malaria
US06/255,542 US4383109A (en) 1981-04-20 1981-04-20 Lincomycin nucleotides
US255,541 1981-04-20

Publications (1)

Publication Number Publication Date
CA1163938A true CA1163938A (fr) 1984-03-20

Family

ID=26944757

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000398814A Expired CA1163938A (fr) 1981-04-20 1982-03-19 Traitement d'une maladie due a des protozoaires, grace a des 3-(5'-ribonucleotides) de lincomycine

Country Status (15)

Country Link
KR (1) KR880002416B1 (fr)
AU (1) AU545748B2 (fr)
CA (1) CA1163938A (fr)
CH (1) CH653037A5 (fr)
DE (1) DE3213921A1 (fr)
ES (1) ES511499A0 (fr)
FR (1) FR2504142B1 (fr)
GB (1) GB2097002B (fr)
HU (1) HU191085B (fr)
IL (1) IL65385A (fr)
IT (1) IT1151719B (fr)
NL (1) NL8201595A (fr)
PL (1) PL133485B1 (fr)
SE (1) SE459861B (fr)
SU (1) SU1303036A3 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3671647A (en) * 1971-03-24 1972-06-20 Upjohn Co Lincomycin 3-nucleotides and the salts thereof

Also Published As

Publication number Publication date
KR830010195A (ko) 1983-12-26
CH653037A5 (de) 1985-12-13
HU191085B (en) 1987-01-28
ES8308927A1 (es) 1983-10-01
IL65385A (en) 1985-10-31
SU1303036A3 (ru) 1987-04-07
KR880002416B1 (ko) 1988-11-08
FR2504142B1 (fr) 1985-07-26
SE8202433L (sv) 1982-10-21
PL133485B1 (en) 1985-06-29
FR2504142A1 (fr) 1982-10-22
NL8201595A (nl) 1982-11-16
IL65385A0 (en) 1982-05-31
DE3213921A1 (de) 1983-01-05
IT1151719B (it) 1986-12-24
GB2097002B (en) 1985-06-19
ES511499A0 (es) 1983-10-01
PL236043A1 (fr) 1982-11-08
GB2097002A (en) 1982-10-27
AU8198882A (en) 1982-10-28
IT8220810A0 (it) 1982-04-19
SE459861B (sv) 1989-08-14
AU545748B2 (en) 1985-08-01

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Legal Events

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