CA1164004A - Phosphorane servant d'intermediaire dans la preparation du penem, un antibiotique - Google Patents

Phosphorane servant d'intermediaire dans la preparation du penem, un antibiotique

Info

Publication number: CA1164004A
Authority: CA; Canada
Prior art keywords: alkyl; alk; phenyl; hydrogen; formula
Prior art date: 1978-12-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000412517A

Other languages

English (en)

Inventor

Marcel Menard

Alain Martel

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Squibb Co

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-12-18

Filing date

1982-09-29

Publication date

1984-03-20

1979-09-21 Priority claimed from US06/077,886 external-priority patent/US4282150A/en

1982-09-29 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1982-09-29 Priority to CA000412517A priority Critical patent/CA1164004A/fr

1984-03-20 Application granted granted Critical

1984-03-20 Publication of CA1164004A publication Critical patent/CA1164004A/fr

Status Expired legal-status Critical Current

Links

239000000543 intermediate Substances 0.000 title abstract 3
239000003242 anti bacterial agent Substances 0.000 title abstract 2
XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 title 1
229940088710 antibiotic agent Drugs 0.000 title 1
HHXMXAQDOUCLDN-RXMQYKEDSA-N penem Chemical compound S1C=CN2C(=O)C[C@H]21 HHXMXAQDOUCLDN-RXMQYKEDSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 claims abstract 12
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract 11
229910052739 hydrogen Inorganic materials 0.000 claims abstract 10
239000001257 hydrogen Substances 0.000 claims abstract 10
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 6
125000002947 alkylene group Chemical group 0.000 claims abstract 6
150000001875 compounds Chemical class 0.000 claims abstract 5
-1 alkyl radical Chemical class 0.000 claims abstract 4
150000002431 hydrogen Chemical group 0.000 claims abstract 4
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims abstract 3
125000001424 substituent group Chemical group 0.000 claims abstract 3
239000003795 chemical substances by application Substances 0.000 claims abstract 2
229910001385 heavy metal Inorganic materials 0.000 claims abstract 2
150000002148 esters Chemical group 0.000 claims 2
239000000126 substance Substances 0.000 claims 2
239000012467 final product Substances 0.000 claims 1
239000007858 starting material Substances 0.000 claims 1
125000004185 ester group Chemical group 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
150000002961 penems Chemical class 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
150000003254 radicals Chemical class 0.000 abstract 1

Classifications

- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

CA000412517A 1978-12-18 1982-09-29 Phosphorane servant d'intermediaire dans la preparation du penem, un antibiotique Expired CA1164004A (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA000412517A CA1164004A (fr)	1978-12-18	1982-09-29	Phosphorane servant d'intermediaire dans la preparation du penem, un antibiotique

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US96866378A	1978-12-18	1978-12-18
US968,663		1978-12-18
US06/077,886 US4282150A (en)	1978-12-18	1979-09-21	2,6-Disubstituted penem compounds
US77,886		1979-09-21
CA000342049A CA1136617A (fr)	1978-12-18	1979-12-17	Composes penem substitues en positions 2 et 6
CA000412517A CA1164004A (fr)	1978-12-18	1982-09-29	Phosphorane servant d'intermediaire dans la preparation du penem, un antibiotique

Publications (1)

Publication Number	Publication Date
CA1164004A true CA1164004A (fr)	1984-03-20

Family

ID=27426206

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000412517A Expired CA1164004A (fr)	1978-12-18	1982-09-29	Phosphorane servant d'intermediaire dans la preparation du penem, un antibiotique

Country Status (1)

Country	Link
CA (1)	CA1164004A (fr)

1982
- 1982-09-29 CA CA000412517A patent/CA1164004A/fr not_active Expired

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Legal Events

Date	Code	Title	Description
2001-03-20	MKEX	Expiry